为线粒体注入能量，预防老化过程中的行动能力丧失：理由与假设。

IF 4.9 2区医学 Q1 PHYSIOLOGY

Exercise and Sport Sciences Reviews Pub Date : 2023-07-01 Epub Date: 2023-04-14 DOI:10.1249/JES.0000000000000315

Qu Tian, Philip R Lee, Keenan A Walker, Luigi Ferrucci

引用次数: 0

摘要

根据我们小组和其他小组最近的研究，我们假设衰老过程中的线粒体功能障碍可能是肌肉骨骼和中枢神经系统缺陷导致行动能力下降的根本原因。线粒体功能障碍可能是预防衰老过程中行动能力下降的治疗目标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Energizing Mitochondria to Prevent Mobility Loss in Aging: Rationale and Hypotheses.

Based on recent studies from our group and others, we hypothesize that mitochondrial dysfunction during aging may be the root cause of mobility decline through deficits in the musculoskeletal and central nervous systems. Mitochondrial dysfunction could be a therapeutic target to prevent mobility decline in aging.

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来源期刊

Exercise and Sport Sciences Reviews 社会科学-生理学

CiteScore

10.70

自引率

1.80%

发文量

期刊介绍： Exercise and Sport Sciences Reviews made the transition from an annual hardcover series book to a quarterly journal in January 2000. The mission of this American College of Sports Medicine publication is to provide premier quarterly reviews of the most contemporary scientific, medical, and research-based topics emerging in the field of sports medicine and exercise science. The publication strives to provide the most relevant, topical information to students, professors, clinicians, scientists, and professionals for practical and research applications.