The Importance of Muscle Capillarization for Optimizing Satellite Cell Plasticity.

IF 4.9 2区 医学 Q1 PHYSIOLOGY
Joshua P Nederveen, Milan W Betz, Tim Snijders, Gianni Parise
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引用次数: 12

Abstract

Satellite cells are essential for skeletal muscle regeneration, repair, and adaptation. The activity of satellite cells is influenced by their interactions with muscle-resident endothelial cells. We postulate that the microvascular network between muscle fibers plays a critical role in satellite cell function. Exercise-induced angiogenesis can mitigate the decline in satellite cell function with age.

肌肉毛细血管化对优化卫星细胞可塑性的重要性。
卫星细胞对骨骼肌的再生、修复和适应至关重要。卫星细胞的活性受其与肌内内皮细胞相互作用的影响。我们推测肌纤维之间的微血管网络在卫星细胞的功能中起着关键作用。运动诱导的血管生成可以缓解卫星细胞功能随年龄的下降。
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来源期刊
Exercise and Sport Sciences Reviews
Exercise and Sport Sciences Reviews 社会科学-生理学
CiteScore
10.70
自引率
1.80%
发文量
72
期刊介绍: Exercise and Sport Sciences Reviews made the transition from an annual hardcover series book to a quarterly journal in January 2000. The mission of this American College of Sports Medicine publication is to provide premier quarterly reviews of the most contemporary scientific, medical, and research-based topics emerging in the field of sports medicine and exercise science. The publication strives to provide the most relevant, topical information to students, professors, clinicians, scientists, and professionals for practical and research applications.
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