Postepy Dermatologii I Alergologii最新文献

{"title":"Rapid desensitization for human serum albumin (Grifols^®) hypersensitivity.","authors":"Mattia Cristallo, Federico Spataro, Nada Chaoul, Eustachio Nettis, Attilio Di Girolamo","doi":"10.5114/ada.2024.145434","DOIUrl":"10.5114/ada.2024.145434","url":null,"abstract":"","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"41 6","pages":"634-636"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143060589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SCALPDEX Questionnaire: creation and validation of the Polish language version.","authors":"Agnieszka Otlewska-Szpotowicz, Łukasz Matusiak, Joanna Salomon, Adam Reich, Jacek C Szepietowski","doi":"10.5114/ada.2024.142595","DOIUrl":"10.5114/ada.2024.142595","url":null,"abstract":"<p><strong>Introduction: </strong>Assessing the quality of life (QoL) in patients with various diseases is essential for understanding their well-being and guiding clinical management. Dermatological conditions, particularly those affecting the scalp, significantly impact QoL due to their visible nature, which can affect appearance and social interactions. While general QoL instruments like the Dermatology Life Quality Index (DLQI) exist, disease-specific tools like SCALPDEX are necessary for capturing the unique challenges faced by patients with scalp disorders.</p><p><strong>Aim: </strong>To translate and validate the SCALPDEX questionnaire into the Polish language to facilitate its use among Polish-speaking clinicians.</p><p><strong>Material and methods: </strong>A standard forward and backward translation procedure was used to convert the original English version of SCALPDEX into the Polish language. The validation of the Polish version was performed in a group of 60 patients with scalp dermatoses who were asked to fill in the questionnaire twice within an interval of 7 days for reassessment to evaluate test-retest reliability. During the first completion the patients were additionally asked to fill in an already existing Polish version of Dermatology Life Quality Index (DLQI), which was used as a reference questionnaire.</p><p><strong>Results: </strong>The Polish version of the SCAPLDEX questionnaire showed a very good internal consistency (Cronbach α = 0.94) and reproducibility (ICC = 0.94), with a strong correlation between SCALPDEX and DLQI scores (<i>R</i> = 0.74, <i>p</i> < 0.0001).</p><p><strong>Conclusions: </strong>The Polish version of SCALPDEX has proven to be a reliable and valid instrument for assessing the QoL in patients with scalp disorders.</p>","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"41 6","pages":"590-593"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Specificity and sensitivity of questionnaires in the diagnosis of allergic diseases.","authors":"Edyta Krzych-Fałta, Oksana Wojas, Filip Raciborski, Konrad Furmańczyk, Mariola Chrzanowska, Bolesław Samoliński, Agnieszka Lipiec, Barbara Piekarska, Mariusz Gujski","doi":"10.5114/ada.2024.143534","DOIUrl":"10.5114/ada.2024.143534","url":null,"abstract":"<p><strong>Introduction: </strong>Due to their widespread character, allergic diseases are a significant challenge in the field of public health and clinical practice. The available clinimetric tools, including standardized and validated questionnaires, play an important role in determining the incidence of a particular allergic disease in the targeted population.</p><p><strong>Aim: </strong>We attempted to evaluate the specificity and sensitivity of modified and standardized questions from the ISSAC and ECRHS questionnaires in the diagnosis of allergic diseases.</p><p><strong>Material and methods: </strong>We examined a total number of 1,000 respondents classified into the following age groups: 6-10, 11-15, and 16-19 years. Modified ISSAC and ECRHS questionnaires were implemented to verify the effectiveness of diagnosing allergic diseases.</p><p><strong>Results: </strong>Among individuals aged from 6 to 10 years, the specificity and sensitivity of diagnosing allergic rhinitis were 0.84 and 0.50; for asthma 0.64 and 0.85, for atopic dermatitis 0.90 and 0.42, and for food allergy 0.42 and 0.85, respectively. Respondents aged 11-15 years presented the following values of specificity and sensitivity: 0.83 and 0.46 for allergic rhinitis, 0.45 and 0.87 for asthma, 0.89 and 0.43 for atopic dermatitis, and 0.61 and 0.80 for food allergies, respectively. Finally, among patients from 16 to 19 years of age, the specificity and sensitivity of validated questionnaires as assessment tools in diagnosing allergic rhinitis were 0.91 and 0.39, for asthma 0.35 and 0.89, for atopic dermatitis 1.0 and 0.45, and for food allergy 0.67 and 0.85, respectively.</p><p><strong>Conclusions: </strong>The modified and standardized questions included in the ISSAC and ECRHS questionnaires are a valuable tool for determining the scale of allergic diseases. However, as these clinical tools are characterized by varying specificity and sensitivity, it is recommended that such tests be verified by clinical examination.</p>","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"41 6","pages":"594-603"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative assessment of alcaftadine and olopatadine for allergic conjunctivitis: a meta-analysis.","authors":"Xiaojuan Fu, Peijie Xu, Di Lu","doi":"10.5114/ada.2024.144166","DOIUrl":"10.5114/ada.2024.144166","url":null,"abstract":"<p><strong>Introduction: </strong>It is unclear to compare the efficacy of alcaftadine versus olopatadine for patients with allergic conjunctivitis, and this meta-analysis aims to perform the comparative assessment of their efficacy for allergic conjunctivitis.</p><p><strong>Methods: </strong>We systematically searched PubMed, Embase, Web of Science, EBSCO, and Cochrane library databases, and included randomized controlled trials (RCTs) comparing alcaftadine with olopatadine for allergic conjunctivitis. The random-effect model was used for the significant heterogeneity, and otherwise the fixed-effect model was used.</p><p><strong>Results: </strong>Twelve RCTs and 1064 patients with allergic conjunctivitis were included in this meta-analysis. In comparison with olopatadine intervention, alcaftadine intervention demonstrated a comparable ocular symptom score on 3 days (MD = -0.06; 95% CI = -0.19 to 0.07; <i>p</i> = 0.35), but was able to significantly decrease the ocular symptom score on 7 days (MD = -0.09; 95% CI = -0.16 to -0.01; <i>p</i> = 0.03), ocular symptom score on 14 days (MD = -0.25; 95% CI = -0.37 to -0.12; <i>p</i> < 0.0001) and conjunctival hyperaemia score on 14 days (MD = -0.04; 95% CI = -0.05 to -0.03; <i>p</i> < 0.00001). These two groups had similar incidence of adverse events (OR = 0.61; 95% CI = 0.34 to 1.09; <i>p</i> = 0.10).</p><p><strong>Conclusions: </strong>Alcaftadine had better capability to treat allergic conjunctivitis compared to olopatadine.</p>","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"41 6","pages":"560-565"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11770579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Available questionnaires do not cover important aspects of quality of life of patients with cutaneous T-cell lymphoma: evaluation of the quality of life of Polish patients with cutaneous T-cell lymphoma.","authors":"Agnieszka Giza, Małgorzata Sokołowska-Wojdyło, Hanna Ciepłuch, Berenika Olszewska, Roman J Nowicki, Karol Kołkowski","doi":"10.5114/ada.2024.145289","DOIUrl":"10.5114/ada.2024.145289","url":null,"abstract":"<p><strong>Introduction: </strong>Cutaneous T-cell lymphoma (CTCL) has a significant impact on patients' quality of life (QoL). Most studies have measured QoL using validated questionnaires that are not specific to patients with CTCL. Furthermore, clinician-perceived QoL in CTCL patients has never been measured before.</p><p><strong>Aim: </strong>The quantitative and qualitative evaluation of QoL of the Polish CTCL patients and doctors and checking the impact of the disease on their daily functioning.</p><p><strong>Material and methods: </strong>Structured anonymous questionnaires were administered to Polish patients diagnosed with CTCL and their physicians. The questionnaire was designed on the basis of interviews with two physicians, experts in the field, and 2 patients. Patients completed the questionnaire and the Skindex-29 survey in person.</p><p><strong>Results: </strong>Our patients have been moderately affected in the physical domain and significantly affected in the emotional and functional domains according to Skindex-29, whereas according to the results of our questionnaire, the most affected domains are the physical and emotional domains. The biggest inconvenience for patients is commuting to another city and time spent on visits and tests. We are the first to report that 57% of patients try to distract themselves from thinking about the diagnosis, 55% hope for a normal life and 64% miss previous lifestyle and/or opportunities.</p><p><strong>Conclusions: </strong>Polish physicians underestimated the impact of the disease on insomnia, sleep disturbance and patient independence. Although the Skindex-29 is a widely used and validated tool, it may not fully capture all aspects of QoL in patients with CTCL.</p>","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"42 2","pages":"156-163"},"PeriodicalIF":1.4,"publicationDate":"2024-11-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163967/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Apoptosis and PTX3 in lichen planus.","authors":"Ibrahim H Yavuz, Göknur Özaydın Yavuz, Nazlı Caf, Mustafa Tümtürk, Harbiye Dilek Canat, Mehmet Onur Gökalp","doi":"10.5114/ada.2024.145205","DOIUrl":"10.5114/ada.2024.145205","url":null,"abstract":"<p><strong>Introduction: </strong>Lichen planus (LP) is considered a T cell-mediated autoimmune disease although its aetiology remains unknown. Cytotoxic T cells play a central role in the pathogenesis of LP and these cells are known to significantly induce apoptosis in basal keratinocytes.</p><p><strong>Aim: </strong>To correlate pentraxin 3 (PTX3) with apoptosis in basal cell keratinocytes in LP and to determine whether it is a marker in this disease.</p><p><strong>Material and methods: </strong>Inclusion criteria were as follows: (i) providing written consent for participation, (ii) presence of typical clinical findings (livid-red, violaceous, flat-topped polygonal papules and plaques, fern appearance in the oral mucosa, flexural involvement, and Wickham's striae) and (iii) histopathological confirmation of LP.</p><p><strong>Results: </strong>A total of 60 participants, 30 patients and 30 controls, were included in the study. No difference was found between groups in terms of age and gender. There was a significant difference in PTX3 levels between groups. As to patients with LP, 21 (70%) patients had skin involvement only, 2 (6.7%) patients had mucosal involvement only, and 7 (23.3%) patients had both skin and mucosal involvement of LP.</p><p><strong>Conclusions: </strong>PTX3 may be associated with apoptosis in LP. Although there are no data on the usability of PTX3 as a specific marker of LP, the present study aimed to demonstrate its usability as a marker of active LP.</p>","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"42 2","pages":"171-174"},"PeriodicalIF":1.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitivity of serum galactomannan antigen in the diagnosis of invasive aspergillosis in patients with obstructive pulmonary diseases (asthma and chronic obstructive pulmonary diseases).","authors":"Xiaoyan Hu, Xiaoling Hu, Yangdan Zhu, Huijia Hu, Zhuoping Wang","doi":"10.5114/ada.2024.145208","DOIUrl":"10.5114/ada.2024.145208","url":null,"abstract":"<p><strong>Introduction: </strong>Adverse clinical outcomes often result from the concomitant presence of invasive pulmonary aspergillosis (IPA) in patients with obstructive pulmonary diseases (asthma and chronic obstructive pulmonary diseases (COPD)).</p><p><strong>Aim: </strong>This work was developed to assess the risk factors (RFs) for patients with concurrent IPA and the diagnostic sensitivity of existing detection methods.</p><p><strong>Material and methods: </strong>This was a case control study on patients with acute exacerbation of obstructive pulmonary diseases (OPD) hospitalized from January 2022 to December 2023; patients were categorized into an IPA group (<i>n</i> = 39) and a non-IPA group (<i>n</i> = 37) based on test results. Information about smoking history, diabetes history, usage of broad-spectrum antibiotics (BSAs) and corticosteroids, and serum albumin levels were collected. After univariate analysis, a multivariate logistic regression (MLR) analysis was performed. Additionally, the diagnostic sensitivity and specificity of GM antigen, IgG, and IgM detection were compared.</p><p><strong>Results: </strong>Prolonged use of BSAs (≥ 2 weeks) and corticosteroids (≥ 3 weeks), along with low albumin levels emerged as independent RFs for concurrent IPA. The sensitivity of GM antigen detection (64.1%) was the highest among the three methods, with specificity slightly lower than IgG detection (75.68%, 81.08%), yet still not reaching the ideal level.</p><p><strong>Conclusions: </strong>Risk assessment for asthma and COPD patients with concurrent IPA should encompass an evaluation of prolonged antibiotic and steroid use, along with a comprehensive consideration of nutritional and immune status. Current IPA detection methods should be evaluated in conjunction with clinical conditions to enhance diagnostic accuracy.</p>","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"42 2","pages":"183-189"},"PeriodicalIF":1.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant basal cell carcinoma located in the temporal region: delay of the patient's visit because of COVID-19 pandemic.","authors":"Amelia Głowaczewska, Iwona Chlebicka, Zuzanna Pawlak, Jacek C Szepietowski","doi":"10.5114/ada.2024.144485","DOIUrl":"10.5114/ada.2024.144485","url":null,"abstract":"","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"42 2","pages":"203-205"},"PeriodicalIF":1.4,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classical and biological treatments in mycosis fungoides/Sézary syndrome. New horizons in oncodermatology.","authors":"Hanna R Cisoń, Rafał K Białynicki-Birula","doi":"10.5114/ada.2024.144999","DOIUrl":"10.5114/ada.2024.144999","url":null,"abstract":"<p><p>In the strategic management of mycosis fungoides (MF)/Sézary syndrome (SS), an interdisciplinary framework is essential. The regimen typically encompasses dermatological-specific interventions, biologic response modulators, and, in advanced scenarios, systemic chemotherapeutic entities. This might integrate biologic response agents like bexarotene, histone deacetylase inhibitors such as romidepsin, and specialized monoclonal antibodies or conjugates, notably mogamulizumab and brentuximab vedotin. Decisions in therapeutic avenues are intricately individualized, considering determinants like patient age, functional health metrics, disease scope, evolutionary trajectory and previous therapeutic exposures. The high-frequency ultrasound seems to be a useful tool for monitoring infiltration of the skin. Moreover, ongoing studies are investigating novel therapeutic agents that may demonstrate efficacy in MF/SS.</p>","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"42 2","pages":"125-133"},"PeriodicalIF":1.4,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenging diagnosis of the spectrum of reactive granulomatous dermatitis: two case reports and literature review.","authors":"Barbara Olszewska, Adriana Polańska, Monika Bowszyc-Dmochowska, Ryszard Żaba, Aleksandra Dańczak-Pazdrowska","doi":"10.5114/ada.2024.143435","DOIUrl":"10.5114/ada.2024.143435","url":null,"abstract":"","PeriodicalId":54595,"journal":{"name":"Postepy Dermatologii I Alergologii","volume":"42 2","pages":"206-209"},"PeriodicalIF":1.4,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12163952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}