Retina-The Journal of Retinal and Vitreous Diseases最新文献

{"title":"Retinal Ischemic Perivascular Lesions in the Fellow Eyes of Patients with Central Retinal Artery Occlusion.","authors":"Seda Karaca Adıyeke, Neslişah Kutlu Uzakgider","doi":"10.1097/IAE.0000000000004876","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004876","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the prevalence and characteristics of retinal ischemic perivascular lesions (RIPLs) in the clinically unaffected fellow eyes of patients with unilateral central retinal artery occlusion (CRAO) using spectral-domain optical coherence tomography (SD-OCT).</p><p><strong>Methods: </strong>This retrospective case-control study included 39 fellow eyes of patients with CRAO and 57 age-, sex-, and hypertension-matched healthy controls. Macular SD-OCT scans were assessed for the presence, number, and morphology of RIPLs, classified as narrow (<300 µm, peaked apex) or wide (>300 µm, flattened apex). Between-group comparisons were performed using appropriate parametric/non-parametric tests, and odds ratios (ORs) were calculated for RIPL presence.</p><p><strong>Results: </strong>RIPLs were detected in 29/39 eyes (74.4%) in the CRAO fellow-eye group and 14/57 eyes (24.6%) in controls (p < 0.001). The mean number of lesions per eye was significantly higher in the CRAO group (1.36 ± 1.22) than in controls (0.35 ± 0.73; p < 0.001). Among CRAO fellow eyes with RIPLs, 5 eyes (17.2%) showed wide-type lesions, whereas all lesions in controls were narrow. The odds of RIPL presence were higher in the CRAO group (OR 8.12, 95% CI 3.20-20.57; p < 0.001).</p><p><strong>Conclusions: </strong>Increased RIPL burden in the fellow eyes of CRAO patients suggests that microstructural retinal changes may be detectable even in eyes without clinically evident arterial occlusion. Further longitudinal, multimodal studies are needed to determine the temporal course and underlying mechanisms.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human Amniotic Membrane (hAM) in Macular Hole Repair: A Scoping Review.","authors":"Danielle Solish, Angel Gao, Nadine Cheffi, Efrem Mandelcorn, Tina Felfeli","doi":"10.1097/IAE.0000000000004877","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004877","url":null,"abstract":"<p><strong>Purpose: </strong>This scoping review examines the technique and outcomes for human amniotic membrane (hAM) grafts in macular hole (MHs) repair, an emerging alternative to conventional methods involving pars plana vitrectomy (PPV), internal limiting membrane (ILM) peeling, and gas endotamponade.</p><p><strong>Methods: </strong>A literature search of three databases was conducted on December 5, 2025.</p><p><strong>Results: </strong>66 studies involving 603 eyes were included. Most hAMs were sourced from eye banks or private companies and cut into 1-4 mm grafts using punch biopsies. All participants underwent PPV with ILM peeling. Grafts were commonly placed stromal side down using forceps, viscous injectors or under fluid or perfluorocarbon liquid. Endotamponade agents included SF6, C3F8, and silicone oil. The overall MH closure rate was 96%. Fresh hAM achieved a 100% closure rate, while cryopreserved hAM achieved 95%. Visual improvement was reported in 81% of cases, with the highest gains observed in traumatic MHs. Myopic MHs with retinal detachments had the lowest closure rate (72%). Graft dislocation was the most common complication (3.6%), and no systemic or uveitic complications were reported.</p><p><strong>Conclusion: </strong>hAM grafting demonstrates high anatomical success and visual improvement with minimal complications, suggesting utility in MH repair, particularly in complex or refractory cases.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of sex-specific clinical prediction models for treatment-required retinopathy of prematurity.","authors":"Yuling Xu, Qiaowei Wu, Jing Li, Shiwei Mei, Songfu Feng, Anyi Liang, Ting Su, Ying Fang, Yijun Hu, Lei Liu, Honghua Yu, Xiayin Zhang, Wei Sun","doi":"10.1097/IAE.0000000000004878","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004878","url":null,"abstract":"<p><strong>Purpose: </strong>To develop clinically practical, sex-specific prediction models for identifying TR-ROP, irrespective of fundus photography, and evaluate its generalizability, efficiency, productivity, and interpretability.</p><p><strong>Methods: </strong>We selected premature infants who suffered risk of TR-ROP and received fundus examination between 2012 and 2022. Logistic Regression (LR) Model, Random forest-LR Model and LASSO-LR Model were constructed and the model with the best performance was chosen for predictions of the occurrence of TR-ROP.</p><p><strong>Results: </strong>Among 7,235 preterm infants received ROP screening, 408 (5.63%) were TR-ROP. The median follow-up time was 24 months. Male and female shared some modifiable risk and protective factors, but they also presented independent risk factors. The sex-specific model based on birth weight, gestational age, hypoxic ischemic encephalopathy, multiple births, blood transfusion (male) and birth weight, gestational age, head circumference, cesarean delivery, blood transfusion (female) were selected by LR showed more promising results in the prediction of TR-ROP in the internal validation cohort (male: AUC 0.855-0.981, specificity 0.895; female: AUC 0.950-0.995, specificity 1.000). The performance of the above sex-specific models also demonstrated performance in the external validation cohorts (male: AUC 0.806-0.951, specificity 0.824; female: AUC 0.625-0.919, specificity 0.727). The C-index showed the sex-stratified models displayed better clinical predictive utility than the overall model.</p><p><strong>Conclusion: </strong>Our study provides a sex-specific clinical risk prediction tool for TR-ROP, which may help preterm infants identify their potential risk profile, reduce unnecessary fundus examination and provide guidance to prevent disease progression.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical Management and Outcomes of Large High Myopic Macular Holes: Global Macular Hole Multicenter Study 3.","authors":"Tianyu Liu, Nassim A Abreu-Arbaje, Joana Andoh, J Fernando Arevalo, Remzi Avci, Bernardo Bach, Maria C Bohorquez, H Culver Boldt, Timothy M Boyce, Ana L Carauni, Matteo M Carla, Viet Q Chau, Hung-Da Chou, Adrienne Coche, Francesco M D'Alterio, Jason Fan, Tina Felfeli, Mariantonia Ferrara, Magno A Ferreira, Carolina Galvá Goriup, Stratos Gotzaridis, Ninel Z Gregori, Ahmed M Habib, Ian C Han, Yi-Ting Hsieh, Makoto Inoue, Kazuaki Kadonosono, Motohiro Kamei, Levent V Karabas, Jacob Keeley, Shohei Kitahata, Sandeep Kumar, Chi-Chun Lai, Bingqian Liu, Lin Lu, Mohamed M Mahgoub, Efrem Mandelcorn, Ahmed Mansour, Carlos Mateo, Ryo Matoba, Yuki Morizane, Christine Morozova, Zofia A Nawrocka, Jerzy Nawrocki, Marcio B Nehemy, Ronaldo Nuesi, Ogugua N Okonkwo, Ecem Onder Tokuc, Sengul Ozdek, Ece Ozdemir Zeydanli, Jong G Park, Barbara Parolini, Fabio Patelli, Seemant Raizada, Revati Rashingkar, Eugen Reifschneider, Flavio A Rezende, Stanislao Rizzo, Mario R Romano, Stephen R Russell, Khalid A Sabti, Teresa Sandinha, Lydia Sauer, Alfonso Savastano, Daraius Shroff, Elliott H Sohn, David H Steel, Peter Szurman, Homayoun Tabandeh, Jonathan Than, Loka Thangamathesvaran, Kotaro Tsuboi, Mei-Chi Tsui, Ana Rita Viana, Hannah Walsh, George A Williams, Tom H Williamson, Chen Xi, Chung-May Yang, Aysegul M Yildiz, Tadashi Yokoi, Yoshihiro Yonekawa, Androniki Zampogianni, Tamer H Mahmoud","doi":"10.1097/IAE.0000000000004871","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004871","url":null,"abstract":"<p><strong>Purpose: </strong>To characterize the surgical management and outcomes of large high myopic macular holes (HMMHs).</p><p><strong>Methods: </strong>Global multicenter retrospective case series of HMMHs with minimum linear diameter (MLD) ≥ 400 μm undergoing surgery between 2013-2023 with follow up ≥ 3 months. The main outcome measure was the HMMH closure rate at postoperative month 3.</p><p><strong>Results: </strong>499 cases of 463 patients from 37 surgeons were included, with mean ± SD age 58.3 ± 12.2 years, 77.0% female, 77.4% primary, 22.6% refractory, and mean ± SD follow-up 18.8 ± 20.2 months. The mean ± SD (range) MLD was 649 ± 280 (400, 2759) µm. Surgery techniques included 127 internal limiting membrane (ILM) peels, 285 ILM flaps, 19 amniotic membrane transplantations (AMT), 36 autologous retinal transplantations (ART), and 32 others. The postoperative month 3 closure rate for all cases was 72.4%. Closure rates significantly decreased with greater CLOSE Study Group size classification for HMMHs treated with ILM peeling or ILM flap (P = 0.006) but not for HMMHs treated with AMT or ART (P > 0.05). Visual acuity (VA) significantly increased from baseline to each follow-up time point among all eyes, with final mean ± SD change in VA of -0.29 (0.55) logMAR (+14.5 ETDRS letters), which did not significantly differ by surgery type.</p><p><strong>Conclusion: </strong>HMMH closure rates are lower than those reported for macular holes in non-highly myopic eyes, but most eyes can still achieve anatomic closure and meaningful VA gains when treated with the appropriate technique.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between thin and thick choroid eyes in central serous chorioretinopathy.","authors":"Sanya Yadav, Nasiq Hasan, Niroj Sahoo, Arman Zarnegar, Jessica Cao, Avery Zhou, Stanley Saju, Charles C Wykoff, Priya Shah, Panisa Singhanetr, Elizabeth Rossin, Lorenzo Ferro Desideri, Felicia Hertkorn, Marion R Munk, Carmen Antia, Luis A Barquet, Min Kim, Stela Vujosevic, Yusuf Ashfaq, Zachary Kroeger, Lorenzo Pili, Lisa Checchin, Maurizio B Parodi, Manjot Gill, Samer Khateb, Michael Zhang, Francisco Rodriguez, Peranut Chotcomwongse, Paisan Ruamviboonsuk, Adrian Fung, Jay Wang, Rahul N Khurana, Luiz H Lima, Lihteh Wu, Jay Chhablani","doi":"10.1097/IAE.0000000000004875","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004875","url":null,"abstract":"<p><strong>Purpose: </strong>While central serous chorioretinopathy (CSCR) is typically associated with pachychoroid, a subset of patients presents with thin choroids. This study aims to compare the clinical features of CSCR in thin versus thick choroid eyes.</p><p><strong>Methods: </strong>In this retrospective multicenter study, patients were categorized by subfoveal choroidal thickness (SFCT) into thin (≤250 µm) and thick (≥400 µm) groups. Multimodal imaging was used to analyze central macular thickness (CMT), SFCT, neurosensory detachment height (NSRD-h), Haller vessel thickness (HVT), and inner choroidal thickness (ICT) at baseline and final visit.</p><p><strong>Results: </strong>Among 355 eyes, 52 (14.6%) had thin and 303 (85.4%) had thick choroids. Thin choroid patients were older (p<0.001) and more often female (38.5% vs. 23.1%,p=0.019). Visual acuity was similar at baseline (0.30 Log Minimum Angle of Resolution (logMAR), Snellen equivalent [20/40]) vs. 0.22 [20/33], p=0.38) and final follow-up (0.18 logMAR [Snellen equivalent [20/30] vs. 0.15 [20/28], p=0.08). CMT decreased in both groups, but SFCT, HVT, and ICT remained stable in the thin group. Spontaneous resolution and recurrence rates were similar; however, choroidal neovascularization (CNV) development was significantly higher in the thin choroid group (p=0.003).</p><p><strong>Conclusions: </strong>Thin-choroid CSCR represents a distinct clinical phenotype with older age, and female predominance. Although CNV occurred more frequently in this group compared to the thick choroid group, multivariate analysis indicates that age may be a key contributor to CNV risk.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation in Dry Age-Related Macular Degeneration: Promising Signal, Familiar Questions.","authors":"Demetrios G Vavvas","doi":"10.1097/IAE.0000000000004823","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004823","url":null,"abstract":"","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":"46 5","pages":"765-767"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147789534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PERSISTENT DIFFUSE PHOTORECEPTOR DISORGANIZATION.","authors":"Miaoling Li, Feng Wen, Lan Mi, Yuying Ji, Yi He, Nanying Liao, Xiongze Zhang","doi":"10.1097/IAE.0000000000004749","DOIUrl":"10.1097/IAE.0000000000004749","url":null,"abstract":"<p><strong>Purpose: </strong>To characterize persistent diffuse photoreceptor disorganization, a newly recognized retinal disorder, and establish diagnostic criteria differentiating it from similar outer retinopathies.</p><p><strong>Methods: </strong>This retrospective observational case series included 14 patients (21 eyes) with subacute vision loss, unremarkable fundus, and persistent diffuse photoreceptor disorganization on optical coherence tomography, from 2020 to 2025. Medical records, multimodal imaging (optical coherence tomography, fundus autofluorescence, fluorescein angiography, indocyanine green angiography), and visual function (electroretinography, visual field) findings were analyzed.</p><p><strong>Results: </strong>Patients (mean age 30.7 years) presented with subacute vision loss [mean best-corrected visual acuity 0.9 LogMAR (20/160), range, 2.0-0.2 (FC-20/32)]. Seven patients (50%) had bilateral involvement. Infectious uveitis and known retinal dystrophy mutations (via whole-exome sequencing) were excluded. Fundus, fundus autofluorescence, and indocyanine green angiography were largely unremarkable. Optical coherence tomography revealed blurred/rough ellipsoid zone and absent interdigitation zone in the posterior pole of all eyes (including fovea in 100% of eyes, periphery in 95.2%). The retinal pigment epithelium layer was preserved. Outer retina thickness was significantly thinner in involved eyes compared with fellow eyes (118.3 vs. 147.6 µ m, P = 0.031). Fundus angiography showed peripheral venous leakage in 75% of eyes. Full-field electroretinography indicated reduced amplitudes (normal latency, scotopic/photopic), and visual fields showed significant defects. Eleven patients received immunosuppressive therapies. Over 17 months, optical coherence tomography abnormalities persisted, outer retina thickness slowly decreased, and visual acuity remained stable with gradual deteriorations in some patients.</p><p><strong>Conclusion: </strong>Persistent diffuse photoreceptor disorganization is characterized by subacute, diffuse, and persistent photoreceptor disorganization with largely unremarkable fundus, distinct from other outer retinopathies. Visual prognosis is generally poor, necessitating further research into pathogenesis and treatment.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"941-949"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETINAL DETACHMENT ASSOCIATED WITH PRESUMED TREMATODE-INDUCED GRANULOMATOUS INTERMEDIATE UVEITIS.","authors":"Salma F Al-Etr, Rawan Hosny, Rana Hussein Amin, Shaymaa H Salah, Hany Hamza, Abdussalam Mohsen Abdullatif","doi":"10.1097/IAE.0000000000004752","DOIUrl":"10.1097/IAE.0000000000004752","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the clinical characteristics and surgical outcomes of retinal detachment (RD) associated with presumed trematode-induced granulomatous intermediate uveitis (PTIGIU).</p><p><strong>Methods: </strong>A review of the medical records of patients diagnosed with RD secondary to PTIGIU over a 3-year period was conducted. Main outcome measures were the type and morphology of RD, final functional and anatomical outcomes.</p><p><strong>Results: </strong>Out of 98 eyes with PTIGIU, 41 eyes (41.8%) were diagnosed with RD secondary to PTIGIU and were operated upon and completed 6-month follow-up period. Mean age was 12.6 years and logMAR corrected distance visual acuity 1.76. All eyes had vitritis of variable grades. Thirty-five eyes (85.4%) had tractional retinal detachment (TRD) and four eyes (9.8%) had combined tractional-rhegmatogenous retinal detachment. According to the extent of retinal detachment, the eyes were grouped into Group 1: 28 eyes, with subtotal peripheral RD, and Group 2: 13 eyes, with total RD or subtotal RD reaching posterior pole. The former group showed better functional and anatomical outcomes ( P = 0.019 and 0.028, respectively). Approximately 80.5% of all eyes showed final anatomical success and visual improvement (median corrected distance visual acuity 0.40, P < 0.001) at the final follow-up.</p><p><strong>Conclusion: </strong>Tractional retinal detachment is a common complication to PTIGIU, and early intervention is essential to avoid devastating ocular complications.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"863-870"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145844155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE \"SCOLEX\" SIGN: A Distinct Hyperreflective Foci on the Wall of Serous Pigment Epithelial Detachments in Central Serous Chorioretinopathy - Micron Report Number Seven.","authors":"Nasiq Hasan, Arman Zarnegar, Elham Sadeghi, Sumit Randhir Singh, Niroj Sahoo, Jessica Cao, Stanley Saju, Avery Zhou, Charles C Wykoff, Samer Khateb, Yusuf Ashfaq, Zachary Kroeger, Jay C Wang, Rahul N Khurana, Lisa Checchin, Lorenzo Pili, Maurizio Battaglia Parodi, Gabriele Piccoli, Stela Vujosevic, Priya Shah, Panisa Singhanetr, Elizabeth Rossin, Carol Villafeurte-Trisoloni, Glenn Yiu, Halit Winter, Manjot K Gill, Lihteh Wu, Jay Chhablani","doi":"10.1097/IAE.0000000000004770","DOIUrl":"10.1097/IAE.0000000000004770","url":null,"abstract":"<p><strong>Purpose: </strong>To describe a novel optical coherence tomography finding called \"scolex sign\" in cases of central serous chorioretinopathy.</p><p><strong>Methods: </strong>This retrospective multicenter study included patients with central serous chorioretinopathy with serous pigment epithelial detachments (PEDs) greater than 100 µ m, with or without subretinal fluid. Eyes showing a distinct hyperreflective focus on the PED wall (scolex sign) were analyzed. An equal number of age-matched controls with PEDs but without the scolex sign were included. Multimodal imaging data were reviewed. A subgroup analysis based on subretinal fluid status was also performed.</p><p><strong>Results: </strong>Of 291 eyes with large serous PEDs, 52 eyes exhibited the \"scolex sign\" and were compared with 52 age-matched controls. Baseline characteristics including sex, systemic comorbidities, best-recorded visual acuity and optical coherence tomography parameters were similar in both the groups. However, eyes with the \"scolex\" sign exhibited a greater number of central PEDs and shorter distance from the foveal center. On follow-up, eyes with the \"scolex\" sign showed a higher rate of PED flattening and subretinal fluid resolution trended to be higher compared with controls.</p><p><strong>Conclusion: </strong>The \"scolex\" sign represents a novel, benign optical coherence tomography feature seen in a subset of central serous chorioretinopathy cases. While not associated with poorer outcomes or adverse sequelae, it may reflect ongoing reparative changes, indicating a resolving stage of the disease.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"871-880"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Intraoperative Use of an Ultra-Widefield Imaging for Retinoblastoma.","authors":"Young Je Choi, Tae Young Kim, Min Kim","doi":"10.1097/IAE.0000000000004676","DOIUrl":"10.1097/IAE.0000000000004676","url":null,"abstract":"","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"e38-e39"},"PeriodicalIF":2.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145071225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}