Retina-The Journal of Retinal and Vitreous Diseases最新文献

Preoperative and early postoperative factors associated with visual outcome after macular-off retinal detachment surgery.

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-22 DOI: 10.1097/IAE.0000000000004416

Yuan Zhao, Yan Sheng

{"title":"Preoperative and early postoperative factors associated with visual outcome after macular-off retinal detachment surgery.","authors":"Yuan Zhao, Yan Sheng","doi":"10.1097/IAE.0000000000004416","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004416","url":null,"abstract":"Purpose: To evaluate preoperative and early postoperative factors associated with changes in visual acuity in macula-off rhegmatogenous retinal detachment (RRD) patients.Methods: A retrospective review of 59 eyes from 59 patients who underwent pars plana vitrectomy (PPV) and silicone oil (SiO) tamponade for macula-off RRD. Preoperative and early postoperative characteristics were analyzed using the classification and regression tree (CART) analysis.Results: The baseline preoperative BCVA improved from 1.67 ± 0.97 logMAR to 0.21 ± 0.22 logMAR at final visit. Central foveal thickness (CFT) and BCVA showed significant increases from 1 week post-surgery onward. Mean CFT significantly increased from 136.97 ± 40.17 μm to 192.54 ± 34.09 μm (p < 0.001). The percentage of eyes with integrated external limiting membrane (ELM) and ellipsoid zone (EZ) was progressively increased from 45.76% and 10.17% to 98.31% and 71.19%, respectively (p < 0.001). BCVA at 1week after surgery, ELM integrity, preoperative intraretinal cysts, and macula-off duration were significantly associated with final visual recovery after surgery.Conclusion: The first week postoperative BCVA is the most powerful predictor for final BCVA. ELM integrity, intraretinal cysts, and macula-off duration are also significantly associated with final visual recovery.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Heterogeneous Presentations of De Novo and Recurrent Ocular Inflammation following COVID-19 Vaccination: A Multi-Center Report and a Review of the Literature.

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-17 DOI: 10.1097/IAE.0000000000004413

Sruthi Arepalli, Laura Kopplin, Edmund Tsui, Daniel Brill, Lucia Sobrin, George Papaliodis, Dana Darwish, Veena Raiji, Priya Janardhana, Parisa Emami-Naeini, Lish Nore, Meredith Parker, Akshay S Thomas

{"title":"The Heterogeneous Presentations of De Novo and Recurrent Ocular Inflammation following COVID-19 Vaccination: A Multi-Center Report and a Review of the Literature.","authors":"Sruthi Arepalli, Laura Kopplin, Edmund Tsui, Daniel Brill, Lucia Sobrin, George Papaliodis, Dana Darwish, Veena Raiji, Priya Janardhana, Parisa Emami-Naeini, Lish Nore, Meredith Parker, Akshay S Thomas","doi":"10.1097/IAE.0000000000004413","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004413","url":null,"abstract":"Purpose: To describe the patterns of ocular inflammation following COVID-19 vaccination, assess underlying commonalities and understand outcomes.Methods: Retrospective, multicenter cohort study, conducted between 2020 and 2021. Patients with no previous uveitis history (de novo) or a known uveitis history (recurrent) who developed ocular inflammation within 42 days of COVID-19 vaccination were identified. Characteristics of the uveitis, treatment approaches and clinical outcomes were assessed.Results: Fifty-five eyes of 39 patients with ocular inflammation temporally related to vaccination were identified. Twenty-two patients (36 eyes) were de novo, while 17 (19 eyes) were recurrent. Anterior uveitis was most common. HLA-B27 positivity was found in 6 (27.2%) de novo patients, and 5 (29.4%) recurrent patients. Most patients required only observation, topical or systemic corticosteroids. Amongst vaccinated patients, 12.3% of new uveitis referrals during the study period were related to COVID-19 vaccination. Among patients with a history of quiescent uveitis, only 0.85% experienced a flare following vaccination.Conclusion: The majority of inflammation thought to be secondary to COVID-19 vaccination achieved quiescence with observation or steroids, and the overall incidence is low. Anterior uveitis was the most common. HLA-B27 positivity occurred at a higher rate than reported in the baseline population.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Generative deep learning approach to predict posttreatment optical coherence tomography images of age-related macular degeneration after 12 months.

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-17 DOI: 10.1097/IAE.0000000000004409

Hyungwoo Lee, Najung Kim, Na Hee Kim, Hyewon Chung, Hyung Chan Kim

{"title":"Generative deep learning approach to predict posttreatment optical coherence tomography images of age-related macular degeneration after 12 months.","authors":"Hyungwoo Lee, Najung Kim, Na Hee Kim, Hyewon Chung, Hyung Chan Kim","doi":"10.1097/IAE.0000000000004409","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004409","url":null,"abstract":"Purpose: Predicting long-term anatomical responses in neovascular age-related macular degeneration (nAMD) patients is critical for patient-specific management. This study validates a generative deep learning (DL) model to predict 12-month posttreatment optical coherence tomography (OCT) images and evaluates the impact of incorporating clinical data on predictive performance.Methods: A total of 533 eyes from 513 treatment-naïve nAMD patients were analyzed. A conditional generative adversarial network (cGAN) served as the baseline model, generating 12-month OCT images using pretreatment OCT, fluorescein angiography (FA), and indocyanine green angiography (ICGA). We then sequentially added OCT after three loading doses, baseline visual acuity (VA), treatment regimen (pro re nata or treat-and-extend), drug type, and switching events. The generated and patient OCT images were compared for intraretinal fluid, subretinal fluid, pigment epithelial detachment, and subretinal hyperreflective material, both qualitatively and quantitatively.Results: The baseline model achieved acceptable accuracy for four macular fluid compartments (range 0.74-0.96). Incorporating OCT after loading doses and other clinical parameters improved accuracy (range 0.91-0.98). With all the clinical inputs, the model achieved 92% accuracy in distinguishing wet macular status from dry macular status. The segmented fluid compartments in the generated images correlated positively with those in the patient images.Conclusion: Integrating clinical and treatment data, particularly OCT data after loading doses, significantly enhanced the 12-month predictive performance of cGANs. This approach can help clinicians anticipate anatomical outcomes and guide personalized, long-term nAMD treatment strategies.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Drusen volume as clincial outcome measure in subjects with malattia leventinese.

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-17 DOI: 10.1097/IAE.0000000000004407

Clara Ehrenzeller, Giuseppe Cancian, Arianna Paris, Gabriela Grimaldi, Maximilian Pfau, Moreno Menghini

{"title":"Drusen volume as clincial outcome measure in subjects with malattia leventinese.","authors":"Clara Ehrenzeller, Giuseppe Cancian, Arianna Paris, Gabriela Grimaldi, Maximilian Pfau, Moreno Menghini","doi":"10.1097/IAE.0000000000004407","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004407","url":null,"abstract":"Purpose: To assess if drusen volume can serve as structural clinical outcome marker in Malattia Leventinese (ML), and to evaluate whether cones or rods are more affected by its progression, using multimodal imaging and mesopic and two-color scotopic microperimetry.Methods: This was a prospective monocentric cross-sectional cohort study of participants with genetically confirmed ML. Participants were classified according to morphology. Mean drusen volume, calculated from SD-OCT, was compared to microperimetry parameters (mesopic retinal sensitivity, scotopic red and cyan function, difference between scotopic cyan-red function).Results: Fourteen participants (28 eyes) were enrolled. Mean drusen volume increased (bilaterally P=0.028) and mesopic retinal sensitivity decreased with later stage (OD: P=0.028; OS: P=0.050). Scotopic microperimetry showed that scotopic cyan function was lower than scotopic red function in moderate stage. Scotopic red function decreased in severe stage. Mean drusen volume correlated to mesopic retinal sensitivity (OD: P<0.001; OS: P=0.007).Conclusion: Retinal sensitivity diminishes with ML progression. Rod function declines prior to cone function, while at late stages, cone loss predominates. Drusen accumulation, initially speckled around the macula and optic disc and confluent with disease progression, correlates well with visual function loss and impaired quality of life. Thus, therapeutically reducing drusen accumulation could be efficacious.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined Pars Plana Vitrectomy and Novel Scleral Fixation of the Light Adjustable Lens.

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-17 DOI: 10.1097/IAE.0000000000004410

Nhuong-Sao Ton, Matthew Kruger, Murtaza K Adam

{"title":"Combined Pars Plana Vitrectomy and Novel Scleral Fixation of the Light Adjustable Lens.","authors":"Nhuong-Sao Ton, Matthew Kruger, Murtaza K Adam","doi":"10.1097/IAE.0000000000004410","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004410","url":null,"abstract":"Purpose: The light adjustable lens (LAL) (RxSight, Aliso Viejo, CA) is a premium intraocular lens that allows for correction of residual refractive error and astigmatism following implantation. Herein, we describe the surgical approach and evaluate the visual outcomes of patients following scleral fixation of the LAL.Methods: Retrospective, single-surgeon surgical case series of 3 patients (3 eyes) with intraocular lens complications, who underwent combined pars plana vitrectomy and sutureless needle assisted intrascleral haptic fixation of the LAL between April 2022, to August 2023.Results: A total of 3 patients (73.3 ± 4.4 years) underwent off-label application of sutureless intrascleral haptic fixation of the LAL. Indications for surgery included pseudophacodonesis (N=1), dislocated subluxed IOL with secondary vitreous hemorrhage (N=1), and multifocal IOL intolerance (N=1). Preoperative average visual acuity of 0.2 ± 0.1 (20/30) LogMAR improved to 0.03 ± 0.03 LogMAR (20/20) at 1 month follow-up after LAL ultraviolet light treatments. Preoperative sphere of +0.25 ± 0.9 improved to +0.0 ± 0.0 and preoperative cylinder of +0.4 ± 0.4 improved to +0.0 ± 0.0 postoperatively. No surgical complications were noted.Conclusion: Scleral fixation of the LAL is a viable option for eyes without capsular support to maximize postoperative uncorrected visual acuity outcomes.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vitreous cavity lavage with a bended-needle system for postoperative vitreous cavity hemorrhage.

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-17 DOI: 10.1097/IAE.0000000000004403

Mingyue Luo, Chan Wu, Youxin Chen, Shiqun Lin, Yan Zhou, Xingyu Xiao, Rongping Dai

{"title":"Vitreous cavity lavage with a bended-needle system for postoperative vitreous cavity hemorrhage.","authors":"Mingyue Luo, Chan Wu, Youxin Chen, Shiqun Lin, Yan Zhou, Xingyu Xiao, Rongping Dai","doi":"10.1097/IAE.0000000000004403","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004403","url":null,"abstract":"Purpose: To present a novel bended-needle drainage system in vitreous cavity lavage (VCL) for postoperative vitreous cavity hemorrhage (POVCH).Methods: This retrospective case series include all patients with POVCH who received VCL with the bended-needle drainage system at ophthalmology department of Peking Union Medical College Hospital from January 2022 to May 2024. Patients adopted a supine position that allows preparation and draping. Balanced salt solution was injected with a 30 Ga needle. One bended 25 Ga needle was used to drain the blood. Primary outcomes include the visual acuity and short-term post-procedure complications. Secondary outcomes include preoperative and postoperative intraocular pressure (IOP) and long-term complications.Results: Three patients with POVCH received the procedure, with two cases of proliferative diabetic retinopathy and one case of primary central nervous system lymphoma. All patients recovered well after the procedure with minimal complications. Long-term prognosis largely depends on the primary retinal conditions.Conclusions: In conclusions, VCL with the bended-needle system is safe and effective to manage POVCH with an outpatient surgery, which potentially benefits patients with similar conditions.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simplified Technique for Correcting Intraocular Lens Decentration in Scleral-Sutured Fixation Surgery.

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-17 DOI: 10.1097/IAE.0000000000004401

Jiemei Shi, Yuan Zong, Kaicheng Wu, Chunhui Jiang

{"title":"Simplified Technique for Correcting Intraocular Lens Decentration in Scleral-Sutured Fixation Surgery.","authors":"Jiemei Shi, Yuan Zong, Kaicheng Wu, Chunhui Jiang","doi":"10.1097/IAE.0000000000004401","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004401","url":null,"abstract":"Purpose: To describe a simplified technique for correcting intraocular lens (IOL) decentration during scleral-sutured IOL fixation surgery.Methods: During surgery, Purkinje images were utilized to assess IOL positioning. A straightforward IOL decentration adjustment technique was employed when necessary. Patients in whom IOL position were corrected and who were followed up for at least three months after surgery were included in the study.Results: From June 2023 to February 2024, six patients with noticeable IOL decentration were successfully treated using this technique. After a mean follow-up of 3.17 ± 0.37 months, there was a significant change in spherical equivalent (preoperative +10.55 ± 2.48 D, postoperative -1.58 ± 2.19 D). While the best-corrected visual acuity, refractive cylinder, intraocular pressure, and corneal endothelium density remained unchanged. Importantly, the IOL was well-centered in all six patients, with average horizontal and vertical IOL decentration of 0.21 ± 0.16 mm and 0.20 ± 0.15 mm, respectively.Conclusion: This simple IOL decentration correction technique demonstrated favorable results and may enhance IOL positioning in scleral fixation procedures.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinal Vessels Whitening in Retinitis Pigmentosa.

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-17 DOI: 10.1097/IAE.0000000000004405

Shaden H Yassin, Naomi E Wagner, Fritz Gerald P Kalaw, Paripoorna Sharma, Juan D Arias, Melanie Tran, Ines Nagel, Evan Walker, Shyamanga Borooah

{"title":"Retinal Vessels Whitening in Retinitis Pigmentosa.","authors":"Shaden H Yassin, Naomi E Wagner, Fritz Gerald P Kalaw, Paripoorna Sharma, Juan D Arias, Melanie Tran, Ines Nagel, Evan Walker, Shyamanga Borooah","doi":"10.1097/IAE.0000000000004405","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004405","url":null,"abstract":"Purpose: To characterize retinal vessel whitening (RVW) in Retinitis Pigmentosa (RP).Methods: Single-center cross-sectional study. Review of clinical notes of clinically confirmed RP patients was performed followed by grading ultra-widefield imaging. Data collected included Best corrected visual acuity (BCVA), presence or absence and location of RVW and were correlated with disease.Results: In total, 120 RP patients' charts were reviewed. Of these, 116 patients (232 eyes) were included in the final analysis with a mean age of 43.2 (39.8, 46.6) and a 1:1 male to female ratio. RVW was seen in either eye of 44 (38%) subjects, most frequently in the inferotemporal quadrant (p< 0.001). Total retinal thickness within the ETDRS area was significantly less in eyes with RVW (p<0.001), a mean difference of 151.7 µm. Both the inner and outer retina were thinner in the RVW group (p<0.001). There was also a significant association (p<0.04) between the number of quadrants of the retina affected by RVW and the reduction in retinal thickness.Conclusion: RVW is a common finding in RP, suggesting that it should be considered as a phenotypic feature of RP. RVW is also associated with structural changes to the central macula indicating its potential use as a marker of retinal disease severity.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of leakage sites in central serous chorioretinopathy using optical coherence tomography and the assessment of the characteristics of the biomarkers.

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-17 DOI: 10.1097/IAE.0000000000004404

Ryoh Funatsu, Hiroto Terasaki, Naohisa Mihara, Shozo Sonoda, Hideki Shiihara, Shoki Miyake, Hiroki Imatsuji, Taiji Sakamoto

{"title":"Identification of leakage sites in central serous chorioretinopathy using optical coherence tomography and the assessment of the characteristics of the biomarkers.","authors":"Ryoh Funatsu, Hiroto Terasaki, Naohisa Mihara, Shozo Sonoda, Hideki Shiihara, Shoki Miyake, Hiroki Imatsuji, Taiji Sakamoto","doi":"10.1097/IAE.0000000000004404","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004404","url":null,"abstract":"Purpose: To identify optical coherence tomography (OCT)-based imaging biomarkers that can localize focal leakage points without fluorescein angiography in central serous chorioretinopathy (CSC).Methods: This retrospective case-control study analyzed 119 consecutive patients (123 eyes) with CSC between April 2018 and February 2024, comprising 66 eyes with focal-leakage type and 57 eyes with diffuse-leakage type. We assessed leakage sites using OCT, and the proportions of OCT findings were compared between focal- and diffuse-leakage types.Results: Hyporeflective lucency signs were observed in 27 eyes (40.9%) with focal-type CSC, while no such signs were detected in diffuse-type CSC cases (0.0%; P < 0.001). In focal-type CSC, these signs were exclusively localized to leakage points, with no occurrence in other areas within serous retinal detachment. Microrip of retinal pigment epithelium and subretinal hyperreflective material were identified in 23 (34.8%) and 47 (71.2%) eyes with focal-type CSC, respectively, and also in eyes with diffuse-type CSC (5.3% and 19.3%, respectively; P < 0.001 for both comparisons).Conclusions: Only the hyporeflective lucency sign is present exclusively in focal leakage points of fluorescein angiography. Our findings suggested that the hyporeflective lucency sign may serve as a potential therapeutic target in CSC.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adverse effect of Henle fiber layer hemorrhage due to retinal arterial macroaneurysm rupture on retinal sensitivity. 视网膜大动脉瘤破裂致亨勒纤维层出血对视网膜敏感性的影响。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-01-15 DOI: 10.1097/IAE.0000000000004411

Riku Akatsuka, Shuhei Kimura, Shinichiro Doi, Mio Morizane Hosokawa, Yusuke Shiode, Ryo Matoba, Tetsuro Morita, Yuki Morizane

{"title":"Adverse effect of Henle fiber layer hemorrhage due to retinal arterial macroaneurysm rupture on retinal sensitivity.","authors":"Riku Akatsuka, Shuhei Kimura, Shinichiro Doi, Mio Morizane Hosokawa, Yusuke Shiode, Ryo Matoba, Tetsuro Morita, Yuki Morizane","doi":"10.1097/IAE.0000000000004411","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004411","url":null,"abstract":"Purpose: To investigate the effect of Henle fiber layer hemorrhage (HFLh) on retinal sensitivity (RS) before and after displacement of the submacular hemorrhage (SMH) caused by retinal arterial macroaneurysm (RAM) rupture.Methods: This retrospective study included 31 eyes undergoing vitrectomy for SMH. Eyes were grouped based on the presence or absence of HFLh (HFLh [+/-] group). RS was assessed in the fovea and in the area of the HFLh present preoperatively.Results: The HFLh (+) and HFLh (-) groups had 21 and 10 eyes, respectively. Both groups showed improved postoperative foveal RS (both P < 0.05), which was significantly higher in the HFLh (-) group (P = 0.02). In the HFLh (+) group, RS was significantly lower in the affected eye when compared to the fellow eye (P < 0.01), whereas in the HFLh (-) group, no significant difference was noted between both eyes (P = 0.58). Despite the significant improvement in the postoperative RS in areas with preoperative HFLh (P < 0.001), it remained lower than the RS of the fellow eye (P < 0.05).Conclusion: SMH displacement improved RS regardless of HFLh presence, although the degree of improvement was limited in the presence of HFLh.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0