Revakinagene tarretcel植入的最新外科技术。

IF 2.1 2区医学 Q2 OPHTHALMOLOGY

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-10-01 DOI:10.1097/IAE.0000000000004694

Gail M Teagle, Avery W Zhou, Thomas M Aaberg, Charles C Wykoff

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引用次数: 0

摘要

目的：介绍一种新的外科植入术技术。方法：对手术技术进行描述，并附有辅助录像。结果：revakinagene tarretcel手术植入安全，无不良反应。将巩膜囊置入玻璃体腔内，用双臂9-0聚丙烯缝线将相关的固定环适当地固定在巩膜上，用9-0尼龙缝线关闭巩膜切开线，关闭结膜以确保缝合线和插入部位得到适当的覆盖。结论：所描述的手术植入技术是从相关的2期和3期试验中学习到的，并实施以最大限度地提高胶囊长期稳定性的可能性，并最大限度地减少不良事件的风险，包括器械挤压。

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Updated Surgical Technique for Implantation of Revakinagene Taroretcel.

Purpose: Present an updated technique for surgical implantation of revakinagene taroretcel.

Methods: The surgical technique is described with supplemental video included.

Results: Surgical implantation of revakinagene taroretcel was safely performed without adverse events. The capsule was positioned into the vitreous cavity, the associated fixation loop was appropriately secured to the sclera using a double-armed 9-0 polypropylene suture, the sclerotomy was closed with 9-0 nylon sutures, and the conjunctiva was closed to ensure proper coverage of the sutures and insertion site.

Conclusion: The described surgical implantation technique was developed using learnings from the associated phase 2 and 3 trials and implemented to maximize the likelihood of long-term capsule stability and minimize the risk of adverse events including device extrusion.

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来源期刊

Retina-The Journal of Retinal and Vitreous Diseases 医学-眼科学

CiteScore

5.70

自引率

9.10%

发文量

554

审稿时长

3-6 weeks

期刊介绍： RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.