OUTER RETINAL LAYER DETERIORATION PATTERNS IN EYES WITH DIABETIC SEROUS MACULAR DETACHMENT.

IF 2.1 2区医学 Q2 OPHTHALMOLOGY

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-10-07 DOI:10.1097/IAE.0000000000004698

Furkan Kirik, M Giray Ersoz, Furkan Atalay, Ersin Akbulut, Mehmet Kucuk, Arif Koytak, Hakan Ozdemir

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引用次数: 0

Abstract

Purpose: To classify the outer retinal layer (ORL) deterioration patterns in eyes with diabetic serous macular detachment (SMD), and to determine their impact on visual and anatomical prognosis.

Methods: In this retrospective case series, optical coherence tomography images of patients with diabetic macular edema between January 2015 and June 2024 were reviewed. Eyes exhibiting SMD were evaluated for ORL integrity, and five different ORL deterioration patterns were identified according to their structural characteristics: DIFFUSE, PATCH, WEDGE, FISTULA, and SMD-DROL. The relationship of these patterns with best-corrected visual acuity (BCVA), and post-treatment external limiting membrane (ELM) and ellipsoid zone (EZ) status was analyzed with regression models.

Results: A total of 1018 eyes of 592 patients were reviewed, and 168 eyes of 131 patients exhibited at least one ORL deterioration pattern. WEDGE was the most common pattern (31.75%), while DIFFUSE was the least detected (5.29%). WEDGE was associated with better BCVA, as well as with a decreased risk of alterations in the ELM/EZ (p<0.001). ELM/EZ alterations were observed in all eyes with the DIFFUSE, and post-treatment ELM alteration width was associated with poorer visual outcome (p<0.05).

Conclusion: Diabetic SMD may present various ORL deterioration patterns associated with heterogeneous clinical and anatomical outcomes.

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糖尿病性浆液性黄斑脱离的视网膜外层退化模式。

目的：对糖尿病性浆液性黄斑脱离（SMD）的视网膜外层（ORL）恶化模式进行分类，并探讨其对视力和解剖预后的影响。方法：回顾性分析2015年1月至2024年6月期间糖尿病性黄斑水肿患者的光学相干断层扫描图像。对出现SMD的眼睛进行ORL完整性评估，并根据其结构特征确定了五种不同的ORL恶化模式：弥漫性、斑块性、楔形、瘘管性和SMD- drol。用回归模型分析这些模式与最佳矫正视力（BCVA）、治疗后外限制膜（ELM）和椭球带（EZ）状态的关系。结果：592例患者共1018只眼，131例患者168只眼出现至少一种ORL恶化模式。楔形病变最常见（31.75%），弥漫性病变最少（5.29%）。WEDGE与更好的BCVA以及ELM/EZ改变的风险降低相关(结论：糖尿病性SMD可能呈现与异质性临床和解剖结果相关的各种ORL恶化模式。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Retina-The Journal of Retinal and Vitreous Diseases 医学-眼科学

CiteScore

5.70

自引率

9.10%

发文量

554

审稿时长

3-6 weeks

期刊介绍： RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.