Retina-The Journal of Retinal and Vitreous Diseases最新文献_第10页

Letter to the Editor concerning the manuscript entitled "Outcomes of Descemet Membrane Epiretinal Graft for Refractory Macular Hole Closure". 致编辑关于题为“视网膜前膜移植术治疗难治性黄斑孔闭合”的稿件的信。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-08 DOI: 10.1097/IAE.0000000000004598

Nicolas Abihaidar, Mathilde Kaspi, Nacim Bouheraoua, Vincent Borderie, Thibaud Garcin

引用次数: 0

Factors influencing the number of anti-VEGF injections in myopic choroidal neovascularization: a multicenter study. 影响近视脉络膜新生血管中抗vegf注射次数的因素：一项多中心研究。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-08 DOI: 10.1097/IAE.0000000000004605

Niccolò Castellino, Giovanni Rubegni, Max Brinkmann, Tom Müller, Giacomo Boscia, Pasquale Viggiano, Maria Oliva Grassi, Silvia Ferraro, Andrea Russo, Francesco Boscia, Teresio Avitabile, Antonio Longo, Mario Damiano Toro

{"title":"Factors influencing the number of anti-VEGF injections in myopic choroidal neovascularization: a multicenter study.","authors":"Niccolò Castellino, Giovanni Rubegni, Max Brinkmann, Tom Müller, Giacomo Boscia, Pasquale Viggiano, Maria Oliva Grassi, Silvia Ferraro, Andrea Russo, Francesco Boscia, Teresio Avitabile, Antonio Longo, Mario Damiano Toro","doi":"10.1097/IAE.0000000000004605","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004605","url":null,"abstract":"Purpose: To investigate the factors influencing the number of injections in myopic choroidal neovascularization (mCNV) as well as to identify the clinical features of patients who require a limited number of injections to inactive mCNV.Methods: This retrospective study included 86 eyes (86 patients) affected by treatment-naïve mCNV who were treated with pro re nata anti-VEGF injections with a follow-up at 12 months. Patients underwent complete ophthalmic visits, Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA) both at baseline and at 12 months.Results: Overall, the mean age of the study population was 62±14 years. The mean number of intravitreal injections administered in the 12-month study period was 4.28±2.17. The multivariate analysis showed an association of baseline Central Macular Thickness (CMT) and Best-Corrected Visual Acuity (BCVA) (p=0.02 and 0.036, respectively) while the final factors related to injections number were subretinal fibrosis and final BCVA (p<0.001 and p=0.022, respectively). Patients who required 1 or 2 injections showed significant clinical differences in OCT, OCTA and clinical parameters in comparison to patients who require more injections.Conclusion: Baseline poorer BCVA and baseline higher CMT are significantly associated with the need of more injections to stabilize the clinical picture in eyes affected by mCNV.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic and Therapeutic Challenges - Patient with Recalcitrant Uveitis. 诊断和治疗的挑战-顽固性葡萄膜炎患者。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-08 DOI: 10.1097/IAE.0000000000004597

Yuxi Zhang, Qian Li, Feng Zhang, Xiangyu Shi, Xiaoyan Peng

引用次数: 0

AI-Enhanced OCT Analysis for Detecting ILM Removal in ERM Surgery. 人工智能增强的OCT分析在ERM手术中检测ILM去除。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-08 DOI: 10.1097/IAE.0000000000004606

Nehal Nailesh Mehta, An D Le, Ines D Nagel, Akshay Agnihotri, Anna Heinke, Lingyun Cheng, Dirk-Uwe Bartsch, Melanie Tran, Nguyen Truong, An Cheolhong, William R Freeman

{"title":"AI-Enhanced OCT Analysis for Detecting ILM Removal in ERM Surgery.","authors":"Nehal Nailesh Mehta, An D Le, Ines D Nagel, Akshay Agnihotri, Anna Heinke, Lingyun Cheng, Dirk-Uwe Bartsch, Melanie Tran, Nguyen Truong, An Cheolhong, William R Freeman","doi":"10.1097/IAE.0000000000004606","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004606","url":null,"abstract":"Purpose: This study evaluates how accurately humans and artificial intelligence (AI) can identify the type of surgery performed for epiretinal membrane (ERM) removal by analyzing postoperative optical coherence tomography (OCT) scans.Methods: A retrospective analysis at the University of California San Diego included 250 eyes from 239 patients who underwent vitrectomy for idiopathic ERM between January 2013 and October 2024. Eyes were categorized into two groups: one with both the internal limiting membrane (ILM) and ERM removed using indocyanine green (ICG) staining, and another with only ERM removal, guided by triamcinolone. Postoperative OCT scans were labeled as either ERM-only or ILM+ERM peel based on surgical notes. Both the human grader and AI model were trained on 200 labeled OCT scans and tested on 50 masked OCT scans to classify the surgery type.Results: Accuracy of the human grader in identifying the surgical technique was 50%, while the AI models demonstrated significantly higher accuracy. The ResNet18 model achieved 61±3%, while UwU-OrthLatt with DB4 initialization and UwU-PR-Relax with Symlet4 initialization reached 70±5% and 69±3%, respectively.Conclusions: AI outperformed human grading in detecting ILM removal from OCT scans, demonstrating AI's potential in improving ophthalmic imaging for clinical use.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current Status and Determinants of Postoperative Visual Function-Related Quality of Life in Retinal Detachment Patients: A Multivariate Analysis. 视网膜脱离患者术后视觉功能相关生活质量的现状和决定因素：多因素分析。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-07 DOI: 10.1097/IAE.0000000000004589

Xiaojun Zhao, Chenjing Fan, Huifang Chen

{"title":"Current Status and Determinants of Postoperative Visual Function-Related Quality of Life in Retinal Detachment Patients: A Multivariate Analysis.","authors":"Xiaojun Zhao, Chenjing Fan, Huifang Chen","doi":"10.1097/IAE.0000000000004589","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004589","url":null,"abstract":"Purpose: Retinal detachment is a sight-threatening condition that requires surgical intervention. However, conventional surgical procedures for retinal detachment repair often adversely impact patients' quality of life. Identifying key factors affecting quality of life is crucial for designing effective clinical interventions.Methods: This study included 120 patients who underwent retinal detachment repair at our hospital between January 2020 and July 2021. Postoperative quality of life was assessed using the National Eye Institute Visual Function Questionnaire (NEI-VFQ-25). Univariate and multiple linear regression analyses were conducted to evaluate factors influencing quality of life.Results: The mean NEI-VFQ-25 score was 74.82±8.44. The lowest scores were observed in the dimensions of overall vision, distance activties, and mental health. Univariate analysis revealed that gender, education level, occupation, monthly income, preoperative waiting time, surgical method, and visual acuity of both the operative and contralateral eyes significantly affected postoperative quality of life (P<0.05). Multivariate regression analysis identified gender, education level, economic status, preoperative waiting time, surgical method, and visual acuity of both the operative and contralateral eyes as independent influencing factors (P<0.05).Conclusion: Postoperative vision-related quality of life among retinal detachment patients remains suboptimal. Significant influencing factors include gender, education level, economic status, surgical method, preoperative waiting time, and visual acuity of the operative and contralateral eyes. Targeted interventions addressing these factors could improve patient outcomes.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Regional Variability in Choroidal Vascularity Index and Association with Intervortex Anastomoses in Polypoidal Choroidal Vasculopathy. 息肉样脉络膜血管病变脉络膜血管指数的区域变异及其与漩涡间吻合的关系。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-07 DOI: 10.1097/IAE.0000000000004590

Yu Jeat Chong, Kelvin Yi Chong Teo, Noa Gilead, Masahiro Akiba, Chui Ming Gemmy Cheung

{"title":"Regional Variability in Choroidal Vascularity Index and Association with Intervortex Anastomoses in Polypoidal Choroidal Vasculopathy.","authors":"Yu Jeat Chong, Kelvin Yi Chong Teo, Noa Gilead, Masahiro Akiba, Chui Ming Gemmy Cheung","doi":"10.1097/IAE.0000000000004590","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004590","url":null,"abstract":"Purpose: To evaluate the regional variation in choroidal vascularity index (CVI) in polypoidal choroidal vasculopathy (PCV) and association with intervortex anastomosis (IA).Methods: Fifty-one eyes with PCV were included. Volumetric optical coherence tomography (OCT) scan was acquired on a 6 X 6mm2 macula area and divided into 36 individual squares. CVI was calculated using an automated algorithm. The different regions were: central, superior-temporal (ST), inferior-temporal (IT), superior-nasal (SN), inferior-nasal (IN). IA was detected using en-face OCT.Results: The mean (SD) CVI of the whole macula was 61.01% (1.46), similar to all the other regions (pairwise comparison, all P >0.05). CVI range was 48.75%-69.48%. The mean (SD) coefficient of variation (CoV) was 1.9% (1.3).IA was present 64.7% of eyes. Eyes with IA had higher mean (SD) whole macula CVI (61.39% (1.43) versus 60.30% (1.26), P=0.01) and SFCT (265.8 µm (103.4) versus 190.1 µm (78.3), P =0.01) compared those without; and a lower mean (SD) CVI range (6.08% (2.38) versus 8.27% (4.13), P =0.04). Although the mean CVI CoV was lower in eyes with IA, 1.6% (0.8) versus 2.4% (1.8), this was not statistically significant, P=0.14.Conclusion: Regional CVI variability may precede the formation of IA supporting the hypothesis that IA could be a compensatory mechanism for choroidal congestion.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dissemination of Uveal Melanoma After Diagnostic Biopsy With 23-Gauge Vitrector. 23号玻璃体诊断活检后葡萄膜黑色素瘤的播散。

IF 2.1 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-07 DOI: 10.1097/IAE.0000000000004573

Hung-Da Chou, Rodrigo Anguita, Caroline Thaung, Lamis Alharby, Guy S Negretti, Lyndon da Cruz, Mandeep S Sagoo

{"title":"Dissemination of Uveal Melanoma After Diagnostic Biopsy With 23-Gauge Vitrector.","authors":"Hung-Da Chou, Rodrigo Anguita, Caroline Thaung, Lamis Alharby, Guy S Negretti, Lyndon da Cruz, Mandeep S Sagoo","doi":"10.1097/IAE.0000000000004573","DOIUrl":"10.1097/IAE.0000000000004573","url":null,"abstract":"Purpose: To report a case with tumor dissemination after diagnostic choroidal biopsy.Methods: Multimodal imaging and histopathology correlation.Results: A 64-year-old male presented with an atypical uveal mass and underwent a diagnostic transretinal 23-gauge vitrector biopsy to diagnose melanoma. Post-operative course was complicated by prolonged vitreous hemorrhage which required vitrectomy, delaying proton beam treatment by two months. One year after the biopsy, the tumor cells had disseminated to the retina, optic nerve, iris, iridocorneal angle, and extraocularly via the vitrectomy port. The patient died from metastatic melanoma one year later. To the best of our knowledge, there are 10 prior cases with biopsy-related tumor seeding in the literature, with risk features including multiple vitreous surgeries, a long interval between biopsy and treatment, and high-risk melanoma cytogenetics. Severe vitreous hemorrhage following biopsy further postpone treatments or warrant vitrectomy, both increasing the risk of tumor spread.Conclusions: Biopsy of choroidal melanoma, especially when complicated by severe vitreous hemorrhage, can lead to dissemination of the malignant tumor.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366731/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Outcomes of Scleral Buckling in Elderly Patients with Rhegmatogenous Retinal Detachment: A Retrospective Cohort Study. 老年孔源性视网膜脱离患者巩膜屈曲的临床结果：一项回顾性队列研究。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-07 DOI: 10.1097/IAE.0000000000004594

Xinlei Zhu, Mengying Xu, Nan Chen, Lingxiao Lun, Lei Wan

{"title":"Clinical Outcomes of Scleral Buckling in Elderly Patients with Rhegmatogenous Retinal Detachment: A Retrospective Cohort Study.","authors":"Xinlei Zhu, Mengying Xu, Nan Chen, Lingxiao Lun, Lei Wan","doi":"10.1097/IAE.0000000000004594","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004594","url":null,"abstract":"Purpose: To evaluate the outcomes of scleral buckling in elderly patients with rhegmatogenous retinal detachment (RRD) and identify independent predictors of postoperative visual outcomes.Methods: This retrospective study included 290 eyes from 278 patients who underwent scleral buckling between 2018 and 2024. Patients aged ≥60 years were defined as the elderly group; those ≤30 years served as controls. Clinical parameters and surgical outcomes were analyzed. Logistic regression was performed in the elderly group to identify predictors of final visual acuity.Results: In elderly patients, scleral buckling achieved a single-surgery anatomical success (SSAS) rate of 98.23%, with 92.03% showing stable or improved vision. Compared to younger patients, the elderly group had lower rates of postoperative intraocular pressure elevation (7.08% vs. 25.99%, P<0.001) and subretinal hemorrhage (2.65% vs. 9.60%, P=0.023), but a higher prevalence of posterior vitreous detachment (PVD; 71.7% vs. 17.5%, P<0.001), which was associated with break location and RRD quadrant (P<0.001). In the elderly group, multivariate analysis identified baseline visual acuity, macula-on status, and grade C proliferative vitreoretinopathy as independent predictors of visual outcomes (P<0.05).Conclusion: Scleral buckling remains a safe and effective option for selected elderly RRD patients. Proper case selection and timely surgery are essential for achieving favorable outcomes in the vitrectomy era.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Re: Stanga PE, Reinstein DZ, Valentin Bravo FJ, et al. THERAPEUTIC REFRACTIVE VITRECTOMY (TRV) FOR THE MANAGEMENT OF VITREOUS FLOATERS AND OPACITIES (VFO) ASSESSED BY THE STANDARDIZED AND KINETIC ANATOMICAL AND FUNCTIONAL TESTING OF VITREOUS FLOATERS AND OPACITIES (SK VFO TEST) Retina. 2024 Dec 16. 回复：stana PE， Reinstein DZ， Valentin Bravo FJ等。治疗性屈光性玻璃体切除术（TRV）治疗玻璃体漂浮物和混浊（VFO），通过标准化和动态的玻璃体漂浮物和混浊的解剖和功能测试（SK VFO测试）视网膜评估。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-07 DOI: 10.1097/IAE.0000000000004591

Robert E Morris, Mathew R Sapp, Ferenc Kuhn

引用次数: 0

Real-World Efficacy of Intravitreal Methotrexate for Managing Proliferative Vitreoretinopathy in Recurrent Rhegmatogenous Retinal Detachment. 玻璃体内甲氨蝶呤治疗复发性孔源性视网膜脱离增生性玻璃体视网膜病变的实际疗效。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-03 DOI: 10.1097/IAE.0000000000004602

Justin S Yun, Blake H Fortes, Marcus H Yamamoto, Adrian C Au, Pradeep S Prasad, Colin A McCannel, Irena Tsui, Tara A McCannel, Hamid Hosseini, David Lozano Giral, Aya Barzelay-Wollman, Moritz S Pettenkofer, Kirk K Hou

{"title":"Real-World Efficacy of Intravitreal Methotrexate for Managing Proliferative Vitreoretinopathy in Recurrent Rhegmatogenous Retinal Detachment.","authors":"Justin S Yun, Blake H Fortes, Marcus H Yamamoto, Adrian C Au, Pradeep S Prasad, Colin A McCannel, Irena Tsui, Tara A McCannel, Hamid Hosseini, David Lozano Giral, Aya Barzelay-Wollman, Moritz S Pettenkofer, Kirk K Hou","doi":"10.1097/IAE.0000000000004602","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004602","url":null,"abstract":"Purpose: To evaluate the efficacy of serial intravitreal methotrexate (MTX) injections as an adjunct to surgical repair in the management of recurrent rhegmatogenous retinal detachment (rRRD) due to proliferative vitreoretinopathy (PVR).Methods: A retrospective cohort study was conducted involving 41 eyes with a history of failed RRD repair presenting with rRRD and grade C1 to D PVR, treated with pars plana vitrectomy (PPV) and serial MTX injections were included, separated into group 1 (with modified GUARD protocol, n=27) and group 2 (without modified GUARD protocol, n=14). The primary outcome was retinal reattachment rate, and secondary outcomes were changes in visual acuity and postoperative complications.Results: Retinal reattachment was achieved without additional surgery in 21 (77.8%) eyes in group 1 and 10 (71.4%) in group 2 at final follow-up, with no statistical significance. Improvement in logMAR was 0.50 in group 1 and 0.44 in group 2, with a median follow-up of 12.1 months from surgery and no differences in postoperative complications.Conclusion: There were no differences in retinal reattachment or visual acuity outcomes between both methotrexate regimens. The overall reattachment rate exceeded previously reported rates for rRRD with PVR. Further research is needed to optimize the injection protocol for better clinical outcomes.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0