Regional Variability in Choroidal Vascularity Index and Association with Intervortex Anastomoses in Polypoidal Choroidal Vasculopathy.

IF 2.1 2区医学 Q2 OPHTHALMOLOGY

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-07-07 DOI:10.1097/IAE.0000000000004590

Yu Jeat Chong, Kelvin Yi Chong Teo, Noa Gilead, Masahiro Akiba, Chui Ming Gemmy Cheung

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引用次数: 0

Abstract

Purpose: To evaluate the regional variation in choroidal vascularity index (CVI) in polypoidal choroidal vasculopathy (PCV) and association with intervortex anastomosis (IA).

Methods: Fifty-one eyes with PCV were included. Volumetric optical coherence tomography (OCT) scan was acquired on a 6 X 6mm2 macula area and divided into 36 individual squares. CVI was calculated using an automated algorithm. The different regions were: central, superior-temporal (ST), inferior-temporal (IT), superior-nasal (SN), inferior-nasal (IN). IA was detected using en-face OCT.

Results: The mean (SD) CVI of the whole macula was 61.01% (1.46), similar to all the other regions (pairwise comparison, all P >0.05). CVI range was 48.75%-69.48%. The mean (SD) coefficient of variation (CoV) was 1.9% (1.3).IA was present 64.7% of eyes. Eyes with IA had higher mean (SD) whole macula CVI (61.39% (1.43) versus 60.30% (1.26), P=0.01) and SFCT (265.8 µm (103.4) versus 190.1 µm (78.3), P =0.01) compared those without; and a lower mean (SD) CVI range (6.08% (2.38) versus 8.27% (4.13), P =0.04). Although the mean CVI CoV was lower in eyes with IA, 1.6% (0.8) versus 2.4% (1.8), this was not statistically significant, P=0.14.

Conclusion: Regional CVI variability may precede the formation of IA supporting the hypothesis that IA could be a compensatory mechanism for choroidal congestion.

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息肉样脉络膜血管病变脉络膜血管指数的区域变异及其与漩涡间吻合的关系。

目的：探讨息肉样脉络膜血管病变（polypoidal choroidal vascular pathy， PCV）脉络膜血管指数（CVI）的区域变化及其与漩涡吻合（intervortex吻合）的关系。方法：纳入51只PCV眼。在6 X 6mm2的黄斑区域进行体积光学相干断层扫描（OCT），并将其划分为36个单独的正方形。CVI采用自动算法计算。不同区域为：中央、颞上（ST）、颞下（IT）、上鼻（SN）、下鼻（IN）。结果：全黄斑的平均（SD） CVI为61.01%(1.46)，与其他区域相似（两两比较，P < 0.05）。CVI范围为48.75% ~ 69.48%。平均变异系数（CoV）为1.9%（1.3）。64.7%的眼睛存在IA。IA组的平均（SD）全黄斑CVI（61.39%（1.43）比60.30% (1.26)，P=0.01）和SFCT（265.8µm（103.4）比190.1µm (78.3)， P=0.01）高于无IA组；平均（SD） CVI范围较低（6.08%（2.38）对8.27% (4.13),P =0.04）。虽然IA眼的平均CVI CoV较低，分别为1.6%（0.8）和2.4%(1.8)，但差异无统计学意义，P=0.14。结论：区域CVI的变化可能先于IA的形成，支持IA可能是脉络膜充血的代偿机制的假设。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Retina-The Journal of Retinal and Vitreous Diseases 医学-眼科学

CiteScore

5.70

自引率

9.10%

发文量

554

审稿时长

3-6 weeks

期刊介绍： RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.