Retina-The Journal of Retinal and Vitreous Diseases最新文献_第9页

To the Editor-in-Chief: Reply to Grajewski and Kaymak regarding comments on Rodrigues and Falcão, "Bilateral multiple retinal serous detachments associated with FGFR inhibitor therapy". 致总编辑：回复Grajewski和Kaymak对Rodrigues和falc<e:1>的评论，“与FGFR抑制剂治疗相关的双侧多发性视网膜浆液性脱离”。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-10 DOI: 10.1097/IAE.0000000000004549

Inês Coelho-Costa, Rita Rodrigues, Manuel Falcão

引用次数: 0

Re: RETINA-224-1467. Response to Wang et al. regarding Gupta RR et al. Diagnostic and Therapeutic Challenges. Retina. 2024 Feb 1;44(2):364-368. 再保险:视网膜- 224 - 1467。对Wang等人关于Gupta RR等人的回应。诊断和治疗挑战。视网膜。2024年2月1日；44(2):364-368。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-10 DOI: 10.1097/IAE.0000000000004553

Rebekah H Gensure, Steven T Bailey

引用次数: 0

To the Editor-in-Chief. 给总编。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-10 DOI: 10.1097/IAE.0000000000004548

Rafael S Grajewski, Hakan Kaymak

引用次数: 0

Re: Gupta RR, et al. Diagnostic and Therapeutic Challenges. Retina. 2024 Feb 1;44(2):364-368. doi: 10.1097/IAE.0000000000003357. 回复：Gupta RR，等。诊断和治疗挑战。视网膜。2024年2月1日；44(2):364-368。doi: 10.1097 / IAE.0000000000003357。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-10 DOI: 10.1097/IAE.0000000000004552

Wenyu Wang, Changzheng Chen

引用次数: 0

Extensive Network of Outer Retinal Tubulations. 广泛的视网膜外小管网络。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-09 DOI: 10.1097/IAE.0000000000004546

Palak Patel, Bradley T Smith

引用次数: 0

ROLE OF AXIAL LENGTH ON POST-SURGICAL RETINAL DISPLACEMENT IN EYES TREATED FOR RHEGMATOGENOUS RETINAL DETACHMENT. 眼轴长度对孔源性视网膜脱离术后视网膜移位的影响。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-09 DOI: 10.1097/IAE.0000000000004544

Maura Mancini, Gregorio Lo Giudice, Claudio Brancato, Umberto Camellin, Alessandra Mancini, Alessandro Meduri, Pasquale Aragona, Antonino Pioppo

{"title":"ROLE OF AXIAL LENGTH ON POST-SURGICAL RETINAL DISPLACEMENT IN EYES TREATED FOR RHEGMATOGENOUS RETINAL DETACHMENT.","authors":"Maura Mancini, Gregorio Lo Giudice, Claudio Brancato, Umberto Camellin, Alessandra Mancini, Alessandro Meduri, Pasquale Aragona, Antonino Pioppo","doi":"10.1097/IAE.0000000000004544","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004544","url":null,"abstract":"Purpose: This study examines the role of axial length (AL) in the detection of retinal displacement in patients treated for rhegmatogenous retinal detachment (RRD) with pars plana vitrectomy (PPV).Methods: A total of 39 eyes from 39 patients undergoing PPV with tamponade using either 16% diluted hexafluoroethane gas (C2F6) or 1000-centistoke silicone oil were included. Retinal displacement and its direction were assessed via blue-fundus autofluorescence (B-FAF) imaging. The evaluated variables included AL, demographic data, white-to-white distance (WTW), trocar gauge ( 23 G vs 25 G ), type of retinopexy, intraoperative use of perfluorocarbon liquid (PFCL), number of detached quadrants, type of tamponade, postoperative metamorphopsia, and best-corrected visual acuity (BCVA).Results: Retinal displacement was detected in 28.2% of patients (11/39), with 90.9% (10 patients) having undergone gas tamponade (p = 0.004). AL was significantly associated with the detection of retinal displacement (p < 0.0001). Among the 21 patients who received gas tamponade, the incidence of displacement was 80% in those with AL > 26 mm compared to 18.2% in those with AL ≤ 26 mm (p = 0.018). The intraoperative use of PFCL also showed a positive correlation with retinal displacement (p = 0.002). Retinal displacement did not negatively impact BCVA but was significantly associated with postoperative metamorphopsia (p < 0.0001).Conclusions: Postoperative retinal displacement is significantly influenced by the type of tamponade, being more frequent with gas tamponade, and by the intraoperative use of PFCL. AL was associated with the detection of retinal displacement, although its causal role remains uncertain.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Prospective Observational Study of Intravitreal Aflibercept in Retinal Vein Occlusion with Initially Good Visual Acuity. 玻璃体内注射阿非利塞治疗初期视力良好的视网膜静脉阻塞的前瞻性观察研究。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-06 DOI: 10.1097/IAE.0000000000004543

Yusuke Koga, Yohei Otsuki, Kentaro Kojima, Natsuki Kusada, Kohsaku Numa, Hiroshi Tanaka, Chie Sotozono

{"title":"A Prospective Observational Study of Intravitreal Aflibercept in Retinal Vein Occlusion with Initially Good Visual Acuity.","authors":"Yusuke Koga, Yohei Otsuki, Kentaro Kojima, Natsuki Kusada, Kohsaku Numa, Hiroshi Tanaka, Chie Sotozono","doi":"10.1097/IAE.0000000000004543","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004543","url":null,"abstract":"Purpose: To clarify the effect of intravitreal aflibercept (IVA) injections in patients with branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO) presenting with best-corrected visual acuity (BCVA) better than 20/40.Methods: This prospective study included 61 eyes of 44 BRVO and 17 CRVO patients with untreated macular edema (ME). Patients whose ME improved within 3 months through the natural course were excluded. Patients administered IVA injections following treat-and-extend (TAE) regimen in which treatment intervals were adjusted every four weeks based on BCVA and central retinal thickness (CRT) stability. BCVA and CRT were measured before and up to 12 months. Retinal sensitivity (RS) measured by microperimetry (MP-1) and mean deviation (MD) values from the Humphrey 30-2 visual field analyzer (HFA) were evaluated at baseline, 6 and 12 months.Results: 35 BRVO and 14 CRVO patients completed the study. For BRVO patients, mean BCVA (logMAR) significantly improved from 0.19 ± 0.12 (Snellen equivalent, 20/31) to 0.06 ± 0.16 (20/23) at 12 months (p < 0.005), but not in CRVO patients (from 0.15 ± 0.13 [20/28] to 0.07 ± 0.16 [20/24]). Additionally, RS at 12 months improved significantly in both BRVO and CRVO (P < 0.001, P < 0.05, respectively). CRT showed a significant reduction in both groups (P < 0.001). There was no significant change in MD values in either group.Conclusions: IVA treatment using TAE regimen had a favorable visual prognosis for RVO-related ME with good initial BCVA, particularly in BRVO.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ring-Peeling: A Novel Fovea-sparing Internal Limiting Membrane Peeling Technique for Myopic Foveoschisis with Foveal Detachment. 环形剥离：一种新颖的保留中央凹内限制膜剥离技术治疗近视中央凹裂伴中央凹脱离。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-04 DOI: 10.1097/IAE.0000000000004527

Jiao Lyu, Dian Jiao, Peiquan Zhao

{"title":"Ring-Peeling: A Novel Fovea-sparing Internal Limiting Membrane Peeling Technique for Myopic Foveoschisis with Foveal Detachment.","authors":"Jiao Lyu, Dian Jiao, Peiquan Zhao","doi":"10.1097/IAE.0000000000004527","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004527","url":null,"abstract":"Purpose: To introduce a novel fovea-sparing internal limiting membrane (ILM) \"Ring-peeling\" technique and evaluate its effectiveness for treating myopic foveoschisis (MFS) with foveal detachment via pars plana vitrectomy (PPV).Methods: This technique was applied to 12 eyes (11 patients). During PPV, a 1-disc diameter (DD)-wide ILM flap was created, with its inner edge at least ¼ DD from the foveola. The flap was peeled tangentially toward the fovea and parallel to the inner retinal curvature. When the flap narrowed to half its original width, it was centrifugally extended. Intraoperative ILM peeling performance, postoperative anatomical and visual outcomes were measured.Results: During PPV, an ILM shield was preserved on the fovea in all eyes. In 10 eyes (83.3%), ILM peeling was continuous and based on a single ILM flap. After a follow-up of 20.2 ± 7.1 months, schisis cavities resolved and the fovea reattached in all eyes. The external limiting membrane was retrieved in 9 eyes (75%). BCVA improved in all eyes compared to preoperative levels, with 3 eyes achieving a BCVA above 20/50.Conclusion: This technique enhances the certainty of preserving an ILM shield on the fovea and achieves good postoperative visual and anatomical outcomes.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144267885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fluocinolone acetonide (FAc) implant in the treatment of retinal angiopathy macular edema in ATTR V30M patients. 氟西诺酮（FAc）植入治疗atr V30M患者视网膜血管性黄斑水肿。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-02 DOI: 10.1097/IAE.0000000000004542

Sofia Quintas Cales, Francisca Caiado Bragança, João Heitor Marques, João Magalhães Coelho, Maria João Menéres, João Melo Beirão

{"title":"Fluocinolone acetonide (FAc) implant in the treatment of retinal angiopathy macular edema in ATTR V30M patients.","authors":"Sofia Quintas Cales, Francisca Caiado Bragança, João Heitor Marques, João Magalhães Coelho, Maria João Menéres, João Melo Beirão","doi":"10.1097/IAE.0000000000004542","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004542","url":null,"abstract":"Purpose: to evaluate the effectiveness and safety of the fluocinolone acetonide implant (0.2 µg/day FAc, ILUVIEN®) in macular edema due to retinal amyloid angiopathy (RAA) in patients with hereditary transthyretin amyloidosis associated with the V30M mutation (ATTRV30M).Methods: retrospective observational case series of ATTRV30M patients' eyes treated with the implant for macular edema, from January 2010 to December 2019. Best corrected visual acuity (BCVA), central foveal thickness (CFT) and intraocular pressure (IOP) were measured at baseline, at 1 week, and at months 1, 3, 6, and 12.Results: fifteen eyes of 15 ATTRV30M patients with FAc implants were included. All patients had already received a liver transplant. All had already been submitted to cataract surgery, 87% had an Ahmed valve implant and 80% were vitrectomized due to vitreous amyloidosis. A statistically significant improvement in BCVA and in CFT at all time points was found compared to baseline. There was no statistically significant difference in IOP during the follow-up.Conclusions: patients with macular edema due to RAA treated with the FAc implant showed sustained increased functional results and anatomical improvement compared to baseline.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

QUANTITATIVE FLUORESCEIN ANGIOGRAPHY BIOMARKERS IN DIABETIC MACULAR EDEMA. 定量荧光素血管造影在糖尿病黄斑水肿中的生物标志物。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-06-01 DOI: 10.1097/IAE.0000000000004424

Ryan S Huang, Andrew Mihalache, Marko M Popovic, Colyn Munn, Isabela Martins Melo, Aurora Pecaku, Alon Friedman, Miguel Cruz Pimentel, Tina Tang, Peng Yan, David T Wong, Rajeev H Muni

{"title":"QUANTITATIVE FLUORESCEIN ANGIOGRAPHY BIOMARKERS IN DIABETIC MACULAR EDEMA.","authors":"Ryan S Huang, Andrew Mihalache, Marko M Popovic, Colyn Munn, Isabela Martins Melo, Aurora Pecaku, Alon Friedman, Miguel Cruz Pimentel, Tina Tang, Peng Yan, David T Wong, Rajeev H Muni","doi":"10.1097/IAE.0000000000004424","DOIUrl":"10.1097/IAE.0000000000004424","url":null,"abstract":"Purpose: To investigate the association between baseline clinical characteristics of patients with diabetic macular edema (DME) and quantitative intravenous fluorescein angiography (IVFA) parameters.Methods: Consecutive patients with DME presenting with a central macular thickness (CMT) ≥310 µ m were recruited from 2017 to 2023. Ultra-widefield IVFA images were analyzed with the RETICAD algorithm to extract quantitative measures of blood-retinal barrier (BRB) permeability, retinal perfusion, and blood flow. Univariable and multivariable regression models were used to investigate associations between IVFA parameters and baseline best-corrected visual acuity (BCVA), CMT, and macular volume.Results: The study population consisted of 56 eyes with DME, and seven eyes from healthy controls. In our multivariable analysis, BRB permeability measured in the central and peripheral retina was significantly associated with BCVA ( P = 0.003 and 0.002, respectively) and macular volume ( P = 0.025 and 0.045, respectively). Both central and peripheral BRB permeability were significantly higher in DME eyes relative to healthy controls ( P < 0.001).Conclusion: Increased BRB permeability measured on IVFA in DME eyes was associated with a greater baseline macular volume and worse BCVA, suggesting its potential in providing an objective assessment of disease severity. Future research should explore the clinical utility of quantitative IVFA measurements in diverse patient populations.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"1125-1133"},"PeriodicalIF":2.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0