Retina-The Journal of Retinal and Vitreous Diseases最新文献

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Letter to the Editor concerning the manuscript entitled "PRETREATED LYOPHILIZED HUMAN AMNIOTIC MEMBRANE GRAFT COVERING FOR RETINAL DETACHMENT WITH POSTERIOR RETINAL BREAKS ABOVE CHORIORETINAL ATROPHY IN PATHOLOGIC MYOPIA". 致编辑的信,关于题为“病理性近视后视网膜破裂后绒毛膜视网膜萎缩的经预处理的冻干人羊膜移植覆盖视网膜脱离”的稿件。
IF 2.3 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-12 DOI: 10.1097/IAE.0000000000004302
Thibaud Garcin
{"title":"Letter to the Editor concerning the manuscript entitled \"PRETREATED LYOPHILIZED HUMAN AMNIOTIC MEMBRANE GRAFT COVERING FOR RETINAL DETACHMENT WITH POSTERIOR RETINAL BREAKS ABOVE CHORIORETINAL ATROPHY IN PATHOLOGIC MYOPIA\".","authors":"Thibaud Garcin","doi":"10.1097/IAE.0000000000004302","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004302","url":null,"abstract":"","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-World Long-Term Outcomes of Intravitreal Faricimab in Previously Treated Chronic Neovascular Age-Related Macular Degeneration. 曾接受过治疗的慢性新生血管性年龄相关性黄斑变性的玻璃体内法利西单抗的真实世界长期疗效。
IF 2.3 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-11 DOI: 10.1097/IAE.0000000000004322
Naveen R Ambati, Adam Leone, Daniel Brill, Robert A Sisk
{"title":"Real-World Long-Term Outcomes of Intravitreal Faricimab in Previously Treated Chronic Neovascular Age-Related Macular Degeneration.","authors":"Naveen R Ambati, Adam Leone, Daniel Brill, Robert A Sisk","doi":"10.1097/IAE.0000000000004322","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004322","url":null,"abstract":"<p><strong>Purpose: </strong>To study the real-world outcomes of intravitreal faricimab (IVF) in longstanding neovascular age-related macular degeneration (nAMD) over a one-year study period.</p><p><strong>Methods: </strong>Retrospective single-center cohort study of patients with previously treated nAMD receiving IVF with at least 12 months of follow up. Main outcome measures include injection intervals, visual acuity (VA), and optical coherence tomography features.</p><p><strong>Results: </strong>263 eyes from 217 patients received 6.4±2.3 IVF injections over one year. Injection interval increased after switching to IVF (5.9±1.8 vs 7.6±2.4 weeks) (p<0.01). There was no improvement in VA after switching to IVF at any time period (p>0.15). Average CST decreased after the first IVF injection and was sustained for one year (313.7±96.0 vs. 288.2±80.6 μm) (p<0.01). There was a statistically significant resolution of subretinal fluid but not IRF at all time points (40.8-50.4%) (p<0.01). Persistent fluid after the first IVF injection was resolved in 34.4% (n=45) by one year. IVF was discontinued in 31 eyes (11.8%), four (1.6%) that experienced intraocular inflammation.</p><p><strong>Conclusions: </strong>Longstanding nAMD eyes switched to IVF experienced a significant extension in injection interval, stable visual acuity, improvement in CST, and resolution of fluid on OCT in many patients over one year.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adaptive Optics Ophthalmoscopy Reveals Subclinical Arteritis and Periphlebitis after Intravitreal Brolucizumab Injection.
IF 2.3 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-07 DOI: 10.1097/IAE.0000000000004328
Yoo-Ri Chung, Nathalie Massamba, Adélaïde Toutée, Michel Paques, Sara Touhami, Bahram Bodaghi
{"title":"Adaptive Optics Ophthalmoscopy Reveals Subclinical Arteritis and Periphlebitis after Intravitreal Brolucizumab Injection.","authors":"Yoo-Ri Chung, Nathalie Massamba, Adélaïde Toutée, Michel Paques, Sara Touhami, Bahram Bodaghi","doi":"10.1097/IAE.0000000000004328","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004328","url":null,"abstract":"","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
" LIGHTSITE III: 13-Month Efficacy and Safety Evaluation of Multiwavelength Photobiomodulation in Nonexudative (Dry) Age-Related Macular Degeneration Using the LumiThera Valeda Light Delivery System ". "LIGHTSITE III:使用 LumiThera Valeda 光传输系统对非渗出性(干性)年龄相关性黄斑变性进行为期 13 个月的多波长光生物调节的疗效和安全性评估"。
IF 4.6 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-01 DOI: 10.1097/IAE.0000000000004266
David Boyer, Marion R Munk, Stephanie E Tedford, Cindy L Croissant, Rene Rückert, Clark E Tedford
{"title":"\" LIGHTSITE III: 13-Month Efficacy and Safety Evaluation of Multiwavelength Photobiomodulation in Nonexudative (Dry) Age-Related Macular Degeneration Using the LumiThera Valeda Light Delivery System \".","authors":"David Boyer, Marion R Munk, Stephanie E Tedford, Cindy L Croissant, Rene Rückert, Clark E Tedford","doi":"10.1097/IAE.0000000000004266","DOIUrl":"10.1097/IAE.0000000000004266","url":null,"abstract":"","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":4.6,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11559959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MACULAR THICKNESS FLUCTUATIONS AND VISUAL ACUITY OUTCOMES AFTER INTRAVITREAL DEXAMETHASONE IMPLANT FOR DIABETIC MACULAR EDEMA. 玻璃体内地塞米松植入治疗糖尿病性黄斑水肿后的黄斑厚度波动和视力效果。
IF 2.3 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-01 DOI: 10.1097/IAE.0000000000004213
Héloïse Torres-Villaros, Rhyme Timoumi, Franck Fajnkuchen, Arnaud Klokner, Audrey Giocanti-Aurégan
{"title":"MACULAR THICKNESS FLUCTUATIONS AND VISUAL ACUITY OUTCOMES AFTER INTRAVITREAL DEXAMETHASONE IMPLANT FOR DIABETIC MACULAR EDEMA.","authors":"Héloïse Torres-Villaros, Rhyme Timoumi, Franck Fajnkuchen, Arnaud Klokner, Audrey Giocanti-Aurégan","doi":"10.1097/IAE.0000000000004213","DOIUrl":"10.1097/IAE.0000000000004213","url":null,"abstract":"<p><strong>Purpose: </strong>To assess macular thickness fluctuations and their association with visual acuity outcomes in eyes with diabetic macular edema treated with an intravitreal dexamethasone (DEX) implant.</p><p><strong>Methods: </strong>The SD of all postbaseline central subfield thicknesses (CST) recorded over a 12-month period after the first injection of the DEX implant was used to quantify CST fluctuations. Linear regression models were used to identify factors associated with the visual acuity at 12 months (measured with the Early Treatment of Diabetic Retinopathy Study score) and predictors of CST SD.</p><p><strong>Results: </strong>A retrospective review of 80 eyes of 80 patients treated with the DEX implant for diabetic macular edema revealed a CST SD of 75.3 ± 50.3 µ m. The CST SD was negatively associated with the visual acuity at 12 months (-7.7 Early Treatment of Diabetic Retinopathy Study letters for each 100- µ m increase in CST SD, P = 0.01), while changes in CST from baseline did not show any significant association. Eyes were stratified into quartiles based on the CST SD, and a difference by -14.2 letters in visual acuity at 12 months was observed between the first and fourth quartiles ( P <0.001). Significant predictors of CST SD included the baseline visual acuity (-12.0 µ m for each 10-letter increase, P = 0.02) and the number of DEX injections received (n = 17.1, P = 0.03).</p><p><strong>Conclusion: </strong>Greater fluctuations in retinal thickness were found to be associated with poorer visual outcomes in eyes with diabetic macular edema treated with the DEX implant. Analyzing the CST SD could be a more predictive indicator of visual prognosis than individual measurements of the CST.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"1937-1944"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142114738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COMPARISON OF CHOROIDAL VASCULATURE BETWEEN CENTRAL SEROUS CHORIORETINOPATHY WITH AND WITHOUT THICK CHOROID USING SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY. 使用扫源光学相干断层血管成像技术比较有和没有厚脉络膜的中央浆液性脉络膜视网膜病变的脉络膜血管。
IF 2.3 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-01 DOI: 10.1097/IAE.0000000000004190
Qiaozhu Zeng, Yuou Yao, Shu Tu, Mingwei Zhao
{"title":"COMPARISON OF CHOROIDAL VASCULATURE BETWEEN CENTRAL SEROUS CHORIORETINOPATHY WITH AND WITHOUT THICK CHOROID USING SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.","authors":"Qiaozhu Zeng, Yuou Yao, Shu Tu, Mingwei Zhao","doi":"10.1097/IAE.0000000000004190","DOIUrl":"10.1097/IAE.0000000000004190","url":null,"abstract":"<p><strong>Purpose: </strong>To distinguish between central serous chorioretinopathy (CSC) with and without thick choroid and to elucidate their characteristics of choroidal vasculature.</p><p><strong>Methods: </strong>This prospective observational study enrolled 76 eyes with treatment-naive CSC and 76 normal eyes. Mean + 2 times SD of subfoveal choroidal thickness of healthy individuals was set as the upper limit of normal choroidal thickness to divide patients with CSC into two groups: the thick-choroid and non-thick-choroid groups. Their choroid blood flow was compared using widefield swept-source optical coherence tomography angiography.</p><p><strong>Results: </strong>According to the discrimination value of subfoveal choroidal thickness as 326.8 µm, 76 eyes with CSC were divided into the thick-choroid (55, 72.4%) and non-thick-choroid (21, 27.6%) groups. Higher proportions of vortex vein anastomosis were found in the thick-choroid group (81.8% vs. 33.3%, P < 0.001). Choroid thickness, three-dimensional choroidal vascularity index, and mean choroidal stroma volume per 1 mm2 were higher in the thick-choroid group. In multivariate analysis, younger age, higher percentages of vortex vein anastomosis, and double layer sign were the independent predictors of choroid thickening in CSC.</p><p><strong>Conclusion: </strong>There are discrepancies in the degree of choroidal congestion and distribution of vortex veins in the CSC with different choroidal thicknesses.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":"44 11","pages":"1983-1991"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GUNN DOTS IN CHILDREN AGED 11-12 YEARS FROM THE GENERAL COMMUNITY SAMPLE COPENHAGEN CHILD COHORT 2000 STUDY. 哥本哈根儿童队列 2000 研究一般社区样本中 11-12 岁儿童的 gunn 点。
IF 2.3 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-01 DOI: 10.1097/IAE.0000000000004187
Lars Christian Boberg-Ans, Inger Christine Munch, Else Marie Olsen, Anne Mette Skovgaard, Michael Larsen
{"title":"GUNN DOTS IN CHILDREN AGED 11-12 YEARS FROM THE GENERAL COMMUNITY SAMPLE COPENHAGEN CHILD COHORT 2000 STUDY.","authors":"Lars Christian Boberg-Ans, Inger Christine Munch, Else Marie Olsen, Anne Mette Skovgaard, Michael Larsen","doi":"10.1097/IAE.0000000000004187","DOIUrl":"10.1097/IAE.0000000000004187","url":null,"abstract":"<p><strong>Purpose: </strong>To study characteristics and associations of Gunn dots in a cohort of healthy children aged 11 to 12 years.</p><p><strong>Methods: </strong>As part of the Copenhagen Child Cohort 2000 Study, red-free fundus photographs were taken on 761 healthy children aged 11 to 12 years. The photographs were centered on the optic disk. Gunn dots were annotated and counted within a disk-centered circular grid of 6 mm diameter. Data were analyzed in relation to age, sex, axial length, and retinal nerve fiber layer thickness.</p><p><strong>Results: </strong>Gunn dots were found in 716 of the 761 participants (94%). The majority of dots were located both inferior and superior to the optic disk, situated within a distance of 3 mm from its center. The median number of Gunn dots was 64 (range 0-574) in right eyes and 68 (range 0-532) in left eyes. Having more than the median number of Gunn dots in the right eye was associated with older age (odds ratio 2.12, 95% CI 1.56 to 2.89, P < 0.0001, adjusted for sex, axial length, and retinal nerve fiber layer thickness) and was less common among the children with a thinner retinal nerve fiber layer (odds ratio 0.40, 95% CI 0.26-0.60, P < 0.0001 comparing bottom and top quartiles).</p><p><strong>Conclusion: </strong>Gunn dots were visible in the majority of healthy children aged 11 to 12 years, and large numbers of dots were associated with a thicker nerve fiber layer and with older age, within the limited age range of 1 year. The clinical significance of Gunn dots is unknown. Their location at the vitreoretinal interface makes them a parameter of interest in the study of aging, epiretinal fibrosis, macular pucker and retinal detachment.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":"44 11","pages":"1961-1965"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142481039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EXPLORING THE CHALLENGES OF DISTINGUISHING PUNCTATE INNER CHOROIDOPATHY FROM MULTIFOCAL CHOROIDITIS AND PANUVEITIS. 探索将点状内脉络膜病变与多灶性脉络膜炎和泛脉络膜炎区分开来的难题。
IF 2.3 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-01 DOI: 10.1097/IAE.0000000000004211
Hyo Song Park, Hyun Goo Kang, Yong Joon Kim, Eun Young Choi, Junwon Lee, Suk Ho Byeon, Sung Soo Kim, Christopher Seungkyu Lee
{"title":"EXPLORING THE CHALLENGES OF DISTINGUISHING PUNCTATE INNER CHOROIDOPATHY FROM MULTIFOCAL CHOROIDITIS AND PANUVEITIS.","authors":"Hyo Song Park, Hyun Goo Kang, Yong Joon Kim, Eun Young Choi, Junwon Lee, Suk Ho Byeon, Sung Soo Kim, Christopher Seungkyu Lee","doi":"10.1097/IAE.0000000000004211","DOIUrl":"10.1097/IAE.0000000000004211","url":null,"abstract":"<p><strong>Purpose: </strong>This retrospective case series aimed to assess the concordance between clinical diagnoses of punctate inner choroidopathy and multifocal choroiditis and panuveitis (MCP) using the 2021 Standardization of Uveitis Nomenclature Working Group criteria.</p><p><strong>Methods: </strong>Using the medical records of the patients, the authors reevaluated 100 eyes of 75 patients with idiopathic multifocal chorioretinal inflammatory lesions based on Standardization of Uveitis Nomenclature criteria and compared the result with the clinical diagnosis.</p><p><strong>Results: </strong>Of 100 eyes, 29 eyes (29%) were diagnosed as punctate inner choroidopathy and 15 eyes (15%) were diagnosed as MCP using Standardization of Uveitis Nomenclature criteria, and 56 (56%) eyes could not be diagnosed as either. Clinically diagnosed punctate inner choroidopathy eyes were significantly more myopic than the clinically diagnosed MCP eyes (mean spherical equivalent -6.65 ± 4.63 vs. -3.85 ± 2.31, P = 0.01). Sixteen eyes with vitreous inflammation were all clinically diagnosed as MCP, but four (25%) could not be diagnosed as MCP using Standardization of Uveitis Nomenclature criteria.</p><p><strong>Conclusion: </strong>The existing diagnostic criteria showed limitations in capturing all clinical cases of punctate inner choroidopathy or MCP, and adding or revising criteria on features such as vitreous inflammation or myopia could be considered to enhance diagnostic accuracy.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"1869-1875"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PROGRESSION OF PERIPAPILLARY AND MACULAR CHORIORETINAL ATROPHY IN MULTIFOCAL CHOROIDITIS IS ASSOCIATED WITH PERIATROPHIC INFLAMMATORY PLUMES. 多灶性脉络膜炎的毛细血管周围和黄斑脉络膜视网膜萎缩的进展与周围炎性羽状细胞有关。
IF 2.3 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-01 DOI: 10.1097/IAE.0000000000004227
Jeannette Ossewaarde-van Norel, Richard F Spaide
{"title":"PROGRESSION OF PERIPAPILLARY AND MACULAR CHORIORETINAL ATROPHY IN MULTIFOCAL CHOROIDITIS IS ASSOCIATED WITH PERIATROPHIC INFLAMMATORY PLUMES.","authors":"Jeannette Ossewaarde-van Norel, Richard F Spaide","doi":"10.1097/IAE.0000000000004227","DOIUrl":"10.1097/IAE.0000000000004227","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate peripapillary atrophy and macular chorioretinal scars in eyes affected by multifocal choroiditis and panuveitis.</p><p><strong>Methods: </strong>This retrospective cohort study reviewed the medical records, fundus photographs, and spectral-domain optical coherence tomographic scans of 31 eyes from 19 patients.</p><p><strong>Results: </strong>Patients had a mean age of 45 years (range 24-69 years). The average follow-up duration was 7 years (range, 2.5-14.5 years), with 14 patients undergoing immunosuppressive treatment. In the group of 31 eyes, 20 showed peripapillary plumes of ill-defined hyperreflectivity at the termination border of the retinal pigment epithelium. These plumes, extending from bare Bruch membrane to the outer nuclear layer, sometimes undermined the adjacent retinal pigment epithelium. They responded to corticosteroid treatment and resembled the material under the retinal pigment epithelium in acute lesions. Among 20 eyes with these peripapillary inflammatory lesions, 16 (80%) experienced increased atrophy, in contrast to none in the eyes without these lesions ( P < 0.001). Similar patterns were observed at the edges of macular chorioretinal atrophy. This observation occurred in patients using immunosuppressive medication who were otherwise thought to be under adequate control.</p><p><strong>Conclusion: </strong>In patients with multifocal choroiditis and panuveitis, previously unrecognized plumes of smoldering inflammatory activity at the borders of chorioretinal atrophy appears to be linked to atrophy expansion. The recognition of this phenomenon may require a reappraisal of treatment of multifocal choroidopathies to help mitigate the expansion of atrophy in these eyes.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"1860-1868"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
PERFLUOROCARBON LIQUID USE DURING VITRECTOMY FOR MACULA-OFF RETINAL DETACHMENT HAS NO IMPACT ON MACULAR FOLDS AND METAMORPHOPSIA. 在玻璃体切除术中使用全氟碳化物液治疗黄斑-视网膜脱离对黄斑皱褶和变形视力没有影响。
IF 2.3 2区 医学
Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-11-01 DOI: 10.1097/IAE.0000000000004220
Mathieu Wurtz, Lea Dormegny, Candice Muller, Tristan Bourcier, Laurent Ballonzoli, David Gaucher, Maher Saleh
{"title":"PERFLUOROCARBON LIQUID USE DURING VITRECTOMY FOR MACULA-OFF RETINAL DETACHMENT HAS NO IMPACT ON MACULAR FOLDS AND METAMORPHOPSIA.","authors":"Mathieu Wurtz, Lea Dormegny, Candice Muller, Tristan Bourcier, Laurent Ballonzoli, David Gaucher, Maher Saleh","doi":"10.1097/IAE.0000000000004220","DOIUrl":"10.1097/IAE.0000000000004220","url":null,"abstract":"<p><strong>Purpose: </strong>To compare two drainage techniques in macula-off retinal detachment surgery: perfluorocarbon liquid (PFCL)-assisted drainage and partial subretinal fluid drainage without PFCL. This study investigated morphological and functional outcomes, focusing on metamorphopsia quantification.</p><p><strong>Methods: </strong>Eighty eyes with macula-off retinal detachment were retrospectively included. All underwent a 25-gauge pars plana vitrectomy. In the PFCL group, subretinal fluid drainage was performed using PFCL. In the partial subretinal fluid drainage (SRFD) group, subretinal fluid was partially drained through a preexisting retinal break without PFCL. A follow-up at 3 months and 6 months evaluated anatomical outcomes using optical coherence tomography, best-corrected visual acuity, and metamorphopsia quantified with M-charts.</p><p><strong>Results: </strong>Reattachment rates were comparable in the PFCL group (97.5%) and the SRFD group (95%) ( P > 0.05). Mean best-corrected visual acuity (logMAR) was 0.23 ± 0.32 (PFCL group) and 0.15 ± 0.13 (SRFD group) ( P = 0.206). Metamorphopsia was reported by 19 patients (47.5%) in the PFCL group and by 12 patients (30%) in the SRFD group ( P = 0.332). The mean metamorphopsia score was similar in both groups (0.27 ± 0.12 in the PFCL group and 0.28 ± 0.11 in the SRFD group, P = 0.866). Morphological optical coherence tomography findings were comparable in both groups.</p><p><strong>Conclusion: </strong>Morphological and functional outcomes were similar in PFCL and SRFD groups. Metamorphopsia quantification scores did not improve with PFCL. While both of these techniques might be effective and could be recommended for primary macula-off retinal detachment management, potential PFCL toxicity should be kept in mind and its use dedicated to selected cases.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":"1891-1898"},"PeriodicalIF":2.3,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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