Journal of the Pakistan Medical Association最新文献_第5页

Awareness of free access to radiotherapy: cyberknife stereotactic radiosurgery, in Pakistan. 认识到免费获得放射治疗：射波刀立体定向放射外科手术，在巴基斯坦。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-04-01 DOI: 10.47391/JPMA.21973

Ali Nasir, Misbah Kaleem

引用次数: 0

Neonatal tetanus with intestinal atresia, the importance of multidisciplinary management: a case report. 新生儿破伤风合并肠闭锁，多学科管理的重要性：1例报告。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-04-01 DOI: 10.47391/JPMA.20733

GhTaimur Iftikhar Qureshi, Muhammad Arshad

引用次数: 0

Leveraging GIS for Empowering Health Research in Pakistan: A Path to Smarter Public Health Solutions. 利用地理信息系统增强巴基斯坦卫生研究能力：通往更智能的公共卫生解决方案之路。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-04-01 DOI: 10.47391/JPMA.25-26

Masood Ali Shaikh, Syed Muhammad Mubeen

引用次数: 0

Investigating fibrinogen levels as a biomarker for immune inflammation severity in COPD patients across GOLD stages. 研究纤维蛋白原水平作为COPD患者GOLD分期免疫炎症严重程度的生物标志物。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-04-01 DOI: 10.47391/JPMA.11531

Sajjad Ali, Ishtiaq Ahmad

{"title":"Investigating fibrinogen levels as a biomarker for immune inflammation severity in COPD patients across GOLD stages.","authors":"Sajjad Ali, Ishtiaq Ahmad","doi":"10.47391/JPMA.11531","DOIUrl":"https://doi.org/10.47391/JPMA.11531","url":null,"abstract":"Objectives: To assess the association between fibrinogen levels and immune inflammation severity in patients with chronic obstructive pulmonary disease at different stages of the Global Initiative for Chronic Obstructive Lung Disease classification.Methods: The descriptive, prospective, cross-sectional study was conducted from January 2022 to November 2023 at the Pulmonology Department, Mardan Medical Complex, Khyber Pakhtunkhwa, Pakistan, and comprised chronic obstructive pulmonary disease patients of either gender aged 40-85 years. Fibrinogen levels and systemic immuneinflammatory markers were measured, and disease severity was classified based on the Global Initiative for Chronic Obstructive Lung Disease classification. Independent predictors of fibrinogen levels as well as the diagnostic accuracy of biomarkers for predicting advanced chronic obstructive pulmonary disease were identified. Data was analysed using SPSS 26.Results: Of the 253 patients, 147(58.10%) were males and 106(41.89%) were females. Most of the patients were aged 40-50 years 72(28.45%), followed by 50-60 years 57(22.52%). A strong positive correlation was observed between fibrinogen levels and chronic obstructive pulmonary disease severity (r=0.815, p<0.001). The diagnostic accuracy of fibrinogen for predicting advanced disease stages was reliable, having an area under the curve of 0.910.Conclusions: Fibrinogen levels could be used as a marker for immune inflammation severity in chronic obstructive pulmonary disease patients.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 4","pages":"556-563"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Over the counter naloxone nasal spray: A new hope for opioid crisis management in Pakistan. 非处方纳洛酮鼻喷雾剂：巴基斯坦阿片类药物危机管理的新希望。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-03-01 DOI: 10.47391/JPMA.21348

Zmarak Ahmed Khan, Zainab Anfaal, Muhammad Shaheer

引用次数: 0

Digital dilemma: Navigating the nexus of nomophobia, phantom vibration syndrome and psychological disorders. 数字困境：在无手机恐惧症、幽灵振动综合症和心理障碍之间的联系中导航。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-03-01 DOI: 10.47391/JPMA.21182

Safia Kundi, Parah Gul

引用次数: 0

Management of pemphigus during COVID-19 pandemic era: An experience of single centre. COVID-19大流行时期天疱疮的管理：单一中心的经验。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-03-01 DOI: 10.47391/JPMA.10935

Sahibzada Mahmood Noor, Farah Sagheer, Adan Sardar

引用次数: 0

A case of Kasabach-Merritt Syndrome in a nine-month-old: A rare complication of haemangioma in the young. 9个月大的卡萨巴赫-梅里特综合征1例：血管瘤罕见的并发症。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-03-01 DOI: 10.47391/JPMA.11607

Hafiz Khalid Pervaiz, Usman Jamil Mughal, Izza Ali Rai, Mumtaz Touseef, Aliezeh Fatima Rai

引用次数: 0

Visual impairment and blindness in Alkharj, Saudi Arabia. 沙特阿拉伯阿尔哈尔吉的视力障碍和失明。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-03-01 DOI: 10.47391/JPMA.20043

Nasraddin Othman Bahakim, Ayman Ibrahim Geddawy, Abdulrahman Ibrahim Aldarrab, Mansour Mohammad Alajmi, Mohammed Saoud Alsaidan, Maher Faleh Aljuhani, Abdulqayyum Hussain, Abdulhakim Saeed Alqahtani, Abdulmajeed Mohammed Alshaikhi, Sameer Hamed Al-Ghamdi

{"title":"Visual impairment and blindness in Alkharj, Saudi Arabia.","authors":"Nasraddin Othman Bahakim, Ayman Ibrahim Geddawy, Abdulrahman Ibrahim Aldarrab, Mansour Mohammad Alajmi, Mohammed Saoud Alsaidan, Maher Faleh Aljuhani, Abdulqayyum Hussain, Abdulhakim Saeed Alqahtani, Abdulmajeed Mohammed Alshaikhi, Sameer Hamed Al-Ghamdi","doi":"10.47391/JPMA.20043","DOIUrl":"10.47391/JPMA.20043","url":null,"abstract":"Objective: To determine the incidence and causes of visual impairment and blindness among patients attending eye clinics in a tertiary care setting.Methods: The retrospective study was conducted in Alkharj city, Saudi Arabia, from May to November 2022, and comprised records of patients who visited eye clinics of two main hospitals in the city with complaints of low vision or blindness between January 2021 and December 2021. Medical history, family history and ophthalmological examination results of each patient were reviewed, and the causes and frequency of occurrence of visual impairment and blindness were determined. Data was analysed using SPSS 21.Results: Of the 433 patients, 269(62.1%) were female and 164(37.9%) were male. The overall mean age was 38.52±21.90 years (range; 5-90 years) with a median age of 37 years (IQR: 19-58). Refractive error 271(62.6%), cataract 69(15.9%) and diabetic retinopathy 37(8.5%) were the major causes of visual impairment, followed by amblyopia 15(3.5), corneal opacity 12(2.8), and glaucoma 8(1.8). Refractive errors, amblyopia, and corneal opacity were more common among those aged 5-20 years, while visual impairment caused by cataract, diabetic retinopathy and glaucoma was more common in older age groups.Conclusions: Refractive error was found to be the major cause among the participants with mild to severe visual impairment.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"418-423"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term antibody response after COVID-19 vaccination in health care workers: A single centre study from Pakistan. 卫生保健工作者在COVID-19疫苗接种后的长期抗体反应：来自巴基斯坦的单中心研究

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2025-03-01 DOI: 10.47391/JPMA.20351

Fatima Kanani, Javeria Ejaz, Sabiha Anis, Mamoona Mushtaq

{"title":"Long-term antibody response after COVID-19 vaccination in health care workers: A single centre study from Pakistan.","authors":"Fatima Kanani, Javeria Ejaz, Sabiha Anis, Mamoona Mushtaq","doi":"10.47391/JPMA.20351","DOIUrl":"10.47391/JPMA.20351","url":null,"abstract":"The retrospective cohort study was planned to determine long-term anti-spike immunoglobulin G levels after receiving coronavirus disease-2019 vaccination by healthcare workers. The study took place between June and July 2022 at the Indus hospital in Karachi. Healthcare workers who had previously screened negative to prevaccination Severe Acute Respiratory Syndrome Coronavirus 2 nucleocapsid antibodies were tested for post-vaccination Severe Acute Respiratory Syndrome Coronavirus 2 anti-spike immunoglobulin G levels using a quantitative assay. The test was also performed on the stored pre-vaccination samples of the subjects collected up to 18 months previously. Antibody levels in subjects without infection, with infection and with booster administration were compared. The median postvaccination anti-spike immunoglobulin G in infected only, infected with routine vaccination and infected with booster values were 1,725.6 IU/mL (interquartile range: 684.80- 4,708.9 IU/mL), 2,067.15 IU/mL (interquartile range: 705.33-4,670.4 IU/mL) and 6,139.15 IU/mL (interquartile range: 2,426.05-10,623.40 IU/mL). There was a doubling of antibody titers, from 1,744 IU/mL to 3,829 IU/mL, in those who received a booster versus routine vaccination (p>0.05). The antibodies remained positive more than a year following vaccination.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"472-475"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0