{"title":"Use of metformin in treatment of dengue fever.","authors":"Zainab Irfan, Hasan Zia Yaqub","doi":"10.47391/JPMA.20931","DOIUrl":"https://doi.org/10.47391/JPMA.20931","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 2","pages":"365"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Student-run free clinics (SRFCs) can solve three problems for Pakistan.","authors":"Bashir Ahmad, Rabia Wazir","doi":"10.47391/JPMA.21126","DOIUrl":"https://doi.org/10.47391/JPMA.21126","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 2","pages":"368"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Umar Rafique, Ayeeza Asghar, Abdullah Ahmad
{"title":"Optimizing iron absorption: Superiority of alternate day dosing.","authors":"Muhammad Umar Rafique, Ayeeza Asghar, Abdullah Ahmad","doi":"10.47391/JPMA.21109","DOIUrl":"https://doi.org/10.47391/JPMA.21109","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 2","pages":"367"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aamna Khatoon, Fatima Kaleem Ahmed, Amna Kaleem Ahmed
{"title":"Trailblazer Tepezza for thyroid.","authors":"Aamna Khatoon, Fatima Kaleem Ahmed, Amna Kaleem Ahmed","doi":"10.47391/JPMA.20296","DOIUrl":"https://doi.org/10.47391/JPMA.20296","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 2","pages":"354"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"More than just a broken limb: Unmasking CRPS in Pakistan.","authors":"Zahra Aamir Khan","doi":"10.47391/JPMA.21043","DOIUrl":"https://doi.org/10.47391/JPMA.21043","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 2","pages":"366"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Capvaxive (V116): A new frontier in the prevention of pneumococcal pneumonia and invasive disease.","authors":"Syed Ali Wijdan, Muhammad Mustafa","doi":"10.47391/JPMA.21318","DOIUrl":"https://doi.org/10.47391/JPMA.21318","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 2","pages":"370-371"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The synergy of linagliptin and empagliflozin in catering to diabetes mellitus in Pakistan.","authors":"Ainan Arshad, Kashif Khan, Muhammad Shoaib","doi":"10.47391/JPMA.11145","DOIUrl":"https://doi.org/10.47391/JPMA.11145","url":null,"abstract":"<p><p>Diabetes is rapidly increasing globally, especially in lowand middle-income countries, with Pakistan ranking third in prevalence, having 33 million people. The lack of adherence to the first-line treatment, metformin, mainly due to gastrointestinal side effects, is a significant concern. A novel approach for managing type 2 diabetes in Pakistan is to combine linagliptin and empagliflozin. Linagliptin is well-tolerated and suitable for those who cannot tolerate metformin, while empagliflozin reduces cardiovascular risks and nephropathy, showing promising results in controlling diabetes with minimal side effects. The synergy between linagliptin and empagliflozin could greatly improve diabetes management and patient wellbeing. It is recommended that healthcare providers in Pakistan use social media and seminars to educate the public on this new treatment option to tackle the diabetes crisis effectively.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 2","pages":"290-292"},"PeriodicalIF":0.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143416239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Administration of aspirin and risk of pancreatic ductal adenocarcinoma.","authors":"Arooba Affan Abbasi, Fatimah Bismah Athar, Arooba Lakho","doi":"10.47391/JPMA.20483","DOIUrl":"https://doi.org/10.47391/JPMA.20483","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 1","pages":"172-173"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saqib Habib, Shahrukh Ali Khan, Aqeel Ahmed, Farhan Raza Khan
{"title":"Biobanking of human teeth for stem cell storage: Preserving stem cells for future needs.","authors":"Saqib Habib, Shahrukh Ali Khan, Aqeel Ahmed, Farhan Raza Khan","doi":"10.47391/JPMA.20013","DOIUrl":"https://doi.org/10.47391/JPMA.20013","url":null,"abstract":"<p><p>Human teeth serves as a potential reservoir for postembryonic mesenchymal dental stem cells. Researchers have identified and isolated seven types of dental stem cells from pulp and periodontal ligament tissues. These cells have a wide range of clinical applications across the fields of medicine and dentistry due to their increased proliferative nature. Biobanking is a concept for storing human biological tissues to preserve and isolate stem cells. Until now, haematopoietic tissues have been the area of focus for biobanking facilities. Extracted human teeth may serve as a valuable resource for the isolation and preservation of dental stem cells for future therapeutic benefits. The current narrative review was planned to focus on the workflow of the teeth biobanking process, its isolation, cryopreservation, and potential therapeutic uses in medical and dental specialtiesxx.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 1","pages":"91-95"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadeem Bin Nusrat, Kilian Walsh, Frank Darcy, Garrett Durkan, Asadullah Aslam, Saira Imtiaz
{"title":"Evaluation of surgical outcomes of nephron-sparing surgery in a leading hospital of an advanced nation.","authors":"Nadeem Bin Nusrat, Kilian Walsh, Frank Darcy, Garrett Durkan, Asadullah Aslam, Saira Imtiaz","doi":"10.47391/JPMA.11367","DOIUrl":"https://doi.org/10.47391/JPMA.11367","url":null,"abstract":"<p><strong>Objective: </strong>To assess the efficacy of renal score grading in guiding therapy decisions, predicting perioperative outcomes, and characterising tumours following partial nephrectomy.</p><p><strong>Methods: </strong>The retrospective, single-centre study was conducted at the University College Hospital Galway, Ireland, and comprised data from January 11, 2012, to June 17, 2016, of all patients aged >18 years who underwent partial nephrectomy as part of treatment for kidney cancer. Data was analysed using SPSS 20.</p><p><strong>Results: </strong>Of the 76 patients, 52(68.4%) were males and 24(31.6%) were females. The median age of patients was 58 years (IQR: 16). Tumours were predominantly on the right side 44(57.9%) and lower pole 36(47.4%), with a median tumour size of 2.35 cm (IQR: 1.0 cm), and renal score had a median of 5.00 (IQR: 2). Of the total, 70(92.1%) patients underwent open surgery, with complications in 6(7.9%), which were associated significantly with higher body mass index, American Society of Anaesthesiologists classification score, warm ischaemia time and tumour size (p<0.05). Recurrence correlated with tumour size and positive margins (p<0.05). Survival analysis showed a median diseasefree survival (DFS) of 30 months (IQR: 6 months). However, due to the absence of events, the median overall survival (OS) and survival estimates could not be fully calculated. The longest follow-up time was 36 months, with no recorded mortality in the cohort.</p><p><strong>Conclusions: </strong>For individuals with comparatively small localised renal tumours, the selection of partial nephrectomy was found to be a suitable alternative, showcasing exceptional results regarding the complication profile, recurrencefree survival and overall survival.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 1","pages":"56-60"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}