Journal of the Pakistan Medical Association最新文献_第9页

Fabrication of a cell irradiation technique by alpha-particles using allyl diglycol carbonate (ADC) detector and micro-capillary tubes. 利用碳酸二乙二醇烯丙酯（ADC）检测器和微型毛细管制造阿尔法粒子细胞辐照技术。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA-BAGH-16-91

Runas Yakup Sula, Asaad Hamid Ismail

{"title":"Fabrication of a cell irradiation technique by alpha-particles using allyl diglycol carbonate (ADC) detector and micro-capillary tubes.","authors":"Runas Yakup Sula, Asaad Hamid Ismail","doi":"10.47391/JPMA-BAGH-16-91","DOIUrl":"https://doi.org/10.47391/JPMA-BAGH-16-91","url":null,"abstract":"Objective: To study the impact of micro-alpha irradiation collimator with a specific design to irradiate specific normal or up-normal cells using capillary tubes and nuclear track detector type CR-39.Methods: The in vitro experimental study was conducted at radiobiology Lab, of the Physics department, Salahaddin University, Erbil, Iraq from February to April 2022. Several alpha irradiation collimators were calibrated using allyl diglycol carbonate to fabricate a suitable blood cell irradiation technique. Time of irradiation and alpha particle energy were calibrated. Healthy blood samples of Albino rats and cancer blood samples were used to assess the applicability of the fabricated cell irradiation technique. The Rats were divided into intervention and control groups. Data was analysed using SPSS software version 28.Results: Of the 15 healthy, male Albino rats having a mean weight of 230±12g each, there were 12(80%) in the intervention group and 3(20%) in the control group. Microcapillary tubes with suitable diameters had high stability for deposition of a sufficient density of alpha particles on the surface of allyl diglycol carbonate and blood samples. The optimum time of irradiation that had a significant (p<0.05) effect was 20 sec corresponding to alpha energy 4.5MeV.Conclusions: Low irradiation time had significant impact of alpha particles on the average percentage of lymphocyte and neutrophil cells.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 10 (Supple-8)","pages":"S402-S405"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of age and gender on oral health impact profile among dental implant patients in alkarkh district in Baghdad / Iraq: cross-sectional study. 伊拉克巴格达 alkarkh 区种植牙患者年龄和性别对口腔健康影响概况的影响：横断面研究。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA-BAGH-16-58

Modar Abdul Abbas Fedik, Ban Sahib Diab

{"title":"Influence of age and gender on oral health impact profile among dental implant patients in alkarkh district in Baghdad / Iraq: cross-sectional study.","authors":"Modar Abdul Abbas Fedik, Ban Sahib Diab","doi":"10.47391/JPMA-BAGH-16-58","DOIUrl":"https://doi.org/10.47391/JPMA-BAGH-16-58","url":null,"abstract":"Objective: To evaluate the age and gender influence on the quality of life of patients with a dental implant.Methods: The cross-sectional study was conducted from February to April 2022 at Al-Mammon Specialised Dental Centre in the Al-Karkh sector of Baghdad, Iraq, and comprised healthy adult subjects of either gender who had dental implant treatment in the preceding 2 years and their dental implant was in place for at least 6 months. . Data was collected using the Oral Health Impact Profile Questionnaire to measure oral health quality of life. Data was analysed using SPSS 22.Results: Of the 103 subjects, 55(53.4%) were females and 48(46.6%) were males. There were 41(39.81%) subjects aged 18-37 years, 42(40.78%) aged 37-56 years and 20(19.42%) aged 57-74 years. Of the total, 50(48.5%) subjects had moderate health quality, followed by 26(25.24%) low and 27(26.21%) high. There was a significant association of age and gender on the quality of life (p<0.05).Conclusions: Age and gender were found to be important factors influencing the quality of life of dental implant patients.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 10 (Supple-8)","pages":"S259-S261"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pre and postnatal effect of maternal environmental tobacco smoke exposure on infant's growth parameters. 母体环境烟草烟雾暴露对婴儿生长参数的产前和产后影响

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA-BAGH-16-17

Nada Ziyad Salim, Ban Sahib Diab

{"title":"Pre and postnatal effect of maternal environmental tobacco smoke exposure on infant's growth parameters.","authors":"Nada Ziyad Salim, Ban Sahib Diab","doi":"10.47391/JPMA-BAGH-16-17","DOIUrl":"10.47391/JPMA-BAGH-16-17","url":null,"abstract":"Objective: To determine the association between environmental tobacco smoke exposure and growth parameters of infants.Methods: The observational, comparative study was done in rural areas of the Al-Karkh sector of Baghdad, Iraq, from December 2021 to March 2022 after approval from the ethics review committee of the College of Dentistry, University of Baghdad, and comprised mothers aged 20-35 years having infants aged up to one year. Those exposed to environmental tobacco smoke were in group A, while non-exposed mothers were in group B. Along with sociodemographic data, a second-hand smoke exposure scale was used. Weight-for-height, height-for-age and weightfor- age indices, as well as head circumference values, were used to measure growth parameters. Data was analysed using SPSS 22.Results: Of the 150 mothers, 67(44.7%) were in group A with mean age 27.8±4.7 years and 83(55.3%) were in group B with mean age 26,1±4.6 years. The mean age of the children was 9.4±3.1 years in group A and 9.2±2.3 years in group B. Husband was the primary source of smoking at home 55(82.08%). When it came to exposure duration, 58(86.57%) had been exposed for years and 9(13.43 %) for months. The mean Z-score for all growth measurements was higher in group B infants compared to group A (p<0.05) except weight-for-height (p>0.05).Conclusions: Mothers' exposure to environmental tobacco smoke was found to have a significant harmful effect on the growth parameters of infants.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 10 (Supple-8)","pages":"S72-S75"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of mechanical vs. chemomechanical methods in removing intracanal calcium hydroxide medication: a randomised trial. 机械方法与化学机械方法清除牙槽骨内氢氧化钙药物的效果：随机试验。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA.10990

Nehal Amir, Nouman Noor

{"title":"Effectiveness of mechanical vs. chemomechanical methods in removing intracanal calcium hydroxide medication: a randomised trial.","authors":"Nehal Amir, Nouman Noor","doi":"10.47391/JPMA.10990","DOIUrl":"10.47391/JPMA.10990","url":null,"abstract":"Objective: To compare the mechanical and chemomechanical methods for removing calcium hydroxide medication from the root canal system.Methods: The triple-blind, randomised clinical trial was conducted at the Department of Operative Dentistry and Endodontics, School of Dentistry, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan, from December 16, 2022, to June 15, 2023, and comprised patients having necrotic teeth and chronic apical pathosis. They were randomised into groups A and B. On the initial visit, after access opening and chemomechanical preparation, calcium hydroxide paste was placed as an intracanal medication in both groups. the patients were recalled after two weeks. In Group A, calcium hydroxide was removed from the canals using a rotary master apical file, while in Group B, an endoactivator was used to sonically agitate the endodontic irrigant. Verification of placement was done by using a periapical radiograph. Data was analysed using SPSS 26.Results: Of the 98 individuals assessed initially, 60(61.22%) were included; 34(57%) females and 26(43%) males with age ranging from 19 to 57 years. There were 27(45%) incisors, 22(36.7%) premolars and 11(18.3%) canines. There were 30(50%) patients in each of the 2 groups. The intergroup difference was not statistically significant (p=0.43). Tooth arch did not significantly correlate with the removal method (p=0.79).Conclusions: Both methods were found to be equally effective in removing water-based calcium hydroxide medication from the endodontic system.Clinical trial number: NCT05744661.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 10","pages":"1749-1754"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pheochromocytoma-induced congestive heart failure and hypertension in a 21- year-old man-a Case Report. 一名 21 岁男子嗜铬细胞瘤引发的充血性心力衰竭和高血压--病例报告。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA.10839

Shuoxian Chen, Yufeng Chen, Pingan Chen

引用次数: 0

Treating a patient with pan-resistant Acinetobacter: a case study. 治疗泛耐药醋酸杆菌患者：病例研究。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA.10688

Maimoona Nazar, Nasir Ashraf, Laiba Sultan, Laiba Sultan

{"title":"Treating a patient with pan-resistant Acinetobacter: a case study.","authors":"Maimoona Nazar, Nasir Ashraf, Laiba Sultan, Laiba Sultan","doi":"10.47391/JPMA.10688","DOIUrl":"https://doi.org/10.47391/JPMA.10688","url":null,"abstract":"Acinetobacter has emerged as a highly important organism in global healthcare, owing to its propensity to develop pan-resistance. This resistant pathogen poses a significant challenge to healthcare professionals because it not only restricts patient care through ineffective treatment modalities but also leads to high mortality and morbidity rates. The case of a 22-year-old young man reporting to the Emergency department (ER) of Pakistan Institute of Medical Sciences (PIMS), Islamabad, on 6th June, 2023 is presented. He complained of fever accompanied with seizures which gave a suspicion of autoimmune encephalitis or viral haemorrhagic fever. Despite initial therapeutic interventions, the patient's condition worsened, prompting further investigations. Culture and sensitivity testing of tracheal secretions revealed pan-resistance, and subsequent treatment with a combination of antibiotics including Tigecycline and Colistin, yielded a favourable response. The aim for reporting this case, is to highlight the challenges inherent in diagnosing and managing patients with pan-resistant Acinetobacter, as antimicrobial resistance continues to evolve. Furthermore, research endeavours should focus on identifying safe and effective antibiotic combinations, exploring novel treatment approaches, and improving patient outcomes.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 10","pages":"1902-1904"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparative study of 589 and 532 nm low level laser irradiation effects on normal human peripheral blood mononuclear cells viability. 589 纳米和 532 纳米低强度激光照射对正常人外周血单核细胞活力影响的比较研究。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA-BAGH-16-60

Fatimah Saeed Awad, Mustafa Salih Al Musawi, Saba Fawzi Salih

{"title":"A comparative study of 589 and 532 nm low level laser irradiation effects on normal human peripheral blood mononuclear cells viability.","authors":"Fatimah Saeed Awad, Mustafa Salih Al Musawi, Saba Fawzi Salih","doi":"10.47391/JPMA-BAGH-16-60","DOIUrl":"https://doi.org/10.47391/JPMA-BAGH-16-60","url":null,"abstract":"Objective: To assess how laser light affects blood lymphocyte viability in vitro.Methods: The comparative study was conducted from November 2021 to April 2022 at the Department of Medical Physics, Mustansiriyah University, Baghdad, Iraq, and comprised blood samples collected from healthy adults with no medical history of major illnesses or history of taking medications for major diseases.Low-level laser 589nm and 532nm was used at 30 J/cm², 50 J/cm² and 70J/cm² energy intensities and three different post-exposure time; immediately, 1h and 2h after radiation exposure. The viability of normal human lymphocytic cells of the blood was noted. Data was analysed using SPSS 24.Results: The blood samples were drawn from 6 adult male voluteers. The percentage of cells that showed apoptosis post-exposure to 589nm laser was significantly lower than that following exposure to 532nm laser (p<0.05). However, the proportion of apoptotic cells was significantly higher following irradiation with 532nm at varying doses than after irradiation with 589nm (p<0.05).Conclusions: A low-level laser could promote and prevent apoptosis in human peripheral blood cells in a dose- and time-dependent manner.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 10 (Supple-8)","pages":"S266-S269"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of prostate cancer radiotherapy using three-dimensional treatment planning technique. 利用三维治疗计划技术评估前列腺癌放疗。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA-BAGH-16-04

Fatima Jassim Mohammad Hassan, Haydar Hamza Obaid Alabedi

{"title":"Assessment of prostate cancer radiotherapy using three-dimensional treatment planning technique.","authors":"Fatima Jassim Mohammad Hassan, Haydar Hamza Obaid Alabedi","doi":"10.47391/JPMA-BAGH-16-04","DOIUrl":"https://doi.org/10.47391/JPMA-BAGH-16-04","url":null,"abstract":"Objective: To assess the available commercial treatment planning system using three-dimensional conformal radiation therapy with respect to treatment for prostate cancer patients.Methods: This is a cross-sectional study was conducted from June 2021 to February 2022 at the Baghdad Centre for Radiation Therapy and Nuclear Medicine, Baghdad, Iraq, and comprised patients with prostate cancer who were treated with 6MV or 10MV energy using three-dimensional conformal radiation therapy technique, and irradiated using a linear accelerator. The patents were divided into three treatment phases. The prescribed dose in Phase I was 5000 centigrade, in Phase II it was 1800 centigrade, and in Phase III it was 600 centigrade. The number of beams used was 5 and 7. Data was analysed using SPSS 24.Results: Out of 35 patients, 10 (28.6%) in phase I, 15 (42.8%) in phase II, and 10 (28.6%) in phase III. The PTV dose of 5 and 7 beams 6MV energy at the centre was higher than at 1mm, 2mm, and 3mm p values = (0.351, 0.013*, 0.076, 0.295), respectively. Dose to the rectum comparing 6MV and 10MV for beams 5, and 7. The dose to the rectum on phase one at 6MV and 10MV was similar for 5 beams (p=0.611) and 7 beams (p=0.778). A significant difference was seen for 7 beams (p-value=0.008). Phase three showed significant variations in rectum dose at 6 MV and 10MV for 5 beams (p=0.0004). For bladder, a significant difference observed between the energies for 5 beams on phase one and three (p-value=<0.00001*, 0.002*), while at 7 beams only phase 3 were significant (p-value=0.041*).Conclusions: The three-dimensional conformal radiation therapy plan with 10MV energy and a higher number of beams gave a higher coverage of dose for prostate tumours and was found to be a safe dose for the rectum and bladder.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 10 (Supple-8)","pages":"S13-S17"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Distribution of radionuclides in the soils and assessment of radiation hazards in AL Najaf, Iraq: A cross sectional analysis. 伊拉克纳杰夫土壤中放射性核素的分布与辐射危害评估：横断面分析。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA-BAGH-16-85

Shaymaa Awad Kadhim, Wafaa Jasim, Shatha Alhous

引用次数: 0

Effect of the exposure period and concentration of aqueous and alcoholic zingiber (Zingiber officinale) extract on the mean of mortality for hydatid cyst's protocolises. 银杏叶水提取物和酒精提取物的暴露期和浓度对包虫死亡率平均值的影响。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-10-01 DOI: 10.47391/JPMA-BAGH-16-88

Noora Dhyaaldain Abed, Waleed Ahmed Hassen, Hala Yaseen Kadhim, Nagham Yasin Al-Bayati

{"title":"Effect of the exposure period and concentration of aqueous and alcoholic zingiber (Zingiber officinale) extract on the mean of mortality for hydatid cyst's protocolises.","authors":"Noora Dhyaaldain Abed, Waleed Ahmed Hassen, Hala Yaseen Kadhim, Nagham Yasin Al-Bayati","doi":"10.47391/JPMA-BAGH-16-88","DOIUrl":"https://doi.org/10.47391/JPMA-BAGH-16-88","url":null,"abstract":"Objective: To determine the anti-protocolises effect of aqueous and alcoholic zingiber extract.Methods: The present experimental study was conducted from 01, July 2021 to 15. December, 2021 at the College of Education for Pure Sciences, Iraq, and comprised 25mg/mL, 50mg/mL, 100mg/mL and 200mg/mL concentrations of both aqueous and alcoholic extracts of zingiber officinale that were prepared and used in vitro on hydatid cyst protocolises with 10min, 20min, 30min, 40min, 50min and 60min exposure times. The data was analysed using statistical package for the social sciences (SPSS) version 10 by using ANOVA and t- test to determine the differences between groups.Results: The concentration of 200mg/ml was more efficient against the protocolises for aqueous extract, while the alcoholic extract was effective at both 100mg/ml and 200mg/ml concentrations. There was a positive relationship of the degree of killing with both exposure time and concentration.Conclusions: Zingiber officinale could be a potential bioactive natural product and its active constituents could be isolated and used as anti-protoscolex without any side effects.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 10 (Supple-8)","pages":"S390-S393"},"PeriodicalIF":0.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142480884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0