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Journal of the Pakistan Medical Association最新文献

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Childhood trauma and psychopathy in emerging adults: the mediating role of family cohesion. 童年创伤与新生成人精神病：家庭凝聚力的中介作用。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.20486
Jun-Wen Tan, Ying-Ying Li, Hang Li
{"title":"Childhood trauma and psychopathy in emerging adults: the mediating role of family cohesion.","authors":"Jun-Wen Tan, Ying-Ying Li, Hang Li","doi":"10.47391/JPMA.20486","DOIUrl":"https://doi.org/10.47391/JPMA.20486","url":null,"abstract":"<p><strong>Objectives: </strong>To identify the mediating role of family cohesion in the relationship between childhood trauma and psychopathy in Chinese emerging adults.</p><p><strong>Methods: </strong>The cross-sectional study was conducted from November 2022 to February 2023 in China, and comprised individuals aged 18-25 years who had experienced childhood maltreatment, like abuse and neglect. Data was collected online through screening for experiences of childhood trauma, psychopathy and family cohesion. Data was analysed using SPSS 22.</p><p><strong>Results: </strong>Of 696 participants, 106(15.2%) were males and 590 (84.8%) were females. The overall mean age was 21.01±1.92 years. A significant positive correlation between childhood trauma and psychopathy (p<0.05), and significant negative correlations between childhood trauma and family cohesion (p<0.05), and between family cohesion and psychopathy (p<0.05) were found. Significant predictive effects between childhood trauma and family cohesion, family cohesion and psychopathy, childhood trauma and psychopathy were identified (p<0.05). Family cohesion partially mediated the relationship between childhood trauma and psychopathy. After controlling family cohesion as a mediator, the predictive effects between childhood trauma and psychopathy were weakened (R2=0.31 to R2=0.24).</p><p><strong>Conclusions: </strong>Childhood traumatic experiences could predict psychopathy, and increasing family cohesion could mediate this relationship, potentially mitigating the impact of childhood trauma and reducing psychopathic symptoms, successfully navigating emerging adults through the transitional phase.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1209-1212"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transforming pulmonary embolism care: advanced catheter techniques in Pakistan: a case report. 转化性肺栓塞治疗：巴基斯坦先进的导管技术：一例报告。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.21147
Fahad Islam, Muhammad Sohaib Arif, Muhammad Imran Ansari, Abdul Hakeem, Jawed Abubaker
{"title":"Transforming pulmonary embolism care: advanced catheter techniques in Pakistan: a case report.","authors":"Fahad Islam, Muhammad Sohaib Arif, Muhammad Imran Ansari, Abdul Hakeem, Jawed Abubaker","doi":"10.47391/JPMA.21147","DOIUrl":"https://doi.org/10.47391/JPMA.21147","url":null,"abstract":"<p><p>Although post-operative acute pulmonary embolism (PE) is relatively rare, it poses a substantial risk of morbidity and mortality. We report the case of a 45-year-old hypertensive woman who presented with acute chest pain and dyspnoea eight days following a hysterectomy. On admission, she was tachycardic, hypotensive, and hypoxic. Transthoracic echocardiography revealed right ventricular dilation, a reduced tricuspid annular plane systolic excursion (TAPSE) of 12 mm, and a positive McConnell sign. Her Computed tomography pulmonary angiography confirmed bilateral pulmonary emboli. Due to a recent major surgery, systemic thrombolysis was contraindicated. Catheter-directed thrombolysis (CDT) was initiated, administering alteplase at 1 mg/hour per catheter. The patient demonstrated rapid clinical improvement, with marked reduction in oxygen and vasopressor support. She was discharged on rivaroxaban and resumed normal activities within one week. This case underscores the efficacy of CDT as a life-saving alternative in high-risk post-operative PE, especially in resourceconstrained settings.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1281-1283"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biohacks And Diabetes: Obstacle Or Opportunity. 生物黑客和糖尿病：障碍还是机遇。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.25-62
Sanjay Kalra, Madhur Verma, Nitin Kapoor
{"title":"Biohacks And Diabetes: Obstacle Or Opportunity.","authors":"Sanjay Kalra, Madhur Verma, Nitin Kapoor","doi":"10.47391/JPMA.25-62","DOIUrl":"https://doi.org/10.47391/JPMA.25-62","url":null,"abstract":"<p><p>This communication describes the concept of biohacking, and relates it to primary diabetes care. Biohacking can be defined as the use of self-developed, informal non evidence based means of managing and monitoring disease, or promoting health. In the context of diabetes care, biohacks may be related to lifestyle, diet, physical activity or spiritual management, pharmacological therapy, or monitoring strategies. These may be an obstacle, as well as an opportunity, for better health care. Empathetic listening and education is the key to incorporating biohacks as allies in the fight against diabetes.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1296-1297"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of idiopathic sudden sensorineural hearing loss with press needle. 压针治疗特发性突发性感音神经性听力损失。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.20232
Feng Qin, Siquan Guo, Xiuwen Yin, Jinbao Guo, Xiaoyu Lu, Jing Ma
{"title":"Treatment of idiopathic sudden sensorineural hearing loss with press needle.","authors":"Feng Qin, Siquan Guo, Xiuwen Yin, Jinbao Guo, Xiaoyu Lu, Jing Ma","doi":"10.47391/JPMA.20232","DOIUrl":"https://doi.org/10.47391/JPMA.20232","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the effects of conventional therapy and press needle combined therapy on idiopathic sudden sensorineural hearing loss.</p><p><strong>Methods: </strong>The retrospective case-control study was conducted from December 2023 to January 2024 at Department of Otorhinolaryngology, Changzhou Third People's Hospital, China, and comprised patients with idiopathic sudden sensorineural hearing loss ISSNHL admitted from September 2021 to November 2023. The patients were divided into control group CON in which conventional therapy was used, and the PN group in which the press needle therapy was given additionally. The groups were compared with respect to clinical effects. Data was analysed using SPSS 20.</p><p><strong>Results: </strong>Of the 297 patents, 143(48%) were in group CON and 154(52%) were in group PN. There was no difference between the groups in terms of age and gender (p>0.05). The PN group showed greater changes in pure-tone audiometric thresholds than the CON group (p<0.05), and the difference was more significant in high-frequency hearing loss patients (p<0.05).</p><p><strong>Conclusions: </strong>The addition of press needle therapy showed better therapeutic recovery in idiopathic sudden sensorineural hearing loss patients compared to the conventional therapy alone.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1199-1203"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neutrophil to lymphocyte ratio (NLR): a road to an inexpensive biomarker for acute exacerbation of COPD. 中性粒细胞与淋巴细胞比率（NLR）：通往COPD急性加重的廉价生物标志物之路。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.30284
Muhammad Hassan, Laiba Noor
{"title":"Neutrophil to lymphocyte ratio (NLR): a road to an inexpensive biomarker for acute exacerbation of COPD.","authors":"Muhammad Hassan, Laiba Noor","doi":"10.47391/JPMA.30284","DOIUrl":"https://doi.org/10.47391/JPMA.30284","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1317"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overexposure to Benzodiazepines: the irony in psychiatric treatment. 过度使用苯二氮卓类药物：精神病治疗中的讽刺。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.22083
Haleema Sadia
{"title":"Overexposure to Benzodiazepines: the irony in psychiatric treatment.","authors":"Haleema Sadia","doi":"10.47391/JPMA.22083","DOIUrl":"https://doi.org/10.47391/JPMA.22083","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1335"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dumper deaths - public health breakdown on Karachi's roads. 倾倒者死亡——卡拉奇道路公共卫生崩溃。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.31452
Masood Ali Shaikh, Syed Muhammad Mubeen
{"title":"Dumper deaths - public health breakdown on Karachi's roads.","authors":"Masood Ali Shaikh, Syed Muhammad Mubeen","doi":"10.47391/JPMA.31452","DOIUrl":"https://doi.org/10.47391/JPMA.31452","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1314-1315"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The rise of superbugs: Confronting antimicrobial resistance in Pakistan. 超级细菌的崛起：在巴基斯坦面对抗菌素耐药性。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.23220
Fatima Ishaq
{"title":"The rise of superbugs: Confronting antimicrobial resistance in Pakistan.","authors":"Fatima Ishaq","doi":"10.47391/JPMA.23220","DOIUrl":"https://doi.org/10.47391/JPMA.23220","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1342"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unveiling success: determinants of a successful haematopoietic stem cell transplant: a case report. 揭示成功：一个成功的造血干细胞移植的决定因素：一个病例报告。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.21537
Tariq Mahmood Satti, Rimsha Jafar, Zoya Habib, Koukab Ejaz, Zulqarnain Arif, Fahad Haider Shah
{"title":"Unveiling success: determinants of a successful haematopoietic stem cell transplant: a case report.","authors":"Tariq Mahmood Satti, Rimsha Jafar, Zoya Habib, Koukab Ejaz, Zulqarnain Arif, Fahad Haider Shah","doi":"10.47391/JPMA.21537","DOIUrl":"https://doi.org/10.47391/JPMA.21537","url":null,"abstract":"<p><p>Patients with beta thalassemia major can make an uneventful and miraculous recovery after bone marrow transplantation despite lacking a sibling donor. The once widely accepted belief that only a transplant received from a sibling or mother would lead to a successful outcome has been challenged by the advent of new approaches and drugs. We present the case of a 15-yearold girl who received stem cells from her father and, despite suffering an attack of acute graft versus host disease (aGVHD) and depression, still managed to achieve a 100% success rate. This report highlights the importance of factors other than the source of stem cells in evaluating the patient's outcome and the lack of awareness about this disease even among the literate population in our country.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1284-1286"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Creeping through the sinuses-unusual intrusion of ascariasis in the nasal cavity of a young female: a case report. 悄悄穿过鼻窦——蛔虫病在年轻女性鼻腔的不寻常侵入：一例报告。
IF 0.8 4区 医学
Journal of the Pakistan Medical Association Pub Date : 2025-08-01 DOI: 10.47391/JPMA.20350
Fariha Sahrish, Sahar Iqbal, Sara Masood Cheema, Saima Irum, Mehwish Niaz, Maira Jabbar Chaudhary
{"title":"Creeping through the sinuses-unusual intrusion of ascariasis in the nasal cavity of a young female: a case report.","authors":"Fariha Sahrish, Sahar Iqbal, Sara Masood Cheema, Saima Irum, Mehwish Niaz, Maira Jabbar Chaudhary","doi":"10.47391/JPMA.20350","DOIUrl":"https://doi.org/10.47391/JPMA.20350","url":null,"abstract":"<p><p>Ascaris lumbricoides, a prevalent nematode affecting humans, frequently infests the gastrointestinal tract but can also be seen in atypical locations such as the middle ear, nose, epiglottis, and maxillary sinuses. Herein, we present the case of a three-year-old baby girl from a rural background, managed at the Department of ENT, Chaudhary Mohammad Akram Teaching& Research Hospital, Lahore. She presented with 15-day history of unilateral nasal blockage and repugnant nasal discharge from the right nostril. A general physical examination showed a vague firm to hard swelling along the right lateral nasal wall, enlarged right maxillary sinus, and infraorbital region. Radiographic imaging confirmed a hazy right maxillary sinus. The nasal cavity contained mortified pale-yellow material, and creamy discharge from the maxillary ostium. Surgical exploration revealed no foreign bodies.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 8","pages":"1271-1273"},"PeriodicalIF":0.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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