Journal of the Pakistan Medical Association最新文献

Beyond Dialysis: Reshaping CKD Paradigms in Developing Nations. 超越透析：发展中国家重塑慢性肾功能衰竭范例。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.11541

Muhammad Tayyab Ijaz, Namra Ijaz

引用次数: 0

Effects of Kabat rehabilitation versus mime therapy on facial disability and synkinesis in patients of Bell's palsy. 卡巴特康复疗法与哑剧疗法对贝尔麻痹患者面部残疾和同步运动的影响。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.11247

Ayesha Amjad, Ayesha Jamil, Nida Fatima, Hira Bano Javaid, Hafsa Zahid

{"title":"Effects of Kabat rehabilitation versus mime therapy on facial disability and synkinesis in patients of Bell's palsy.","authors":"Ayesha Amjad, Ayesha Jamil, Nida Fatima, Hira Bano Javaid, Hafsa Zahid","doi":"10.47391/JPMA.11247","DOIUrl":"https://doi.org/10.47391/JPMA.11247","url":null,"abstract":"Objective: To compare the effects of Kabat rehabilitation and Mime therapy on facial disability and synkinesis in patients with Bell's palsy.Methods: The single-blind, randomised clinical trial was conducted at the Physiotherapy Department of the University of Lahore Teaching Hospital, Lahore, Pakistan, from May to October 2023, and comprised adults of either gender aged 25-50 years having sub-acute or chronic unilateral Bell's palsy of non-congenital origin. The patients were randomised into Kabat rehabilitation group A and mime therapy group B. Conventional physical therapy was given to both groups additionally. Facial disability was assessed using the Facial Disability Index scale, and synkinesis was observed using the House-Brackmann Facial Nerve Grading Scale. Data was analysed using SPSS 25.Results: Of the 72 patients, 41(56.9%) were females and 31(43.1%) were males. The overall mean age was 37.77±6.98 years, mean body mass index was 25.71±5.71kg/m2 and 41(56.9%) patients had left-sided palsy. Facial disability and synkinesis were significantly different in both groups post-intervention (p<0.001), while intergroup differences were significant in the 3rd and 6th weeks (p<0.001).Conclusions: Kabat rehabilitation led to more significant improvements in synkinesis and facial disability compared to mime therapy.Clinical trial number: Clinical trials.gov registration id: NCT06029855.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 11","pages":"1927-1931"},"PeriodicalIF":0.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effectiveness of liver function tests in the prediction of mortality in patients with COVID-19. 肝功能检测在预测 COVID-19 患者死亡率方面的有效性。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.10832

Erdi Huseyin Erdem, Bahar Aydinli, Serkan Dogru, Harun Ozmen

{"title":"The effectiveness of liver function tests in the prediction of mortality in patients with COVID-19.","authors":"Erdi Huseyin Erdem, Bahar Aydinli, Serkan Dogru, Harun Ozmen","doi":"10.47391/JPMA.10832","DOIUrl":"https://doi.org/10.47391/JPMA.10832","url":null,"abstract":"Objectives: To evaluate the impact of liver function test abnormalities on mortality in critically ill coronavirus disease- 2019 patients.Methods: The single-centre, retrospective study was conducted at the Department of Anaesthesiology and Reanimation, Mersin City Training and Research Hospital, Turkiye, and comprised data from March 2020 to January 2022 of patients with positive real-time reverse transcription polymerase chain reaction test on nasopharyngeal swab sample for coronavirus disease-2019. Comorbidities, demographic data, admission to and discharge from the intensive care unit, Acute Physiology and Chronic Health Evaluation II scores, complete blood count on the first and second day of hospitalisation, coagulation parameters, biochemical analysis, 7-day, 28-day and total mortality of the patients in the intensive care unit were recorded. The patients were then divided into groups, with Group 1 having patients with normal liver enzymes, Group 2 having patients with abnormal liver enzymes, and Group 3 having patients with liver damage. Data was analysed using SPSS 20.Results: Of the 940 subjects, 587(62.4) were males and 353(37.6) were females. The overall mean age of the patients was 67.11±16.65 years. There were 395(42%) patients in Group 1, 534(56.8%) in Group 2 and 11(1.2%) in Group 3. Gamma-glutamyl transferase-1s, aspartate aminotransferase-2nd and albumin-2nd were significant predictors of mortality (p<0.05).Conclusion: High gamma-glutamyl transferase, aspartate aminotransferase and low albumin levels in critically ill coronavirus disease-2019 patients could be considered indicators of high mortality rate.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 11","pages":"1953-1958"},"PeriodicalIF":0.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathological pattern in endometrial biopsies in reproductive age group and Post-menopausal women. 育龄期和绝经后妇女子宫内膜活检组织病理学模式。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.11352

Farah Fatima Abbas, Uzma Bukhari, Nehad Khan, Fatima Arshad, Saba Kamil

{"title":"Histopathological pattern in endometrial biopsies in reproductive age group and Post-menopausal women.","authors":"Farah Fatima Abbas, Uzma Bukhari, Nehad Khan, Fatima Arshad, Saba Kamil","doi":"10.47391/JPMA.11352","DOIUrl":"https://doi.org/10.47391/JPMA.11352","url":null,"abstract":"Objectives: To identify and analyse the different types and frequencies of morphological pattern in endometrial biopsies along with their associated diagnoses across different age groups.Methods: The cross-sectional study was conducted at the Histopathology Section of the Dow Diagnostics Reference and Research Laboratory, Dow University Health Sciences, Karachi, from October 2022 to October 2023. Data was obtained from pre-existing medical record of samples of endometrial biopsies. Open Epi sample size calculator is used for the estimation of sample size. The patients were divided into two aged-based groups; reproductive age ≤45 years in group 1 and postmenopause age ≥46 years in group 2. The histological diagnosis was made by a consultant histopathologist.Results: Of the 430 endometrial biopsies 222(51.6%) were in group 1 and 208(48.4%) were in group 2. In both groups, the most common finding was polyps 271(63%). Malignant changes were found in 12(5.7%) group 2 cases compared to 4(1.8%) group 1 cases.Conclusions: The most common endometrial lesion in both age groups was endometrial polyp. Malignant changes were seen more in postmenopausal women compared to those in the reproductive age group.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 11","pages":"1964-1967"},"PeriodicalIF":0.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inspecting the potential of thymol as a therapeutic agent for treating Alzheimer's disease. 研究百里酚作为治疗剂治疗阿尔茨海默病的潜力。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.10718

Muhammad Waleed Imran, Sanwal Sardar Nawaz, Muhammad Moaz

引用次数: 0

Dysregulated renal tubular handling of filtered glucose in patients with type 2 diabetes mellitus: A descriptive study. 2 型糖尿病患者肾小管对过滤葡萄糖的处理失调：一项描述性研究

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.11415

Asim Zulfiqar, Saira Jahan, Muhammad Nadim Akbar Khan, Shamaila Burney, Muhammad Farooq, Kiran Fatima

{"title":"Dysregulated renal tubular handling of filtered glucose in patients with type 2 diabetes mellitus: A descriptive study.","authors":"Asim Zulfiqar, Saira Jahan, Muhammad Nadim Akbar Khan, Shamaila Burney, Muhammad Farooq, Kiran Fatima","doi":"10.47391/JPMA.11415","DOIUrl":"https://doi.org/10.47391/JPMA.11415","url":null,"abstract":"Objective: To determine the frequency of suspected dysregulated renal tubular handling of filtered glucose, and its association with blood glucose levels in type 2 diabetes mellitus.Methods: The analytical, cross-sectional study was conducted from November 2022 to June 2023 at the Department of Medicine along with the Department of Pathology and Biochemistry, Pakistan Railway Hospital, Islamic International Medical College, Rawalpindi, Pakistan, and comprised diabetics aged 19-80 years. Blood and urinary glucose were assessed at the point of contact. Blood glucose 80-180mg/dl was considered glucose in range and >180mg/dl glucose above range. Hyperfunction of sodium glucose transport receptors was suspected if urinary glucose was <++ and the function of these receptors was considered normal if urinary sugar was ++ or more. Association of suspected receptors functioning and their association with blood glucose levels was determined. Data was analysed using SPSS 26.Results: Of the 159 diabetics, 91(57%) were females and 68(43%) were males. The overall mean age was 57±11 years (range: 46-68 years). Of the total, 43(27%) patients had glucose in range and 116(73%) had glucose above range. Of the diabetics with glucose above range, 54(47%) patients had hyper-functioning sodium glucose transport receptors, and 62(53%) had normal functioning sodium glucose transport receptors. Of the patients with glucose in range, 11(26%) had hyperfunctioning sodium glucose transport receptors, and 32(74%) had normal functioning sodium glucose transport receptors. There was a significant association between sodium glucose transport receptors' function and blood glucose levels (p<0.001).Conclusion: Dysfunction of sodium glucose transport receptors affected the secretion of glucose in the urine, resulting in impaired glucose regulation in type 2 diabetes mellitus cases.","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"74 11","pages":"1986-1989"},"PeriodicalIF":0.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142644907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidental Renal Infarction on imaging for Abdominal Aortic Aneurysm. 腹主动脉瘤造影中偶然发现的肾梗塞。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.24-93

Cevdet Donmez, Asma Bitar De Zayas-Enriquez, Hosny Hamza, Humayun Bashir

引用次数: 0

Unforeseen severity in a case of neonatal cow milk protein allergy: A case report. 一例新生儿牛奶蛋白过敏症的意外严重性：病例报告。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.11615

Alizeh Imran, Fatima Mustafa Lakdawala, Shahzaib Khan

引用次数: 0

Exploring the role of ketogenic diet in ADPKD treatment: A promising avenue. 探索生酮饮食在 ADPKD 治疗中的作用：一条充满希望的途径

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.20683

Abdul Mutaal, Dawood Shehzad, Khubaib Samdani

引用次数: 0

Obesity Associated Reproductive and Sexual Syndrome(OARS) in Men. 男性肥胖相关生殖和性综合征（OARS）。

IF 0.8 4区医学

Journal of the Pakistan Medical Association Pub Date : 2024-11-01 DOI: 10.47391/JPMA.24-91

Sanjay Kalra, Atul Dhingra, Nitin Kapoor

引用次数: 0