Mahwish Noor-Ul-Haq, Muhammad Azam, Muhammad Sharif, Sadaf Zafarullah, Babar Shahzad, Muhammad Rehman Waheed
{"title":"Hernia uterus inguinale in a two months old female infant.","authors":"Mahwish Noor-Ul-Haq, Muhammad Azam, Muhammad Sharif, Sadaf Zafarullah, Babar Shahzad, Muhammad Rehman Waheed","doi":"10.47391/JPMA.21264","DOIUrl":"https://doi.org/10.47391/JPMA.21264","url":null,"abstract":"<p><p>The most common age groups for indirect inguinal hernias are infants, with a low prevalence in girls. It is very uncommon for uterus, ovaries and fallopian tubes to be present in hernial sac altogether. Since strangulation and necrosis of these organs may result in serious illness and infertility, early detection and surgery are essential. The most useful technique for diagnosing and differentiating infant inguinal hernias is ultrasound. We sought to illustrate surgical features of a two months old female infant, delivered by caesarean section, presented to the Paediatric Surgery Emergency Department at Mayo Hospital Lahore on 8th March 2024 with irreducible mass in left groin. The diagnosis was made via ultrasound, which revealed an indirect incarcerated inguinal hernia containing viable uterus, ovaries and fallopian tubes. Surgery was performed through an inguinal approach, where the uterus, fallopian tubes and ovaries were found within the hernial sac. High ligation and additional repair of internal inguinal ring were done after reducing the contents in the peritoneal cavity. The postoperative course was uneventful.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"495-497"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Potential for Nirsevimab use in Pakistan.","authors":"Muhammad Moaz, Basum Hayat","doi":"10.47391/JPMA.20282","DOIUrl":"https://doi.org/10.47391/JPMA.20282","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"528"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of chemotherapy on cognitive functioning and quality of life among cancer patients in Peshawar.","authors":"Summaiya Arif","doi":"10.47391/JPMA.10319","DOIUrl":"https://doi.org/10.47391/JPMA.10319","url":null,"abstract":"<p><p>The time series study was planned to assess the possible effects of chemotherapy and radiotherapy on cognitive functioning and patients' quality of life. Conducted at the Institute of Radiotherapy and Nuclear Medicine Hospital, Peshawar, Pakistan, from 1st January, 2021 to 15th April, 2021, the study comprised 60 patients who were divided into chemotherapy, radiotherapy, and healthy control groups. Data was collected using the Functional Assessment of Cancer Therapy-cognitive questionnaire and the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30. Chemotherapy significantly affected the cognitive functioning of participants compared to the other groups (p<0.05). The quality of life of the patients in chemotherapy and radiotherapy groups was significantly impaired compared to the controls (p<0.05). The findings showed the negative side effects of chemotherapy and radiotherapy.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"476-479"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adrenal Asthenia.","authors":"Sanjay Kalra, Atul Dhingra, Nitin Kapoor","doi":"10.47391/JPMA.25-18","DOIUrl":"https://doi.org/10.47391/JPMA.25-18","url":null,"abstract":"<p><p>The terms 'adrenal asthenia', 'adrenal fatigue' and 'adrenal burnout', sometimes used in lay language, are not a part of the medical or endocrine lexicon. In this opinion piece, we explore the relevance of adrenal asthenia and describe how it can be used in different clinical situations, with varying connotations. Adrenal asthenia may refer to adrenocortical insufficiency, increased parasympathetic or reduced adrenergic tone, or fatigue due to excessive and continuous exposure to stress. It may be mediated by hypoglycaemia or dyselectrolytaemia. The term adrenal asthenia has important clinical and public health advantages.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"498-500"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel advances in chronic obstructive pulmonary disease treatment: Ensifentrine.","authors":"Aamrah Wakil, Taha Ahmad Siddiqui, Eesha Arshad","doi":"10.47391/JPMA.21488","DOIUrl":"https://doi.org/10.47391/JPMA.21488","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"523"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatema Ali Lanewala, Akhtar Jamal Khan, Mirza Naqi Zafar, Tahir Aziz
{"title":"Frequency, associated factors and outcome of raised intraocular pressure in live-related renal transplant recipients: A single-centre experience.","authors":"Fatema Ali Lanewala, Akhtar Jamal Khan, Mirza Naqi Zafar, Tahir Aziz","doi":"10.47391/JPMA.21710","DOIUrl":"https://doi.org/10.47391/JPMA.21710","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the frequency, associated factors and outcomes of elevated intraocular pressure in live-related renal transplant recipients.</p><p><strong>Methods: </strong>The study was conducted at the Department of Ophthalmology, Sindh Institute of Urology and Transplantation, Karachi, in 2023. The data was divided into group A cases having intraocular pressure ≥23mmHg and group B controls having intraocular pressure <23mmHg. The groups were compared for factors such as immunosuppression medications, acute rejection episodes, human leukocyte antigen match, duration of dialysis before transplant, and pre-existing microvascular diseases. Data was analysed using SPSS 22.</p><p><strong>Results: </strong>Of the 2,738 patients screened, 131(4.8%) exhibited intraocular pressure ≥23mmHg. Intergroup comparison between group A and group B showed no significant relationship of intraocular pressure increase with cyclosporine, tacrolimus and everolimus (p>0.05). Azathioprine demonstrated significant association with intraocular pressure elevation at the time of measuring intraocular pressure (p<0.05). Mycophenolate mofetil showed an association with IOP only when assessed as initial immunesuppression at the time of transplantation (p<0.05). At the time of IOP assessment, MMF was not found to be a significant factor responsible for IOP elevation (p>0.05). Patients who had received Antithymocyte globulin (ATG) were found to have remarkable association with raised IOP. No significant link was noted between hypertension, dialysis duration and human leukocyte antigen match (p>0.05). The multivariate analysis showed that Azathioprine was the only factor associated with raised IOP at the time of assessment (p<0.001).</p><p><strong>Conclusions: </strong>There was a potential risk of medication side effects, including secondary glaucoma, among renal transplant recipients.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"451-455"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143721691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Motivational Therapeutics and Medicine.","authors":"Sanjay Kalra, Suneet Kumar Verma, Nitin Kapoor","doi":"10.47391/JPMA.25-25","DOIUrl":"https://doi.org/10.47391/JPMA.25-25","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"376-377"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rohma Malik, Urwa Ashfaq, Beshair Aziz, Allahdad Khan, Ayesha Zafar, Muhammad Farhan Jamil
{"title":"Reason for joining the medical profession: Passion or parental pressure.","authors":"Rohma Malik, Urwa Ashfaq, Beshair Aziz, Allahdad Khan, Ayesha Zafar, Muhammad Farhan Jamil","doi":"10.47391/JPMA.20903","DOIUrl":"https://doi.org/10.47391/JPMA.20903","url":null,"abstract":"<p><strong>Objective: </strong>To determine the factors that influence medical students' decision to pursue a career in medicine, and to assess their level of satisfaction with their decision.</p><p><strong>Methods: </strong>The descriptive, cross-sectional study was conducted at the Nishtar Medical University, Multan, Pakistan, from July to October 2023, and comprised first year medical students of the 2023-24 academic session. Data was collected using a questionnaire-based survey form. Data was analysed using SPSS 23.</p><p><strong>Results: </strong>Of the 174 students with mean age 20.1±1.4 years, 93(53.4%) were males with mean age 19.9±1.5 years, and 81(46.6%) were females with mean age 20.3±1.2 years (p>0.05). For 121(69.5%) students, 'parental pressure' was the primary factor, followed by 'passion' for 41(23.6%), 'inspired by others' 3(1.7%), 'noble profession' 2(1.1%), 'monetary gains' 3(1.7%) and 'just by chance' 4(2.3%). There were 26(14.9%) subjects who had conducted thorough research before deciding to pursue the profession. For 85(48.9%) students, personal interest played a minor role in career selection. Overall, 88(50.6%) students were completely satisfied with the decision, 12(6.9%) had concerns, and 74(42.5%) were dissatisfied.</p><p><strong>Conclusions: </strong>A significant number of students entered the medical profession under parental pressure. Only about half of the students were satisfied with their decision.</p>","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"525-527"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bacteriophage therapy: A potentially effective tool in combatting tooth decay.","authors":"Mehwash Kashif, Aman Ashar","doi":"10.47391/JPMA.25-17","DOIUrl":"https://doi.org/10.47391/JPMA.25-17","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"374-375"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Empowering independence: the role of occupational therapy in overcoming life challenges.","authors":"Sadia Saleem, Khadija Saleem, Sabeen Masood, Faiza Yousaf, Laiba Saleem","doi":"10.47391/JPMA.21022","DOIUrl":"https://doi.org/10.47391/JPMA.21022","url":null,"abstract":"","PeriodicalId":54369,"journal":{"name":"Journal of the Pakistan Medical Association","volume":"75 3","pages":"518-519"},"PeriodicalIF":0.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}