{"title":"Twenty-eight years of GM Food and feed without harm: why not accept them?","authors":"Richard E Goodman","doi":"10.1080/21645698.2024.2305944","DOIUrl":"10.1080/21645698.2024.2305944","url":null,"abstract":"<p><p>Since the first genetically engineered or modified crops or organisms (GMO) were approved for commercial production in 1995, no new GMO has been proven to be a hazard or cause harm to human consumers. These modifications have improved crop efficiency, reduced losses to insect pests, reduced losses to viral and microbial plant pathogens and improved drought tolerance. A few have focused on nutritional improvements producing beta carotene in Golden Rice. Regulators in the United States and countries signing the CODEX Alimentarius and Cartagena Biosafety agreements have evaluated human and animal food safety considering potential risks of allergenicity, toxicity, nutritional and anti-nutritional risks. They consider risks for non-target organisms and the environment. There are no cases where post-market surveillance has uncovered harm to consumers or the environment including potential transfer of DNA from the GMO to non-target organisms. In fact, many GMOs have helped improve production, yield and reduced risks from chemical insecticides or fungicides. Yet there are generic calls to label foods containing any genetic modification as a GMO and refusing to allow GM events to be labeled as organic. Many African countries have accepted the Cartagena Protocol as a tool to keep GM events out of their countries while facing food insecurity. The rationale for those restrictions are not rational. Other issues related to genetic diversity, seed production and environmental safety must be addressed. What can be done to increase acceptance of safe and nutritious foods as the population increases, land for cultivation is reduced and energy costs soar?</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":"15 1","pages":"40-50"},"PeriodicalIF":3.9,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10939142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140112193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Growing knowledge impact of gene-editing technology on public acceptance: a longitudinal analysis in Japan.","authors":"Atsushi Sato, Daiki Watanabe, Yoko Saito","doi":"10.1080/21645698.2024.2435709","DOIUrl":"10.1080/21645698.2024.2435709","url":null,"abstract":"<p><p>Genome editing (GE) technology holds significant promise for advancements in crop development and medical applications. However, public acceptance of GE in Japan remains uncertain. This study aimed to examine how knowledge impacts public acceptance of GE technology, focusing on differences across diffusion stages and application purposes. Using ordinary least squares regression on repeated survey data collected from 2018 to 2023 in Japan (<i>n</i> = 6,234), we investigated the influence of knowledge on support for GE in consumer benefits, producer benefits, and medical technology. Our findings revealed that the effect of knowledge on technology acceptance has strengthened over time. Consumers with greater knowledge of GE are increasingly supportive of its advancement, emphasizing the growing importance of information as the technology becomes more widespread. This research highlights the role of transparent policy discussions in fostering public trust and support, thereby promoting the successful integration of new technologies into society.</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":"15 1","pages":"411-428"},"PeriodicalIF":4.5,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11633139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Gene editing achieves consistently higher favorability in social and traditional media than GMOs.","authors":"Mark Lynas, Selene Adams, Karen Stockert","doi":"10.1080/21645698.2023.2226889","DOIUrl":"10.1080/21645698.2023.2226889","url":null,"abstract":"<p><p>While GMOs have been the subject of negative discourse over a long time period, it is possible that newer breeding technologies like gene editing are viewed more favorably. We present data for a 5-year period between January 2018 and December 2022, showing that in content specific to agricultural biotechnology, gene editing achieves consistently higher favorability ratings than GMOs in both social and traditional English-language media. Our sentiment analysis shows that favorability is especially positive in social media, with close to 100% favorability achieved in numerous monthly values throughout our 5 years of analysis. We believe that the scientific community can therefore be cautiously optimistic based on current trends that gene editing will be accepted by the public and be able to achieve its promise of making a substantial contribution to future food security and environmental sustainability worldwide. However, there are some recent indications of more sustained downward trends, which may be a cause for concern.</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":" ","pages":"1-8"},"PeriodicalIF":3.9,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10042924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modification of Fatty Acid Profile and Oil Contents Using Gene Editing in Oilseed Crops for a Changing Climate.","authors":"Saeed Rauf, Seerat Fatima, Rodomiro Ortiz","doi":"10.1080/21645698.2023.2243041","DOIUrl":"10.1080/21645698.2023.2243041","url":null,"abstract":"<p><p>Mutation breeding based on various chemical and physical mutagens induces and disrupts non-target loci. Hence, large populations were required for visual screening, but desired plants were rare and it was a further laborious task to identify desirable mutants. Generated mutant had high defect due to non-targeted mutation, with poor agronomic performance. Mutation techniques were augmented by targeted induced local lesions in genome (TILLING) facilitating the selection of desirable germplasm. On the other hand, gene editing through CRISPR/Cas9 allows knocking down genes for site-directed mutation. This handy technique has been exploited for the modification of fatty acid profile. High oleic acid genetic stocks were obtained in a broad range of crops. Moreover, genes involved in the accumulation of undesirable seed components such as starch, polysaccharide, and flavors were knocked down to enhance seed quality, which helps to improve oil contents and reduces the anti-nutritional component.</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":" ","pages":"1-12"},"PeriodicalIF":3.9,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10326468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer A Anderson, James Mickelson, Brandon J Fast, Nathan Smith, Robert C Pauli, Carl Walker
{"title":"Genetically modified DP915635 maize is agronomically and compositionally comparable to non-genetically modified maize.","authors":"Jennifer A Anderson, James Mickelson, Brandon J Fast, Nathan Smith, Robert C Pauli, Carl Walker","doi":"10.1080/21645698.2023.2208997","DOIUrl":"10.1080/21645698.2023.2208997","url":null,"abstract":"<p><p>DP915635 maize was genetically modified (GM) to express the IPD079Ea protein for corn rootworm (Diabrotica spp.) control. DP915635 maize also expresses the phosphinothricin acetyltransferase (PAT) protein for tolerance to glufosinate herbicide and the phosphomannose isomerase (PMI) protein that was used as a selectable marker. A field study was conducted at ten sites in the United States and Canada during the 2019 growing season. Of the 11 agronomic endpoints that were evaluated, two of them (early stand count and days to flowering) were statistically significant compared with the control maize based on unadjusted p-values; however, these differences were not significant after FDR-adjustment of p-values. Composition analytes from DP915635 maize grain and forage (proximates, fiber, minerals, amino acids, fatty acids, vitamins, anti-nutrients, and secondary metabolites) were compared to non-GM near-isoline control maize (control maize) and non-GM commercial maize (reference maize). Statistically significant differences were observed for 7 of the 79 compositional analytes (16:1 palmitoleic acid, 18:0 stearic acid, 18:1 oleic acid, 18:2 linoleic acid, 24:0 lignoceric acid, methionine, and α-tocopherol); however, these differences were not significant after FDR-adjustment. Additionally, all of the values for composition analytes fell within the range of natural variation established from the in-study reference range, literature range, and/or tolerance interval. These results demonstrate that DP915635 is agronomically and compositionally comparable to non-GM maize represented by non-GM near-isoline control maize and non-GM commercial maize.</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":"14 1","pages":"1-8"},"PeriodicalIF":4.5,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10161957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9792625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Deconstruction of science hegemony: discursive strategies of Chinese science communication on genetically modified foods.","authors":"Jinrong Lin","doi":"10.1080/21645698.2023.2247133","DOIUrl":"10.1080/21645698.2023.2247133","url":null,"abstract":"<p><p>This study analyzes Chinese online science communication and discussion about genetically modified foods (GMFs). Based on data collected from one of the largest Chinese GMFs science popularization website, it utilizes Wodak's discourse analysis to investigate how Chinese genetically modified (GM) scientific discourse is characterized by a range of discursive strategies that construct specific identity of Chinese GM scientists and explore science hegemony underlying Chinese GMFs debates. Findings show that discourse features of Chinese GM scientific discourse is objective as well as emotional, particularly conveying a strong sense of superiority realized by trope, argumentative strategies and intertextuality. The unequal power relationship between scientists and the public as well as Chinese intellectuals' knowledge hegemony could partly explain why those discursive strategies are employed in science communication practices of GMFs debates in Chinese context.</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":" ","pages":"1-9"},"PeriodicalIF":3.9,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10406276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Processes for regulating genetically modified and gene edited plants.","authors":"John R Caradus","doi":"10.1080/21645698.2023.2252947","DOIUrl":"10.1080/21645698.2023.2252947","url":null,"abstract":"<p><p>Innovation in agriculture has been essential in improving productivity of crops and forages to support a growing population, improving living standards while contributing toward maintaining environment integrity, human health, and wellbeing through provision of more nutritious, varied, and abundant food sources. A crucial part of that innovation has involved a range of techniques for both expanding and exploiting the genetic potential of plants. However, some techniques used for generating new variation for plant breeders to exploit are deemed higher risk than others despite end products of both processes at times being for all intents and purposes identical for the benefits they provide. As a result, public concerns often triggered by poor communication from innovators, resulting in mistrust and suspicion has, in turn, caused the development of a range of regulatory systems. The logic and motivations for modes of regulation used are reviewed and how the benefits from use of these technologies can be delivered more efficiently and effectively is discussed.</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":" ","pages":"1-41"},"PeriodicalIF":3.9,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761188/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10192871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"U.S. consumer support for genetically modified foods: Time trends and assessments of four GM attributes.","authors":"Jane Kolodinsky, Nick Rose, Julia Danielsen","doi":"10.1080/21645698.2023.2278683","DOIUrl":"10.1080/21645698.2023.2278683","url":null,"abstract":"<p><p>There is a large literature about consumer acceptance of GM foods dating back almost three decades, but there are fewer studies that investigate how support for specific GM attributes contribute to general support for novel plant technologies. In addition, there is little information on how support has changed over time. Using survey data from 2018 to 2023 in a U.S. State (Vermont) (<i>n</i> = 3101), we analyze changes in support for a variety of GM attributes over time. There are three major findings. First, there is movement toward neutrality in support for various GM attributes, but opposition continues. Second, there is variability in support for different GM attributes. People are most supportive (least opposed) to GM attributes that improve flora (plant health or drought tolerance), and most opposed (least supportive) of attributes that impact fauna (specifically fish). Third, multivariate regression reveals that assessments of individual GM attributes contribute to levels of overall support of the use of GM technologies in agricultural production.</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":"14 1","pages":"1-13"},"PeriodicalIF":3.9,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DNA-free genome editing for <i>ZmPLA1</i> gene via targeting immature embryos in tropical maize.","authors":"Sagar Krushnaji Rangari, Manjot Kaur Sudha, Harjot Kaur, Nidhi Uppal, Gagandeep Singh, Yogesh Vikal, Priti Sharma","doi":"10.1080/21645698.2023.2197303","DOIUrl":"10.1080/21645698.2023.2197303","url":null,"abstract":"<p><p>Doubled haploid (DH) production accelerates the development of homozygous lines in a single generation. In maize, haploids are widely produced by the use of haploid inducer Stock 6, earlier reported in 1959. Three independent studies reported haploid induction in maize which is triggered due to a 4 bp frame-shift mutation in <i>matrilineal</i> (<i>ZmPLA1</i>) gene. The present study was focused on the generation of mutants for <i>ZmPLA1</i> gene in maize inbred line LM13 through site-directed mutagenesis via CRISPR/Cas9-mediated ribonucleoprotein (RNP) complex method to increase the haploid induction rate. Three single guide RNAs (sgRNAs) for the <i>ZmPLA1</i> gene locus were used for transforming the 14 days old immature embryos via bombardment. 373 regenerated plants were subjected to mutation detection followed by Sanger's sequencing. Out of three putative mutants identified, one mutant depicted one base pair substitution and one base pair deletion at the target site.</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":" ","pages":"1-7"},"PeriodicalIF":3.9,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10761150/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9254178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CRISPR/Cas9-gene editing approaches in plant breeding.","authors":"Himanshu Saini, Rajneesh Thakur, Rubina Gill, Kalpana Tyagi, Manika Goswami","doi":"10.1080/21645698.2023.2256930","DOIUrl":"10.1080/21645698.2023.2256930","url":null,"abstract":"<p><p>CRISPR/Cas9 gene editing system is recently developed robust genome editing technology for accelerating plant breeding. Various modifications of this editing system have been established for adaptability in plant varieties as well as for its improved efficiency and portability. This review provides an in-depth look at the various strategies for synthesizing gRNAs for efficient delivery in plant cells, including chemical synthesis and <i>in vitro</i> transcription. It also covers traditional analytical tools and emerging developments in detection methods to analyze CRISPR/Cas9 mediated mutation in plant breeding. Additionally, the review outlines the various analytical tools which are used to detect and analyze CRISPR/Cas9 mediated mutations, such as next-generation sequencing, restriction enzyme analysis, and southern blotting. Finally, the review discusses emerging detection methods, including digital PCR and qPCR. Hence, CRISPR/Cas9 has great potential for transforming agriculture and opening avenues for new advancements in the system for gene editing in plants.</p>","PeriodicalId":54282,"journal":{"name":"Gm Crops & Food-Biotechnology in Agriculture and the Food Chain","volume":"14 1","pages":"1-17"},"PeriodicalIF":4.5,"publicationDate":"2023-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10512805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41177475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}