npj Microgravity最新文献_第2页

Implied gravity promotes coherent motion perception. 隐含重力促进连贯运动感知。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-07-07 DOI: 10.1038/s41526-025-00498-5

Xiqian Lu, Bogeng Song, Shaoshuai Zhang, Shujia Zhang, Mei Huang, Ying Wang, Yi Jiang

{"title":"Implied gravity promotes coherent motion perception.","authors":"Xiqian Lu, Bogeng Song, Shaoshuai Zhang, Shujia Zhang, Mei Huang, Ying Wang, Yi Jiang","doi":"10.1038/s41526-025-00498-5","DOIUrl":"10.1038/s41526-025-00498-5","url":null,"abstract":"Gravity, a constant in Earth's environment, constrains not only physical motion but also our estimation of motion trajectories. Early studies show that natural gravitational acceleration facilitates the manual interception of free-falling objects. However, whether implied gravity affects the perception of coherent motion patterns from local motion cues remains poorly understood. Here, we designed a motion coherence threshold task to measure the visual discrimination of coherent global motion with natural (1 g) and reversed (-1 g) gravitational accelerations. Across five experiments, we showed that the perceptual thresholds of motion coherence were significantly lower under the natural gravity than the reversed gravity condition, regardless of variations in stimulus parameters and visual contexts. These convergent results suggest that the human visual system inherently extracts the gravitational acceleration cues conveyed by local motion signals and integrates them into a unified global motion, thereby facilitating the visual perception of complex motion patterns in natural environments.","PeriodicalId":54263,"journal":{"name":"npj Microgravity","volume":"11 1","pages":"36"},"PeriodicalIF":4.4,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12234745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144585637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phenotypic, transcriptomic and metabolomic changes in Klebsiella pneumoniae after long term exposure to simulated microgravity. 长期暴露于模拟微重力环境后肺炎克雷伯菌的表型、转录组学和代谢组学变化。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-07-05 DOI: 10.1038/s41526-025-00489-6

Xia Wang, Zili Chai, Wenting Liu, Tianye Jia, Zilong Yang, Fengwei Zhang, Fuqiang Kang, Qiming Wang, Xianwei Ye, Hongguang Ren, Xiaodong Zai, Junjie Yue, Yuan Jin

{"title":"Phenotypic, transcriptomic and metabolomic changes in Klebsiella pneumoniae after long term exposure to simulated microgravity.","authors":"Xia Wang, Zili Chai, Wenting Liu, Tianye Jia, Zilong Yang, Fengwei Zhang, Fuqiang Kang, Qiming Wang, Xianwei Ye, Hongguang Ren, Xiaodong Zai, Junjie Yue, Yuan Jin","doi":"10.1038/s41526-025-00489-6","DOIUrl":"10.1038/s41526-025-00489-6","url":null,"abstract":"Klebsiella pneumoniae (K. pneumoniae) has been detected on space stations. Microgravity is a key environmental factor in spaceflight, however, research on the phenotypic, genetic, and metabolic changes K. pneumoniae undergoes due to long-term exposure to microgravity is still limited. K. pneumoniae was cultured under normal gravity (NG) and simulated microgravity (SMG) for 56 days, showing phenotypic changes like slower growth, larger and rounder cell morphology, and increased biofilm formation in SMG. RNA sequencing analysis revealed that the DEGs were associated primarily with metabolic and growth pathways, including those involved in biofilm formation. Metabolomic analysis revealed changes in the activity of the phenylalanine metabolic pathway, which was the most significantly enriched pathway, due to the interaction between the mhp gene cluster and related DEMs. Co-expression network analysis revealed intricate relationships between DEGs and DEMs, notably in arginine and proline metabolism. This study provides insights into K. pneumoniae's response mechanisms to microgravity.","PeriodicalId":54263,"journal":{"name":"npj Microgravity","volume":"11 1","pages":"35"},"PeriodicalIF":4.4,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12228701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144568072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the scientific and economic impacts of the experiments conducted onboard the International Space Station. 评估在国际空间站上进行的实验的科学和经济影响。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-07-03 DOI: 10.1038/s41526-025-00485-w

Max Wang, Ken Savin

引用次数: 0

High-risk private space missions have potential impact on government-sponsored programs. 高风险的私人太空任务对政府资助的项目有潜在的影响。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-07-03 DOI: 10.1038/s41526-025-00474-z

Hansjörg Schwertz, Dana Tulodziecki

引用次数: 0

In space fabrication of Janus base nano matrix for improved assembly and bioactivity. 在空间制备中改进Janus基纳米基质的组装和生物活性。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-07-02 DOI: 10.1038/s41526-025-00482-z

Anne Yau, Maxwell Landolina, Mari Anne Snow, Pinar Mesci, Brandon Williams, James B Hoying, Jana Stoudemire, Rayyanah Barnawi, Peggy Whitson, Rose Hernandez, Derek Duflo, Honglu Wu, Yupeng Chen

引用次数: 0

Impact of peripheral skin cooling on neuroendocrine leukocytic and hematological reactions during Hypergravity. 外周皮肤冷却对超重力时神经内分泌、白细胞和血液学反应的影响。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-07-02 DOI: 10.1038/s41526-025-00486-9

Michael Nordine, Niklas Kagelmann, Jan Kloka, Hanns-Christian Gunga, Viktor Heinz, Niklas Pilz, Oliver Opatz, Tomas L Bothe

{"title":"Impact of peripheral skin cooling on neuroendocrine leukocytic and hematological reactions during Hypergravity.","authors":"Michael Nordine, Niklas Kagelmann, Jan Kloka, Hanns-Christian Gunga, Viktor Heinz, Niklas Pilz, Oliver Opatz, Tomas L Bothe","doi":"10.1038/s41526-025-00486-9","DOIUrl":"10.1038/s41526-025-00486-9","url":null,"abstract":"Optimal neuroendocrine responses are essential during hypergravity (+Gz) exposure. Peripheral skin cooling (PSC) may enhance neuroendocrine function, potentially improving +Gz resiliency and influencing leukocyte and hematologic factors. This study investigated whether PSC augments the cumulative +Gz stress index (CGSI) and shifts it toward noradrenergic dependency. Eighteen men underwent a graded +Gz profile in a crossover design, with PSC applied using Arctic Sun cooling pads. Neuroendocrine and blood profiles were assessed pre- and post-+Gz. CGSI did not differ between groups, but serum osmolality increased only in PSC (p = 0.03). In PSC, CGSI correlated with norepinephrine (p < 0.01, r = 0.71) and other markers, suggesting enhanced norepinephrine responsiveness despite similar serum levels. This response may be cardio-protective for space missions and ICU patients. Additionally, baseline serum metanephrine emerged as a potential marker for +Gz resilience, with PSC showing potential leukocytic and hematologic involvement in CGSI.","PeriodicalId":54263,"journal":{"name":"npj Microgravity","volume":"11 1","pages":"30"},"PeriodicalIF":4.4,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preliminary considerations for accessible space missions for all. 对人人可进入空间飞行任务的初步考虑。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-07-02 DOI: 10.1038/s41526-025-00494-9

Irene Di Giulio, Ryan Anderton, Nicol Caplin, Peter Hodkinson, Mike J Miller-Smith, Marco V Narici, Ross D Pollock, Joern Rittweger, Thomas G Smith, Neil Tucker, Stephen D R Harridge

引用次数: 0

Soil conditioning for enhancing plant growth using biochar and hydrochar under microgravity. 微重力条件下生物炭和碳氢化合物促进植物生长的土壤调节。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-07-02 DOI: 10.1038/s41526-025-00491-y

Charles Wang Wai Ng, Yu Chen Wang

{"title":"Soil conditioning for enhancing plant growth using biochar and hydrochar under microgravity.","authors":"Charles Wang Wai Ng, Yu Chen Wang","doi":"10.1038/s41526-025-00491-y","DOIUrl":"10.1038/s41526-025-00491-y","url":null,"abstract":"Cultivating plants in outer space is crucial for bioregenerative life support systems in human space exploration. This study aims to investigate the effects of soil conditioning with biochar and hydrochar on the growth and production of Malabar Spinach in microgravity conditions. Peanut shell biochar and wood hydrochar were applied at a 3% dosage by mass. Two gravity conditions were considered, including 1 g and microgravity simulated by a Random Positioning Machine (RPM). After an 18-day plant growth period, microgravity reduced the fresh biomass accumulation of Malabar Spinach by up to 71%. This reduction was attributed to inhibited leaf and root growth, which decreased light interception and nutrient uptake. In microgravity, biochar was more effective than hydrochar in enhancing plant production, mitigating the growth inhibition caused by microgravity. In the presence of biochar, microgravity significantly enhanced the biosynthesis of chlorophyll a and carotenoids by up to 36%. Furthermore, biochar and hydrochar treatments in microgravity conditions significantly increased the nutrient contents, such as K and P, in Malabar Spinach leaves. These findings indicate that biochar and hydrochar are promising soil conditioners for enhancing plant development in low-gravity conditions.","PeriodicalId":54263,"journal":{"name":"npj Microgravity","volume":"11 1","pages":"31"},"PeriodicalIF":4.4,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12222869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Light is sufficient to compensate for random positioning machine-simulated microgravity in plant roots. 光足以补偿随机定位机模拟的植物根部微重力。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-07-01 DOI: 10.1038/s41526-025-00493-w

Rakesh David, Apriadi Situmorang, Nam Nghiep Tran, Thiri Maythwe, Volker Hessel, Philip B Brewer

{"title":"Light is sufficient to compensate for random positioning machine-simulated microgravity in plant roots.","authors":"Rakesh David, Apriadi Situmorang, Nam Nghiep Tran, Thiri Maythwe, Volker Hessel, Philip B Brewer","doi":"10.1038/s41526-025-00493-w","DOIUrl":"10.1038/s41526-025-00493-w","url":null,"abstract":"Growing food crops for space missions requires significant improvements in technical competence. Many issues remain, including ensuring that roots grow vertically in low gravity. Although plant roots grow towards gravity, they also perceive and bend away from light, allowing for light to substitute for gravity. To explore this issue, we designed a 3D-printed mini-phytotron with adjustable light-emitting diodes to use with a random positioning machine (RPM). Simulated microgravity in the RPM, together with darkness, caused Arabidopsis roots to lose vertical perception, resulting in significantly altered root morphology parameters consistent with gravity loss. This validated the method as an Earth-based analogue and allowed us to test the addition of light. White light as low as 10 μmol m-2 s-1 compensated for simulated microgravity in the RPM. Red light was less effective than white, and white light at 1 μmol m-2 s-1 was much less effective. A dwarf variant of Arabidopsis responded similarly to the wild type, and lettuce roots also responded to light. Food plants in space will require much higher levels than 10 μmol m-2 s-1 for photosynthesis, so there are good prospects that light in growth facilities in space will replace gravity for normal root growth, as long as roots can be exposed to some light. The RPM combined with the mini-phytotron was developed here as an inexpensive Earth-based analogue to analyse root growth behaviour to changing light levels under varying gravity conditions and will serve as a valuable experimental platform for further dissection of light responses in roots.","PeriodicalId":54263,"journal":{"name":"npj Microgravity","volume":"11 1","pages":"28"},"PeriodicalIF":4.4,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12216757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and flight-testing of modular autonomous cultivation systems for biological plastics upcycling aboard the ISS. 国际空间站生物塑料升级回收模块化自主培养系统的开发和飞行测试。

IF 4.4 1区物理与天体物理

npj Microgravity Pub Date : 2025-06-25 DOI: 10.1038/s41526-025-00463-2

Xin Liu, Pat Pataranutaporn, Benjamin Fram, Allison Z Werner, Sunanda Sharma, Nicholas P Gauthier, Erika Erickson, Patrick Chwalek, Kelsey J Ramirez, Morgan A Ingraham, Natasha P Murphy, Krista A Ryon, Braden T Tierney, Gregg T Beckham, Christopher E Mason, Ariel Ekblaw

{"title":"Development and flight-testing of modular autonomous cultivation systems for biological plastics upcycling aboard the ISS.","authors":"Xin Liu, Pat Pataranutaporn, Benjamin Fram, Allison Z Werner, Sunanda Sharma, Nicholas P Gauthier, Erika Erickson, Patrick Chwalek, Kelsey J Ramirez, Morgan A Ingraham, Natasha P Murphy, Krista A Ryon, Braden T Tierney, Gregg T Beckham, Christopher E Mason, Ariel Ekblaw","doi":"10.1038/s41526-025-00463-2","DOIUrl":"10.1038/s41526-025-00463-2","url":null,"abstract":"Cultivation of microorganisms in space has enormous potential to enable in-situ resource utilization (ISRU) Here, we develop an autonomous payload with fully programmable serial passaging and sample preservation, termed the Modular Open Biological Platform (MOBP), and flight-test the MOBP aboard the International Space Station (ISS) by conducting enzymatic and microbial plastics upcycling experiments. The MOBP is a compact, modular bioreactor system that allows for sustained microbial growth via automated media transfers, such as those for sample collection and storage for terrestrial analyses, and precise data monitoring from integrated sensors. The MOBP was flight-tested with two experiments designed to evaluate biological upcycling of the plastic poly(ethylene terephthalate) (PET). The bioproduct βKA can be polymerized into a nylon-6,6 analog with improved properties for use in the production of a variety of materials. We posit the MOBP will aid in democratizing the execution of synthetic biology in spaceflight towards enabling ISRU.","PeriodicalId":54263,"journal":{"name":"npj Microgravity","volume":"11 1","pages":"23"},"PeriodicalIF":4.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0