发布求助
文献互助 智能选刊 最新文献

Current Opinion in Physiology最新文献

筛选
英文 中文
Fostering interpersonal skills in the age of artificial intelligence 在人工智能时代培养人际交往能力
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.cophys.2026.100917
Chirag M Vaswani , Sandra Pereira , Helen Miliotis , Nohjin Kee , Michelle B French
{"title":"Fostering interpersonal skills in the age of artificial intelligence","authors":"Chirag M Vaswani ,&nbsp;Sandra Pereira ,&nbsp;Helen Miliotis ,&nbsp;Nohjin Kee ,&nbsp;Michelle B French","doi":"10.1016/j.cophys.2026.100917","DOIUrl":"10.1016/j.cophys.2026.100917","url":null,"abstract":"<div><div>As new digital technologies, including artificial intelligence (AI), reshape education, the interpersonal dimensions of learning, how students communicate, collaborate, empathize, and reason ethically, remain central to meaningful human interaction in the classroom. We examine how physiology educators can respond to a shifting landscape shaped by the emergence of generative AI and the disruptions of the pandemic. Drawing on current research, institutional responses, and practical classroom strategies, we highlight how human-centered pedagogy is being reimagined to foster interpersonal growth. From peer-led case studies and flipped labs to escape rooms and structured reflections, we showcase how educators are creating space for empathy, decision-making, and teamwork. Rather than sidestepping AI, we explore how it can be leveraged to enhance these interpersonal skills. The result is a practical framework for designing learning environments that prepare our graduates for an AI-shaped future while deepening their human connections.</div></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100917"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147420990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Engaging students in physiology beyond the lecture 让学生在课外学习生理学
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2026-02-05 DOI: 10.1016/j.cophys.2026.100908
Barbara E Goodman
{"title":"Engaging students in physiology beyond the lecture","authors":"Barbara E Goodman","doi":"10.1016/j.cophys.2026.100908","DOIUrl":"10.1016/j.cophys.2026.100908","url":null,"abstract":"<div><div>This review has been designed to update readers on experiential/active learning ideas for teaching physiology under the theme of ‘Teaching and Learning in Physiology’. We will begin with a short history of active learning in physiology teaching that highlights adding active learning activities into lecture-based courses; however, most of this review will provide resources for physiology educators to design and implement innovative active learning strategies with their students outside of didactic lectures. Evidence for various approaches of working in teams, incorporating theatre, gaming, social media, and new technologies, is included for modifying physiology teaching globally and with different types of students. The variety of options has been shown to enhance student learning and make difficult concepts relevant and fun. Advances in Physiology Education (<span><span>https://journals.physiology.org/journal/advances</span><svg><path></path></svg></span>) has published a number of these resources. The author of this paper is completing a six-year term as Editor-in-Chief of Advances.</div></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100908"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147420993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unraveling the role of the pulmonary renin–angiotensin system in inflammatory lung injury and hypertension 揭示肺肾素-血管紧张素系统在炎性肺损伤和高血压中的作用
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2025-11-28 DOI: 10.1016/j.cophys.2025.100876
Chuanming Xu , Ying Zhu , Mengzhi Zhu
{"title":"Unraveling the role of the pulmonary renin–angiotensin system in inflammatory lung injury and hypertension","authors":"Chuanming Xu ,&nbsp;Ying Zhu ,&nbsp;Mengzhi Zhu","doi":"10.1016/j.cophys.2025.100876","DOIUrl":"10.1016/j.cophys.2025.100876","url":null,"abstract":"<div><div>Inflammatory lung injury involves pulmonary renin–angiotensin system (RAS) imbalance, manifested as excessive activation of the ACE/AngII/AT<sub>1</sub>R axis and reduced activity of the ACE2/Ang/1–7/MasR axis. This imbalance may serve as an important bridge connecting hypertension and inflammatory lung injury. Multiple pathological conditions, including respiratory virus infections, acute lung injury, acute respiratory distress syndrome, chronic obstructive pulmonary disease, and idiopathic pulmonary fibrosis, activate the ACE/AngII/AT<sub>1</sub>R axis and inhibit the ACE2/Ang/1–7/MasR axis in the lungs. Restoring dual-axis balance reduces blood pressure and mitigates inflammatory lung injury, making the pulmonary RAS a promising therapeutic target. This review outlines the existing evidence regarding the role of pulmonary RAS in the context of inflammatory lung injury and hypertension, emphasizing mechanistic insights and potential therapeutic implications.</div></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100876"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145739257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial overview: Extracellular vesicles: from biological insight to translational promise 编辑概述：细胞外囊泡：从生物学的洞察力到翻译的前景
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2025-12-12 DOI: 10.1016/j.cophys.2025.100887
Susmita Sahoo , Benedetta Bussolati
{"title":"Editorial overview: Extracellular vesicles: from biological insight to translational promise","authors":"Susmita Sahoo ,&nbsp;Benedetta Bussolati","doi":"10.1016/j.cophys.2025.100887","DOIUrl":"10.1016/j.cophys.2025.100887","url":null,"abstract":"","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100887"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145926319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inclusive education in the biosciences: what do we mean and how can we achieve it? 生物科学的全纳教育：我们的意思是什么？我们如何实现它？
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2026-02-04 DOI: 10.1016/j.cophys.2026.100906
Katharine Hubbard
{"title":"Inclusive education in the biosciences: what do we mean and how can we achieve it?","authors":"Katharine Hubbard","doi":"10.1016/j.cophys.2026.100906","DOIUrl":"10.1016/j.cophys.2026.100906","url":null,"abstract":"<div><div>Inclusive education is essential to dismantling structural biases and creating equitable academic environments. Genuine inclusion must go beyond meeting individual needs, but empower all to be ethical and responsible members of a diverse Global community. This article focuses on inclusive education within the biosciences. It explores issues such as inequitable student outcomes, access to practical work, scientific racism, ableism and global exploitation. Bioscience education research demonstrates that inclusive pedagogies improve student experience and student outcomes. I present an inclusive education framework to guide the transformation of structures, curriculum, assessment, community and student success. I call on bioscience educators to reflect and take action to ensure all bioscientists can thrive and contribute ethically to a diverse global society.</div></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100906"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147420997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Crosstalk between the renin–angiotensin system and the dopaminergic system in inflammation 炎症中肾素-血管紧张素系统和多巴胺能系统之间的串扰
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2026-01-23 DOI: 10.1016/j.cophys.2026.100905
Ornella Conte, Ezequiel Bruna-Haupt, Felicitas de Tezanos Pinto, Mariela M Gironacci
{"title":"Crosstalk between the renin–angiotensin system and the dopaminergic system in inflammation","authors":"Ornella Conte,&nbsp;Ezequiel Bruna-Haupt,&nbsp;Felicitas de Tezanos Pinto,&nbsp;Mariela M Gironacci","doi":"10.1016/j.cophys.2026.100905","DOIUrl":"10.1016/j.cophys.2026.100905","url":null,"abstract":"<div><div>Inflammation is a common feature of many chronic disorders, including cardiovascular, renal, metabolic, and neurodegenerative diseases. The renin–angiotensin system (RAS) has emerged as a major regulator of inflammatory processes. Its classical pressor axis promotes pro-inflammatory and oxidative responses, thereby contributing to the progression of various inflammatory diseases, while the counter-regulatory axis exerts anti-inflammatory and protective effects. Dopamine (DA), traditionally recognized as a neurotransmitter involved in motor activity, cognition, and reward, also functions as an immunomodulatory agent acting in both central and peripheral systems. Low-affinity DA receptors mediate anti-inflammatory actions, whereas high-affinity receptors enhance immune responses. This review outlines current evidence for RAS–DA crosstalk in inflammation.</div></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100905"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147421098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gamification for assessment in medical education: exploring current evidence and future directions from broader educational contexts 医学教育评估的游戏化：从更广泛的教育背景探索当前的证据和未来的方向
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.cophys.2026.100907
Krishna Mohan Surapaneni
{"title":"Gamification for assessment in medical education: exploring current evidence and future directions from broader educational contexts","authors":"Krishna Mohan Surapaneni","doi":"10.1016/j.cophys.2026.100907","DOIUrl":"10.1016/j.cophys.2026.100907","url":null,"abstract":"<div><div>Assessment is central to medical education, shaping both learner behavior and professional identity. Traditional examinations and structured evaluations provide rigor, but they are often criticized for being stressful and narrowly focused. Gamification, the integration of game design elements such as points, badges, and leaderboards, has emerged as an innovative approach to reshape assessment. While widely applied to teaching and simulation, its role in assessment is only beginning to be explored. This review synthesizes the available evidence on gamification in assessment within medical education and, given the limited number of medical-specific studies, incorporates findings from broader educational contexts. It evaluates how assessment approaches tested in these wider settings may translate to, and inform, assessment design in medical education. Gamification is best supported as a formative assessment that promotes practice, motivation, and feedback-rich learning, and effective implementation requires thoughtful alignment with educational objectives rather than superficial use of game elements.</div></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100907"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147420995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unlocking therapies for neurodegeneration: targeting mitochondrial dysfunction and oxidative stress in Alzheimer’s disease 解锁神经退行性疾病的治疗：针对阿尔茨海默病的线粒体功能障碍和氧化应激
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2025-11-20 DOI: 10.1016/j.cophys.2025.100874
Jia Hui Wong, Kei Onn Lai, Anna M Barron
{"title":"Unlocking therapies for neurodegeneration: targeting mitochondrial dysfunction and oxidative stress in Alzheimer’s disease","authors":"Jia Hui Wong,&nbsp;Kei Onn Lai,&nbsp;Anna M Barron","doi":"10.1016/j.cophys.2025.100874","DOIUrl":"10.1016/j.cophys.2025.100874","url":null,"abstract":"<div><div>Alzheimer’s disease (AD) arises not only from protein aggregates but also from a breakdown in cellular energy and redox balance. Early mitochondrial defects cause excess reactive oxygen species, undermining neuronal synapses, while microglia shift into a glycolysis-driven, proinflammatory state that hinders amyloid clearance. Cutting-edge imaging and single-cell profiling now reveal these metabolic derangements before hallmark plaques emerge. This review synthesizes recent insights into mitochondrial oxidative stress, microglial metabolic reprogramming, and neurovascular redox imbalance, highlighting evidence that restoring mitochondrial function improves disease outcomes. We also examine how artificial intelligence accelerates the identification of oxidative-stress biomarkers and mitochondria-targeted therapeutics through integrative analyses of omics, imaging, and clinical datasets. Together, these mechanistic and computational advances point toward mitochondria-centered, data-driven strategies for precision therapy and early intervention in AD.</div></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100874"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145705539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circadian physiology changes with aging: age is just a number, but circadian physiology keeps time 生理昼夜随着年龄的增长而变化：年龄只是一个数字，但生理昼夜保持着时间
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2025-11-21 DOI: 10.1016/j.cophys.2025.100875
Natalie J Bohmke, Karyn A Esser
{"title":"Circadian physiology changes with aging: age is just a number, but circadian physiology keeps time","authors":"Natalie J Bohmke,&nbsp;Karyn A Esser","doi":"10.1016/j.cophys.2025.100875","DOIUrl":"10.1016/j.cophys.2025.100875","url":null,"abstract":"<div><div>Circadian rhythms are inherent cycles of physiology and behavior that occur over approximately 24 h and are modulated by the cell-autonomous molecular clock. The molecular clocks throughout the body are aligned by the suprachiasmatic nucleus to contribute to robust daily variation of physiology, including core temperature, blood pressure, and heart rate. Alterations to the alignment of circadian clocks and changes to circadian rhythms of behavior and physiological processes are contributors to parameters that impact health and disease. In this review, we summarize what is known about changes to circadian rhythms of human behavior and physiology during older adulthood and the opportunities for future investigation of circadian physiology in older adults.</div></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100875"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145705827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel aspects of the renin-angiotensin-aldosterone system in septic shock 脓毒性休克中肾素-血管紧张素-醛固酮系统的新进展
IF 1.9
Current Opinion in Physiology Pub Date : 2026-03-01 Epub Date: 2025-12-24 DOI: 10.1016/j.cophys.2025.100894
Christopher L Schaich , Ashish K Khanna , Mark C Chappell
{"title":"Novel aspects of the renin-angiotensin-aldosterone system in septic shock","authors":"Christopher L Schaich ,&nbsp;Ashish K Khanna ,&nbsp;Mark C Chappell","doi":"10.1016/j.cophys.2025.100894","DOIUrl":"10.1016/j.cophys.2025.100894","url":null,"abstract":"<div><div>Sepsis and septic shock are associated with high mortality rates and constitute the primary cause of death in intensive care units worldwide. Activation of the circulating renin-angiotensin-aldosterone system (RAAS) is an early event, and elements of the RAAS, including renin, Angiotensinogen, and ACE2, may be predictive of worse outcomes and higher mortality that reflect a failure to increase the circulating levels of the vasopressor Ang II. Emerging evidence suggests that dipeptidyl peptidase III (DPP3) is involved in the metabolism of Ang II, and higher DPP3 in septic shock may contribute to lower Ang II tone. The current review considers the role of a dysfunctional RAAS to maintain blood pressure and adequate tissue perfusion in septic shock.</div></div>","PeriodicalId":52156,"journal":{"name":"Current Opinion in Physiology","volume":"47 ","pages":"Article 100894"},"PeriodicalIF":1.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145977636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信
小红书