Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)最新文献

{"title":"Progress in the Synthesis of Evidence in Glaucoma: What We Know and the Gaps that Remain.","authors":"Mapa Prabhath Piyasena, Gianni Virgili, Augusto Azuara-Blanco","doi":"10.1007/s44402-026-00218-w","DOIUrl":"10.1007/s44402-026-00218-w","url":null,"abstract":"<p><strong>Purpose: </strong>Glaucoma is one of the leading causes of blindness worldwide, necessitating evidence-informed interventions and strategies to improve the quality of life of affected individuals. In this review, we examined progress in evidence over the past decade and discussed its implications and the ways forward for delivery of glaucoma care globally, embedded within a rapid evidence and gap-mapping exercise of systematic reviews and/or meta-analyses published between 2015 and 2025.</p><p><strong>Methods: </strong>Using a predefined conceptual framework, ten domains were identified as relevant to evidence synthesis in glaucoma care. Within each domain, we assessed areas of strength and identified remaining evidence gaps. Findings were synthesised narratively and recommendations provided to inform future research priorities and advancement in glaucoma care.</p><p><strong>Recent findings: </strong>Across the systematic reviews published over the past decade, the majority focused on risk factors (15.6%), genetic factors (12.4%) and the effectiveness of various treatment modalities (44.4%). In the absence of a coordinated global approach, substantial duplication of effort across review groups was observed. In addition, several critical gaps remain in the evidence base, particularly regarding the cost-effectiveness of the interventions, improving equitable access to care and the availability of context-specific evidence for low- and middle-income countries. Improved rigour in the evidence from primary studies should be a key priority for future research. A substantial gap exists in the glaucoma care evidence base that limits its utility for informing clinical guidelines and policy development. Systematic reviewers should have a comprehensive understanding of the existing evidence landscape in glaucoma care prior to conceptualising and designing review projects. Strengthening the methodological quality of both systematic reviews and the underlying primary studies is essential to support the development of robust clinical guidelines and effective global policies in glaucoma care.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":"1296-1304"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evolving Landscape of Vision Rehabilitation: Current Status and Future Directions.","authors":"Amritha Stalin, Andrew Miller, Hilde van der Aa, Simona Turco, Tammy Labreche, Stefania Fortini, Carlotta Lalla, Filippo Amore, Michael Crossland, Gianni Virgili, Benjamin Thompson, Ruth van Nispen","doi":"10.1007/s44402-026-00088-2","DOIUrl":"10.1007/s44402-026-00088-2","url":null,"abstract":"<p><p>Vision impairment is increasingly recognised as a complex condition shaped not only by ocular pathology but also by cognitive, psychological, social and environmental factors that influence participation and quality of life. In line with the United Nations Convention on the Rights of Persons with Disabilities and the International Classification of Functioning, Disability and Health, contemporary vision rehabilitation frameworks adopt a biopsychosocial perspective that extends beyond treatment of the eye condition alone toward holistic support to improve the lives of individuals with vision loss. An overview of the effectiveness and future directions of multidisciplinary vision rehabilitation in clinical practice is presented, and a summary of the findings concerning the international standards of vision rehabilitation, focusing on adults. Furthermore, some examples of achievements in emerging fields are presented, such as neuroplasticity and visual system recovery, technological interventions and psychosocial support, including their future directions. Multidisciplinary models are widely supported but remain difficult to implement because of limited resources, workforce constraints and differences in culture and health policy. Overcoming these barriers is critical to expanding and strengthening multidisciplinary vision rehabilitation. The evidence highlights the need for implementation-focused research, closer collaboration across disciplines and core outcome measures that capture participation, mental health and quality of life, not just impairment. The overview also points to the importance of structured models that integrate neurorehabilitation (artificial intelligence-based) technology and mental healthcare while adapting to regional and cultural contexts. Embedding multidisciplinary vision rehabilitation within health systems is both a clinical necessity and a prerequisite for advancing global commitments to inclusion and equity for people with vision impairment. As population ageing and global demographic change are expected to increase the absolute numbers of adults with vision loss, strengthening collaboration between research, clinical practice and service delivery will be essential to further improve the quality of life of individuals with vision loss.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":"1397-1406"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147826301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global and Regional Risk Factors for Vision Impairment in 2020 and Multi-decadal Trends 1990-2020: A Meta-Analysis and Visual Display Based on Prevalence Data From the Global Burden of Disease study and Vision Loss Expert Group.","authors":"Michele Bottone, Jost Jonas, Jaimie Steinmetz, Tasanee Braithwaite, Robert Casson, Joshua Ehrlich, Hugh R Taylor, David Friedman, Nathan Congdon, John Kempen, Janet Leasher, Ningli Wang, Rohit Khanna, Tunde Peto, Joao M Furtado, Tien Y Wong, Mary E Hartnett, Maria V Cicinelli, Nina Tahhan, Van C Lansingh, Sophia Y Wang, Ian Tapply, Paul Briant, Theo Vos, Serge Resnikoff, Seth R Flaxman, Rupert R A Bourne","doi":"10.1007/s44402-026-00208-y","DOIUrl":"10.1007/s44402-026-00208-y","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate global and regional risk factors for blindness and vision impairment pertaining to all geographical locations between 1990 and 2020.</p><p><strong>Methods: </strong>(1) Twenty-four covariates were selected with a potential link to vision impairment from the Global Burden of Disease Study (GBD) Covariates database as predictive factors. (2) From these, the linear association was investigated, with crude and age-standardised prevalence estimates of blindness and distance and near vision impairment in 2020 by using data for the whole population, sex and 5-year age groups, and by stratifying severity through mild, moderate, severe and total impairment. (3) Analysis investigated whether percentage rates of change in risk factors were associated with rates of change in prevalence in 1990-2020.</p><p><strong>Results: </strong>For adults (50+ years), for crude and age-standardised vision loss prevalence estimates for the year 2020, a significant negative association of smoking prevalence was found initially for all persons and for each sex, which appears to be due to ecological confounding and became a positive association using more granular regional and age group data. Maternal care and immunisation, sanitation proportion, Health Access and Quality Index and Socio-demographic Index were other significant age-standardised negative associations. Ophthalmologists/million population had a weak but significant protective effect, and positive associations were found for pollution (outdoor and indoor), stronger for greater vision impairment severities. Years in education per capita were weakly, negatively associated with vision loss prevalence, yet zero education proportion had a stronger but positive association for both sexes.</p><p><strong>Conclusions: </strong>This study confirmed associations at population level globally, which appear to be stable over decades. In addition, the study quantified the contribution of epidemiologically-based risk factors to vision loss at a GBD super-regional level, which is novel. This opens useful avenues for targeted intervention by policymakers. For example, reduction in sex inequity in blindness rates over 30 years has been positively associated with reducing overall prevalence of blindness.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":"1262-1271"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary Perspectives and Future Directions in Ophthalmic and Physiological Optics.","authors":"Joanne M Wood, Shahina Pardhan","doi":"10.1007/s44402-026-00201-5","DOIUrl":"10.1007/s44402-026-00201-5","url":null,"abstract":"","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":"1259-1261"},"PeriodicalIF":2.4,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reading Arabic Under Simulated Low Vision: Orthographic Complexity Shapes the Effect of Contrast Polarity.","authors":"Balsam Alabdulkader, Alhanouf Alghannam, Ali Almustanyir, Essam Almutleb, Mosaad Alhassan","doi":"10.1007/s44402-026-00225-x","DOIUrl":"https://doi.org/10.1007/s44402-026-00225-x","url":null,"abstract":"<p><strong>Purpose: </strong>Reading is a critical visual task that depends on the resolution of fine character features, and how these features are affected by display variables under degraded viewing conditions remains an important question in clinical psychophysics. While contrast polarity effects on reading have been documented in Latin scripts, evidence from non-Latin orthographies is limited. This study investigated the effect of contrast polarity on Arabic reading performance under simulated visual impairment.</p><p><strong>Methods: </strong>Reading acuity (RA), maximum reading speed (MRS) and critical print size (CPS) were assessed in 47 normally sighted adults using the Balsam Alabdulkader-Leat (BAL) reading chart. Testing was conducted under baseline and simulated visual impairment using a Bangerter filter, with both black-on-white and white-on-black charts.</p><p><strong>Results: </strong>The simulation significantly degraded all reading measures (MRS, p = 0.001; RA, p < 0.0001; CPS, p < 0.0001). A significant simulation × polarity interaction was found for RA (p < 0.0001), with black-on-white charts producing better visual acuity at baseline and white-on-black producing better visual acuity under simulated impairment. Chart polarity did not affect MRS (p = 0.38) or CPS (p = 0.82) significantly.</p><p><strong>Conclusion: </strong>Arabic relies on small, high-spatial-frequency features such as dots for letter discrimination, which appear to modulate how contrast polarity interacts with optical degradation at threshold. These findings provide preliminary evidence that may guide future studies of reading performance in Arabic-speaking patients with visual impairment.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149248372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thank You to Our 2026 Reviewers.","authors":"Mark Rosenfield","doi":"10.1007/s44402-026-00214-0","DOIUrl":"https://doi.org/10.1007/s44402-026-00214-0","url":null,"abstract":"","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149248376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Axial Length Response Predicts Long-Term Myopia Control in Children Undergoing Orthokeratology.","authors":"Jacinto Santodomingo-Rubido, César Villa-Collar","doi":"10.1007/s44402-026-00224-y","DOIUrl":"https://doi.org/10.1007/s44402-026-00224-y","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate whether early axial length (AL) change after 6 months of orthokeratology (OK) wear serves as a clinically meaningful biomarker for predicting long-term myopia control after 2 years.</p><p><strong>Methods: </strong>This retrospective analysis included 101 children from a multicentre OK cohort who completed 24 months of follow‑up, with AL measured at baseline and at 6, 12, 18 and 24 months. Early AL shortening was defined as a ≥0.01 mm reduction after 6 months. Longitudinal AL change was assessed using linear mixed‑effects models. To evaluate predictive utility, separate logistic regression models were fitted using the 6-month AL change (ΔAL₆_m) as a continuous predictor for two predefined AL outcome categories: favourable AL response (ΔAL₂₄_m ≤ 0.30 mm) and poor AL response (>0.59 mm). Receiver operating characteristic (ROC)‑derived probability thresholds were obtained using Youden's J statistic. External validation was performed in an independent OK cohort of 69 Japanese children (138 eyes).</p><p><strong>Results: </strong>Fourteen children (13.9%) showed early AL shortening. Mixed‑effects modelling showed a significant time × shortening interaction (p < 0.001), with shorteners elongating by ∼0.006 mm/month versus ∼0.019 mm/month in non‑shorteners, yielding ∼0.33 mm less AL growth at 24 months. ΔAL₆_m strongly predicted a favourable AL response (area under the curve (AUC) = 0.90, p < 0.001), with an optimal threshold p*=0.33 corresponding to ΔAL₆_m ≈ +0.07 mm. ΔAL₆_m also predicted a poor AL response (AUC = 0.86, p < 0.001), with p*=0.11 (ΔAL₆_m ≈ +0.09 mm). External validation confirmed high AUCs (0.92 and 0.86) but revealed imperfect calibration, particularly for poor AL response.</p><p><strong>Conclusions: </strong>Early AL change after 6 months of OK wear is a useful biomarker for risk‑stratifying long‑term myopia control response. Children with ΔAL₆_m ≤ 0.07 mm were much more likely to achieve a favourable AL response, whereas those with ΔAL₆_m ≥ 0.09 mm had an elevated risk of poor AL response.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149248342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Corneal Epithelium to Endothelium: Long-Term Corneal Changes in Myopic Children Wearing Daily Disposable Hydrogel Soft Contact Lenses.","authors":"Hiu Yan Lam, Raquel Gil-Cazorla, Susie Jones, Nicola S Logan","doi":"10.1007/s44402-026-00211-3","DOIUrl":"https://doi.org/10.1007/s44402-026-00211-3","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to investigate the long-term impact of soft contact lens (SCL) wear on the cornea in children.</p><p><strong>Methods: </strong>Twenty-one participants who had worn daily disposable hydrogel SCLs for over 10 years (≥10 h/day, 6 days/week) since ages 8-12 years were recruited, together with age-matched controls without contact lens wear. Corneal epithelial (CET) and stromal thickness (CST) were measured using anterior segment optical coherence tomography in central (2 mm), mid-peripheral (2-5 mm) and peripheral (5-6 mm) annular regions. Corneal endothelium was imaged with a non-contact specular microscope to calculate corneal endothelial cell density (ECD), coefficients of variation of cell size (polymegethism, CV,%) and percentage of hexagonal cells (pleomorphism, HEX,%) in the central and six peripheral regions.</p><p><strong>Results: </strong>Participants' mean age was 21.3 ± 1.2 years in the control group (12 females) and 21.6 ± 1.5 years in the SCL group (10 females). Mean central 2-mm CET and CST were similar between groups (CET: Control vs SCL: 52.4 ± 3.4 vs 52.2 ± 2.5 μm, CST: 478.3 ± 30.8 vs 487.6 ± 23.4, both p > 0.20), with no significant differences in peripheral regions (p > 0.10). Neither central ECD (3064 ± 249 vs 3076 ± 203 cells/mm²), HEX (67.3 ± 6.8 vs 65.9 ± 7.4%) nor CV (28.0 ± 3.8 vs 29.8 ± 3.8%) differed significantly between groups (p > 0.10). The SCL group showed significantly higher CV in the superior and superonasal regions only (p = 0.01), while peripheral ECD and HEX were similar between groups (all p > 0.10).</p><p><strong>Conclusion: </strong>Long-term wear of daily disposable hydrogel SCLs in children did not alter CET and CST significantly over a minimum 10-year period. Corneal endothelial integrity and pleomorphism were maintained, with higher polymegethism observed only in two peripheral regions. These findings support daily disposable hydrogel SCLs as a safe and suitable choice for children over a typical myopia control treatment period.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149241046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of Refractive Error in Ghana: A Systematic Review and Meta-Analysis.","authors":"Samuel Kyei, Randy Asiamah, Pious Tawiah Amoako, Hornametor Afake","doi":"10.1007/s44402-026-00202-4","DOIUrl":"https://doi.org/10.1007/s44402-026-00202-4","url":null,"abstract":"<p><strong>Purpose: </strong>To synthesise the population-based prevalence of myopia, hyperopia and astigmatism in Ghana and evaluate the methodological drivers of heterogeneity within the existing epidemiological literature.</p><p><strong>Recent findings: </strong>A systematic review and meta-analysis of nine eligible population-based cross-sectional studies (n = 7153 participants, age range 5-70 years) was conducted. Due to substantial inter-study heterogeneity, pooled estimates should be interpreted as weighted averages rather than definitive national prevalences. The pooled prevalence was approximately 3.1% (95% CI: 1.9% to 5.0%) for myopia, 2.2% (95% CI: 1.1% to 4.4%) for hyperopia and 1.7% (95% CI: 0.7% to 3.9%) for astigmatism. Prediction intervals were wide, reflecting extreme between-study variance. Subgroup analyses revealed that myopia prevalence was significantly higher in urban (3.1%) and mixed settings (4.7%) compared with rural areas (0.8%; 95% CI: 0.4% to 1.6%). Furthermore, studies omitting cycloplegia severely underestimated hyperopia prevalence (1.3%) compared to the single cohort utilising cycloplegic refraction (4.6%). Continuous meta-regression indicated a positive correlation between hyperopia and advancing age, while apparent temporal declines in hyperopia and astigmatism may reflect methodological shifts rather than true epidemiological trends. The findings suggest higher myopia prevalence in urban and mixed settings and indicate that cycloplegic use may influence reported hyperopia prevalence estimates. Future epidemiological studies would benefit from standardised cycloplegic protocols and harmonised refractive error definitions to improve comparability of prevalence estimates.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffractive Soft Contact Lenses for Modifying Ocular Longitudinal Chromatic Aberration.","authors":"Len Zheleznyak, Chang Liu, Lisen Xu","doi":"10.1007/s44402-026-00212-2","DOIUrl":"https://doi.org/10.1007/s44402-026-00212-2","url":null,"abstract":"<p><strong>Purpose: </strong>Childhood myopia prevalence is increasing rapidly worldwide, underscoring the need for effective strategies to slow its progression. Longitudinal chromatic aberration (LCA) has been identified as an optical cue for the sign of defocus that may guide childhood eye growth and emmetropisation. Reversing the sign of ocular LCA has been proposed as a myopia control strategy, yet no wearable devices have demonstrated this capability. Here, diffractive soft contact lenses fabricated using laser-induced refractive index change (LIRIC) are introduced to modify ocular LCA.</p><p><strong>Methods: </strong>Contact lenses were made with four diffractive powers (1.5, 2.0, 3.0 and 6.0 D) using LIRIC, a femtosecond laser writing technique that modifies the internal refractive index of a soft contact lens without altering external geometry. Lens LCA was characterised using a custom multi-wavelength Badal optical bench with narrow bandpass filters (470, 532, 550, 630 and 700 nm). LCA was defined as the linear slope of relative optical power versus wavelength (D/μm). Theoretical predictions were derived from a first-order thin lens model using the negative Abbe number of diffractive wavefronts (-3.45).</p><p><strong>Results: </strong>Measured LCA values of the lenses were 2.77, 3.78, 5.31 and 11.37 D/μm for LIRIC lenses of 1.5, 2.0, 3.0 and 6.0 D of diffractive power, respectively, in close agreement with theoretical predictions (2.73, 3.64, 5.45 and 10.91 D/μm). Theoretical modelling of a diffraction-limited eye with average human LCA predicted that the 1.5 and 2.0 D diffractive designs partially compensated the eye's native LCA, the 3.0 D design minimised it and the 6.0 D design reversed its sign.</p><p><strong>Conclusions: </strong>This study presents the first demonstration of a soft contact lens capable of manipulating ocular LCA, including sign reversal. LIRIC diffractive contact lenses offer a practical platform for tuning the eye's chromatic defocus cues and warrant further investigation as a novel myopia control strategy.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}