Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)最新文献

{"title":"Diverse Segments Defocus Optimization spectacle lenses induce rapid changes in axial length and regional changes in choroidal thickness in children with myopia.","authors":"Mengfan Yang, Yumiao Chen, Yefeng Liu, Jianhua Yang, Sha Lv, Shichun Liu, Yaoxi Dong, Qiao Yang, Keyi Li, Shengfang Song, Hua Li","doi":"10.1111/opo.13532","DOIUrl":"https://doi.org/10.1111/opo.13532","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate rapid changes in axial length (AL) and regional changes in choroidal thickness (ChT) and the choroidal vessel index (CVI) in myopic children with myopia caused by optical defocus.</p><p><strong>Methods: </strong>Sixty-two eyes of 31 children wearing Diverse Segments Defocus Optimization (DSDO) spectacle lenses and 58 eyes of 29 children wearing single-vision spectacle lenses (SVL) were included. All participants were fully corrected and evaluated before and immediately after 30 min of reading. ChT and CVI were measured using swept-source optical coherence tomography in different regions, including the central, inner and outer ring areas and the superior, inferior, nasal and temporal regions. AL was also measured.</p><p><strong>Results: </strong>At baseline, ChT was significantly lower in the nasal quadrant than in other quadrants (all p < 0.001) and the CVI was significantly higher in the nasal quadrant than in the superior and temporal quadrants (all p < 0.01). After 30 min of reading, AL was significantly reduced in the DSDO group and increased in the SVL group. In the DSDO group, the ChT increased significantly in all areas, with the greatest increase observed in the inner ring area. In the SVL group, the ChT decreased in all areas, with the smallest decrease occurring in the inner ring area. CVI did not change significantly after reading in either group.</p><p><strong>Conclusions: </strong>In the early stage of lens wear, SVL induced a rapid increase in AL and decreased ChT in different areas, while DSDO induced rapid AL shortening and increased ChT in varying regions. ChT differed more in the inner than in the outer ring regions, while the superior region showed the most significant change in ChT. These findings provide new perspectives for the optimal design of optical defocus lenses.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraocular pressure and ocular perfusion pressure responses during low-intensity endurance exercise in primary-open angle glaucoma patients versus age- and sex-matched controls: Influence of walking pace and external load.","authors":"María Dolores Morenas-Aguilar, Cristina González Hernández, Sara Chacón-Ventura, Santiago Ortiz-Perez, Juan Francisco Ramos-López, Amador García-Ramos, Jesús Vera","doi":"10.1111/opo.13531","DOIUrl":"https://doi.org/10.1111/opo.13531","url":null,"abstract":"<p><p>This study compared the effects of low-intensity endurance exercise at two different walking paces with/without external loads on intraocular pressure (IOP) and ocular perfusion pressure (OPP) in primary open-angle glaucoma patients (POAG) and matched controls. Twenty-one POAG patients and 17 healthy individuals performed four 400-m walking protocols (slow/fast × with/without loads). IOP was measured before exercise, during the walking test and after 1 and 5 min of recovery. OPP was assessed before exercise and after 1 and 5 min of recovery. IOP was stable in POAG patients during the execution of low-intensity endurance exercise (p = 0.14) regardless of the walking pace and the use of external loads (both p > 0.69). However, controls showed a moderate IOP rise during the walking test (p < 0.001), with this effect being heightened when using external loads (p < 0.001). Both groups experienced a transient OPP rise after exercise (p < 0.001) and this increase was greater in the fast- than the slow-paced condition (p = 0.049). POAG patients showed stable IOP while walking at slow and fast speeds, while OPP increased after walking, particularly at a fast pace. These findings suggest that low-intensity endurance exercise is a safe strategy to improve fitness levels in POAG patients.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accommodative behaviour and retinal defocus of children during prolonged viewing of electronic devices while wearing dual-focus myopia control soft contact lenses.","authors":"Neeraj K Singh, Pete Kollbaum","doi":"10.1111/opo.13533","DOIUrl":"https://doi.org/10.1111/opo.13533","url":null,"abstract":"<p><strong>Purpose: </strong>Chronic hyperopic defocus from inadequate accommodation during near tasks may be associated with axial eye growth. This study examined accommodative behaviour and retinal defocus in myopic and emmetropic children after 1 h of continuous electronic device use.</p><p><strong>Methods: </strong>Thirty-four children (17 per group, aged 7-17) participated, including myopes wearing dual-focus (DF) myopia control contact lenses (MiSight 1-day) and uncorrected emmetropes. In phase one, on-axis aberrometry data were collected at distances from 4.00 to 0.20 m, corresponding to target vergences from -0.25 to -5.00 D. In phase two, measurements were taken every 10 mins, as children watched a movie at 0.20 m for 60 min. Local refractive state measures were calculated from aberrometry measures and pooled within pupil areas corresponding to DF lens central and treatment zones. Retinal defocus was calculated by subtracting target vergence from the measured refractive state. Linear mixed-effects models analysed group, target vergence and time effects on defocus, adjusting for pupil diameter.</p><p><strong>Results: </strong>Myopes with DF lenses showed greater hyperopic defocus (+0.58 D, p = 0.001) than uncorrected emmetropes during on-axis viewing. Hyperopic defocus increased significantly over time in both groups with near viewing (p < 0.001). Myopic defocus induced by DF lenses was still present but decreased following 50 and 60 min of near viewing (p = 0.05 and p = 0.007, respectively).</p><p><strong>Conclusions: </strong>Periods of sustained near viewing of up to 1 h increased hyperopic defocus in both groups. However, DF contact lenses still introduced myopic defocus in myopic subjects throughout this time, supporting their potential to slow axial eye growth during periods of sustained near viewing. Further work will be helpful to understand how the sustained near viewing model and associated results of the current work relate to the real-world environment, which may include potential breaks and/or longer total near viewing durations.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144176473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Axial elongation as a marker to identify obvious myopic shift in non-myopic eyes of Chinese children.","authors":"Shang Liu, Xiangui He, Padmaja Sankaridurg, Jingjing Wang, Linlin Du, Bo Zhang, Xun Xu, Jun Chen","doi":"10.1111/opo.13530","DOIUrl":"https://doi.org/10.1111/opo.13530","url":null,"abstract":"<p><strong>Purpose: </strong>Rapid axial elongation in emmetropic eyes may indicate an increased risk of myopia onset. This study aimed to examine the range of axial elongation in non-myopic eyes, to distinguish between those with and without an obvious myopic shift and establish criteria to predict myopia onset within 1 year.</p><p><strong>Methods: </strong>A total of 1580 non-myopic participants aged 6-10 years with -0.50 D < baseline spherical equivalent (SE) < +2.00 D were included. Eyes with an annual absolute SE change >0.25 and ≤0.25 D were categorised as 'high myopia risk group' and 'low myopia risk group', respectively. Annual axial elongation was calculated and presented as percentiles. The receiver operating characteristic (ROC) curve was used to determine the effectiveness for differentiating between these two groups and for predicting 1-year myopia onset.</p><p><strong>Results: </strong>Of the 3797 eyes, 1415 (37.3%) were in the low myopia risk group. Depending on age, the median annual axial length (AL) change varied between 0.31 and 0.38 mm/year and 0.15-0.21 mm/year in the high and low myopia risk groups, respectively. Annual AL change was fairly stable across age for all percentiles in both groups, except for the 95th percentile in the high myopia risk group that demonstrated reduced progression with age. The area under the ROC curve (AUC) for axial elongation to differentiate between the two groups was 0.83, with a cut-off >0.20 mm/year being the preferred value to ensure higher sensitivity. Although axial elongation alone was effective in predicting myopia onset (AUC >0.90), combining it with cycloplegic SE increased the AUC (>0.98) for predicting myopia onset.</p><p><strong>Conclusions: </strong>Annual AL change may serve as a clinically relevant threshold for monitoring pre-myopia risk in children.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of uncorrected refractive errors on eye-related quality of life and functional vision in a cohort of African children.","authors":"Michael Ntodie, Dennis Quarshie, Prince Mordi, Kwame Osei Okyere, Samuel Abokyi, Augustine N Nti","doi":"10.1111/opo.13529","DOIUrl":"https://doi.org/10.1111/opo.13529","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the impact of refractive errors on functional vision and eye-related quality of life (QoL) in a cohort of African children, using the Pediatric Eye Questionnaire (PedEyeQ).</p><p><strong>Methods: </strong>A comparative cross-sectional study was conducted involving 169 children aged 5-17 years (97 with refractive errors and 72 visually normal controls) and their parents/guardians. Refractive errors were classified based on cycloplegic refraction. The PedEyeQ was administered through interviewer-assisted sessions to assess functional vision and psychosocial well-being across child, proxy and parent-reported domains. Statistical analyses were conducted using Mann-Whitney U-tests for group comparisons and Kruskal-Wallis tests for subgroup analyses, with Bonferroni corrections applied for multiple comparisons.</p><p><strong>Results: </strong>Children with refractive errors had significantly lower PedEyeQ scores across all domains compared with controls (p < 0.01). Among refractive error types, astigmatism showed the most pronounced deficits in functional vision and psychosocial well-being. For children aged 5-11 years, median functional vision scores were 50 (43.7-70.0) for refractive error versus 90 (67.5-95.0) for the controls. Similarly, for children aged 12-17 years, the respective scores were 65 (45.0-75.0) and 90 (75.0-95.0). Proxy and parent-reported domains demonstrated similar findings, highlighting substantial impacts on family QoL and parental concerns.</p><p><strong>Conclusion: </strong>Refractive errors, particularly astigmatism, impair functional vision and eye-related QoL severely in African children and their families, suggesting a need for early detection and correction to improve outcomes for these children.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of preterm birth, retinopathy of prematurity and perinatal factors on corneal aberrations in adulthood: Results from the Gutenberg prematurity eye study.","authors":"Achim Fieß,&nbsp;Lina Amalia Berger,&nbsp;Jana C Riedl,&nbsp;Eva Mildenberger,&nbsp;Michael S Urschitz,&nbsp;Ulrike Hampel,&nbsp;Joanna Wasielica-Poslednik,&nbsp;Fred Zepp,&nbsp;Bernhard Stoffelns,&nbsp;Norbert Pfeiffer,&nbsp;Alexander K Schuster","doi":"10.1111/opo.13038","DOIUrl":"https://doi.org/10.1111/opo.13038","url":null,"abstract":"<p><strong>Introduction: </strong>Prematurity and retinopathy of prematurity (ROP) are associated with altered corneal shape and reduced visual acuity in childhood, but their long-term effects on corneal shape in later life are still unclear. This study evaluated whether prematurity and related perinatal factors are associated with corneal aberrations in adulthood.</p><p><strong>Methods: </strong>The Gutenberg Prematurity Eye Study (GPES) is a cohort study using Scheimpflug imaging of the cornea. Associations were assessed between corneal Zernike aberrations and gestational age (GA), birth weight (BW), BW percentile, ROP occurrence, ROP treatment and other perinatal factors using univariate and multivariable linear regression analyses.</p><p><strong>Results: </strong>This study involved 444 eyes of 256 individuals born preterm (aged 28.1 ± 8.4 years, 146 females) and 231 eyes of 132 individuals born full-term (aged 29.8 ± 8.9 years, 77 females). Multivariable analyses revealed an association between corneal higher-order aberrations and lower birth weight percentile (B = -0.001, p < 0.001) as well as ROP treatment (B = 0.120, p = 0.03). Corneal lower-order aberrations were also associated with lower birth weight percentile (B = -0.004; p = 0.001) and ROP treatment (B = 0.838, p = 0.01) but not with ROP occurrence. Increased corneal aberrations were correlated with lower visual acuity and the spherical equivalent refractive error.</p><p><strong>Conclusions: </strong>Perinatal factors, particularly low birth weight percentile and ROP treatment lead to a more irregular corneal shape in adulthood, thereby reducing optical image quality and potentially contributing to reduced visual acuity and altered refractive error.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":"1379-1389"},"PeriodicalIF":2.9,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40638800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Activation of lesion projection zone in primary visual cortex is dependent on bilateral central vision loss in patients with end-stage glaucoma.","authors":"Wenqing Zhu,&nbsp;Tingting Liu,&nbsp;Mengwei Li,&nbsp;Xinghuai Sun,&nbsp;Sheng He","doi":"10.1111/opo.13044","DOIUrl":"https://doi.org/10.1111/opo.13044","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate activation of the lesion projection zone (LPZ) in the primary visual cortex during end-stage glaucoma using functional magnetic resonance imaging (fMRI), as well as the relationship between fMRI responses and clinical data.</p><p><strong>Methods: </strong>Twelve subjects with bilateral end-stage glaucoma (group A), 12 with unilateral end-stage glaucoma (group B) and 12 healthy controls (group C) were enrolled. fMRI was performed under two testing stimuli conditions: passive viewing of a full-field flickering checkerboard and active viewing of a one-back task with scene images. In fMRI analysis, the primary visual cortex was divided into six regions of interest (ROIs). The beta values of the six ROIs were compared across the three groups using one-way analysis of variance under two viewing conditions. Associations between the fMRI beta value and clinical data including multifocal electroretinogram (mfERG), microperimeter-1 and optical coherence tomography were analysed by Spearman correlation.</p><p><strong>Results: </strong>The beta values for ROIs 1-3 representing the LPZ were significantly different between the three groups under active viewing conditions, whereas no significant changes were detected under passive viewing. In group A, there were significant differences between all six ROIs for the two viewing conditions, while no significant differences were found in groups B and C. In group A, the P-wave amplitudes of the mfERG was significantly correlated with the beta values of ROIs 1 and 2 under active viewing. In addition, the P-wave latencies of the mfERG were significantly correlated with the beta values for ROIs 2-5. No associations were found between fMRI beta values and clinical data in groups B and C.</p><p><strong>Conclusions: </strong>Activation of the LPZ in the primary visual cortex was observed in patients with bilateral end-stage glaucoma under active viewing conditions. These changes were correlated with residual retinal function.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":"1159-1169"},"PeriodicalIF":2.9,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40333566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The synergistic efficacy and safety of combined low-concentration atropine and orthokeratology for slowing the progression of myopia: A meta-analysis.","authors":"Ning-Ning Zheng,&nbsp;Kai-Wen Tan","doi":"10.1111/opo.13029","DOIUrl":"https://doi.org/10.1111/opo.13029","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the efficacy and safety of combined low-concentration atropine and orthokeratology (OK) for slowing the progression of myopia.</p><p><strong>Methods: </strong>We performed a systematic search of English and Chinese databases to collect potentially eligible randomised controlled trials (RCTs), nonrandomised controlled trials (non-RCTs) and retrospective cohort studies (REs) published between the establishment of the database and 1 January 2022. The weighted mean difference (WMD) and 95% confidence interval (CI) were calculated for each outcome.</p><p><strong>Results: </strong>Fifteen studies were ultimately included in the meta-analysis, which indicated that compared with OK lenses alone, the combination of low-concentration atropine with OK lenses significantly slowed axial growth (WMD = -0.12 mm; 95% CI: -0.13 to -0.11, p < 0.001) and reduced the rate of change of the spherical equivalent refraction (WMD = 0.15 D; 95% CI: 0.06 to 0.24, p < 0.001). Additionally, the combined treatment may cause a slight increase in pupil diameter (WMD = 0.62 mm; 95% CI: 0.42 to 0.81, p < 0.001). No significant difference in the amplitude of accommodation, intraocular pressure, tear film break-up time or corneal endothelial cell density was found between the OK and combination therapy groups.</p><p><strong>Conclusions: </strong>The combination therapy of low-concentration atropine and OK lenses had a greater effect in slowing myopia progression during a 6-to-12-month treatment interval and was still effective over a 24-month period. Increased pupil diameter was the major side effect of the combination therapy, with no negative impact on the amplitude of accommodation, intraocular pressure, tear film break-up time or corneal endothelial cell density.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":"1214-1226"},"PeriodicalIF":2.9,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40596090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optometry independent prescribing during COVID lockdown in Wales.","authors":"Paul Cottrell,&nbsp;Rachel North,&nbsp;Nik Sheen,&nbsp;Barbara Ryan","doi":"10.1111/opo.13028","DOIUrl":"https://doi.org/10.1111/opo.13028","url":null,"abstract":"<p><strong>Introduction: </strong>During the COVID-19 lockdown, primary care optometry services in Wales moved to a hub model of provision. Three independent prescribing models were available in different areas: a commissioned Independent Prescribing Optometry Service (IPOS), independent prescribers that were not commissioned and no independent prescribers available. This allowed a unique opportunity for comparison.</p><p><strong>Method: </strong>Optometry practices completed an online survey for each patient episode. Analysis of the data gave insight into patient presentation to urgent eye services and the drugs prescribed by optometrists. Medicines prescribed, sold or given and onward referral were compared between areas with an IPOS service (n = 2), those with prescribers but no commissioned service (n = 2) and those with no prescribers (n = 2).</p><p><strong>Results: </strong>Data from 22,434 reported patient episodes from 81 optometry practices in six health boards between 14 April 2020 and 30 June 2020 were analysed. Urgent care accounted for 10,997 (49.02%) first appointments and 1777 (7.92%) follow-ups. Most (18,006, 80.26%) patients self-referred. The most common presenting symptom was 'Eye pain/discomfort' (4818, 43.81% of urgent attendances). Anterior segment pathology was the most reported finding at first (6078, 55.27%) and follow-up (1316, 74.06%) urgent care appointments. Topical steroids (373, 25.99% of prescriptions) were the most prescribed medications. More medications were prescribed in areas with an IPOS service (1136, 79.16% of prescriptions) than areas with prescribers but no commissioned service. There were more follow-up appointments in optometric practice and fewer urgent referrals to ophthalmology in IPOS areas.</p><p><strong>Conclusion: </strong>Urgent care services were most utilised by patients with discomfort caused by anterior eye conditions. IPOS services enabled optometrists to manage conditions to resolution without referral and without reduction in medications sold or given. Commissioners should recognise the value in reducing burden in urgent ophthalmology and the need for follow-up as part of a commissioned independent prescribing service.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":"1289-1303"},"PeriodicalIF":2.9,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40606719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A brief light reduction induces a significant delay in the previously dimmed eye.","authors":"Seung Hyun Min,&nbsp;Alexandre Reynaud,&nbsp;Robert F Hess","doi":"10.1111/opo.13033","DOIUrl":"https://doi.org/10.1111/opo.13033","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated how a short-term luminance reduction in one eye can influence temporal processing of that eye after luminance is restored by measuring the relative delay between the eyes.</p><p><strong>Methods: </strong>A paradigm based on the Pulfrich effect, which is a visual illusion of depth when no depth cue is present, was used to measure relative delay in visual processing between the eyes. We deprived the monocular luminance in adults with normal vision across different intensities. In the first experiment, the ratio of the light level between the eyes stayed constant, whereas the absolute value was allowed to vary. In the second experiment, both the ratio and the absolute light level stayed constant, by controlling the environmental light level. In both experiments, we measured the changes in relative delay before and after 60 min of light deprivation.</p><p><strong>Results: </strong>Our results indicated that short-term monocular deprivation of luminance slows the processing in the previously dimmed eye and that the magnitude of the delay is correlated with the degree of luminance reduction. In addition, we observed that the absolute luminance difference, rather than the absolute luminance levels seen by the dimmed eye, is important in determining the magnitude of delay in the previously dimmed eye. These findings differ from what has been reported previously for the monocular deprivation of contrast.</p><p><strong>Conclusions: </strong>Taken together, these findings support the view that short-term deprivation of visual information could affect two distinct mechanisms (contrast gain and temporal dynamics) of neural plasticity.</p>","PeriodicalId":520731,"journal":{"name":"Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)","volume":" ","pages":"1399-1409"},"PeriodicalIF":2.9,"publicationDate":"2022-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40656532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}