高度非球面晶状体与平面晶状体在近视前期儿童中的实际疗效:一项前瞻性队列研究。

IF 2.4
Aimin Sun, Xueli Li, Pingping Zhu, Fenghua Xie, Yuan Wu
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引用次数: 0

摘要

目的:评价平面晶状体(PLs)与高度非球面晶状体(HALs)在控制近视前儿童眼轴长(AL)发展中的作用。方法:这项前瞻性队列研究招募了103名6-12岁的儿童,他们的球面等效折射(SE)在-0.50到+0.75 d之间。参与者被分配到佩戴带有hal的PLs的治疗组或不接受干预的对照组。分别在基线(V0)、3个月(V1)、6个月(V2)和12个月(V3)测量AL和SE。计算V0-V1、V1-V2和V2-V3区间AL的月变化。采用重复测量-方差分析来分析组内和组间AL随时间间隔的变化。结果:共有95名儿童(8.0±1.4岁)完成研究,其中治疗组46名,对照组49名。12个月后,治疗组近视进展(0.13±0.12 D)明显少于对照组(0.43±0.16 D);结论:PL/ hal可有效控制近视前期儿童AL生长,且在配戴后3个月内影响最显著。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Real-world efficacy of plano lenses with highly aspherical lenslets in children with pre-myopia: A prospective cohort study.

Purpose: To assess the efficacy of plano lenses (PLs) with highly aspherical lenslets (HALs) in controlling axial length (AL) progression in pre-myopic children.

Methods: This prospective cohort study enrolled 103 children aged 6-12 years with a spherical equivalent refraction (SE) between -0.50 and +0.75 D. Participants were assigned to either a treatment group wearing PLs with HALs or a control group receiving no intervention. AL and SE were measured at baseline (V0), 3 months (V1), 6 months (V2) and 12 months (V3). Monthly changes in AL were calculated for V0-V1, V1-V2 and V2-V3 intervals. Repeated measures-ANOVA was performed to analyse AL changes across time intervals within and between groups.

Results: A total of 95 children (8.0 ± 1.4 years) completed the study, with 46 in the treatment group and 49 in the control group. After 12 months, the treatment group showed significantly less myopic progression (0.13 ± 0.12 D) compared with the control group (0.43 ± 0.16 D; p < 0.01). AL elongation was also lower in the treatment group than in the control group (0.16 ± 0.16 mm vs. 0.30 ± 0.16 mm; p < 0.001). Monthly AL changes remained consistently lower in the treatment group across all intervals. In the treatment group, the monthly AL change was notably lower in V0-V1 than in either V1-V2 or V2-V3, whereas there were no comparable significant differences in the control group.

Conclusion: PL/HALs can effectively control AL growth in pre-myopic children, with the most significant impact occurring within the first 3 months of wear.

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