Case Reports in Cardiology最新文献

{"title":"Anterior ST-Segment Elevation From Nondominant Right Coronary Artery Occlusion: Lessons From Two Cases.","authors":"Hadeel Ayesh, Mohammad Al-Shaer, Shoukri Alsleibi","doi":"10.1155/cric/3860471","DOIUrl":"10.1155/cric/3860471","url":null,"abstract":"<p><p>Acute occlusion of a nondominant right coronary artery (RCA) is an uncommon but clinically significant cause of anterior ST-segment elevation that may mimic anterior ST-segment elevation myocardial infarction (STEMI) and pose a diagnostic challenge in identifying the culprit vessel during emergent coronary angiography. We report two patients presenting with anterior ST-segment elevation in whom emergent coronary angiography revealed acute occlusion of a nondominant RCA with right ventricular branch compromise. In both cases, chest pain and ST-segment elevation improved immediately after RCA reperfusion and before intervention on other coronary lesions. These cases highlight the importance of recognizing this atypical presentation and carefully assessing coronary anatomy to identify the culprit vessel and guide timely revascularization.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"3860471"},"PeriodicalIF":0.5,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13575486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148978658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fatal Intracardiac Embolism Following Cement-Augmented Pedicle Screw Instrumentation: A Case Report.","authors":"Raul Eduardo Reyes Toledo, Laura Catalina Arcos, Jorge Alberto Carrillo","doi":"10.1155/cric/7883797","DOIUrl":"10.1155/cric/7883797","url":null,"abstract":"<p><strong>Background: </strong>Cement-augmented pedicle screw instrumentation (CAPSI) is a widely used surgical technique for spinal stabilization and decompression, particularly in patients with poor bone quality. Although generally considered safe, cement extravasation can result in severe complications, including neurological injury and embolic events involving pulmonary or cardiac structures. Intracardiac cement embolism is a rare but potentially fatal occurrence.</p><p><strong>Case presentation: </strong>A 67-year-old man with a history of hypertension and advanced renal cancer under palliative care presented with a 1-week history of severe lumbar pain radiating to the right lower limb, accompanied by progressive weakness in both legs. Magnetic resonance imaging revealed an infiltrative soft tissue mass extending from T12 to L2 with spinal canal compression and metastatic-appearing sacroiliac bone lesions. The patient underwent open posterior decompression with CAPSI using polymethylmethacrylate. Within 24 h postoperatively, he developed acute dyspnea and oppressive retrosternal chest pain. A contrast-enhanced chest CT revealed hyperdense material consistent with cement within the inferior vena cava, pulmonary arteries, and right ventricle, with perforation of the posterior ventricular wall and extravasation into the anterior esophageal wall. Transesophageal echocardiography confirmed a 53-mm linear, hyperechoic structure spanning the right atrium and perforating the anterior leaflet of the tricuspid valve, resulting in significant tricuspid regurgitation. A second cement fragment, located outside the atrial cavity, was associated with a mild pericardial effusion. Surgical intervention was recommended but declined by the patient. He subsequently developed obstructive shock due to cardiac tamponade and died.</p><p><strong>Discussion: </strong>This case highlights a rare but catastrophic complication of CAPSI. Accidental cement migration into the venous system can lead to cardiac perforation, even after an apparently uneventful surgical procedure. Prompt clinical suspicion and multimodal imaging are critical to identifying and managing this potentially fatal condition.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"7883797"},"PeriodicalIF":0.5,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Tropheryma whipplei</i>: A Cause of Rapidly Fatal Prosthetic Valve Endocarditis Despite a Classically Indolent Disease Course.","authors":"Abdallatif Dawoud, Mohammad Safi, Maddy Taylor, Raghad Elhag, Oun Al-Dalahmeh, Omar Horani, Li Wang, Samer J Khouri","doi":"10.1155/cric/1675151","DOIUrl":"10.1155/cric/1675151","url":null,"abstract":"<p><strong>Background: </strong><i>Tropheryma whipplei</i> (<i>T. whipplei</i>) is a rare cause of culture-negative infective endocarditis and may present without classic gastrointestinal manifestations, leading to delayed diagnosis and severe valvular destruction.</p><p><strong>Case summary: </strong>A 76-year-old man with a prior bioprosthetic aortic valve replacement presented with at least 2 weeks of fatigue, generalized weakness, intermittent chills, and worsening dyspnea, along with approximately 8 kg of unintentional weight loss since the preceding summer; he remained afebrile. Blood cultures remained persistently negative. Transesophageal echocardiography revealed a > 3-cm vegetation, prosthetic valve dehiscence, severe paravalvular regurgitation, and periannular abscess. Despite empiric broad-spectrum antibiotics and urgent surgical evaluation, the patient deteriorated and suffered cardiac arrest. Whole-blood polymerase chain reaction testing collected during hospitalization returned positive for <i>T. whipplei</i> after the patient's death, establishing the diagnosis.</p><p><strong>Discussion: </strong>Whipple endocarditis typically presents as culture-negative disease and often lacks systemic features, delaying recognition. This case highlights the diagnostic challenge posed by <i>T. whipplei</i> in prosthetic valve endocarditis and the value of molecular testing when conventional cultures remain negative.</p><p><strong>Take‐home message: </strong>Early PCR testing should be considered in culture-negative prosthetic endocarditis, as it may establish a diagnosis when conventional cultures and valve tissue are unavailable.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"1675151"},"PeriodicalIF":0.5,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13570416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Hidden Cost of Immunity: Myocarditis Presenting as Complete Heart Block in an Older Adult Following COVID-19 Booster.","authors":"Dhan Bahadur Shrestha, Ruvarashe Mupedziswa, Daniel H Katz, Mustafain Meghani","doi":"10.1155/cric/4549069","DOIUrl":"10.1155/cric/4549069","url":null,"abstract":"<p><strong>Background: </strong>Myocarditis has been rarely reported following COVID-19 vaccination, most commonly in younger males. Although a temporal association has been observed, establishing causality in individual cases remains challenging. Myocardial inflammation may involve the cardiac conduction system, rarely resulting in high-grade atrioventricular (AV) block. Importantly, these conduction abnormalities may be transient and resolve as the underlying inflammation improves.</p><p><strong>Case summary: </strong>We report a rare case of myocarditis following a COVID-19 vaccination in an elderly woman who experienced complete heart block and worsening exertional dyspnea subsequent to receiving a COVID-19 booster. Coronary angiography revealed patent coronary arteries, and magnetic resonance imaging confirmed the presence of myocarditis. Her conduction abnormality progressively resolved without the need for permanent pacing, and she was subsequently discharged in stable condition.</p><p><strong>Discussion: </strong>Myocarditis should be considered as a potentially reversible cause of high-grade AV block. A thorough clinical history and multimodal imaging are essential for diagnosis, as early recognition and appropriate monitoring may allow recovery of AV conduction and avoid unnecessary permanent pacemaker implantation.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"4549069"},"PeriodicalIF":0.5,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13551587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148914362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tricuspid Valve Infective Endocarditis With Biventricular Thrombi: An Unusual Presentation.","authors":"Genevieve Phipps, Sarteg Singh, Shane Preston","doi":"10.1155/cric/2016181","DOIUrl":"10.1155/cric/2016181","url":null,"abstract":"<p><strong>Background: </strong>Biventricular thrombi (BVT) is a rare presentation associated with high morbidity and mortality due to the potential sequela of life-threatening complications including embolic events and cardiac failure. As an uncommon entity, there is limited research on best practice for the management of BVT.</p><p><strong>Presentation: </strong>We present a case of BVT with <i>Streptococcus anginosus</i> and <i>Staphylococcus hominis</i> concomitant bloodstream infection, tricuspid valve infective endocarditis (TVIE), septic emboli and decompensated dilated cardiomyopathy (LVEF 20%-25%). Guideline directed heart failure management, antimicrobials and anticoagulation were initiated with a remarkable recovery within 2 months.</p><p><strong>Discussion: </strong>Given the rarity of this presentation, a multidisciplinary approach was taken to guide management. Follow-up echocardiography after completion of antimicrobial therapy demonstrated an LVEF of 53%, no detectable thrombus and resolution of congestive symptoms. Although there is minimal population-based evidence, this case supports a conservative approach for the treatment of TVIE, BVT and its potential sequelae in select patients.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"2016181"},"PeriodicalIF":0.5,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13554727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three-Dimensional Printing of Cardiac Reconstruction, Facilitating Customized Closure Device of Gigantic Left Atrial Appendage: Case Report.","authors":"Mann Chandavimol, Tawai Ngernsritrakul, Krissada Meemook, Kakanand Srungboonmee, Thinnakrit Sasiprapha, Thanakhom Hoontrakul","doi":"10.1155/cric/7409635","DOIUrl":"10.1155/cric/7409635","url":null,"abstract":"<p><p>We present a successful case of 3D printed cardiac reconstruction for a custom-made LAAO LAmbre (Lifetech Scientific Corp., Shenzhen, China) device of gigantic and challenging LAA anatomy.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"7409635"},"PeriodicalIF":0.5,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148908107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epicardial Lipomatosis as a Cause of Constrictive Pericarditis.","authors":"Punam Ajay Raval, John Otieno Odhiambo, Kevin Ombati, Barbara Karau, Leonard Mzee Ngunga","doi":"10.1155/cric/1335322","DOIUrl":"10.1155/cric/1335322","url":null,"abstract":"<p><p>Epicardial lipomatosis is a rare cause of constrictive pericarditis. There is a paucity of literature on the condition, and it is possible that it may be missed in contemporary clinical practice. Herein, we report two patients with epicardial lipomatosis who presented with traditional cardiovascular risk factors. After an initial suspicion of pericardial effusion, both patients underwent multimodality imaging with transthoracic echocardiography, computed tomography, and cardiac magnetic resonance imaging, which demonstrated diffuse epicardial fat. Conservative management was pursued in both cases with optimization of heart failure therapy and the dialysis strategy, resulting in clinical improvement.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"1335322"},"PeriodicalIF":0.5,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13547838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148908120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular and Cerebrovascular Complications Following Ponatinib for Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia.","authors":"Catherine Boldig, Andrew Herson, Justin Falk, Mitchell Boshkos, David Z Rose","doi":"10.1155/cric/3296809","DOIUrl":"10.1155/cric/3296809","url":null,"abstract":"<p><p>Ponatinib is a third-generation BCR:ABL1 tyrosine kinase inhibitor used in selected patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), particularly those with T315I mutations, or disease resistant, or those intolerant to prior tyrosine kinase inhibitors. Although effective, ponatinib has been associated with arterial occlusive events. We report a 63-year-old man with Ph+ ALL who, while receving ponatinib, developed a myocardial infarction requiring quadruple coronary artery bypass grafting, followed by symptomatic intracranial arterial stenosis necessitating superficial temporal artery to middle cerebral artery bypass. Despite multiple cardiovascular risk factors, the chronology of progressive coronary and cerebral vascular disease raised suspicion for ponatinib-associated vasculopathy, although causality cannot be established. To our knowledge, this is the first reported case of sequential coronary and cerebral surgical revascularization occurring during ponatinib therapy. This case highlights the importance of careful cardiovascular surveillance, multidisciplinary management, and individualized risk-benefit assessment in patients treated with ponatinib.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"3296809"},"PeriodicalIF":0.5,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13533073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148876467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Holt-Oram Syndrome With Complex Cardiac and Limb Anomalies in an Ethiopian Patient: A Case Report.","authors":"Yitagesu Getachew, Abera Birhanu, Samson Mulugeta, Balew Arega, Begashaw Belay, Amdemeskel Mersha, Banchiaymolu Damtie, Abel Yirga, Eba Fufa, Ibrahim Kemal, Brook Fanuel","doi":"10.1155/cric/5488112","DOIUrl":"10.1155/cric/5488112","url":null,"abstract":"<p><strong>Introduction: </strong>Holt-Oram syndrome (HOS) is a rare autosomal dominant disorder characterized by upper limb and congenital heart anomalies, with an estimated incidence of 1 in 100,000 live births.</p><p><strong>Case report: </strong>An 18-year-old Ethiopian male with a history of congenital heart disease presented with progressive dyspnea and limb deformities. Imaging confirmed a membranous ventricular septal defect, severe pulmonary hypertension, mitral and tricuspid regurgitation, and skeletal anomalies, including thumb hypoplasia and absent distal radial bone.</p><p><strong>Conclusion: </strong>This case underscores the importance of early diagnosis and multidisciplinary management of HOS, especially in resource-limited settings where genetic testing is unavailable. Increased awareness can facilitate timely intervention and improve patient outcomes.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"5488112"},"PeriodicalIF":0.5,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13527633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148867938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dissecting the Delirium: A Case of Triple Vessel SCAD Secondary to Encephalitis.","authors":"Katie Doyle, Patrick Savage, Paul Johnston","doi":"10.1155/cric/4183983","DOIUrl":"10.1155/cric/4183983","url":null,"abstract":"<p><p>Spontaneous coronary artery dissection (SCAD) is an infrequently diagnosed cause of an acute coronary syndrome (ACS). In many cases, no clear precipitant is identified. In this case, we present a novel presentation of triple vessel SCAD in a patient presenting with viral encephalitis. Despite an initial conservative strategy, haemodynamic instability and involvement of the left main stem (LMS) ultimately necessitated emergent coronary intervention with a 'shotgun' LMS bifurcation strategy.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"4183983"},"PeriodicalIF":0.5,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13507925/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148834605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}