Case Reports in Cardiology最新文献

{"title":"Treatment of Early Trilogy Valve Aortic Insufficiency With Valve-in-Valve Transcatheter Aortic Valve Replacement.","authors":"Johan van Nispen, Michael Massoomi, Eric Jeng","doi":"10.1155/cric/6773549","DOIUrl":"10.1155/cric/6773549","url":null,"abstract":"<p><p>Aortic insufficiency (AI) is the third most common left valvular heart disease. Transcatheter aortic valve replacement (TAVR) is becoming popular in the treatment of AI. The Trilogy Valve (JenaValve Technology, Irvine, California, United States) is in clinical trials. We report here a case of valve-in-valve TAVR with a Sapien S3 Ultra Resilia valve (Edwards Lifesciences Corporation, Irvine, California, United States) for recurrent AI after Trilogy valve placement.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"6773549"},"PeriodicalIF":0.5,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13501502/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148814893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Explosive Multiterritorial Arterial Thrombosis Following Brief Heparin Exposure: A Diagnostic Pitfall in the Cath Lab.","authors":"Justine Massart, Claudiu Ungureanu, Yves Dascotte, Jacques Auslender, Adrien Jossart","doi":"10.1155/cric/6999917","DOIUrl":"10.1155/cric/6999917","url":null,"abstract":"<p><strong>Background: </strong>Type II heparin-induced thrombocytopenia (HIT) is a catastrophic immunothrombotic disorder that can be triggered by minimal heparin exposure during routine coronary angiography.</p><p><strong>Case summary: </strong>A 67-year-old woman developed \"explosive\" multiterritorial arterial thrombosis-including acute limb ischemia, an inferior STEMI, and a stroke-within minutes of receiving 5000 units of intra-arterial heparin. This followed a brief nadroparin exposure 8 days prior. Crucially, events occurred while platelet counts were still normal. Despite a negative functional assay, a high 4T score (6 points) confirmed HIT. Management involved non-heparin anticoagulation (danaparoid sodium) and thrombectomies.</p><p><strong>Discussion: </strong>This case highlights a major diagnostic pitfall: severe arterial thrombosis preceding overt thrombocytopenia. The immediate \"anaphylactoid-like\" reaction following a heparin bolus is often misidentified as contrast allergy, delaying life-saving intervention.</p><p><strong>Take home messages: </strong>Suspect HIT in acute systemic reactions or multifocal thrombosis after heparin exposure, regardless of initial platelet counts.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"6999917"},"PeriodicalIF":0.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13488371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful Transcatheter Amplatzer Repair of Severe Paravalvular Leak Following Mechanical Mitral Valve Replacement Surgery.","authors":"Akash Ramanathan, Sukesh Burjonroppa, Jeffery Wu, Mohanakrishnan Sathyamoorthy","doi":"10.1155/cric/9949348","DOIUrl":"10.1155/cric/9949348","url":null,"abstract":"<p><strong>Introduction: </strong>Paravalvular leaks are a rare complication following surgical mitral valve replacement but may result in significant mitral regurgitation. In patients with paravalvular leak, percutaneous repair of the leak is an emerging option for patients who are poor surgical candidates. This report presents a case of a severe symptomatic paravalvular leak postsurgical mitral replacement that was treated with a transcatheter approach resulting in complete resolution of paravalvular regurgitation and symptoms.</p><p><strong>Case description: </strong>A 60-year-old male with a history of atrial fibrillation, nonischemic cardiomyopathy, Stage III chronic kidney disease, and heart failure with a mildly reduced ejection fraction that improved after undergoing mechanical mitral valve replacement presented with recurrent shortness of breath a few months after surgery. Transthoracic echocardiography demonstrated severe paravalvular leak, with a subsequent TEE confirming the precise etiology and location. After collaborative evaluation in a multidisciplinary valve clinic, the patient underwent successful transcatheter closure with Amplatzer plugs.</p><p><strong>Discussion: </strong>Transcatheter valve interventions are minimally invasive techniques that have emerged as therapeutic options for patients who are poor surgical candidates. Using this approach to manage PVL is now being studied as a treatment option for patients to avoid redo mitral surgery. This case presents a transcatheter approach to PVL closure in a patient who had undergone a previous surgical mitral valve replacement, resulting in complete resolution of symptoms. The effectiveness of this transcatheter approach signals the need for larger prospective or registry studies to refine transcatheter approaches to manage postsurgical mitral paravalvular leaks.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"9949348"},"PeriodicalIF":0.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13487460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct Intravascular Observation of Trifecta️ Bioprosthetic Valve Dysfunction Using Nonobstructive General Angioscopy.","authors":"Jumpei Suzuki, Tsuyoshi Kobayashi, Toru Yoshizaki, Akira Sato","doi":"10.1155/cric/7201873","DOIUrl":"10.1155/cric/7201873","url":null,"abstract":"<p><p>Although surgical reintervention remains the standard of care for failed surgical valves, transcatheter aortic valve implantation in surgical aortic valves (TAV-in-SAV) has emerged as a viable alternative with reliable results. The Trifecta valve is one of the most challenging SAVR prostheses for TAV-in-SAV management. Recently, nonobstructive general angioscopy (NOGA) has been used to evaluate the quality of plaques on the inner surface of the aorta under direct visualization, which cannot be evaluated using computed tomography. Here, we describe a case of Trifecta️ bioprosthetic valve dysfunction (BVD) directly observed by NOGA. A 26-mm Evolut FX was implanted, and the procedure was completed without complications. This case highlights the potential adjunctive role of NOGA in the assessment of BVD; however, its incremental clinical benefit and safety profile require further investigation.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"7201873"},"PeriodicalIF":0.5,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13487812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aortic Atresia With Ventricular Septal Defect and Normal-Sized Left Ventricle Mimicking Truncus Arteriosus.","authors":"Chun-Lok Ho, Pak-Cheong Chow","doi":"10.1155/cric/7706714","DOIUrl":"10.1155/cric/7706714","url":null,"abstract":"<p><strong>Background: </strong>Aortic atresia is typically associated with a hypoplastic left ventricle and mitral valve. Rarely, the left ventricle is normal-sized with a concomitant unrestrictive ventricular septal defect (VSD), which can resemble truncus arteriosus when the ascending aorta is rudimentary.</p><p><strong>Case: </strong>A term infant with an antenatal diagnosis of truncus arteriosus was delivered uneventfully. Initial echocardiography revealed balanced ventricles, an unrestrictive VSD, and a single outlet with a dominant arterial trunk giving rise to both pulmonary arteries and continuing to the descending aorta but with an unusual craniobrachial branching pattern. Computed tomography (CT) additionally showed narrowing of this arterial trunk proximal to the descending aorta. The infant deteriorated rapidly despite intravenous prostaglandin and dopamine infusion. Emergency surgery was performed to establish an unobstructed aortic arch. Postoperatively, the infant required extracorporeal membrane oxygenation and developed multiorgan failure. Given the poor prognosis, comfort care was adopted and the infant died. Retrospective review of the echocardiography and CT angiogram suggested aortic atresia with a rudimentary ascending aorta and severe coarctation. The presumed arterial trunk was in fact the dilated pulmonary artery connected to the descending aorta through the ductus arteriosus.</p><p><strong>Conclusions: </strong>Aortic atresia with an unrestrictive VSD and a normal-sized left ventricle can mimic truncus arteriosus. Timely differentiation is pivotal to improving outcomes.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"7706714"},"PeriodicalIF":0.5,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13482180/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right-Sided Dual-Chamber Left Bundle Branch Area Pacing in Persistent Left Superior Vena Cava: A Case Report on Personalized Conduction System Pacing.","authors":"Dhan Bahadur Shrestha, Ashlesha Chaudhary, Aamir Gilani, Jurgen Shtembari, James A Storey","doi":"10.1155/cric/9833282","DOIUrl":"10.1155/cric/9833282","url":null,"abstract":"<p><strong>Background: </strong>Persistent left superior vena cava (PLSVC) can complicate transvenous device implantation due to challenging venous anatomy and limited sheath support during physiologic pacing lead delivery.</p><p><strong>Case summary: </strong>A woman in her mid-40s evaluated for a syncopal episode had ambulatory electrocardiography showing high-grade atrioventricular block with prolonged pauses, deemed irreversible, leading to plans for a permanent pacemaker. Intraprocedural venography identified a PLSVC. A right-sided dual chamber left bundle branch area pacing (LBBAP) was successfully performed. The procedure was uncomplicated, and follow-up with cardiology was arranged.</p><p><strong>Discussion: </strong>Right-sided LBBAP can be feasible and associated with positive outcomes in patients with PLSVC, and it should be considered a strong option when traditional venous routes are difficult. Early detection and adaptable pacing strategies are essential for maximizing outcomes in such patients.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"9833282"},"PeriodicalIF":0.5,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13482179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rare Cause of Restrictive Cardiomyopathy: A Case Report of Löffler Endocarditis.","authors":"Jose L Diz Ferre, Edward G Soltesz, Agostina Fava","doi":"10.1155/cric/5307648","DOIUrl":"10.1155/cric/5307648","url":null,"abstract":"<p><p>Löffler endocarditis, an idiopathic hypereosinophilic syndrome, can present symptoms of heart failure and peripheral eosinophilia. We present the case of a 46-year-old woman with fatigue, shortness of breath, and edema, who was found to have thrombocytopenia, elevated cardiac biomarkers, and hypereosinophilia (2.96 k/uL). Cardiac MRI revealed hypertrophic cardiomyopathy, right ventricular hypertrophy, and a restrictive filling pattern, raising suspicion for Löffler endocarditis. Despite initial corticosteroid and diuretic treatment, she was readmitted with persistent symptoms. This case highlights the diagnostic imaging and treatment challenges with corticosteroid therapy, to control eosinophilic infiltration and prevent irreversible cardiac damage. Löffler endocarditis should be considered in the imaging differential diagnosis of unexplained heart failure.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"5307648"},"PeriodicalIF":0.5,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13478794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiogenic Versus Obstructive Shock as a Consequence of Road Traffic Accidents: A Case Report on Approach.","authors":"Azri Salih Haji Sgery, Philip Fathil Essa, Dilbar Lhon Sultan, Ahmed Mohammed Sharif, Abdullah Ibrahim Mohammed","doi":"10.1155/cric/9592779","DOIUrl":"10.1155/cric/9592779","url":null,"abstract":"<p><strong>Background and introduction: </strong>Cardiac tamponade is a medical/traumatic emergency characterized by the increased intrapericardial pressure from the accumulation of excessive fluid (either exudate, transudate, or blood) in the pericardium. Emergency sonography is a vital part of the rapid assessment of cases with traffic accidents and chest traumas, as pericardial injuries are among the hidden affected organs. Here, we present a case of successful resuscitation of cardiac tamponade.</p><p><strong>Case presentation: </strong>An 18-year-old male presented as a case of a traffic accident within 30 min with hemodynamic instability from bradycardia, hypotension, decreased Glasgow Coma Scale, and distended jugular venous pressure. Bilateral air entry was present, with the aid of E-FAST, tension pneumothorax was excluded, and cardiac tamponade was diagnosed. Immediately, needle pericardiocentesis was done under the supervision of a senior traumatologist, followed by rapid improvement. A central venous line was inserted in the pericardium for continuous drainage. A total of 810 mL of blood and serosanguineous fluid were drained. The patient was discharged home after 4 days of intensive care stay and 1 day in the ward.</p><p><strong>Discussion: </strong>Beck's triad, along with bradycardia, indicates cardiac tamponade until proven otherwise. Any case presenting with features of hypotension, especially following trauma to the chest, should have tamponade excluded by using E-FAST. Needle pericardiocentesis is a life-saving procedure that can provide immediate relief through aspiration of the pressure.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"9592779"},"PeriodicalIF":0.5,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13479348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refractory Intraprocedural Ventricular Fibrillation From Left Circumflex Culprit Occlusion Managed With Culprit PCI and Short-Duration Impella Support.","authors":"Vineet Madishetty, Alexander Yaylayan, Kevin Schneider, Varun Yelamanchili, Merrill Krolick","doi":"10.1155/cric/2641470","DOIUrl":"10.1155/cric/2641470","url":null,"abstract":"<p><strong>Background: </strong>Ventricular fibrillation (VF) is a life-threatening complication of acute coronary syndrome (ACS) and requires rapid identification and correction of reversible ischemic triggers. ST-segment elevation in aVR with diffuse ST depression reflects global subendocardial ischemia but is not specific for left main or proximal left anterior descending disease.</p><p><strong>Case summary: </strong>A 62-year-old male with prior coronary stent placement presented with acute chest pain, diaphoresis, nausea, and vomiting. An electrocardiogram demonstrated ST-segment elevation in aVR with ST depressions in V3-V6. Laboratory testing demonstrated severe metabolic acidosis (pH 7.07; bicarbonate 10.3 mEq/L), lactate 3.7 mmol/L, and high-sensitivity troponin rising from 427 to 4991 ng/L within 2 h. During emergent angiography, VF developed after left ventricular catheter manipulation and recurred repeatedly while attempting to cross a heavily calcified 99% proximal left circumflex (LCx) lesion. Over 20-30 min, 11 VF episodes required immediate defibrillation, manual chest compressions, and intravenous amiodarone. VF ceased only after LCx stenting restored TIMI Grade 3 flow. The patient's maximum intraprocedural shock severity met SCAI Stage E criteria because of recurrent cardiac arrest, multiple defibrillations, and severe acidosis. An Impella microaxial flow pump was placed for temporary postresuscitation circulatory support and maintained at P4. A postreperfusion echocardiogram obtained during ongoing support showed an LVEF of approximately 60%. The device was removed within 48 h after hemodynamic recovery. Staged intravascular lithotripsy-assisted PCI of the calcified mid-LAD lesion was performed on Day 4.</p><p><strong>Discussion: </strong>This case demonstrates that refractory ischemia-mediated VF may terminate only after culprit-vessel reperfusion. A preserved LVEF measured after reperfusion during mechanical support does not exclude earlier SCAI Stage E shock. Short-duration Impella support may serve as an individualized bridge during recovery from recurrent arrest and transient circulatory collapse.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"2641470"},"PeriodicalIF":0.5,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13482039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Classic Murmur, Unexpected Diagnosis: A Case Report and Pathophysiological Review.","authors":"José Maria Gonçalves Fernandes, Flávio Bonaparte Laranjeira, Margareth de Souza Lira Handro, Benício de Oliveira Romão, Francisco de Assis Costa, Ivan Romero Rivera, Maria Alayde Mendonça Rivera","doi":"10.1155/cric/3461386","DOIUrl":"10.1155/cric/3461386","url":null,"abstract":"<p><p>A systolic murmur best heard at the aortic area with radiation to the neck is considered a hallmark of aortic stenosis. We report a patient with this auscultatory pattern in whom investigation revealed an unexpected diagnosis. Accompanying symptoms reinforced the initial suspicion, adding another layer of complexity to the diagnostic process. This case highlights the limitations of relying solely on symptom profile and murmur topography, and underscores the importance of comprehensive physical examination and diagnostic imaging in evaluating valvular heart disease.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"3461386"},"PeriodicalIF":0.5,"publicationDate":"2026-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13478730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148801524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}