Case Reports in Cardiology最新文献

{"title":"Differentiating Mobile Masses on Transcatheter Aortic Valve: Thrombi or Vegetations?","authors":"Alexander Arreguin, Akash Goyal, Konstantinos Dean Boudoulas, Adam Potter, Timothy Obarski","doi":"10.1155/cric/9915565","DOIUrl":"10.1155/cric/9915565","url":null,"abstract":"<p><p>A 58-year-old female presented with new-onset dyspnea. Two years prior, she had undergone a transcatheter aortic valve replacement with a 26-mm Edwards Sapien 3 valve. Diagnostic testing included transthoracic and transesophageal echocardiograms that revealed increased transvalvular gradients and suspected prosthetic thrombosis. Laboratory testing included blood cultures that unexpectedly grew <i>Streptococcus sanguinis</i>. This case highlights the difficulty in differentiating prosthetic valve thrombosis from infective endocarditis and the possible therapeutic complications that could arise.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"9915565"},"PeriodicalIF":0.6,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12069840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heartbreak From Gilteritinib: Two Case Reports of Delayed Onset Cardiotoxicity.","authors":"Kristi Dutta, Ethan D Kotloff, Manu M Mysore","doi":"10.1155/cric/1976122","DOIUrl":"https://doi.org/10.1155/cric/1976122","url":null,"abstract":"<p><p>Activating mutations of FMS-like Tyrosine Kinase 3 (FLT3) occur in a subset of patients with acute myeloid leukemia (AML) and confer a poor prognosis. Gilteritinib, an oral FLT3 inhibitor approved for the treatment of relapsed or refractory AML, has been shown to improve survival and remission rates compared with salvage chemotherapy. This case report presents two patients initiated on gilteritinib for relapsed AML who developed new onset left ventricular systolic dysfunction. After ruling out other common etiologies, gilteritinib was discontinued due to concern for cancer therapy-related cardiac dysfunction with subsequent improvement in ejection fraction. These cases demonstrate a rare but serious adverse effect of gilteritinib, cardiotoxicity manifested as left ventricular systolic dysfunction, for which more studies are needed to elucidate the underlying pathophysiology.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"1976122"},"PeriodicalIF":0.6,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12055323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Takotsubo Cardiomyopathy Triggered by MRI-Induced Fear and Anxiety.","authors":"Ahmed Hassaan Qavi, Andreea Constanta Stan, Ateet Kosaraju, Rony L Shammas","doi":"10.1155/cric/2612009","DOIUrl":"https://doi.org/10.1155/cric/2612009","url":null,"abstract":"<p><p>Takotsubo cardiomyopathy (TC), or 'broken heart syndrome,' is marked by transient left ventricular dysfunction in the absence of acute, severe coronary artery disease that explains the pattern and degree of LV dysfunction. Both emotional and physical stressors have been associated with TC. We present a case of TC that was precipitated by a routine magnetic imaging resonance scan, highlighting a rare and previously unreported trigger for TC.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"2612009"},"PeriodicalIF":0.6,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Repeat AngioVac Debulking of a Large Right Atrial Thrombus With Extension From the Hepatic Vein.","authors":"Leonard Palatnic, Tim Avino, Edward J Spangenthal, David M Zlotnick","doi":"10.1155/cric/9155374","DOIUrl":"https://doi.org/10.1155/cric/9155374","url":null,"abstract":"<p><p>The AngioVac mechanical aspiration system has emerged in the literature as a viable treatment option for patients with intracardiac masses and thrombi and who are deemed high risk for cardiac surgery. Notably, it has been shown to be an effective treatment modality for the debulking of thrombi in the setting of malignancy. We present a case of repeat AngioVac debulking of a large right atrial thrombus with extension from the hepatic vein in the setting of advanced malignancy complicated by <i>Enterococcus faecium</i> endocarditis.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"9155374"},"PeriodicalIF":0.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12041637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Less Is More: Management of Left Atrial Appendage Perforation With Impending Cardiac Tamponade Following Watchman Device Placement.","authors":"Syeda Beenish Bareeqa, Ahmad Nawa, Arooge Towheed, Juwairiya Shuroog, Karthik Ramireddy, Shahabuddin Soherwardi","doi":"10.1155/cric/2574323","DOIUrl":"https://doi.org/10.1155/cric/2574323","url":null,"abstract":"<p><p>By 2030, the United States will have over 12 million people with atrial fibrillation, which carries a five-fold increase in risk of stroke. Watchman device is an alternative in patients who are poor candidates for anticoagulation. Here, we present a rare case of Watchman device implantation related to left atrial appendage (LAA) perforation noted intraoperatively with portion of the device in the pericardial space. A 93-year-old female with high fall risk and on Coumadin presented for Watchman device placement. During implantation, LAA perforation was noted with exudation of contract in the pericardium during deployment, and decision to deploy the device was made, hoping it would help seal the leak. Retrieving the device was thought to put the patient at risk of bigger perforation. Following which successful pericardial window with temporary drain placement avoided sternotomy and overall had a good outcome. A Watchman device with self-expanding frame covering the left atrial facing surface was deployed, after which a rare but potential complication of perforation was noted during delivery. The device left in place sealed the leak and prevented potential worsening incase device was retrieved. Eventually, this decision improved the outcome of the patient.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"2574323"},"PeriodicalIF":0.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12008479/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined Minimally Invasive Surgical and Percutaneous Approaches for a Patient on Hemodialysis With Severe Aortic Stenosis and Complex Coronary Artery Disease.","authors":"Teruaki Wada, Kentaro Honda, Hironori Kitabata, Yoshiharu Nishimura, Atsushi Tanaka","doi":"10.1155/cric/9229849","DOIUrl":"10.1155/cric/9229849","url":null,"abstract":"<p><p>Patients on hemodialysis with concomitant severe aortic stenosis (AS) and multivessel coronary artery disease (CAD) are at high risk for surgical aortic valve replacement (SAVR) and coronary artery bypass grafting (CABG). Transsubclavian-transcatheter aortic valve implantation (TSc-TAVI) is a well-established alternative approach to transfemoral TAVI for patients with unfavorable femoral access. Herein, we report a case in which minimally invasive surgical treatment and TSc-TAVI were performed simultaneously in a patient with severe AS and multivessel CAD undergoing hemodialysis. An 85-year-old man undergoing hemodialysis for end-stage renal disease owing to severe AS (mean pressure gradient, 46 mmHg; aortic valve area, 0.75 cm²; and left ventricular ejection fraction, 59%) presented to our hospital with chest pain on exertion. Preoperative coronary angiography revealed significant stenosis of the left anterior descending (LAD) coronary artery and right coronary artery (RCA), requiring revascularization. However, the patient was not a good candidate for transfemoral TAVI because of a porcelain ascending aorta and a shaggy descending aorta observed on computed tomography. He was scheduled for concomitant right TSc-TAVI and minimally invasive cardiac surgery (MICS)-CABG after percutaneous coronary intervention (PCI) for the RCA. The treatment was successful. Simultaneous TSc-TAVI and MICS-CABG with PCI may be applied as a minimally invasive surgical treatment modality for patients with AS and CAD undergoing hemodialysis.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"9229849"},"PeriodicalIF":0.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11952915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143755844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fulminant Cardiac Sarcoidosis Successfully Treated With Aggressive Immunosuppressive Therapy.","authors":"Kaori Yasumura, Fusako Sera, Yasuhiro Akazawa, Kei Nakamoto, Makiko Kawai, Masako Kurashige, Daisuke Nakamura, Takafumi Oka, Isamu Mizote, Eiichi Morii, Tomohito Ohtani, Yasushi Sakata","doi":"10.1155/cric/1350557","DOIUrl":"https://doi.org/10.1155/cric/1350557","url":null,"abstract":"<p><p><b>Background:</b> The clinical course of cardiac sarcoidosis is typically subacute, and fulminant cases requiring mechanical circulatory support are rare. Here, we report the case of a patient with pathologically diagnosed cardiac sarcoidosis who presented with fulminant myocarditis and whose cardiac function was improved by aggressive immunosuppressive therapy based on the treatment of giant cell myocarditis. <b>Case Presentation:</b> A 55-year-old woman presented with progressive dyspnoea and nausea that persisted for 1 month and was eventually diagnosed with acute heart failure. Echocardiography showed a reduced left ventricular ejection fraction with thinning of the basal septal wall. During hospitalisation, she experienced ventricular tachycardia and fibrillation attacks, and bradycardia due to a complete atrioventricular block and sinus dysfunction was observed after starting amiodarone. Subsequently, she underwent intra-aortic balloon pump insertion in addition to inotropic agent administration; however, venoarterial extracorporeal membrane oxygenation and Impella 5.0 were needed because biventricular dysfunction progressed. We diagnosed our patient with cardiac sarcoidosis based on the pathological findings revealing inflammatory cell infiltration, including giant cells with extensive fibrosis and granulomas. However, the possibility of giant cell myocarditis could not be ruled out because of the fulminant clinical course; therefore, aggressive immunosuppressive therapy with corticosteroids and cyclosporine was started. Her cardiac function improved, and all mechanical circulatory support and inotropic agents were discontinued. <b>Conclusion:</b> Cardiac sarcoidosis is difficult to differentiate from giant cell myocarditis because they have many similarities in terms of myocardial histopathology and clinical manifestations. While whether the two diagnoses are parts of a single-disease continuum remains debatable, aggressive combination immunosuppressive therapy may contribute to favourable outcomes.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"1350557"},"PeriodicalIF":0.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11986919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hydralazine-Induced ANCA Vasculitis Presenting With Pericarditis: A Novel Case and Literature Review.","authors":"Ahmed Sami Hammami, Osejie Oriaifo, Sinda Hidri, Sukhvir Singh, Husam El Sharu, Joshua Peltz, Soroush Nomigolzar, Kunjan Udani","doi":"10.1155/cric/9932632","DOIUrl":"https://doi.org/10.1155/cric/9932632","url":null,"abstract":"<p><p>Hydralazine, a commonly used arterial vasodilator for managing congestive heart failure and hypertension, is known to be associated with drug-induced lupus and, less frequently, antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Drug-induced AAV typically carries a favorable long-term prognosis and is not commonly linked to cardiovascular or ocular involvement. Pericarditis cases associated with hydralazine have not been previously reported. We present a rare case involving an 85-year-old woman on long-term hydralazine therapy, initially presenting with acute lobar pneumonia. During her hospitalization, she developed pericarditis, chemosis, and conjunctivitis in her eyes, along with cutaneous lesions described as a maculopapular rash on her face, tender bullae on her digits, and a petechial rash on her back. Laboratory findings were consistent with drug-induced AAV, showing positive myeloperoxidase and proteinase 3 antibodies. An attempted diagnostic pericardiocentesis was unsuccessful. Hydralazine was discontinued, and she was successfully treated with corticosteroids and tolerated immunosuppression well. Subsequently, she recovered and was discharged from the hospital.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"9932632"},"PeriodicalIF":0.6,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11986942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ivabradine for Incessant Atrial Tachycardia in a 1-Year-Old Child After Tetralogy of Fallot Repair.","authors":"Haikal Balweel, Rubiana Sukardi, Eva Miranda Marwali, Rifqi Rizkani Eri, Novaro Adeneur Tafriend, Agus Harsoyo","doi":"10.1155/cric/2601345","DOIUrl":"10.1155/cric/2601345","url":null,"abstract":"<p><p><b>Background</b>: Ivabradine is a novel drug with the ability to reduce heart rate without compromising myocardial contractility or blood pressure. Studies on this drug exist mainly for heart failure and coronary artery disease; for arrhythmia, the studies are limited to small sample trials and case series, mostly unrandomized. Additionally, its evidence for arrhythmia in pediatric patients is limited. Here, we present a case of successful ivabradine administration for incessant atrial tachycardia in a 1-year-old child following tetralogy of Fallot (TOF) repair. <b>Case</b>: A 1-year-old child experienced incessant tachyarrhythmia episodes after TOF repair. Multiple standard therapies, including adenosine, amiodarone, multiple cardioversions, beta-blockers, and digoxin, failed to convert the rhythm. Considering the limited therapy options and existing case reports, ivabradine was administered at a dose of 0.1 mg/kg. Subsequently, sinus rhythm was restored 8 h after its administration, with the heart rate significantly decreased, and the patient returned to a stable hemodynamic status. <b>Discussion</b>: Ivabradine may be an option for incessant atrial tachycardia in pediatric patients. Although most tachyarrhythmias following TOF repair occur due to a reentry mechanism, focal mechanisms can also occur, suggested by timing, gradual acceleration after cardioversion and its response to ivabradine. Future studies are needed to further understand the safety and efficacy of ivabradine for atrial tachycardia in pediatric patients.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"2601345"},"PeriodicalIF":0.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11832250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Endovascular Technique for Thrombus Removal: The \"Super Grab a Clot and Hold ON (Super GACHON)\" Technique.","authors":"Takahiro Tokuda, Hideyuki Takimura, Yasuhiro Oba, Keisuke Hirano","doi":"10.1155/cric/5525113","DOIUrl":"https://doi.org/10.1155/cric/5525113","url":null,"abstract":"<p><p>We present a case of a 60-year-old man with claudication in his right foot; the patient had received stent-graft implantation for the right superficial femoral artery (SFA) 1 year ago. Computed tomography angiography suggested stent occlusion of the right SFA, and a thrombus was considered to cause occlusion. To avoid distal embolization, we performed lesion recanalization via a trans-ankle intervention. First, we performed aspiration for the lesion; however, the thrombus persisted. Second, we performed the \"Super Grab a Clot and Hold ON\" technique and removed several thrombi. Finally, we used drug-coated balloons as a final device for the lesion. Two years later, the right SFA was found open upon an ultrasonography.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"5525113"},"PeriodicalIF":0.6,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143016183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}