Nicholas P Kondoleon, Andres Palomo, Justin Armstrong, Elvis Cami, Ivan D Hanson
{"title":"Percutaneous Closure of a Ruptured Sinus of Valsalva Aneurysm to Right Atrium Fistula.","authors":"Nicholas P Kondoleon, Andres Palomo, Justin Armstrong, Elvis Cami, Ivan D Hanson","doi":"10.1155/cric/6634261","DOIUrl":"10.1155/cric/6634261","url":null,"abstract":"<p><p>Ruptured sinus of Valsalva aneurysm is a life-threatening problem that usually requires emergent surgical management. This case illustrates a transcatheter repair of a ruptured sinus of Valsalva aneurysm creating a fistula to the right atrium in a patient who was not a candidate for surgery.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"6634261"},"PeriodicalIF":0.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490912/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Omar Hassan, Can Baba Arın, Said Abdirahman Ahmed, Ishak Ahmed Abdi, Ahmed Shafie Aden, Mohamed Osman Omar Jeele, Ahmed Elmi Abdi
{"title":"<i>Candida</i>-Induced Infective Endocarditis With Large Vegetation on a Bicuspid Aortic Valve in an Immunocompetent Patient.","authors":"Mohamed Omar Hassan, Can Baba Arın, Said Abdirahman Ahmed, Ishak Ahmed Abdi, Ahmed Shafie Aden, Mohamed Osman Omar Jeele, Ahmed Elmi Abdi","doi":"10.1155/cric/1447191","DOIUrl":"10.1155/cric/1447191","url":null,"abstract":"<p><p><b>Introduction:</b> Infective endocarditis (IE) is a life-threatening condition caused by microbial infection of the heart valves or endocardium. Fungal IE, predominantly caused by the <i>Candida</i> species, accounts for less than 2% of IE cases, and is usually associated with immunosuppression or other risk factors. This case report describes an unusual instance of <i>Candida albicans</i> endocarditis with extensive aortic valve vegetation in an immunocompetent patient, highlighting the challenges in diagnosis and management. <b>Case Report:</b> A 26-year-old active-duty soldier with no history of chronic illness presented with dyspnea, peripheral edema, and oliguria. Examination revealed a diastolic murmur, anemia, acute renal failure, and elevated inflammatory markers. Imaging showed cardiomegaly, pleural effusion, and a bicuspid aortic valve with large, mobile vegetations. Blood cultures confirmed <i>C. albicans</i>, and antifungal therapy with fluconazole was initiated. Despite aggressive medical management, including hemodialysis, the patient's condition deteriorated, and due to hemodynamic instability, surgery was not feasible. The patient unfortunately succumbed to complications. <b>Discussion:</b> <i>Candida</i> endocarditis is uncommon in immunocompetent individuals; biofilms enhance resistance against antifungal therapy and the immune response, even in immunocompetent individuals. The absence of conventional risk factors poses diagnostic challenges. The case also underscores the rapid progression and poor prognosis of fungal IE, particularly with extensive vegetations and hemodynamic instability. <b>Conclusion:</b> <i>Candida</i> endocarditis is a rare but severe condition, even in healthy individuals. This case emphasizes the importance of early recognition, comprehensive management, and further research to optimize outcomes in fungal IE.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"1447191"},"PeriodicalIF":0.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12490918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Priya Ramcharan, Nicholas Pereira, Matthew Maharaj, Arun Katwaroo, Valmiki Seecheran, Rajeev Seecheran, Dayna Lalchansingh, Naveen Seecheran
{"title":"Suspected Energy Drink-Induced Acute Coronary Syndrome With Sudden Cardiac Arrest.","authors":"Priya Ramcharan, Nicholas Pereira, Matthew Maharaj, Arun Katwaroo, Valmiki Seecheran, Rajeev Seecheran, Dayna Lalchansingh, Naveen Seecheran","doi":"10.1155/cric/1202116","DOIUrl":"10.1155/cric/1202116","url":null,"abstract":"<p><p>Overconsumption of energy drinks containing high levels of caffeine has been increasingly linked to cardiovascular morbidity and mortality. This case report describes a 24-year-old Caribbean-Black male with no prior comorbidities who experienced an aborted sudden cardiac death (SCD) after a recent energy drink binge a few hours prior to his ventricular fibrillation (VF) cardiac arrest. Primary percutaneous coronary intervention (PPCI) was successfully performed for a dreaded widowmaker lesion, thought to have arisen as a sequela of his excessive energy drink intake. The clinician should be cognizant of the major adverse cardiovascular events (MACEs), such as acute coronary syndromes (ACSs) and lethal arrhythmias, implicated with energy drink consumption.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"1202116"},"PeriodicalIF":0.5,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413948/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria V Manrique-Marquez, Jorge P Juarez-Lloclla, Christian A Rodríguez-Saldaña, Franco León-Jiménez
{"title":"Brugada Phenocopy Associated With Toxic Myocarditis due to Aluminum Phosphide: A Case Report.","authors":"Maria V Manrique-Marquez, Jorge P Juarez-Lloclla, Christian A Rodríguez-Saldaña, Franco León-Jiménez","doi":"10.1155/cric/8858716","DOIUrl":"10.1155/cric/8858716","url":null,"abstract":"<p><p>We present the case of a 27-year-old woman who ingested aluminum phosphide (AlP) in a suicide attempt, leading to severe toxic myocarditis and a transient Brugada pattern (Brugada phenocopy [BrP]) on her electrocardiogram (ECG). The initial treatment included supportive measures and management of a non-ST elevation acute coronary syndrome. Despite the severity of her condition, the patient stabilized, with normalization of ECG findings and improvement in left ventricular function. This case highlights the importance of recognizing BrP as a potential manifestation of toxic myocarditis, especially in the context of AlP poisoning, and underscores the critical need for early intervention and appropriate management.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"8858716"},"PeriodicalIF":0.5,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12396896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Papillary Muscle Rupture During Percutaneous Transvenous Mitral Commissurotomy: An Uncommon Scenario Exempt From Emergency Surgical Conversion.","authors":"Hiroki Okamoto, Atsushi Hayashi, Kohei Asada, Misato Kodama, Yousuke Higo, Noriaki Yagi, Yoshihisa Nakagawa","doi":"10.1155/cric/5005780","DOIUrl":"10.1155/cric/5005780","url":null,"abstract":"<p><p>Papillary muscle rupture is a rare but serious complication during percutaneous transvenous mitral commissurotomy (PTMC). In many cases, it leads to acute significant mitral regurgitation (MR), requiring urgent surgical repair. We performed PTMC for a 49-year-old woman with symptomatic moderate rheumatic mitral stenosis. Initial balloon inflation resulted in papillary muscle rupture; however, it did not induce leaflet prolapse and worsening of MR. Finally, we succeeded in achieving a mean pressure gradient of less than 5 mmHg without worsening of MR through several balloon inflations. We experienced a rare case where papillary muscle rupture occurred during PTMC, but there was no development of acute significant MR, and salvage surgery was not required.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"5005780"},"PeriodicalIF":0.5,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393946/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nihar Jena, Izza Saeed, Mackenzie Hamilton, Christian Tocquica, Sreekant Avula, Ramiz Sayyed, Juan Bastidas, Mark Studeny
{"title":"Pneumococcal Pyopericardium With Xiphoid Osteomyelitis in HIV/AIDS: A Rare but Potentially Fatal Complication.","authors":"Nihar Jena, Izza Saeed, Mackenzie Hamilton, Christian Tocquica, Sreekant Avula, Ramiz Sayyed, Juan Bastidas, Mark Studeny","doi":"10.1155/cric/5008190","DOIUrl":"10.1155/cric/5008190","url":null,"abstract":"<p><p><b>Background:</b> Purulent pericarditis is a rare, life-threatening condition that has become exceedingly uncommon due to widespread use of antibiotics. However, immunocompromised patients remain susceptible to such opportunistic infections. It is typically caused by direct extension or hematogenous spread from a secondary bacterial source. <b>Case Description:</b> We report a 55-year-old man with HIV cardiomyopathy who was transferred from an outside facility for chest pain and dyspnea, with an electrocardiogram suggestive of an ST-segment elevation myocardial infarction, prompting emergent cardiac catheterization, which revealed normal coronary arteries. A bedside echocardiogram revealed a large pericardial effusion with tamponade physiology, leading to pericardiocentesis. The pericardial fluid analysis revealed a high white blood cell count and a significantly elevated lactate dehydrogenase level, and cultures were positive for <i>Streptococcus pneumoniae</i>. Despite receiving antibiotics, the effusion reaccumulated, necessitating a subxiphoid pericardial wash and drainage. The xiphoid biopsy was consistent with acute osteomyelitis. The patient was discharged with long-term antibiotics and scheduled outpatient follow-ups. <b>Conclusion:</b> This case illustrates an unusual presentation of HIV-AIDS, highlighting advancements in managing pneumococcal pyopericardium with tamponade and the ongoing risk of opportunistic infections despite antiretroviral treatment. Though rare, pyopericardium can be fatal; so prompt diagnosis and multidisciplinary management are essential to improve outcomes.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"5008190"},"PeriodicalIF":0.5,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12367396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144978116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anne Sandstrom, Kristen Errico, Debanshu Roy, Andrea J Carpenter, Anand Prasad
{"title":"Successful Impella 5.0 Catheter Removal in the Setting of Left Ventricular Thrombus With Use of the Sentinel Cerebral Protection Device.","authors":"Anne Sandstrom, Kristen Errico, Debanshu Roy, Andrea J Carpenter, Anand Prasad","doi":"10.1155/cric/3481920","DOIUrl":"10.1155/cric/3481920","url":null,"abstract":"<p><p>Mechanical circulatory support devices, such as the Impella catheter (Abiomed, Danvers, Massachusetts), continue to become more commonplace in patients undergoing high-risk percutaneous coronary intervention (PCI) or those in cardiogenic shock. Thrombus in the left ventricle is a contraindication to Impella placement. Here, we present a patient with an anterior ST elevation myocardial infarction who underwent primary PCI with subsequent development of cardiogenic shock followed by Impella placement, who then later developed an LV thrombus. The Impella was removed after placement of a Sentinel cerebral protection device (Boston Scientific, Massachusetts). The left carotid filter of the Sentinel captured a thrombus fragment. The patient did not have any neurological compromise. This case represents the first report of actual capture of LV thrombus by a Sentinel system in this context. The case suggests the potential value of the Sentinel cerebral protection device to lower the risk of an embolic event during Impella removal in selective clinical scenarios.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"3481920"},"PeriodicalIF":0.6,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144310802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuel Mallol-Simmonds, Rocio Fuentes-Garrido, Alfredo Villarroel, Catalina Valenzuela, Marcelo Llancaqueo
{"title":"Severe Conduction Disturbances Accompanying Anterior Wall Myocardial Infarction: An Infrequent Presentation to Remember.","authors":"Manuel Mallol-Simmonds, Rocio Fuentes-Garrido, Alfredo Villarroel, Catalina Valenzuela, Marcelo Llancaqueo","doi":"10.1155/cric/8331292","DOIUrl":"10.1155/cric/8331292","url":null,"abstract":"<p><p><b>Background:</b> Anterior ST-elevation myocardial infarction (STEMI) is frequently associated with severe complications, such as myocardial dysfunction and conduction abnormalities. Complete atrioventricular block (CAVB), especially when combined with bifascicular block, is a rare but critical presentation that reflects extensive myocardial damage, often linked to proximal left anterior descending (LAD) artery occlusion. <b>Case Presentation:</b> A 76-year-old male with a history of hypertension, diabetes mellitus, and dyslipidemia presented to the emergency department with a 6-day history of gastrointestinal symptoms and recurrent syncope. On arrival, he exhibited bradycardia, hypotension, and mottling, progressing to cardiac arrest. The return of spontaneous circulation was achieved after one cycle of advanced cardiovascular life support. Electrocardiography revealed CAVB with a ventricular escape rhythm displaying right bundle branch block morphology, left anterior fascicular block, and anterior ST-segment elevation. Emergency interventions included endotracheal intubation, Swan-Ganz catheterization, transvenous pacing, and vasopressor support. Echocardiography demonstrated severe left ventricular systolic dysfunction with an ejection fraction of 25%. Coronary angiography identified critical proximal stenoses in the LAD and circumflex arteries, managed with percutaneous coronary intervention and stent placement. Persistent conduction abnormalities and systolic dysfunction necessitated implantation of a cardiac resynchronization therapy defibrillator (CRT-D). Despite extensive rehabilitation efforts, the patient died after 60 days of hospitalization. <b>Discussion:</b> This case highlights the importance of rapid recognition and intervention in anterior STEMI complicated by CAVB and bifascicular block, signaling significant proximal LAD involvement. Advanced therapeutic options, including CRT-D, are crucial for addressing these rare, life-threatening conduction disturbances. The fatal outcome underscores the need for vigilant follow-up and individualized preventive strategies to improve prognosis in such complex STEMI cases.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"8331292"},"PeriodicalIF":0.6,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12126253/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayman Helal, Mohsin Farooq, Mohamed Alama, Ibrahim Antoun
{"title":"Navigating the Uncommon: PCI to an Anomalous Right Coronary Artery With a Malignant Course Following Failed Arterial Grafts.","authors":"Ayman Helal, Mohsin Farooq, Mohamed Alama, Ibrahim Antoun","doi":"10.1155/cric/8125980","DOIUrl":"10.1155/cric/8125980","url":null,"abstract":"<p><p>A 67-year-old male presented with non-ST elevation myocardial infarction (NSTEMI) with underlying anomalous origin of the right coronary artery (RCA) and a malignant course between the aorta and pulmonary artery. Previous CABG with LIMA and RIMA grafts had failed, leaving the patient with severe in-stent restenosis (ISR) in the LAD and degenerated, blocked grafts. The patient underwent percutaneous coronary intervention (PCI) to the anomalous RCA, which posed challenges in engagement due to its anomalous course. This case report discusses the complexities of managing such anatomies, emphasizing the role of CT coronary angiography, the difficulty of engaging anomalous arteries, and the techniques used to achieve successful PCI.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"8125980"},"PeriodicalIF":0.6,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088839/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lessons From a Complex Case of Calcific Constrictive Pericarditis: A Case Report.","authors":"Varun Kasula, Vikram Padala, Jagroop Doad, Hassan Awais, Vinod Chaubey, Aditya Sood, Lauren Golden","doi":"10.1155/cric/5514172","DOIUrl":"10.1155/cric/5514172","url":null,"abstract":"<p><p>Despite advances in imaging and diagnostics, calcific constrictive pericarditis (CCP) remains a rare and challenging entity, often masquerading as other cardiopulmonary conditions, leading to delayed diagnosis. We present a 70-year-old male with a history of heart failure, atrial fibrillation (AF), cirrhosis, chronic obstructive pulmonary disease (COPD), and prior pleural effusion, who was admitted with acute hypoxic respiratory failure and AF with rapid ventricular response (RVR). Imaging revealed extensive pericardial calcifications, leading to a diagnosis of CCP. The patient's clinical course was marked by refractory hypotension, altered mental status, and progressive cardiohepatic syndrome. Given his high surgical risk, he was managed conservatively and transitioned to palliative care. This case underscores the diagnostic and therapeutic challenges of CCP, particularly in patients with complex comorbidities where surgical intervention is not feasible. It highlights the need for early recognition and individualized management strategies to optimize outcomes in this challenging subset of patients.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2025 ","pages":"5514172"},"PeriodicalIF":0.6,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}