{"title":"A Case of Recurrent Syncope Solely Associated With Air Travel.","authors":"Varun Srivatsav, Brendon Macknak","doi":"10.1155/cric/3379568","DOIUrl":"https://doi.org/10.1155/cric/3379568","url":null,"abstract":"<p><p>A 68-year-old patient was referred for recurrent episodes of syncope associated solely with air travel. He did not experience episodes of syncope in other situations and was well otherwise. His ECG, echocardiogram, exercise stress test and MIBI were unremarkable. It was determined that the patient had been experiencing repeated vasovagal syncope from an uncommon trigger of air travel. He responded to nonpharmacological measures to treat vasovagal syncope and doses of fludrocortisone the night before air travel, and was thereafter able to travel successfully.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"3379568"},"PeriodicalIF":0.5,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13147344/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147845981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hypertensive Emergency in the Context of SARS-CoV-2 Infection: Clinical Course and Management.","authors":"Gudisa Bereda","doi":"10.1155/cric/9408438","DOIUrl":"https://doi.org/10.1155/cric/9408438","url":null,"abstract":"<p><p>Coronavirus Disease2019 (COVID-19) can increase sympathetic nervous system activity by inducing systemic inflammation and a cytokine storm. This can result in elevated blood pressure, increased heart rate, and vasoconstriction. A 67-year-old Black male was admitted to the emergency department with a chief complaint of shortness of breath for 2 days. On examination, he exhibited edema and symmetric palpable pulses in his lower limbs. His electrocardiogram revealed left axis deviation, sinus tachycardia, and ST-segment elevation. Reverse transcription-polymerase chain reaction confirmed COVID-19. Hydralazine (5 mg) was administered intravenously immediately. The patient was re-evaluated after 20 min during his stay in the emergency department. After two 5 mg doses of hydralazine, he developed reflex tachycardia. To control heart rate, IV hydralazine was replaced with oral atenolol (50 mg once daily), a <i>β</i>₁-blocker that reduces cardiac output. Subcutaneous enoxaparin 80 mg daily was given to prevent thrombotic complications in hospitalized COVID-19 patients. Acute hypertension and COVID-19-induced hypertensive emergencies in patients with preexisting hypertension are typically associated with a worse prognosis.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"9408438"},"PeriodicalIF":0.5,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13147342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147846014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shariq Hamid, Rory Bennet, Jessica Yao, Joshua Wong
{"title":"Cardiac Tamponade-A Rare Manifestation of Ruxolitinib Discontinuation Syndrome: A Case Report.","authors":"Shariq Hamid, Rory Bennet, Jessica Yao, Joshua Wong","doi":"10.1155/cric/8854255","DOIUrl":"https://doi.org/10.1155/cric/8854255","url":null,"abstract":"<p><p>A 52-year-old gentleman presenting with tachycardia was found to have a large pericardial effusion and cardiac tamponade. This case was on a background of long-standing myelofibrosis managed with ruxolitinib, which was recently withheld for an orthopaedic procedure. He was diagnosed with presumed ruxolitinib discontinuation syndrome (RDS), resulting in a large pericardial effusion due to an increased inflammatory response. He was managed with a pericardial window and prompt recommencement of ruxolitinib and steroids. This case highlights the importance and increasing prevalence of RDS with the serious consequence of cardiac tamponade. Symptoms of RDS should be recognised and managed with recommencement of a JAK inhibitor and steroids.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"8854255"},"PeriodicalIF":0.5,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13137292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147845999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehmet Ası Oktan, Hüseyin Dursun, Yelda Deligöz Bildacı, Berfu Korucu, Cihan Heybeli, Caner Çavdar, Serpil Müge Değer
{"title":"Bosutinib-Associated Cardiac Tamponade: Late-Onset Treatment-Emergent Adverse Event-A Case Report.","authors":"Mehmet Ası Oktan, Hüseyin Dursun, Yelda Deligöz Bildacı, Berfu Korucu, Cihan Heybeli, Caner Çavdar, Serpil Müge Değer","doi":"10.1155/cric/6696107","DOIUrl":"https://doi.org/10.1155/cric/6696107","url":null,"abstract":"<p><p>Fluid retention due to tyrosine kinase inhibitor administration might lead to pericardial effusion and right heart failure. Here, we present the case of a 63-year-old man with subacute cardiac tamponade complicated with heart failure, acute kidney injury, and generalized edema due to the bosutinib treatment.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"6696107"},"PeriodicalIF":0.5,"publicationDate":"2026-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13136675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147845954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shailendra Upadhyay, Whitney Fairchild, Olga T Salazar
{"title":"Are We Always Prepared for Urgent Coronary Interventions in Complex Adult Congenital Heart Disease Patients?","authors":"Shailendra Upadhyay, Whitney Fairchild, Olga T Salazar","doi":"10.1155/cric/5534523","DOIUrl":"https://doi.org/10.1155/cric/5534523","url":null,"abstract":"<p><p>The adult congenital heart disease population is on the rise, and coronary artery angiography may be required for evaluation of epicardial coronary arteries in these patients. A patient with complex congenital heart disease, including the Taussig-Bing anomaly, repaired with the Rastelli operation, developed iatrogenic right coronary artery dissection during selective angiography. This was successfully managed in a challenging procedure involving extensive stenting of the right coronary artery with a good outcome.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"5534523"},"PeriodicalIF":0.5,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147823607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of STEMI in an Ectatic and Tortuous Right Coronary Artery Using a Flexible Guide Catheter Extension: A Case Report.","authors":"Yasuyuki Toyama, Shinya Okabe, Tetsuya Hashimoto","doi":"10.1155/cric/5644505","DOIUrl":"https://doi.org/10.1155/cric/5644505","url":null,"abstract":"<p><strong>Background and aims: </strong>Coronary artery ectasia poses unique challenges during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction (STEMI), owing to thrombus burden and vascular tortuosity. This case demonstrates successful reperfusion using a flexible, hydrophilic-coated guide catheter extension (GuidePlus, Nipro, Osaka, Japan).</p><p><strong>Methods: </strong>A 45-year-old man with inferior STEMI had complete occlusion of a severely ectatic (6.5 mm, 1.8× reference) and tortuous RCA with a 'shepherd's crook' morphology. The conventional GuideLiner failed to cross. GuidePlus, a soft and hydrophilic extension, enabled thrombus aspiration and intracoronary urokinase (240,000 IU) delivery. A 4.0 × 28-mm drug-eluting stent (Ultimaster, Terumo) was deployed and postdilated (5.0-mm NC balloon).</p><p><strong>Results: </strong>The GuidePlus enabled smooth navigation, direct aspiration and thrombolysis. Final angiography confirmed TIMI Grade 3 flow with minimal residual thrombus. The patient was discharged uneventfully and has remained event-free with dual antiplatelet therapy (aspirin and prasugrel).</p><p><strong>Conclusion: </strong>GuidePlus offers excellent flexibility and crossability for managing STEMI in ectatic and tortuous arteries when conventional devices fail.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"5644505"},"PeriodicalIF":0.5,"publicationDate":"2026-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13090674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikitha Murthy, Brian Diep, Jonathan Evans, Dmitry Abramov, Diane Tran
{"title":"Mavacamten as an Effective Treatment for HCM With Latent Exercise-Induced Obstruction: A Case Report.","authors":"Nikitha Murthy, Brian Diep, Jonathan Evans, Dmitry Abramov, Diane Tran","doi":"10.1155/cric/9385301","DOIUrl":"https://doi.org/10.1155/cric/9385301","url":null,"abstract":"<p><strong>Background: </strong>Hypertrophic cardiomyopathy (HCM) is a myocardial disorder characterized by hypertrophy of the left ventricle that can lead to significant symptoms, particularly with exercise. For patients with HCM who demonstrate obstructive physiology, the first-in-class targeted cardiac specific myosin inhibitor, mavacamten, has been found to reduce the degree of obstruction as well as symptoms.</p><p><strong>Case summary: </strong>We present a patient with symptomatic HCM who had no left ventricular outflow tract obstruction (LVOTO) at rest but demonstrated obstruction on treadmill stress echocardiography. She had symptomatic improvement after treatment with mavacamten.</p><p><strong>Discussion: </strong>Patients with symptomatic HCM who do not demonstrate elevated resting gradients may benefit from evaluation of exercise-induced gradients to diagnose obstructive HCM and guide initiation of targeted therapy with mavacamten.</p><p><strong>Take home message: </strong>Mavacamten may be safe and effective in patients who demonstrate LVOTO only upon provocation with exercise.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"9385301"},"PeriodicalIF":0.5,"publicationDate":"2026-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13088151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo Sanhueza, Matthew Hanson, Victor Neira, Sanoj Chacko, Andres Enriquez, Roji Oli, Mariana Saramago, Cengiz Burak
{"title":"Zero-Fluoroscopy Radiofrequency Ablation of a Right Ventricular Outflow Tract PVC in a Patient With Situs Inversus Totalis: When Precision Matters.","authors":"Eduardo Sanhueza, Matthew Hanson, Victor Neira, Sanoj Chacko, Andres Enriquez, Roji Oli, Mariana Saramago, Cengiz Burak","doi":"10.1155/cric/1241820","DOIUrl":"https://doi.org/10.1155/cric/1241820","url":null,"abstract":"<p><strong>Background: </strong>Congenital cardiac anomalies present unique challenges for adult cardiac electrophysiologists, particularly when attempting complex ablation procedures.</p><p><strong>Case summary: </strong>We report the case of a 60-year-old male with situs inversus totalis who presented with symptomatic, high-burden premature ventricular complexes (PVCs) refractory to medical therapy. Using reversed (mirror-image) precordial lead placement, high-definition 3D electroanatomic mapping, and intracardiac echocardiography, successful radiofrequency ablation was achieved using a completely zero-fluoroscopy approach.</p><p><strong>Discussion: </strong>In patients with congenital cardiac anomalies, the applicability of zero-fluoroscopy strategies is often limited because of their complex anatomy. Successful management requires in-depth anatomical understanding and carefully adapted procedural techniques. This case highlights that even in the setting of significant anatomical variation, a systematic zero-fluoroscopy approach can lead to effective and safe outcomes.</p><p><strong>Take‐home message: </strong>Zero-fluoroscopy PVC radiofrequency ablation using high-definition 3D mapping and intracardiac echocardiography is a feasible and safe approach, even in anatomically challenging cases such as situs inversus.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"1241820"},"PeriodicalIF":0.5,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13080684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147700855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unveiling the Invisible: Inferior STEMI With an Absent Right Coronary Artery Rescued by PCI to the Left Circumflex Artery.","authors":"Jehan Dad Khan, Omar Bajmmal, Ibrahim Antoun","doi":"10.1155/cric/8887458","DOIUrl":"https://doi.org/10.1155/cric/8887458","url":null,"abstract":"<p><p>Coronary artery anomalies, though uncommon, can pose significant diagnostic and therapeutic challenges, especially during acute coronary syndromes (ACS). We present a rare case of a 57-year-old male who presented with classical symptoms of inferior ST-segment elevation myocardial infarction (STEMI). Initial coronary angiography failed to identify the right coronary artery (RCA), eventually revealing an absent RCA ostium. The superdominant left circumflex artery (LCX) was found to be entirely occluded, supplying the territory typically serviced by the absent RCA. Successful primary percutaneous coronary intervention (PCI) was performed using a drug-eluting stent (DES), restoring TIMI-III flow and resolving symptoms promptly. Further imaging with contrast-enhanced computed tomography coronary angiography (CTCA) confirmed the congenital absence of the RCA, emphasising the critical role of advanced imaging in diagnosing coronary anomalies. Our case underscores the importance of considering rare congenital anomalies in acute cardiac presentations. It highlights the pivotal role of rapid recognition, targeted imaging and intervention in such anomalies to ensure optimal patient outcomes. It advocates a multidisciplinary approach, integrating cardiologists, radiologists and interventional specialists to enhance clinical decision-making and management effectiveness in similar complex scenarios.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"8887458"},"PeriodicalIF":0.5,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Case of Myocarditis in the Context of Norovirus Gastroenteritis.","authors":"Eva S Blake, Zachary T St Clair, Kent S Brummel","doi":"10.1155/cric/5867611","DOIUrl":"https://doi.org/10.1155/cric/5867611","url":null,"abstract":"<p><p>We present a rare case of viral myocarditis secondary to a rarely reported cause, norovirus. This case highlights the diagnostic challenges associated with acute chest pain accompanied by troponin elevation. We discuss the significance of advanced imaging techniques, particularly cardiac magnetic resonance, in the diagnosis of this condition.</p>","PeriodicalId":51760,"journal":{"name":"Case Reports in Cardiology","volume":"2026 ","pages":"5867611"},"PeriodicalIF":0.5,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147678420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}