Journal of Obstetrics and Gynecology of India最新文献

{"title":"Risk of Gynaecological Cancers as Second Primary in Non-gynaecological Cancer Survivors: A Retrospective Cohort Study.","authors":"N R Sindhu, Dhanya Susan Thomas, Ajit Sebastian, Anitha Thomas, Rachel Chandy, Sherin Daniel, Vinotha Thomas","doi":"10.1007/s13224-024-02041-0","DOIUrl":"10.1007/s13224-024-02041-0","url":null,"abstract":"<p><strong>Aims and objectives: </strong>This study aims to explore the clinical-pathological profile of gynaecological malignancies occurring as a second cancer and identify their modifiable and non-modifiable risk factors.</p><p><strong>Methodology: </strong>This retrospective cohort study included women operated for gynaecological carcinoma following a previous treated malignancy, in the gynaecologic oncology department of a tertiary care hospital, between 1st January 2016 and 31st December 2021. Demographic details, clinical and pathological characteristics of the current malignancy and previous malignancy were obtained from medical records and analysed using descriptive statistics.</p><p><strong>Results: </strong>During this period, 2370 women with gynaecological malignancies were operated, of whom 27 (1.1%) patients had gynaecological malignancy as a second malignancy. This included 19 (70.3%) endometrial and 8 (29.6%) ovarian cancer patients following a median period of 48 (24-144 months) from the index malignancy. Their median age and BMI were 60 years (37-67) and 27 (17-39.1), respectively. Endometrioid endometrial cancer was most common and was preceded by breast carcinoma in 19 (70.37%) and colorectal in 5 (18.5%). Four patients had previous microsatellite unstable colorectal cancer. Two patients were found to have mismatch repair deficient endometrial cancer on somatic testing. High-grade serous carcinoma was the most common ovarian histology and was preceded by breast cancer in 6 (75%). Four patients underwent germline testing, and one was found to have a (breast cancer gene) BRCA pathogenic mutation.</p><p><strong>Conclusion: </strong>Breast cancer and colon cancer can precede gynaecologic cancer. Individualization of somatic and genetic testing in colorectal and breast cancers will allow screening and prevention of second gynaecologic malignancies.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"75 Suppl 1","pages":"146-151"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Various Urogynaecological Lower Urinary Tract Symptoms (LUTS) in Relation to Mode of Delivery.","authors":"J B Sharma, Bhawna Arora, Rajesh Kumari, Nisha, Manasi Deoghare","doi":"10.1007/s13224-024-02044-x","DOIUrl":"10.1007/s13224-024-02044-x","url":null,"abstract":"<p><strong>Background: </strong>Urogynaecological problems are common in puerperium and are mainly related to mode of delivery being more common in vaginal delivery. It was a prospective study of over 300 puerperal women to see the prevalence of various urogynaecological problems in vaginal delivery (149 cases) vs caesarean section (151 cases).</p><p><strong>Methods: </strong>It is a prospective longitudinal observational study in which over 300 women underwent screening for urogynaecological problems in the first week postpartum. Women with urogynaecological symptoms were followed for 6 weeks for the persistence of symptoms, and those with moderate-to-severe symptoms were evaluated using urodynamic studies.</p><p><strong>Results: </strong>The two groups were similar in general characteristics, mean age (28.2 years vs. 26.9 years), parity (2.3 vs. 2.0), gestation (37.5 vs. 38.4 weeks) and socioeconomic status. Mean birth weight was also similar in two groups, group I with 2.62 ± 0.43 kg vs 2.75 ± 0.45 kg in group II (p value 0.35). Overall, 95 cases (31.6%) had urogynaecological symptoms in the first week postpartum and 22 cases (7.3%) had urogynaecological problems at 6 weeks postpartum with many patients showing more than one symptom. There were no significant differences in various urogynaecological symptoms in vaginal delivery (group I) and caesarean section (group II).</p><p><strong>Conclusion: </strong>The prevalence of various urogynaecological symptoms was seen in 31.6% in the first week and 7.3% at 6 weeks postpartum and didn't differ with mode of delivery.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"75 Suppl 1","pages":"159-165"},"PeriodicalIF":0.7,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085476/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bidding Adieu to a Golden Chapter…….","authors":"Madhuri Patel","doi":"10.1007/s13224-025-02102-y","DOIUrl":"https://doi.org/10.1007/s13224-025-02102-y","url":null,"abstract":"","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"75 1","pages":"12"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11903992/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating Complexities: Social, Ethical & Medicolegal Dilemmas of Hysterectomy in Young, Unmarried Women with Disabilities.","authors":"Jyotsna Yadav, Richa Sharma, Kiran Guleria, A G Radhika","doi":"10.1007/s13224-024-02043-y","DOIUrl":"https://doi.org/10.1007/s13224-024-02043-y","url":null,"abstract":"<p><strong>Purpose of study: </strong>The decision for hysterectomy in unmarried, young females, especially those with disabilities, is laden with many social, ethical and medicolegal dilemmas.</p><p><strong>Methods: </strong>In this case series, we present our challenges in the management of three disabled & unmarried girls who made a request for hysterectomy.</p><p><strong>Discussion and conclusion: </strong>Universal declaration of human rights, Constitution of India and the courts guarantee various rights to people with disabilities. However, there is a lack of comprehensive medicolegal framework to guide management in such cases especially in developing countries like India. This is an attempt to emphasise the need for specialised laws and medical board, for example '<i>Board for hysterectomy in special circumstances'</i> to help provide one-stop solutions to these women.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"75 1","pages":"89-91"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic Management of Pelvic Abcess Post Oocyte Retrieval.","authors":"S Krishnakumar, Shrutika O Makde","doi":"10.1007/s13224-024-02036-x","DOIUrl":"https://doi.org/10.1007/s13224-024-02036-x","url":null,"abstract":"","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"75 1","pages":"92-94"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11903975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Charged Up and Marching Ahead….","authors":"Sujata Dalvi","doi":"10.1007/s13224-025-02103-x","DOIUrl":"https://doi.org/10.1007/s13224-025-02103-x","url":null,"abstract":"","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"75 1","pages":"1-2"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"President's Address.","authors":"Sunita Tandulwadkar","doi":"10.1007/s13224-025-02098-5","DOIUrl":"https://doi.org/10.1007/s13224-025-02098-5","url":null,"abstract":"","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"75 1","pages":"3-11"},"PeriodicalIF":0.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11904042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143651931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age of Viability: Clarifying Prenatal Documentation and Definitions in India's Contemporary Medical Landscape.","authors":"Girija Wagh","doi":"10.1007/s13224-024-02096-z","DOIUrl":"https://doi.org/10.1007/s13224-024-02096-z","url":null,"abstract":"<p><p>The concept of foetal viability has evolved significantly and has been influenced by advancements in neonatal care and legal frameworks. This review explores the complexities of defining foetal viability in India's contemporary medical landscape, particularly in light of the recent extension of the Medical Termination of Pregnancy (MTP) Act to 24 weeks. The article examines the confusion surrounding the classification of extreme preterm births, Medical Termination of Pregnancy (MTP) Act, and prenatal documentation during sonography. It addresses the challenges in distinguishing between preterm birth and abortion and proposes solutions to standardize definitions and practices.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"74 6","pages":"484-488"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Trends in Medical Management of Endometriosis.","authors":"Madhuri Patel","doi":"10.1007/s13224-024-02097-y","DOIUrl":"https://doi.org/10.1007/s13224-024-02097-y","url":null,"abstract":"<p><p>Endometriosis affects about 10 percent women in the reproductive age group globally and approximately 42 million in India. Managing the patient's pain symptoms associated with endometriosis appears to be the cornerstone in endometriosis disease management. The ideal medical treatment in endometriosis would be suppressing estradiol enough to alleviate symptoms of endometriosis but maintain sufficient levels to mitigate hypoestrogenic side effects. NSAIDs are generally prescribed for the initial management of pain symptoms in endometriosis along with hormonal agents like progestogens or combined oral contraceptive pills (COCPs). Injectable depot gonadotropin-releasing hormone (GnRH) agonists such as leuprolide acetate and letrozole are effective as second-line agents in the management of endometriosis-associated pain. Dienogest is a 19-nortestosterone derivative which has a high specificity for progesterone receptors and improves endometriosis-related symptoms and the overall quality of life. Dydrogesterone is quite effective in the treatment of endometriosis-associated pelvic pain without causing suppression of ovulation. GnRH agonists and GnRH antagonists both have been used in the treatment of endometriosis. Elagolix a first oral, non-peptide gonadotropin-releasing antagonist for the management of moderate to severe pain associated with endometriosis is successfully used. Aromatase inhibitors are used as second-line drugs in the management of endometriosis-associated pelvic pain. They prevent the conversion of steroid precursors to estrogens, both at the periphery and at the ovarian level. Tamoxifen, raloxifene and bacidoxifen have an anti-proliferative effect and regress the endometriotic implants. Mifepristone (progesterone receptor antagonist) and Ulipristal acetate (SPRM) have been used for medical management of endometriosis. LNG-IUS is emerging as a good option for patients with endometriosis who are not desirous of conception. Hormonal management is one of the effective management options in endometriosis. One has to be mindful of molecule-specific adverse effects while prescribing drugs.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"74 6","pages":"479-483"},"PeriodicalIF":0.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11693626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Call For Action: The Obstetrician's Role In Peripartum Mental Health.","authors":"Anahita R Chauhan, Arnav R Chauhan","doi":"10.1007/s13224-024-02076-3","DOIUrl":"10.1007/s13224-024-02076-3","url":null,"abstract":"<p><p>Peripartum mental health is an underdiagnosed and undertreated entity; obstetricians are in a dilemma when patients present with signs of any mental disturbance. The peripartum period is fraught with triggers that can cause, or exacerbate, mental illness, and obstetricians need to be aware of diagnoses and treatment of blues, depression, psychosis and other problems. Key strategies that can be adopted are discussed in this review, along with the scenario in India.</p>","PeriodicalId":51563,"journal":{"name":"Journal of Obstetrics and Gynecology of India","volume":"74 5","pages":"386-390"},"PeriodicalIF":0.7,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11574220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}