Applied Neuropsychology-Adult最新文献

{"title":"Validity and reliability of modified box and block test and targeted box and block test in patients with stroke.","authors":"Lütfiye Akkurt, Cihan Caner Aksoy, Fatıma Yaman","doi":"10.1080/23279095.2025.2545543","DOIUrl":"https://doi.org/10.1080/23279095.2025.2545543","url":null,"abstract":"<p><strong>Introduction: </strong>The Box and Block Test (BBT) is commonly used to evaluate unilateral manual dexterity in patients with stroke. While the BBT is quick and simple to use, it causes large measurement variability because the administration is not standardized. In this study, we evaluated the validity and reliability of the modified BBT (mBBT) and a targeted BBT (tBBT) in patients with stroke.</p><p><strong>Method: </strong>Our participants were 50 patients with stroke. We evaluated the criterion validity of the mBBT and tBBT through its correlations with scores on the 9-Hole Peg Test (9-HPT), the Fugl-Meyer Assessment-Upper Extremity test (FMA-UE) and BBT. We analyzed the reliability with test-retest reliability.</p><p><strong>Results: </strong>The mBBT was strongly and positively correlated with the 9 HPT (<i>r</i> = 0.823), and strongly negatively correlated the BBT (<i>r</i> = -0.870) for the more-affected hand (<i>p</i> < 0.001). The tBBT was also strongly positively correlated with the 9 HPT (<i>r</i> = 0.913), and the BBT (<i>r</i> = -0.889) for the more-affected hand (<i>p</i> < 0.001). The mBBT was moderately positively correlated with the FMA-UE (<i>r</i> = -0.574), and the tBBT was moderately correlated with (<i>r</i> = -0.604) for the more-affected hand (<i>p</i> < 0.001). The ICCs for the mBBT and the tBBT ranged from 0.86 to 0.97 for the more-affected hand.</p><p><strong>Conclusion: </strong>In this sample, the mBBT and tBBT appeared to be valid and reliable for patients with stroke.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thrombolysis and visual neglect after right hemisphere infarct during a 6-month follow-up.","authors":"Laura Nurmi, Eija-Inkeri Ruuskanen, Mervi Jehkonen","doi":"10.1080/23279095.2025.2543072","DOIUrl":"https://doi.org/10.1080/23279095.2025.2543072","url":null,"abstract":"<p><p>We explored the association of thrombolysis with the occurrence of and recovery from visual neglect and associated symptoms, specifically initial ipsilateral orienting bias and slowed processing speed within six months after first-ever right hemisphere infarct. Sixty-two patients, matched for age, years of education and baseline stroke severity, were divided into two groups according whether receiving thrombolysis or not. Visual neglect was assessed with the Behavioral Inattention Test, ipsilateral orienting bias with starting point in cancelation tasks, and processing speed with cancelation time at the acute phase and six months post-stroke. At the acute phase, thrombolytic patients scored significantly better than non-thrombolytic patients with neglect measurements used. The groups did not differ according to starting points or cancelation times. At six months, the groups did not differ according to neglect measurements or starting points. However, thrombolytic patients were significantly faster than non-thrombolytic patients in performing the letter cancelation task. The results indicate association of thrombolysis with less visual neglect symptoms at the acute phase and faster visual search performance at six months. These results support preliminary indications of an association between thrombolysis and favorable short-term cognitive outcomes but also offer first indications of a long-term association between thrombolysis and beneficial cognitive outcome post-stroke.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic validity of the Persian version of Montreal Cognitive Assessment - basic for cognitive screening.","authors":"Ahmad R Khatoonabadi, Shirin Jafari, Amin Modarres Zadeh, Saman Maroufizadeh","doi":"10.1080/23279095.2025.2541812","DOIUrl":"https://doi.org/10.1080/23279095.2025.2541812","url":null,"abstract":"<p><strong>Background: </strong>The growing number of older people with Mild Cognitive Impairment (MCI) highlights the need for suitable and effective neuropsychological assessments. The Montreal Cognitive Assessment Basic (MoCA-B) is designed to identify MCI in individuals with lower literacy and education levels. This study seeks to validate the use of MoCA-B in the Persian-speaking population.</p><p><strong>Methods: </strong>In this cross-sectional study, the original English version of the MoCA-B test was translated into Persian using the forward-backward method. The study involved 60 cognitively healthy aging individuals, 30 with Alzheimer's disease, and 30 MCI patients. All participants met the MMSE, MoCA-B, DSM-5, and Albert's criteria.</p><p><strong>Results: </strong>MoCA-B scores in patients with AD were significantly lower than in the patients with MCI and healthy individuals (P < 0.001). They were significantly lower in MCI than individuals without cognitive impairment (P < 0.001). The cutoff score for discriminating between patients with AD/MCI and individuals without cognitive impairment was 20.5 (sensitivity = 95.0%, specificity = 88.3%, AUC = 0.972).</p><p><strong>Conclusion: </strong>This study shows that the MoCA-B is a suitable screening tool for distinguishing persons with cognitive impairment (MCI and AD) in the Persian-speaking population.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144805256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuropsychological assessment for epileptic disease: From theory to practice.","authors":"Lianlian Zhang, Xiaoli Pan, Qun Yu","doi":"10.1080/23279095.2025.2544821","DOIUrl":"https://doi.org/10.1080/23279095.2025.2544821","url":null,"abstract":"<p><strong>Background: </strong>Neuropsychological assessment plays a vital role in the clinical management of patients with epilepsy. It is widely used in the preoperative evaluation to determine the functional risks of epilepsy surgery, and also contributes to the diagnosis of cognitive and psychiatric comorbidities.</p><p><strong>Methods: </strong>We reviewed key domains of neuropsychological evaluation, including general intelligence, memory, cognitive and psychological functions, activities of daily living, social functioning, and the Wada test. Commonly used standardized scales and testing procedures were discussed in the context of their clinical relevance.</p><p><strong>Results: </strong>Neuropsychological assessment assists in diagnosing cognitive and behavioral comorbidities, evaluating treatment effects, guiding surgical decisions, and monitoring functional outcomes in epilepsy patients. Its findings are particularly valuable for localizing brain dysfunction, predicting postoperative outcomes, and informing multidisciplinary care strategies.</p><p><strong>Conclusions: </strong>Neuropsychological assessment is an indispensable component of epilepsy care, providing objective data to support individualized treatment. While limitations exist, ongoing refinement of assessment tools and training standards holds promise for broader clinical impact and integration into precision medicine frameworks.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subjective appraisal of cognition among American racial groups.","authors":"Bradley J Dixon, Allison C Moll, John L Woodard","doi":"10.1080/23279095.2025.2539173","DOIUrl":"https://doi.org/10.1080/23279095.2025.2539173","url":null,"abstract":"<p><strong>Introduction: </strong>While subjective appraisal of cognition (SAC) has been shown to differ by race, it is unknown whether the consistency between self- and informant reports of cognition varies by race. The present study investigated this gap using a large, community-based cohort of healthy older adults.</p><p><strong>Methods: </strong>Participants and close informants from the National Alzheimer's Coordinating Center reported the presence or absence of participant memory decline. Four groups were created by combining the participants' and informants' appraisal of the participants' cognition. Bayesian contingency tables and <i>t</i>-tests examined racial group differences.</p><p><strong>Results: </strong>Native Americans reported more cases of cognitive decline compared to Black (BF₁₀ = 7) and White (BF₁₀ = 3.6) Americans. No differences in reports of cognitive decline were found between White, Black, and Asian Americans (BF₁₀ < 0.1). There was also strong evidence that Native Americans reported more depressive symptoms compared to Black (BF₁₀ = 10.5) and White (BF₁₀ = 6.3) Americans after correcting for memory complaints.</p><p><strong>Discussion: </strong>Reports of cognitive decline were similar amongst most racial groups, although Native American participants and their close informants reported cognitive decline more frequently. A limited set of objective cognitive measures did not differ between racial groups. However, slightly greater reported depressive symptoms among Native Americans may partially contribute to the observed differences.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-9"},"PeriodicalIF":1.5,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144796071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interaction of neurological disorders and medical comorbidities is associated with an increased rate of incompetency adjudications.","authors":"Dana R Miller, George J Demakis","doi":"10.1080/23279095.2025.2539172","DOIUrl":"https://doi.org/10.1080/23279095.2025.2539172","url":null,"abstract":"<p><strong>Objective: </strong>This study examined if medical comorbidities predict civil competency adjudication.</p><p><strong>Hypotheses: </strong>We hypothesize that individuals with greater comorbidities will be at an increased risk for incompetency. Second, we hypothesize that there will be an interaction of medical comorbidities with neurological conditions, such that those respondents will be more likely adjudicated incompetent than those with psychiatric conditions and/or developmental disabilities. Last, we hypothesize that medical comorbidities will interact with functional abilities to predict incompetency more strongly.</p><p><strong>Methods: </strong>This study used data from 265 court-ordered competency evaluations conducted by one licensed psychologist in North Carolina between 2004 and 2022. Actual legal competency determinations were obtained for 232 individuals with either psychiatric, neurological, combined psychiatric and neurological, or developmentally disabled diagnoses. Medical comorbidity data was extracted from 228 cases using the Charlson Comorbidity Index.</p><p><strong>Results: </strong>We found that individuals adjudicated incompetent tend to have more medical conditions than those deemed competent. However, the impact of medical comorbidities was not equivalent across all respondents. Instead, an interaction effect was observed for patients with neurological conditions and medical comorbidities. With no or low medical comorbidities, the odds of being adjudicated incompetent are significantly higher for those with a psychiatric diagnosis. However, this changes in the context of the high number and severity of medical comorbidities. With these circumstances, neurological patients are significantly more likely to be adjudicated incompetent than psychiatric patients with the same number of medical comorbidities.</p><p><strong>Conclusions: </strong>Our findings suggest that medical comorbidities do not impact all clinical populations equivalently. This provides support for the importance of evaluating how medical comorbidities affect neurological patients' ability to live independently and/or manage their own affairs, over and above their primary condition.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-11"},"PeriodicalIF":1.5,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Gamma Band Power of Electroencephalogram in Alzheimer's disease.","authors":"Vinurajkumar S, Yamuna Devi K, Manikandan K, Sathish S","doi":"10.1080/23279095.2025.2540586","DOIUrl":"https://doi.org/10.1080/23279095.2025.2540586","url":null,"abstract":"<p><p>Gamma transcranial alternating current stimulation (Gamma-tACS) is used for treating Alzheimer's disease (AD). The changes in the Gamma band power (GBP) of Electroencephalogram (EEG) manifested by AD can justify the reliability of enhancing the GBP via the Gamma-tACS. The EEG is the electric potential originating from the neural activity of the human brain. Our objective is to statistically investigate how far the AD patients differ from the healthy subjects in terms of GBP of resting-state EEG at the frontal electrodes. The dataset contains EEG recordings from 65 participants comprising 36 AD patients with an age of 66.39 ± 7.89 and 29 healthy subjects with an age of 67.90 ± 5.40. As a major finding, the Wilcoxon rank-sum test reveals that the difference in GBP of AD patients and healthy subjects is not significant at frontal polar 1 (FP1) (<i>p</i> = 0.81), FP2 (<i>p</i> = 0.48), frontal 3 (F3) (<i>p</i> = 0.77), F7 (<i>p</i> = 0.76), frontal zone (Fz) (<i>p</i> = 0.65), F4 (<i>p</i> = 0.91), and F8 (<i>p</i> = 0.42).</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-7"},"PeriodicalIF":1.5,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A narrative review of clinical stages of psychosis addressing neurocognitive, sleep, and sleep spindle alterations.","authors":"Naksidil Torun Yazıhan","doi":"10.1080/23279095.2025.2539168","DOIUrl":"https://doi.org/10.1080/23279095.2025.2539168","url":null,"abstract":"<p><p>Prodromal phases in psychotic disorders, or pre-psychotic states, constitute a critical window during which cognitive and sleep-related changes emerge, offering important insights into the course of the disorder. Determining underlying mechanisms behind the progression of clinical stages of psychosis requires an understanding of the neurocognitive characteristics, sleep patterns, and sleep spindle features associated with these phases. Sleep spindles are suggested to be strong indicators for predicting general intelligence, memory and basic learning skills in both healthy individuals and clinical groups. Changes in sleep structure, decrease in spindle activity, and disruption of sleep-related learning seem to be important in explaining dysfunction in psychosis. For this reason, defining how these processes are affected during the prodromal period, prior to the first psychotic episode, may provide evidence for the underlying mechanisms of the disorder. In particular, sleep spindles may provide insight into neurophysiological functioning and the disorder's pathophysiology. This narrative review aims to summarize the clinical stages of psychosis, highlight the significance of neurocognitive impairments, and explore the role of sleep spindles in psychotic conditions, as well as their potential implications for future research. A comprehensive analysis of the literature between 1990 and 2025, from major databases including PubMed, Web of Science, PsycINFO, and Scopus, was conducted, with a focus on studies examining clinical stages of psychosis, neurocognitive impairments, changes in sleep, and sleep spindle activity in individuals exhibiting pre-psychotic symptoms.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-8"},"PeriodicalIF":1.5,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144755058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Finger tapping and paratonia assessment in older adults with and without Mild cognitive impairment, motor-cognitive correlations.","authors":"Triantafyllia Kalantzakou, Vasileios Mantas, Eleni Boutsika, Panagiotis Zisis, Efstratios Gallopoulos, Panagiotis Alexopoulos, Nikolaos Scarmeas, Cleanthe Spanaki, Efthimios Dardiotis, Georgia Xiromerisiou","doi":"10.1080/23279095.2025.2533205","DOIUrl":"https://doi.org/10.1080/23279095.2025.2533205","url":null,"abstract":"<p><p>Dementia syndromes involve cognitive but also early motor impairment. Finger tapping is a widely used motor assessment tool and Quantitative parameters may provide insights into the motor-cognitive association. Paratonia is another, frequently observed motor manifestation of dementia. A total of 104 participants underwent motor assessments, including the Unified Parkinson's Disease Rating Scale (UPDRS), quantitative finger tapping, and paratonia scales. Cognitive function was assessed using the Montreal Cognitive Assessment (MoCA) and Mini-Mental State Examination (MMSE). Cognitively Impaired participants exhibited a prolonged strike duration compared to healthy participants. Executive function (EF), correlated with tapping parameters, suggesting shared neural mechanisms. Interestingly, participants with worse memory performance demonstrated greater temporal regularity. Paratonia was prevalent among participants and correlated with age and EF, reinforcing its association with frontal dysfunction. Significant differences were also revealed in motor-cognitive correlations between the two genders. This study provides important information about motor deficits in older adults, highlighting their associations with cognitive decline as well as the influence of gender and age on them. Quantitative assessment of finger tapping also proves to be an objective recorder of motor parameters linked to cognitive impairment. Future longitudinal studies are needed to evaluate the predictive value of these motor parameters in dementia progression.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-16"},"PeriodicalIF":1.4,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144676478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the effects of cognitive stimulation therapy on cognitive status and apathy in older adults with mild cognitive impairment: A randomized controlled trial.","authors":"Ejdane Coşkun, Ayşe İnel Manav","doi":"10.1080/23279095.2025.2527732","DOIUrl":"https://doi.org/10.1080/23279095.2025.2527732","url":null,"abstract":"<p><p>This study was conducted to evaluate the effects of cognitive stimulation therapy on cognitive status and apathy in older adults with mild cognitive impairment. It is a randomized controlled experimental study. The research was conducted in a care center located in a province in Turkey between October 30, 2023, and December 25, 2023. A total of 62 individuals, including 31 in the intervention group and 31 in the control group, were included in the study, forming the research sample. The data for the study were collected using the \"Personal Information Form,\" the \"Standardized Mini-Mental Test (SMMSE),\" and the \" Apathy Rating Scale (ARS).\" Cognitive Stimulation Therapy was administered twice a week for a total of 14 sessions in the form of group therapy. Following the implementation of Cognitive Stimulation Therapy, a comparison between the intervention and control groups revealed significant differences in post-test outcomes. The Standardized Mini-Mental State Examination (SMMSE) post-test scores averaged 24.3 ± 1.3 in the intervention group, whereas the control group recorded a lower mean score of 19.6 ± 1.5. Similarly, in the Alzheimer's Disease Assessment Scale-Cognitive Subscale (ARS), the intervention group achieved a mean score of 47.5 ± 3.5, compared to 36.2 ± 3.0 in the control group. It was determined that the mean scores of individuals in the intervention group increased significantly (<i>p</i> < 0.001). Cognitive Stimulation Therapy has been found to be effective in improving cognitive functions and reducing apathy levels in older adults with mild cognitive impairment. Therefore, it is recommended that psychiatric nurses providing care for geriatric individuals implement Cognitive Stimulation Therapy.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-12"},"PeriodicalIF":1.4,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}