Soraia Silva Monteiro, Andreia Geraldo, Joana O Pinto, Isabel Maria Santos, Nick DeFilippis, Fernando Ferreira-Santos
{"title":"Neuropsychological assessment by video teleconference in adults: A systematic review.","authors":"Soraia Silva Monteiro, Andreia Geraldo, Joana O Pinto, Isabel Maria Santos, Nick DeFilippis, Fernando Ferreira-Santos","doi":"10.1080/23279095.2025.2455538","DOIUrl":"https://doi.org/10.1080/23279095.2025.2455538","url":null,"abstract":"<p><p>Among the diverse advantages that neuropsychological assessment via video teleconference (VTC) presents, increased accessibility and convenience are the most recognized. However, questions remain regarding the impact of VTC on the validity of neuropsychological testing. This systematic review aimed to (a) update the current knowledge of neuropsychological testing validity conducted via VTC in adults; (b) identify factors contributing to variability in results; and (c) recommend best practices for conducting these assessments. A total of 21 crossover studies were analyzed. The samples of these studies included healthy adults and individuals with cognitive impairments, with mean ages ranging from 23 to 81 years. Overall, the results point toward a strong agreement between VTC and in-person assessments. However, some variability was found across domains, with motor and timed tasks being particularly vulnerable to technical problems such as poor video/audio quality, unstable internet connections, limited familiarity with software and inadequacy of some devices. Additional challenges were identified when providing these services to individuals with cognitive impairments, specifically in tasks requiring clear verbal instructions or precise visual details. Further research is essential to establish standardized VTC protocols and administration guidelines, particularly for clinical populations, to mitigate variability and enhance the validity of VTC-based neuropsychological assessment.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-18"},"PeriodicalIF":1.4,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saskia N Craig, Martin Dempster, David Curran, Aoife M Cuddihy, Nigel Lyttle
{"title":"A systematic review of the effectiveness of digital cognitive assessments of cognitive impairment in Parkinson's disease.","authors":"Saskia N Craig, Martin Dempster, David Curran, Aoife M Cuddihy, Nigel Lyttle","doi":"10.1080/23279095.2025.2454983","DOIUrl":"https://doi.org/10.1080/23279095.2025.2454983","url":null,"abstract":"<p><p><b><i>Background</i></b>: Digitalization in healthcare has been extended to how we examine and manage Parkinson's Disease Mild Cognitive Impairment (PD-MCI). <b><i>Methods</i></b>: Moyer Population (those with PD and in some cases control groups), Intervention (digital cognitive test) and Outcome (validity and reliability) (PIO) and Campbell et al. Synthesis Without Meta-analysis (SWiM) methods were employed. A literature search of MEDLINE, PsycINFO, CINAHL, OpenGrey, and ProQuest Theses and Dissertations Sources screened for articles. <b><i>Results</i></b>: The digital trail-making test (dTMT) was the most used measure. There was strong validity between the dTMT and pencil-paper TMT, Mini-Mental State Examination (MMSE), and Montreal Cognitive Assessment (MoCA) scores (ranging from <i>r</i> = .55 to .90, <i>p</i> < .001). Validity between the TMT pencil-paper and digital versions were adequate (ranging from <i>r</i> = .51 to 90, <i>p</i> < .001). Reliability was demonstrated between PD and control groups' scores (ranging from <i>r =</i> .71 to .87). One study found excellent inter-rater reliability (ICC = .90 to .95). The dMoCA was the most used screen that assessed more than two cognitive domains. There was a range in the strength of agreement between digital and pencil-paper versions (ICC scores = .37 to .83) and only one study demonstrated adequate validity (<i>r</i> = .59, <i>p</i> < .001). Poor internal consistency (<i>α</i> = .54) and poor test re-test reliability (between PD and control groups' scores, <i>p</i> > .05) were found. <b><i>Conclusion</i></b>: This review found that digitalized cognitive tests are valid and reliable methods to assess PD-MCI. Considerations for future research are discussed.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-13"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adriana Aguayo Arelis, Jesús Emmanuel Arana Yepez, Brenda Viridiana Rabago Barajas, Fabián Espinosa De Los Monteros Conrique
{"title":"Executive functioning in subjects post COVID-19 infection in Mexico.","authors":"Adriana Aguayo Arelis, Jesús Emmanuel Arana Yepez, Brenda Viridiana Rabago Barajas, Fabián Espinosa De Los Monteros Conrique","doi":"10.1080/23279095.2025.2458684","DOIUrl":"https://doi.org/10.1080/23279095.2025.2458684","url":null,"abstract":"<p><p>Over the past three years, conflicting evidence has emerged regarding the impact of COVID-19 on executive functions and the frontal lobe. In this study, we evaluated executive functions in individuals from the state of Jalisco who had contracted COVID-19. Sixty individuals with a history of mild COVID-19 were included and compared to historical controls from the Mexican population, who had been assessed prior to the pandemic during the validation of the Trail Making Test Form B, the Stroop Color and Word Test, and the Modified Wisconsin Card Sorting Test (M-WCST). The post-infection group exhibited lower scores only on the M-WCST. Therefore, we concluded that individuals who have recovered from mild COVID-19 do not display widespread impairments in executive functions, with the exception of deficits observed on the M-WCST. This suggests possible neurophysiological alterations in the prefrontal cortex during SARS-CoV-2 infection, given that cognitive flexibility is primarily mediated in this region. These findings contribute to the growing body of evidence indicating that even non-hospitalized COVID-19 patients can experience executive function deficits, providing a foundation for further neurophysiological research into the mechanisms underlying this phenomenon.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Normative data for the oral version of the symbol digit modalities test in the French-Quebec population aged 50 years and over.","authors":"Catherine Bouchard, Noémie Girard-Bouchard, Noémie Fontaine, Florence Belzile, Alisone Hébert, Hannah Mulet-Perreault, Joël Macoir, Carol Hudon","doi":"10.1080/23279095.2025.2457998","DOIUrl":"https://doi.org/10.1080/23279095.2025.2457998","url":null,"abstract":"<p><p><b>Introduction</b>: The oral version of the Symbol Digit Modalities Test (SDMT-O) is a prominent measure of information processing speed that can help overcome motor difficulties associated with some conditions. According to previous studies, performance on this test is influenced by various factors such as age, biological sex, educational level, and cultural background. <b>Objective</b>: This study aimed to establish normative data for the SDMT-O in middle-aged and older French-Quebec people. <b>Method</b>: The normative sample comprised 239 healthy individuals aged 50 to 90 years old, exclusively from Quebec, Canada. Statistical analyses examined the associations between age, biological sex, educational level, and the number of correct responses on the SDMT-O. <b>Results</b>: SDMT-O performance was significantly associated with age and educational level, but not with sex. Normative data are presented using regression equations. <b>Conclusions</b>: These norms will be pivotal for evaluating and identifying information processing speed impairments in the middle-aged and older French-Quebec examinees.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-6"},"PeriodicalIF":1.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EEG-derived brainwave patterns for depression diagnosis via hybrid machine learning and deep learning frameworks.","authors":"Nitin Ahire","doi":"10.1080/23279095.2025.2457999","DOIUrl":"https://doi.org/10.1080/23279095.2025.2457999","url":null,"abstract":"<p><p>In the fields of engineering, science, technology, and medicine, artificial intelligence (AI) has made significant advancements. In particular, the application of AI techniques in medicine, such as machine learning (ML) and deep learning (DL), is rapidly growing and offers great potential for aiding physicians in the early diagnosis of illnesses. Depression, one of the most prevalent and debilitating mental illnesses, is projected to become the leading cause of disability worldwide by 2040. For early diagnosis, a patient-friendly, cost-effective approach based on readily observable and objective indicators is essential. The objective of this research is to develop machine learning and deep learning techniques that utilize electroencephalogram (EEG) signals to diagnose depression. Different statistical features were extracted from the EEG signals and fed into the models. Three classifiers were constructed: 1D Convolutional Neural Network (1DCNN), Support Vector Machine (SVM), and Logistic Regression (LR). The methods were tested on a dataset comprising EEG signals from 34 patients with Major Depressive Disorder (MDD) and 30 healthy subjects. The signals were collected under three distinct conditions: TASK, when the subject was performing a task; Eye Close (EC), when the subject's eyes were closed; and Eye Open (EO), when the subject's eyes were open. All three classifiers were applied to each of the three types of signals, resulting in nine (3 × 3) experiments. The results showed that TASK signals yielded the highest accuracies of 88.4%, 89.3%, and 90.21% for LR, SVM, and 1DCNN, respectively, compared to EC and EO signals. Additionally, the proposed methods outperformed some state-of-the-art approaches. These findings highlight the potential of EEG-based approaches for the clinical diagnosis of depression and provide promising avenues for further research. Additionally, the proposed methodology demonstrated statistically significant improvements in classification accuracy, with p-values < 0.05, ensuring robustness and reliability.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-10"},"PeriodicalIF":1.4,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riikka Pihlaja, Henriikka Ollila, Annamari Tuulio-Henriksson, Sanna Koskinen, Viljami Salmela, Marjaana Tiainen, Johanna Hästbacka, Laura Hokkanen
{"title":"Comprehensive neuropsychological assessment and predictors of cognitive functioning at six months after COVID-19 in patients treated in the ICU, regular hospital ward, or isolated at home.","authors":"Riikka Pihlaja, Henriikka Ollila, Annamari Tuulio-Henriksson, Sanna Koskinen, Viljami Salmela, Marjaana Tiainen, Johanna Hästbacka, Laura Hokkanen","doi":"10.1080/23279095.2025.2454352","DOIUrl":"https://doi.org/10.1080/23279095.2025.2454352","url":null,"abstract":"<p><p>Cognitive impairment in patients with COVID-19 has been reported, but findings are inconsistent. This study assessed cognitive functioning 6 months post-infection across three COVID-19 severity groups compared to non-COVID controls. Seventy-two ICU-treated, 49 ward-treated, and 44 home-isolated patients with COVID-19, along with 48 controls, underwent neuropsychological evaluation and assessment of subjective cognitive symptoms, depressive symptoms, and fatigue. Cognitive test scores were compared using ANCOVA. Associations between cognitive functioning and variables including demographics, illness severity, comorbidities, depressive symptoms, fatigue, and ICU-related factors were examined with hierarchical linear regression models. Results showed no significant differences in cognitive test performance of impairment frequencies between COVID-19 groups and controls. However, patients with COVID-19 reported higher levels of subjective cognitive symptoms, depressive symptoms, and fatigue compared to controls. Predictors of cognitive functioning included age, education, and, to a lesser extent, comorbidities. COVID-19 severity, depression, fatigue, or ICU-related variables did not significantly impact performance. These findings suggest that while individual cognitive impairments may exist, overall cognitive functioning in patients with COVID-19 was comparable to controls.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-13"},"PeriodicalIF":1.4,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Type 2 diabetes mellitus: A cross-sectional analysis of glycemic controls and brain health outcomes.","authors":"Chien-Ning Huang, Hsiao-Mei Chen, Bei-Yi Su","doi":"10.1080/23279095.2025.2450084","DOIUrl":"https://doi.org/10.1080/23279095.2025.2450084","url":null,"abstract":"<p><p>In this cross-sectional analysis, we explored how fluctuations in glycemic levels impact executive functions and psychosocial outcomes in patients with type 2 diabetes mellitus (T2DM). The goal was to understand the relationship between glycemic control and both neuropsychological and psychosocial health. We stratified participants into well-controlled and poorly controlled groups based on glycated hemoglobin (HbA1c) levels and variability, including a healthy control group for comparison. The study consisted of neuropsychological tests and psychosocial assessments. Results indicated that the poorly controlled T2DM group experienced significant executive dysfunction and scored lower on the Tower of London, Wisconsin Card Sorting, and Digit Span Tests, reflecting a broader impact on quality of life and resilience. These findings support the importance of maintaining stable glycemic levels for better executive and psychosocial outcomes and highlight the need for regular neuropsychological and psychosocial assessments in diabetes care.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Measuring working memory span with WAIS-IV: Digit sequence is the superior span test.","authors":"Jens Egeland, Olaf Lund, Rune Raudeberg","doi":"10.1080/23279095.2024.2330998","DOIUrl":"https://doi.org/10.1080/23279095.2024.2330998","url":null,"abstract":"<p><p>The Digit Span test has been part of the Wechsler tests from the first version. In the WAIS-IV the Digit Span Sequencing subtest (DSS) was introduced and in the forthcoming WAIS-5 working memory span will also be measured in the visual modality. The present study analyzes WAIS-IV Digit Span, Letter- Number Span (LNS) and WMS-III Spatial Span (SS) performance in a mixed clinical sample, expecting to find that Digit Span Forwards (DSF) lacks sensitivity to the Working Memory impairment evident in D-KEFS Trail Making Test-4 (TMT-4) scores ≤1 SD below normative means in the sample. The results showed DSF score above normative means, Digit Span Backwards (DSB) around mean, while SS and LNS was slightly impaired and DSS impaired at the same level as TMT- 4. A double dissociation was observed in DSF and SS performance between subjects with Language- and Non-verbal learning disorders. Most subjects scored in the average range on the LNS-span and high kurtosis reduced sensitivity. Taking LNS and TMT-4 as criterion measures of WM, regression analyses showed no unique contribution of DSF to the variance in these tests. The study supports prior critiques regarding the composite Digit Span measure and demonstrates that the DSS are more effective than the current version of LNS in identifying reduced Working Memory capacity.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Investigation of applicability and reliability of addenbrooke's cognitive assessment-III with Turkish cultural adaptation.","authors":"Fatma Nur Gülmez, Onur Altuntaş","doi":"10.1080/23279095.2025.2453973","DOIUrl":"https://doi.org/10.1080/23279095.2025.2453973","url":null,"abstract":"","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-6"},"PeriodicalIF":1.4,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiao Fei, Jing Zhang, Yue Shi, Jing Guo, Fan Xie, Yi Zhang
{"title":"Effectively capturing memory deficits: New advances in the use of the In-out-Test for cognitive Test post-stroke.","authors":"Xiao Fei, Jing Zhang, Yue Shi, Jing Guo, Fan Xie, Yi Zhang","doi":"10.1080/23279095.2025.2451627","DOIUrl":"https://doi.org/10.1080/23279095.2025.2451627","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the reliability and validity of the In-Out-Test for detecting episodic memory deficits in stroke patients and explored its potential as a clinical test.</p><p><strong>Methods: </strong>A total of 75 stroke patients and 120 healthy controls underwent tests, including the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), Picture-Based Memory Impairment Screen (PMIS), and In-Out-Test. Reliability metrics (Cronbach's α, inter-scorer reliability, test-retest reliability), criterion validity, corrected item-total correlation, hierarchical regression analysis and ROC curve analysis were performed to determine the sensitivity and specificity of the In-Out-Test.</p><p><strong>Results: </strong>Stroke patients scored lower across all tests (<i>p</i> < 0.001), with the largest difference in the In-Out-Test (<i>d</i> = 0.99). The In-Out-Test correlated strongly with other cognitive tests (<i>r</i> = 0.79-0.85 in stroke patients; <i>r</i> = 0.66-0.78 in controls). It explained an additional 4.5% of variance in MoCA-MIS scores (<i>p</i> < 0.001). Reliability was high (Cronbach's α = 0.835; inter-rater ICCs = 0.911-0.925; test-retest ICCs = 0.764-0.802). ROC analysis showed an AUC of 0.747, with a sensitivity of 0.708 and specificity of 0.680 at a cutoff of 10.5.</p><p><strong>Conclusion: </strong>Preliminary findings indicated that the In-Out-Test showed potential in detecting episodic memory impairments in stroke patients, warranting further validation in larger cohorts.</p>","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-9"},"PeriodicalIF":1.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}