Applied Neuropsychology-Adult最新文献

Neurophysiological and neuropsychological parameters in patients with temporal lobe epilepsy. 颞叶癫痫患者的神经生理学和神经心理学参数。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2023-12-26 DOI: 10.1080/23279095.2023.2297296

Antonio Gangemi, Giulia Picciotto, Carmela Mento, Silvia Cardile, Rosa Angela Fabio

{"title":"Neurophysiological and neuropsychological parameters in patients with temporal lobe epilepsy.","authors":"Antonio Gangemi, Giulia Picciotto, Carmela Mento, Silvia Cardile, Rosa Angela Fabio","doi":"10.1080/23279095.2023.2297296","DOIUrl":"10.1080/23279095.2023.2297296","url":null,"abstract":"Temporal lobe epilepsy (TLE) is the most common type of localization-related epilepsy (LRE) and has been extensively studied in the field of neuropsychology due to its significant association with cognitive impairments. Cognitive decline has long been recognized as a consequence of this form of epilepsy, with previous studies primarily focusing on neurophysiological measures. In this study, both neurophysiological and neuropsychological factors were analyzed in TLE patients compared to healthy control subjects. The Montreal Cognitive Assessment (MoCA) and Mini Mental State Examination (MMSE) tests were used to assess neuropsychological processes, while cognitive event-related potential (ERPs), particularly P300, were employed to analyze neurophysiological parameters. The study involved 21 TLE patients (mean age = 61.43) and 21 healthy control subjects. The results revealing that TLE patients scored significantly lower, indicating deficits in specific cognitive areas. The study also observed abnormalities in the ERPs, particularly in the assessment of P300 amplitude and latency, that may be indicative of underlying neural dysfunction related to attention and cognitive processing. In conclusion, the study provides compelling evidence of the association between TLE and a high incidence of cognitive deficits and decline. By considering both neurophysiological and neuropsychological factors, the study sheds light on the comprehensive impact of TLE on various cognitive domains and emphasizes the importance of early identification and management of cognitive impairments in TLE patients.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1627-1633"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139040884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The diagnostic value of cognitive assessment indicators for mild cognitive impairment (MCI). 轻度认知障碍（MCI）认知评估指标的诊断价值。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2024-02-05 DOI: 10.1080/23279095.2024.2306144

Keyan Han, Wei Liang, Hao Geng, Xinyang Jing, Xuemeng Wang, Yaxin Huo, Wei Li, Anqi Huang, Cuixia An

{"title":"The diagnostic value of cognitive assessment indicators for mild cognitive impairment (MCI).","authors":"Keyan Han, Wei Liang, Hao Geng, Xinyang Jing, Xuemeng Wang, Yaxin Huo, Wei Li, Anqi Huang, Cuixia An","doi":"10.1080/23279095.2024.2306144","DOIUrl":"10.1080/23279095.2024.2306144","url":null,"abstract":"Objective: This study aims to evaluate and analyze the standard diagnostic methods for mild cognitive impairment (MCI).Methods: This study used a prospective case-control study to examine baseline data and diagnostic indicators in a population of elderly with MCI. Based on different cognitive abilities, this study divided MCI and healthy control groups. The diagnostic indicators included CDT, MOCA, MMSE, PSQI, MBI, DST, HAMD, AD-related blood markers, and olfactory testing. The diagnostic value of each indicator was done using the ROC curve.Results: This study included 240 adult participants, 135 in the health group and 105 in the MCI group. A comparison of baseline data revealed statistically significant differences between the two groups regarding age, blood glucose, MMSE, CTD, MOCA, ability to perform daily living, AD-related blood indices and olfactory tests (all p < 0.05). Logistic regression analysis statistically showed that age, MOCA, and CDT were independent diagnostic factors for MCI (all p < 0.05). Combining these three indicators has the best diagnostic specificity (92.54%). AD-related blood and olfactory tests indices had only moderate diagnostic values (AUC: 0.7-0.8).Conclusion: Age, MOCA, and CDT are good indicators for diagnosing early-stage MCI. AD-related blood indices and olfactory tests can serve as valuable adjuncts in diagnosing MCI.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1722-1731"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139693526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3-Year test-retest reliability in Parkinson's disease and healthy older adults: The Parkinson's progression markers initiative study. 帕金森病和健康老年人的 3 年重复测试可靠性：帕金森病进展标记倡议研究。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2024-01-19 DOI: 10.1080/23279095.2024.2303718

Ari Alex Ramos, Liana Machado

{"title":"3-Year test-retest reliability in Parkinson's disease and healthy older adults: The Parkinson's progression markers initiative study.","authors":"Ari Alex Ramos, Liana Machado","doi":"10.1080/23279095.2024.2303718","DOIUrl":"10.1080/23279095.2024.2303718","url":null,"abstract":"Repeated neuropsychological assessments are often conducted in clinical and research settings to track cognitive changes over single or multiple intervals in patients with Parkinson's disease (PD). Yet few studies have documented test-retest reliability in PD. To address this gap, we used data from the Parkinson's Progression Markers Initiative (PPMI) to investigate the reliability of five well-known neuropsychological tests over a 3-year follow-up assessment in early-stage PD with either normal (PD-NC; N = 158) or abnormal (PD-AC; N = 39) cognitive screening, categorized based on recommended cutoffs for the Montreal Cognitive Assessment (MoCA), and healthy older adults (HOA; N = 102). All participants analyzed maintained the same cognitive status category across the assessment points. Intraclass correlation coefficients (ICCs) estimated reliability. The overall ICCs calculated across time points were as follows: Judgment of Line Orientation (PD-NC = .47, PD-AC = .50, HOA = .59); Letter-Number Sequencing (PD-NC = .64, PD-AC = .64, HOA = .65); Semantic Fluency (PD-NC = .69, PD-AC = .89, HOA = .77); Symbol Digit Modalities Test (PD-NC = .67, PD-AC = .83, HOA = .71). For the two primary components of the Hopkins Verbal Learning Test-Revised, we found the following ICCs: immediate recall (PD-NC = .46, PD-AC = .57, HOA = .58); delayed recall (PD-NC = .42, PD-AC = .57, HOA = .54). Findings from this study provide useful information for clinicians and researchers toward selecting suitable neuropsychological tests to monitor cognition at two or more time points among newly diagnosed individuals with PD and HOA.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1678-1690"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139503203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adult norms for the decision-making MindPulse Digital Test. 决策 MindPulse 数字测验的成人标准。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2024-02-14 DOI: 10.1080/23279095.2024.2307413

Jennyfer Ansado, Bertrand Eynard, Nastasia Mirofle, Charlotte Mennetrey, Jasmine Banchereau, Marion Sablon, Eline Lokietek, Florence Le Vourc'h, Juliette Tissot, Jérémy Wrobel, Claire Martel, Sylvie Granon, Sandra Suarez

{"title":"Adult norms for the decision-making MindPulse Digital Test.","authors":"Jennyfer Ansado, Bertrand Eynard, Nastasia Mirofle, Charlotte Mennetrey, Jasmine Banchereau, Marion Sablon, Eline Lokietek, Florence Le Vourc'h, Juliette Tissot, Jérémy Wrobel, Claire Martel, Sylvie Granon, Sandra Suarez","doi":"10.1080/23279095.2024.2307413","DOIUrl":"10.1080/23279095.2024.2307413","url":null,"abstract":"We present adult normalized data for MindPulse (MP), a new tool evaluating attentional and executive functioning (AEF) in decision-making. We recruited 722 neurotypical participants (18-80 years), with 149 retested. The MP test includes three tasks: Simple Reaction Time (SRT), Go/No-go, and complex Go/No-go, involving perceptual components, motor responses, and measurements of reaction time (RT) and correctness. We compare responses, evaluating 14 cognitive indices (including new composite indices to describe AEF: Executive Speed and Reaction to Difficulty). We adjust for age/sex effects, introduce a difficulty scale, and consider standard deviations, aberrant times, and Spearman Correlation for speed-accuracy balance. Wilcoxon unpaired rank test is used to assess sex effects, and linear regression is employed to assess the age linear dependency model on the normalized database. The study demonstrated age and sex effects on RTs, in all three subtests, and the ability to correct it for individual results. The test showed excellent validity (Cronbach Alpha for the three subtasks is 92, 87, 95%) and high internal consistency (p < 0.001 for each subtask significantly faster than the more complex subtask) of the MP across the wide age range. Results showed correlation within the three RT parts of the test (p < .001 for each) and the independence of SRT, RD, and ES indices. The Retest effect was lower than intersubject variance, showing consistency over time. This study highlights the MP test's strong validity on a homogeneous, large adult sample. It emphasizes assessing AEF and Reaction to Difficulty dynamically with high sensitivity.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1732-1750"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139736753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary progressive aphasia and amyotrophic lateral sclerosis (PPA-ALS): A longitudinal case study. 原发性进行性失语和肌萎缩性脊髓侧索硬化症（PPA-ALS）：纵向病例研究。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2024-01-19 DOI: 10.1080/23279095.2024.2302833

Gabrielle Hromas, Carlayne E Jackson, Douglas B Cooper, A Campbell Sullivan

{"title":"Primary progressive aphasia and amyotrophic lateral sclerosis (PPA-ALS): A longitudinal case study.","authors":"Gabrielle Hromas, Carlayne E Jackson, Douglas B Cooper, A Campbell Sullivan","doi":"10.1080/23279095.2024.2302833","DOIUrl":"10.1080/23279095.2024.2302833","url":null,"abstract":"Objective: Approximately 50% of patients with amyotrophic lateral sclerosis (ALS) experience cognitive decline, with frontotemporal dementia (FTD) accounting for up to 15% of these cases. Despite this, there is considerable delay in diagnosis, which affects patient care.Methods: We report longitudinal results of neuropsychological evaluations in a patient diagnosed with non-fluent/agrammatic primary progressive aphasia (nfvPPA) and amyotrophic lateral sclerosis (ALS). The patient, Ms. X, presented with progressive speech difficulties starting in her late-60's. Initial diagnosis was nfvPPA. After 4-5 years of progressive swallowing difficulties, as well as facial weakness, her diagnosis was modified to PPA-ALS.Results: Ms. X underwent neuropsychological evaluations three times over a period of five years. Results of evaluations were intact and stable over time, except for progressive loss of speech impacting her performance on a sentence repetition task.Conclusion: This case study provides valuable insight into the overlap between PPA-ALS from a neuropsychological standpoint. The results reflect preserved cognitive skills in the context of loss of speech and motor abilities. This case study also shows the length of time between onset of symptoms and clear diagnosis, which often requires an immense amount of health literacy and personal advocacy on the part of the patient.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1819-1822"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139503204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Love, anger and Primary Progressive Aphasia: Psychological care for a person with dementia. 爱、愤怒与原发性进行性失语症：痴呆症患者的心理护理。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2024-02-29 DOI: 10.1080/23279095.2024.2322633

George Prigatano

引用次数: 0

Validity and reliability of the Persian version of Mini-Addenbrooke's Cognitive Examination among Iranian highly educated older adults. 在伊朗受过高等教育的老年人中进行的波斯语版迷你艾登布鲁克认知检查的有效性和可靠性。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2024-01-19 DOI: 10.1080/23279095.2024.2303725

Maryam Pourshams, Vahid Rashedi, Mostafa Almasi-Dooghaee, Seyed Kazem Malakouti, Leila Kamalzadeh, Nahid Borna, Athena Enderami, Behnam Shariati

{"title":"Validity and reliability of the Persian version of Mini-Addenbrooke's Cognitive Examination among Iranian highly educated older adults.","authors":"Maryam Pourshams, Vahid Rashedi, Mostafa Almasi-Dooghaee, Seyed Kazem Malakouti, Leila Kamalzadeh, Nahid Borna, Athena Enderami, Behnam Shariati","doi":"10.1080/23279095.2024.2303725","DOIUrl":"10.1080/23279095.2024.2303725","url":null,"abstract":"Background: Limited studies have examined psychometric properties of dementia screening tools in university-educated older adults. We aimed to examine this population's diagnostic accuracy of the Iranian version of Mini-Addenbrooke's Cognitive Examination (M-ACE).Materials & methods: Eighty-seven participants with over 60 years with university education were divided into three groups: Major neurocognitive disorder, mild neurocognitive disorder, and healthy control. The Iranian version of M-ACE, the Mini-Mental State Examination (MMSE), the Geriatric Depression Scale (GDS), the Activities of Daily Living-Instrumental Activities of Daily Living (ADL-IADL) scale and Diagnostic and Statistical Manual of Mental Disorders 5th edition-Text Revision (DSM-5) were used.Results: A high internal reliability of questionnaire was confirmed by Cronbach's alpha coefficient. One-way ANOVA and post hoc analysis confirmed a significant difference between study groups. The scores of M-ACE were found to have a high positive correlation with MMSE, IADL, ADL, and a moderate correlation with GDS. The optimal cutoff score of M-ACE to screen for mild and major neurocognitive disorders were 27.5 and 20.5, respectively.Conclusion: The M-ACE was a concise and reliable tool used to identify neurocognitive disorders in highly educated older adults, but they should be evaluated at a higher traditional cut score in earlier stages.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1691-1697"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139503207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cognitive alterations and brain functional changes following chemotherapy treatment in breast cancer patients: A systematic review on resting-state fMRI studies. 乳腺癌患者化疗后的认知改变和脑功能变化：静息态 fMRI 研究系统综述。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2024-01-23 DOI: 10.1080/23279095.2024.2303362

Lorenzo Conti, Silvia Francesca Maria Pizzoli, Chiara Marzorati, Roberto Grasso, Giuseppe Petralia, Gabriella Pravettoni

{"title":"Cognitive alterations and brain functional changes following chemotherapy treatment in breast cancer patients: A systematic review on resting-state fMRI studies.","authors":"Lorenzo Conti, Silvia Francesca Maria Pizzoli, Chiara Marzorati, Roberto Grasso, Giuseppe Petralia, Gabriella Pravettoni","doi":"10.1080/23279095.2024.2303362","DOIUrl":"10.1080/23279095.2024.2303362","url":null,"abstract":"Cognitive dysfunctions and functional brain modifications are among the side effects reported by breast cancer patients that persist beyond the chemotherapy. This paper aims at synthesizing the evidence on cognitive and functional brain changes and their associations in breast cancer patients treated with chemotherapy. A systematic literature search was performed using PubMed, Ovid MEDLINE, Scopus, and Embase up to July 2022. Eligible studies evaluated adult women with breast cancer treated with systemic chemotherapy, that performed cognitive assessment and resting-state functional MRI. Methodological quality was assessed. Sixteen studies were included, with a total of 1054 female participants. All studies reported alterations mainly concerned the fronto-parieto-temporal system and specifically involved the disruption of the DMN. Consistent with these findings, BCPs showed changes in cognitive performance reporting dysfunctions in executive ability, memory, and attention. However, not all the studies found a significant association between functional brain alterations and cognitive dysfunction. Some limitations including lack of sample homogeneity and different methodological approaches were reported. This work highlighted the presence of cognitive dysfunctions and functional brain alteration in breast cancer patients treated with chemotherapy. This allows a greater awareness of the side effects, promoting better clinical management. However, further research is needed to investigate the cause-effect relationship between cognitive and functional alterations.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1803-1818"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compensatory cognitive training for people with traumatic brain injury: A systematic review of randomized controlled trial. 针对脑外伤患者的补偿性认知训练：随机对照试验的系统回顾。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2024-01-29 DOI: 10.1080/23279095.2024.2306133

Anas R Alashram

{"title":"Compensatory cognitive training for people with traumatic brain injury: A systematic review of randomized controlled trial.","authors":"Anas R Alashram","doi":"10.1080/23279095.2024.2306133","DOIUrl":"10.1080/23279095.2024.2306133","url":null,"abstract":"Cognitive impairments are a common consequence in people with traumatic brain injury (TBI). Compensatory cognitive training is a therapeutic strategy that offers alternative methods to manage cognitive deficits. This systematic review aims to examine the effects of compensatory cognitive training on cognitive function in people with TBI. We searched PubMed, SCOPUS, MEDLINE, PEDro, Web of Science, REHABDATA, and EMBASE from inception until October 2023. The Cochrane Collaboration tool was used to assess the methodological quality of the selected studies. Of 318 articles, eight studies (n = 615), with 8% of participants being females, were included in this review. Four studies were classified as having 'high' quality according to the Cochrane Collaboration tool, while four were categorized as 'moderate' quality. There were variations in treatment protocols and outcome measures, resulting in heterogeneous findings. The effects of compensatory cognitive training on cognitive outcomes showed inconsistency. In conclusion, the evidence for the effects of compensatory cognitive training on cognition in people with TBI is promising. Further trials are needed to investigate the effects of compensatory cognitive training on various cognitive domains in people with TBI.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1794-1802"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139571728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance on the Latin American version of the Face-Name Associative Memory Exam (LAS-FNAME) distinguishes individuals with Mild Cognitive Impairment from age-matched controls in a sample from Argentina. 在阿根廷的一个样本中，拉丁美洲版面-名联想记忆测验（LAS-FNAME）的成绩能将轻度认知障碍患者与年龄匹配的对照组区分开来。

IF 1.5 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-11-01 Epub Date: 2024-03-06 DOI: 10.1080/23279095.2024.2323627

G Keller, N Corvalan, M A Carello, M M Arruabarrena, C Martínez-Canyazo, L De Los Santos, J Spehrs, C Vila-Castelar, R F Allegri, Y T Quiroz, L Crivelli

{"title":"Performance on the Latin American version of the Face-Name Associative Memory Exam (LAS-FNAME) distinguishes individuals with Mild Cognitive Impairment from age-matched controls in a sample from Argentina.","authors":"G Keller, N Corvalan, M A Carello, M M Arruabarrena, C Martínez-Canyazo, L De Los Santos, J Spehrs, C Vila-Castelar, R F Allegri, Y T Quiroz, L Crivelli","doi":"10.1080/23279095.2024.2323627","DOIUrl":"10.1080/23279095.2024.2323627","url":null,"abstract":"Introduction: The Latin American Spanish version of the Face-Name Associative Memory Exam (LAS-FNAME) has shown promise in identifying cognitive changes in those at risk for Alzheimer's disease (AD). However, its applicability for Mild Cognitive Impairment (MCI) detection in the Latin American population remains unexplored. This study aims to analyze the psychometric properties in terms of validity and reliability and diagnostic performance of the LAS-FNAME for the detection of memory disorders in patients with amnestic MCI (aMCI).Materials and methods: The study included 31 participants with aMCI, diagnosed by a neurologist according to Petersen's criteria, and 19 healthy controls. Inclusion criteria for the aMCI group were to be 60 years of age or older, report cognitive complaints, have a memory test score (Craft Story 21) below a -1.5 z-score and have preserved functioning in activities of daily living. Participants completed LAS-FNAME and a comprehensive neuropsychological assessment.Results: LAS-FNAME showed the ability to discriminate against healthy controls from patients with aMCI (AUC= 75) in comparison with a gold-standard memory test (AUC = 69.1). LAS-FNAME also showed evidence of concurrent and divergent validity with a standard memory test (RAVLT) (r = 0.58, p < .001) and with an attention task (Digit Span) (r = -0.37, p = .06). Finally, the reliability index was very high (α = 0.88).Discussion: LAS-FNAME effectively distinguished aMCI patients from healthy controls, suggesting its potential for detecting early cognitive changes in Alzheimer's prodromal stages among Spanish speakers.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1777-1785"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0