Applied Neuropsychology-Adult最新文献_第2页

Right brain hemisphere lesions affecting language functioning in the acute phase of stroke recovery: A Croatian survey. 右脑半球损伤在中风恢复的急性期影响语言功能：克罗地亚的一项调查。

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-01-17 DOI: 10.1080/23279095.2025.2454346

Lara Pilepić, Marina Roje Bedeković

{"title":"Right brain hemisphere lesions affecting language functioning in the acute phase of stroke recovery: A Croatian survey.","authors":"Lara Pilepić, Marina Roje Bedeković","doi":"10.1080/23279095.2025.2454346","DOIUrl":"https://doi.org/10.1080/23279095.2025.2454346","url":null,"abstract":"Greater empirical and scientific attention is still put on patients with left brain hemisphere (LBH) damage where language impairments are common and expected. In patients with RBH damage, language assessment is therefore rarely done in the acute phase of stroke recovery.Purpose: To investigate language impairments in the acute phase of stroke using a Croatian standardized language battery for the first time and compare patients with RBH stroke, LBH stroke and healthy individuals.Methods: This study compares language functioning in three groups of conveniently sampled participants: RBH stroke patients, LBH stroke patients and healthy individuals. Kruskal Wallis H test was used to evaluate a combined group comparison, after which a post-hoc Dunn test was performed.Results: Patients with RBH stroke scored significantly lower than healthy individuals on the CAT:HR in verbal fluency, comprehension of written sentences, naming, and total production. In addition, comprehension of written and spoken sentences did not differ between patients with RBH and LBH stroke patients which suggests the existence of language impairment (p>.05).Conclusion: RBH stroke can significantly impair language comprehension and production in the acute phase of stroke recovery emphasizing the importance of early detection.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-9"},"PeriodicalIF":1.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Theory of mind in trichotillomania: A cross-sectional comparison with healthy controls. 拔毛癖的心理理论：与健康对照的横断面比较。

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-01-16 DOI: 10.1080/23279095.2025.2453492

Aslı Gönül Kaçar, Hasan Demirci, Efruz Pirdoğan Aydın

{"title":"Theory of mind in trichotillomania: A cross-sectional comparison with healthy controls.","authors":"Aslı Gönül Kaçar, Hasan Demirci, Efruz Pirdoğan Aydın","doi":"10.1080/23279095.2025.2453492","DOIUrl":"https://doi.org/10.1080/23279095.2025.2453492","url":null,"abstract":"Background: Theory of mind (ToM) is the ability to make correct inferences from one's own or another person's mental states, such as thoughts, beliefs, desires, and intentions. Although there are a limited number of studies in the literature examining the social cognitive functions of patients with trichotillomania (TTM), no studies have evaluated ToM. This study aimed to compare the ToM skills of patients with TTM and healthy controls.Method: The study included 40 patients who were diagnosed as having TTM according to DSM-5 criteria and 40 healthy controls matched for age, education, and sex. A Sociodemographic and Clinical Data Form, the Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Massachusetts General Hospital Hairpulling Scale (MGH-HPS), Toronto Alexithymia Scale (TAS-20), Reading the Mind in the Eyes Test (RMET), and the Dokuz-Eylül Theory of Mind Scale (DEToMS) were administered to the participants.Results: Patients with TTM performed statistically significantly worse than healthy controls in terms of ToM, metaphor concept, empathic understanding, and faux pas scores. No statistically significant difference was found between the groups in terms of first-degree false belief, second-degree false belief, and irony concept scores. Depression, anxiety, and alexithymia scores of patients with TTM were statistically significantly higher than the control group. No significant correlation was found between ToM tests and anxiety, depression, alexithymia, disease severity, and disease duration in the TTM group.Conclusion: Our findings show that there is an impairment in ToM skills in patients with TTM and that this impairment is independent of clinical features. Studies with larger samples are needed on this subject.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance validity and outcome of treatment in patients with somatic symptom and related disorders (SSRD). 躯体症状及相关疾病（SSRD）患者的治疗效果、有效性和结果。

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-01-11 DOI: 10.1080/23279095.2024.2445715

Marlies van Zwam-van der Wijk, Jeroen J Roor, Rudolf Ponds, Lars de Vroege

{"title":"Performance validity and outcome of treatment in patients with somatic symptom and related disorders (SSRD).","authors":"Marlies van Zwam-van der Wijk, Jeroen J Roor, Rudolf Ponds, Lars de Vroege","doi":"10.1080/23279095.2024.2445715","DOIUrl":"https://doi.org/10.1080/23279095.2024.2445715","url":null,"abstract":"This study addresses the relationship between performance validity and treatment outcome in a sample of patients with somatic symptom and related disorders (SSRD). A retrospective analysis was performed in a sample of 337 patients with SSRD who received treatment. Interaction effects were determined between performance validity test (PVT) performance and raw change scores, reliable change index and clinical change of depression, anxiety and physical symptoms. Performance validity was measured by using the Test of Memory Malingering (TOMM). There was no significant difference between the PVT pass and PVT fail groups in change in depression, anxiety and physical symptoms after treatment. Both groups exhibited a comparable reduction in their symptoms of depression, anxiety and physical symptoms after treatment. There was also no association between PVT performance and raw change scores, reliable clinical changes and clinical changes on depression, anxiety, and physical symptoms. Performance validity was not related to treatment outcome in patients with SSRD, which is a clinically relevant finding. Further studies may want to look into other relevant aspects for determining the potential impact of performance (in)validity on treatment outcome in patients with SSRD, such as treatment drop-out or the number of missed/attended treatment sessions. Alternatively, as treatment outcome is usually determined based on patients' self-report, the impact that non-credible symptom reporting (i.e., symptom validity test failure) has on treatment outcomes is a logical next step for understating the impact of response bias beyond the testing session.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142973239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Virtual reality in clinical evaluation of Unilateral Spatial Neglect, anatomy of current trends: A scoping review. 虚拟现实在单侧空间忽视的临床评估中的应用，当前趋势的剖析：一个范围综述。

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-01-09 DOI: 10.1080/23279095.2024.2439844

Eric Sorita, Noémie C Duclos, Lorina Puech, Quentin Chibaudel, Lisa Quillion-Dupré

{"title":"Virtual reality in clinical evaluation of Unilateral Spatial Neglect, anatomy of current trends: A scoping review.","authors":"Eric Sorita, Noémie C Duclos, Lorina Puech, Quentin Chibaudel, Lisa Quillion-Dupré","doi":"10.1080/23279095.2024.2439844","DOIUrl":"https://doi.org/10.1080/23279095.2024.2439844","url":null,"abstract":"Background: Virtual technologies (VR) could respond to several challenges in Unilateral Spatial Neglect (USN) assessment, particularly the lack of sensitivity and ecological validity of traditional paper-and-pencil tests. A scoping review was conducted to explore current trends in this area.Methods: PubMed, EMBASE, PsycINFO, Web of Science, IEEE, ACM, and the Cochrane Library were systematically searched for VR USN assessment. The Joanna Briggs Institute methodological guidelines for scoping reviews were used to inform our methodology.Results: Thirty-one publications were included. There were two populations: healthy adults (n = 349) and post-stroke individuals (n = 903). A classification based on tasks and type of interaction used was proposed. Correlations with paper and pencil tests (PPTs) were often significant when the task structure was similar to PPTs but was lacking for activities with more dynamic components. The ecological validity of the tasks was assessed in comparison with the Catherine Bergego Scale (n = 4) and a real-world navigation task (n = 1). Using VR, USN disorders have been characterized using a wide range of indicators.Conclusions: Few studies have addressed ecological validity, yet the use of VR in the assessment of the USN in this scoping review shows an undeniable contribution compared to traditional pencil-paper tests, especially for capturing the patient's behavior toward the far extrapersonal space, essential in daily life.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-14"},"PeriodicalIF":1.4,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cultural bias in the assessment of language: A closer look at the Boston naming test among multicultural Canadian older adults. 语言评估中的文化偏见：对多元文化加拿大老年人的波士顿命名测试的进一步观察。

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-01-09 DOI: 10.1080/23279095.2024.2449172

Komal T Shaikh, K B Zaidi, Daniela Wong Gonzalez, Christina Dimech, Zoë M Gilson, Kathryn A Stokes, Theone S E Paterson

{"title":"Cultural bias in the assessment of language: A closer look at the Boston naming test among multicultural Canadian older adults.","authors":"Komal T Shaikh, K B Zaidi, Daniela Wong Gonzalez, Christina Dimech, Zoë M Gilson, Kathryn A Stokes, Theone S E Paterson","doi":"10.1080/23279095.2024.2449172","DOIUrl":"https://doi.org/10.1080/23279095.2024.2449172","url":null,"abstract":"Objective: The Boston Naming Test (BNT) is commonly used to assess word-finding in older adults but performance may be impacted by cultural and linguistic factors. This study aimed to assess cultural bias in BNT performance among older adults, explore sources of this bias and provide clinical guidelines for its use in multicultural settings.Methods: We conducted a retrospective chart review of 525 older adults referred for neuropsychological assessment at a large geriatric hospital in a multicultural Canadian city. Participants were categorized by birthplace (Canada vs. outside Canada), and relationships between BNT scores, years in Canada, sociodevelopmental context of region of birth and first-language status were examined.Results: Individuals born outside of Canada had significantly lower BNT scores than Canadian-born participants. These differences were not fully explained by English as a first language status or age at immigration though a significant correlation was observed between BNT scores and years in Canada. Sociodevelopmental context, measured by the Historical Index of Human Development (HIHD), partially mediated the relationship between region of birth and BNT performance.Conclusions: The BNT is influenced by cultural and linguistic factors, which may lead to inaccurate cognitive assessment in diverse populations. Clinicians should interpret BNT scores with caution in multicultural contexts and consider sociocultural factors to improve diagnostic accuracy and cultural sensitivity.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-13"},"PeriodicalIF":1.4,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anxiety symptoms are distinctly related to working memory deficits in adults with ADHD. 成人ADHD患者的焦虑症状与工作记忆缺陷明显相关。

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-01-06 DOI: 10.1080/23279095.2024.2449170

Andrew A Rauch, Jason R Soble, Rebecca L Silton

{"title":"Anxiety symptoms are distinctly related to working memory deficits in adults with ADHD.","authors":"Andrew A Rauch, Jason R Soble, Rebecca L Silton","doi":"10.1080/23279095.2024.2449170","DOIUrl":"https://doi.org/10.1080/23279095.2024.2449170","url":null,"abstract":"Working memory (WM), the cognitive system that briefly stores and updates information during complex tasks, is one of the most consistently identified neurocognitive deficits in individuals with ADHD. WM deficits are linked to significant challenges in daily life. Adults with ADHD often experience co-occurring anxiety and mood disorders, which are associated with more severe clinical presentations and greater WM deficits. Disentangling how co-occurring depression and anxiety symptoms uniquely contribute to WM deficits in individuals with ADHD is critical for tailoring effective, evidence-based interventions and treatments. This study used a regression approach to explore the relationships among anxiety, depression symptoms, and WM performance in adults with ADHD (n = 439) referred for neuropsychological evaluation at a Midwestern academic medical center. ADHD diagnostic group (ADHD-I and ADHD-C; Predominately Inattentive presentation, and Combined presentation, respectively), depression symptoms, and anxiety symptoms were modeled as predictors of WM performance, with education as a covariate, as education is linked to better cognitive performance. Anxiety and education significantly predicted WM performance, while depression did not, highlighting distinct effects. Anxiety was associated with poorer WM performance, whereas education was linked to better WM. These results emphasize the need for clinical assessments that account for the impacts of specific symptoms on WM in adults with ADHD.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-13"},"PeriodicalIF":1.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Accelerated long-term forgetting: Design and validation of a neuropsychological tool in healthy subjects and diagnostic accuracy in a group of subjects with severe acquired brain injury. 加速长期遗忘：一种神经心理学工具在健康受试者中的设计和验证，以及在一组严重后天性脑损伤受试者中的诊断准确性。

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-01-06 DOI: 10.1080/23279095.2024.2449564

Giulia Pieracci, Federica Satriano, Antonio Liberatore D'Agostino, Marta Rodini, Carlo Caltagirone, Rita Formisano, Vincenzo Vinicola, Giovanni Augusto Carlesimo

{"title":"Accelerated long-term forgetting: Design and validation of a neuropsychological tool in healthy subjects and diagnostic accuracy in a group of subjects with severe acquired brain injury.","authors":"Giulia Pieracci, Federica Satriano, Antonio Liberatore D'Agostino, Marta Rodini, Carlo Caltagirone, Rita Formisano, Vincenzo Vinicola, Giovanni Augusto Carlesimo","doi":"10.1080/23279095.2024.2449564","DOIUrl":"https://doi.org/10.1080/23279095.2024.2449564","url":null,"abstract":"Objective: Accelerated Long-term Forgetting (ALF) is a phenomenon characterized by abnormal memory forgetting over hours or days, despite normal initial acquisition. Because standardized memory assessments typically test memory retention over delays of up to 30 minutes, ALF may be undetected.Methods: The first Experiment of the present study was aimed to validate, in a sample of healthy subjects (n = 54, 20 to 79 years old), a long-term verbal and visuospatial memory procedure, using common tests but administered at extended intervals. In Experiment 2, we aimed to explore ALF pattern in a sample of patients with severe Acquired Brain Injury (sABI) who subjectively complained of memory difficulties and nevertheless obtained normal or only mildly deficient scores on traditional memory tasks (n = 10).Results: Results of Experiment 1 showed that both the verbal and visuo-spatial memory tasks proved to be valid and effective at illustrating the phenomenon of forgetting along the time intervals considered. Moreover, a significant association was found between higher saving scores passing from the 30 min to the 24 hr interval of the verbal test and the score obtained on a questionnaire assessing the subjective feeling of memory functioning. Results of Experiment 2 showed that patients with sABI obtained reduced 30 m-24hr saving scores on the verbal test as compared to healthy controls despite comparable forgetting at earlier and later delays.Conclusions: These findings support the utility of extended memory assessment, thus the need for validation of specific diagnostic tools in clinical practice.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-13"},"PeriodicalIF":1.4,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of the strategy game Mangala on cognitive function, anxiety, depression, and fine motor skills in individuals with Alzheimer's disease: A randomized controlled trial. 策略游戏Mangala对阿尔茨海默病患者认知功能、焦虑、抑郁和精细运动技能的影响：一项随机对照试验

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2025-01-02 DOI: 10.1080/23279095.2024.2448503

Aziz Dengiz, Nilufer Cetisli-Korkmaz, Aysegul Kitis

{"title":"Effect of the strategy game Mangala on cognitive function, anxiety, depression, and fine motor skills in individuals with Alzheimer's disease: A randomized controlled trial.","authors":"Aziz Dengiz, Nilufer Cetisli-Korkmaz, Aysegul Kitis","doi":"10.1080/23279095.2024.2448503","DOIUrl":"https://doi.org/10.1080/23279095.2024.2448503","url":null,"abstract":"Cognitive impairment, changes in mood, and decrease in fine motor skills are some of the most common symptoms experienced by individuals with Alzheimer's Disease (AD). This study aimed to investigate the effects of the Turkish intelligence and strategy game Mangala on cognitive functions, anxiety, depression, and fine motor skills in individuals with AD. In this randomized controlled study, 37 participants were divided into Mangala Group (MG) and Control Group (CG). Both the MG (n = 18) and the CG (n = 19) attended daily physiotherapy and rehabilitation sessions. Additionally, the MG played Mangala 2 sessions/week for six weeks. The mood state was evaluated using the Hospital Anxiety and Depression Scale (HAD), cognitive functions were examined using the Montreal Cognitive Assessment Scale (MoCA), and fine motor skills were measured using the Nine Hole Peg Test (NHPT). There was no significant difference between the groups pretreatment in terms of MoCA, depression and NHPT values (p > .05), except anxiety levels (p= .009) The MG showed significant improvement post-treatment in terms of MoCA and HAD anxiety (p =.0001 and p =.0008), HAD depression and fine motor skills (p =.043 and p =.0001). There were significant improvements in favor of MG in MoCA (p =.014) and NHPT (p =.004), but not in HAD anxiety (p =.782) and depression (p =.514) scores in terms of delta (difference between pre and post treatment) values. To prevent cognitive decline, reduce depression, and improve fine motor skills in patients with AD, The Mangala game may be a good alternative.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-8"},"PeriodicalIF":1.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Semantic knowledge of social norms in frontotemporal dementia patients with either predominant frontal or temporal lobe atrophy. 以额叶或颞叶萎缩为主的额颞叶痴呆患者的社会规范语义知识。

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2024-12-30 DOI: 10.1080/23279095.2024.2447041

Ahmad Alsemari, Jason Osher, Ronald E Cobb

{"title":"Semantic knowledge of social norms in frontotemporal dementia patients with either predominant frontal or temporal lobe atrophy.","authors":"Ahmad Alsemari, Jason Osher, Ronald E Cobb","doi":"10.1080/23279095.2024.2447041","DOIUrl":"10.1080/23279095.2024.2447041","url":null,"abstract":"Objective: Little is known about the relative contribution of frontal and anterior temporal lobes in semantic knowledge of social norms in frontotemporal dementia (FTD). Therefore, this study examined performance of FTD patients with either frontal (F-FTD, left temporal (LT-FTD) or bitemporal lobe atrophy (BT-FTD) on the Social Norms Questionnaire (SNQ) and explored what accounts for the variance in the SNQ-break norm subscale (i.e., endorsement of inappropriate behaviors).Methods: Using data from the National Alzheimer's Coordinating Center (NACC), groups were matched for age and education and included (a) 24 F-FTD patients, (b) 15 LT-FTD patients, (c) 17 BT-FTD patients, and (d) 188 older controls with normal cognition (NC).Results: The BT-FTD group had significantly higher SNQ break norm score than F-FTD and NC groups with a medium effect size, which was also positively associated with the severity personality changes in the real world. Interestingly, the F-FTD and LT-FTD groups performed similarly to the NC group. Regression analysis showed that approximately 21.2% of the variance in SNQ break norms subscale score performance was explained by performance on verb naming.Conclusions: Social inappropriateness in FTD may partially arise from a deficit in knowledge of normative behavior.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-9"},"PeriodicalIF":1.4,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cortical and subcortical gray matter volume and cognitive impairment in Parkinson's disease. 帕金森病的皮层和皮层下灰质体积与认知障碍。

IF 1.4 4区心理学

Applied Neuropsychology-Adult Pub Date : 2024-12-27 DOI: 10.1080/23279095.2024.2443591

Naser Moradi, Siamak Shahidi, Mohammad Ahmadpanah, Sajjad Farashi, Ghodratollah Roshanaei

{"title":"Cortical and subcortical gray matter volume and cognitive impairment in Parkinson's disease.","authors":"Naser Moradi, Siamak Shahidi, Mohammad Ahmadpanah, Sajjad Farashi, Ghodratollah Roshanaei","doi":"10.1080/23279095.2024.2443591","DOIUrl":"https://doi.org/10.1080/23279095.2024.2443591","url":null,"abstract":"Introduction: This study investigated the cortical and subcortical gray matter volume (GMV) and cognitive impairment (CI) in patients with Parkinson's disease (PD).Methods: In this study, T1-weighted magnetic resonance imaging of the cortex and subcortex was conducted on 92 individuals diagnosed with PD and 92 healthy controls (HCs). PD patients were divided into three groups: PD with normal cognition (PD-NC, n = 21), PD with mild CI (PD-MCI, n = 43), and PD with severe CI (PD-SCI, n = 28). Differences in GMV were analyzed using voxel-based morphometry (VBM). Statistical analysis was conducted using SPSS 26.Results: Compared to the HCs, the PD-NC group exhibited reduced GMV in the right middle frontal gyrus (RMFG), right precentral gyrus medial segment (RPGMS), left temporal pole, and right superior frontal gyrus medial segment (RSFGMS). In comparison to the HC and PD-NC groups, the PD-MCI and PD-SCI groups (respectively) demonstrated significant decreases in GMV in the right caudate, left hippocampus, left thalamus, RMFG, RPGMS, RSFGMS, and cerebellum (right crus I and left crus I). The regression analysis indicated that changes in the GMV of the frontal areas can predict cognitive test outcomes.Conclusion: Compared to HCs, PD patients with CI presented significant volume reductions in the RC, LH, LT, RMFG, RPGMS, RSFGMS, and the right and left crus I regions. Consequently, as average GMV atrophy increased in the specified regions, PD patients exhibited more severe cognitive impairment than the HC group. This may be attributed to the initial pathological loss of frontal GMV (especially in the RMFG and RPGMS regions), which could subsequently lead to subcortical dysfunction.","PeriodicalId":51308,"journal":{"name":"Applied Neuropsychology-Adult","volume":" ","pages":"1-14"},"PeriodicalIF":1.4,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0