Cognitive Neuropsychiatry最新文献

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The effect of voice content and social context on shame: a simulation and vignette paradigm to evaluate auditory verbal hallucinations. 语音内容和社会情境对羞耻感的影响:一个评估听觉言语幻觉的模拟和小插曲范式。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-03-01 Epub Date: 2021-08-06 DOI: 10.1080/13546805.2021.1962265
Catherine Bortolon, Martin J Dorahy, Rachel Brand, Clément Dondé, Sophie Slovak, Stéphane Raffard
{"title":"The effect of voice content and social context on shame: a simulation and vignette paradigm to evaluate auditory verbal hallucinations.","authors":"Catherine Bortolon,&nbsp;Martin J Dorahy,&nbsp;Rachel Brand,&nbsp;Clément Dondé,&nbsp;Sophie Slovak,&nbsp;Stéphane Raffard","doi":"10.1080/13546805.2021.1962265","DOIUrl":"https://doi.org/10.1080/13546805.2021.1962265","url":null,"abstract":"<p><strong>Introduction: </strong>Recent theoretical models and preliminary data suggest that shame is a central emotion in the context of auditory verbal hallucinations (AVH or voice-hearing). Nevertheless, all previous studies were correlational. Thus, the present study sought to explore whether simulated AVH experiences can trigger shame using an experimental design.</p><p><strong>Methods: </strong>346 participants from the general population were randomised to one of 6 conditions. They had to read a vignette describing a character who was either in a situation alone or with a close friend. While reading the vignettes, participants also heard either negative or neutral simulated voices or non-voice neutral sounds. Subsequently, participants completed different measures, including shame.</p><p><strong>Results: </strong>Our results showed that both the negative and neutral simulated voice-hearing triggered higher levels of shame, but also other negative emotions when compared to ambient sound, regardless of the social context. Participants in the simulated voice-hearing conditions reported higher levels of maladaptive coping strategies and negative beliefs about voices than in the ambient sound condition.</p><p><strong>Conclusions: </strong>The simulation of neutral and negative voices trigger similar levels of subjective shame, indicating the effect is not specific to negative voices but rather associated with the experience <i>per se</i>. Nevertheless, it can also trigger other negative emotions.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 2-3","pages":"122-138"},"PeriodicalIF":1.7,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1962265","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39278939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
The perceived salience of vocal emotions is dampened in non-clinical auditory verbal hallucinations. 在非临床听觉语言幻觉中,声音情绪的感知显著性受到抑制。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-03-01 Epub Date: 2021-07-14 DOI: 10.1080/13546805.2021.1949972
Maria Amorim, Magda S Roberto, Sonja A Kotz, Ana P Pinheiro
{"title":"The perceived salience of vocal emotions is dampened in non-clinical auditory verbal hallucinations.","authors":"Maria Amorim,&nbsp;Magda S Roberto,&nbsp;Sonja A Kotz,&nbsp;Ana P Pinheiro","doi":"10.1080/13546805.2021.1949972","DOIUrl":"https://doi.org/10.1080/13546805.2021.1949972","url":null,"abstract":"<p><p><i>Introduction:</i> Auditory verbal hallucinations (AVH) are a cardinal symptom of schizophrenia but are also reported in the general population without need for psychiatric care. Previous evidence suggests that AVH may reflect an imbalance of prior expectation and sensory information, and that altered salience processing is characteristic of both psychotic and non-clinical voice hearers. However, it remains to be shown how such an imbalance affects the categorisation of vocal emotions in perceptual ambiguity.<i>Methods:</i> Neutral and emotional nonverbal vocalisations were morphed along two continua differing in valence (anger; pleasure), each including 11 morphing steps at intervals of 10%. College students (<i>N </i>= 234) differing in AVH proneness (measured with the Launay-Slade Hallucination Scale) evaluated the emotional quality of the vocalisations.<i>Results:</i> Increased AVH proneness was associated with more frequent categorisation of ambiguous vocalisations as 'neutral', irrespective of valence. Similarly, the perceptual boundary for emotional classification was shifted by AVH proneness: participants needed more emotional information to categorise a voice as emotional.<i>Conclusions:</i> These findings suggest that emotional salience in vocalisations is dampened as a function of increased AVH proneness. This could be related to changes in the acoustic representations of emotions or reflect top-down expectations of less salient information in the social environment.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 2-3","pages":"169-182"},"PeriodicalIF":1.7,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1949972","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39184339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Cognition, hallucination severity and hallucination-specific insight in neurodegenerative disorders and eye disease. 神经退行性疾病和眼病的认知、幻觉严重程度和幻觉特异性洞察力。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-03-01 Epub Date: 2021-08-02 DOI: 10.1080/13546805.2021.1960812
Marcella Montagnese, Miriam Vignando, Daniel Collerton, Dominic Ffytche, Urs Peter Mosimann, John-Paul Taylor, Katrina daSilva Morgan, Prabitha Urwyler
{"title":"Cognition, hallucination severity and hallucination-specific insight in neurodegenerative disorders and eye disease.","authors":"Marcella Montagnese,&nbsp;Miriam Vignando,&nbsp;Daniel Collerton,&nbsp;Dominic Ffytche,&nbsp;Urs Peter Mosimann,&nbsp;John-Paul Taylor,&nbsp;Katrina daSilva Morgan,&nbsp;Prabitha Urwyler","doi":"10.1080/13546805.2021.1960812","DOIUrl":"https://doi.org/10.1080/13546805.2021.1960812","url":null,"abstract":"<p><p><b>Introduction:</b> Hallucinations occur across neurodegenerative disorders, with increasing severity, poorer cognition and impaired hallucination-specific insight associated with worse outcomes and faster disease progression. It remains unclear how changes in cognition, temporal aspects of hallucinations, hallucination-specific insight and distress relate to each other.<b>Methods:</b> Extant samples of patients experiencing visual hallucinations were included in the analyses: Parkinson's Disease (<i>n</i> = 103), Parkinson's Disease Dementia (<i>n</i> = 41), Dementia with Lewy Bodies (<i>n</i> = 27) and Eye Disease (<i>n</i> = 113). We explored the relationship between factors of interest with Spearman's correlations and random-effect linear models.<b>Results:</b> Spearman's correlation analyses at the whole-group level showed that higher hallucination-specific insight was related to higher MMSE score (<i>r</i><sub>s</sub> = 0.39, <i>p</i> < 0.001) and less severe hallucinations (<i>r</i><sub>s</sub> = -0.28, <i>p</i> < .01). Linear mixed-models controlling for diagnostic group showed that insight was related to higher MMSE (<i>p</i> < .001), to hallucination severity (<i>p</i> = 0.003), and to VH duration (<i>p</i> = 0.04). Interestingly, insight was linked to the distress component but not the frequency component of severity. No significant relationship was found between MMSE and hallucination severity in these analyses.<b>Conclusion:</b> Our findings highlight the importance of hallucination-specific insight, distress and duration across groups. A better understanding of the role these factors play in VH may help with the development of future therapeutic interventions trans-diagnostically.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 2-3","pages":"105-121"},"PeriodicalIF":1.7,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1960812","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39267095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Thinking about hallucinations: why philosophy matters. 思考幻觉:为什么哲学很重要。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-03-01 Epub Date: 2021-12-07 DOI: 10.1080/13546805.2021.2007067
Sam Wilkinson, Huw Green, Stephanie Hare, Joseph Houlders, Clara Humpston, Benjamin Alderson-Day
{"title":"Thinking about hallucinations: why philosophy matters.","authors":"Sam Wilkinson,&nbsp;Huw Green,&nbsp;Stephanie Hare,&nbsp;Joseph Houlders,&nbsp;Clara Humpston,&nbsp;Benjamin Alderson-Day","doi":"10.1080/13546805.2021.2007067","DOIUrl":"https://doi.org/10.1080/13546805.2021.2007067","url":null,"abstract":"<p><p><b>Introduction:</b> Hallucinations research is increasingly incorporating philosophy or the work of philosophically trained individuals. We present three different ways in which this is successfully implemented to the enhancement of knowledge and understanding of hallucinations and related phenomena.<b>Method:</b> We review contributions from phenomenology, philosophy of cognitive science, and philosophy of science and psychiatry.<b>Results:</b> We demonstrate that these areas of philosophy make significant contributions to hallucinations research. Phenomenology gives us a sophisticated and critical understanding of the lived experience of hallucinations. Philosophy of cognitive science enables big-picture theorising and synthesis of ideas, as well as a critical engagement with new paradigms. Philosophy of science and psychiatry raises valuable and theoretically informed questions about diagnosis and categorisation.<b>Conclusions:</b> These contributions reflect both the methodological variety within philosophy and its relevance to the hallucinations researcher.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 2-3","pages":"219-235"},"PeriodicalIF":1.7,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39699367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Auditory verbal hallucinations and childhood trauma subtypes across the psychosis continuum: a cluster analysis. 跨精神病连续体的听觉言语幻觉和儿童创伤亚型:聚类分析。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-03-01 Epub Date: 2021-05-13 DOI: 10.1080/13546805.2021.1925235
M J H Begemann, I E Sommer, R M Brand, P P Oomen, A Jongeneel, J Berkhout, R E Molenaar, N N Wielage, W L Toh, S L Rossell, I H Bell
{"title":"Auditory verbal hallucinations and childhood trauma subtypes across the psychosis continuum: a cluster analysis.","authors":"M J H Begemann,&nbsp;I E Sommer,&nbsp;R M Brand,&nbsp;P P Oomen,&nbsp;A Jongeneel,&nbsp;J Berkhout,&nbsp;R E Molenaar,&nbsp;N N Wielage,&nbsp;W L Toh,&nbsp;S L Rossell,&nbsp;I H Bell","doi":"10.1080/13546805.2021.1925235","DOIUrl":"https://doi.org/10.1080/13546805.2021.1925235","url":null,"abstract":"<p><p><b>Introduction:</b> A strong link between voice-hearing experience and childhood trauma has been established. The aim of this study was to identify whether there were unique clusters of childhood trauma subtypes in a sample across the clinical spectrum of auditory verbal hallucinations (AVH) and to examine clinical and phenomenological features across these clusters.<b>Methods:</b> Combining two independent international datasets (the Netherlands and Australia), childhood trauma subtypes were examined using hierarchical cluster analysis. Clinical and phenomenological characteristics were compared across emerging clusters using MANOVA and chi-squared analyses.<b>Results:</b> The total sample (<i>n</i> = 413) included 166 clinical individuals with a psychotic disorder and AVH, 122 non-clinical individuals with AVH and 125 non-clinical individuals without AVH. Three clusters emerged: (1) low trauma (<i>n</i> = 299); (2) emotion-focused trauma (<i>n</i> = 71); (3) multi-trauma (<i>n</i> = 43). The three clusters differed significantly on their AVH ratings of amount of negative content, with trend-level effects for loudness, degree of negative content and degree of experienced distress. Furthermore, perceptions of voices being malevolent, benevolent and resistance towards voices differed significantly.<b>Conclusion:</b> The data revealed different types of childhood trauma had different relationships between clinical and phenomenological features of voice-hearing experiences. Thus, implicating different mechanistic pathways and a need for tailored treatment approaches.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 2-3","pages":"150-168"},"PeriodicalIF":1.7,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1925235","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38975132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Arts-based methods for hallucination research. 基于艺术的幻觉研究方法。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-03-01 Epub Date: 2021-10-28 DOI: 10.1080/13546805.2021.1993807
Katie Melvin, Colleen P E Rollins, John Cromby, Jon Crossley, Jane R Garrison, Graham K Murray, John Suckling
{"title":"Arts-based methods for hallucination research.","authors":"Katie Melvin,&nbsp;Colleen P E Rollins,&nbsp;John Cromby,&nbsp;Jon Crossley,&nbsp;Jane R Garrison,&nbsp;Graham K Murray,&nbsp;John Suckling","doi":"10.1080/13546805.2021.1993807","DOIUrl":"https://doi.org/10.1080/13546805.2021.1993807","url":null,"abstract":"<p><strong>Introduction: </strong>Neurocognitive models of hallucinations posit theories of misattribution and deficits in the monitoring of mental or perceptual phenomena but cannot yet account for the subjective experience of hallucinations across individuals and diagnostic categories. Arts-based research methods (ABRM) have potential for advancing research, as art depicts experiences which cognitive neuropsychiatry seeks to explain.</p><p><strong>Methods: </strong>To examine how incorporating ABRM may advance hallucination research and theories, we explore data on the lived experiences of hallucinations in psychiatric and neurological populations. We present a multiple case study of two empirical ABRM studies, which used participant-generated artwork and artist collaborations alongside interviews.</p><p><strong>Results: </strong>ABRM combined with interviews illustrated that hallucinations were infused with sensory features, characterised by embodiment, and situated within lived circumstances. These findings advance neurocognitive models of hallucinations by nuancing their multimodal nature, illustrating their embodied feelings, and exploring their content and themes. The process of generating artworks aided in disclosing difficult to discuss hallucinations, promoted participant self-reflection, and clarified multimodal details that may have been misconstrued through interview alone. ABRM were relevant and acceptable for participants and researchers.</p><p><strong>Conclusion: </strong>ABRM may contribute to the development of neurocognitive models of hallucinations by making hallucination experiences more visible, tangible, and accessible.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 2-3","pages":"199-218"},"PeriodicalIF":1.7,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39567371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Increasing motivation in effort-based decision-making tasks: effects of salience and reward expectancy manipulations. 在基于努力的决策任务中增加动机:显著性和奖励预期操纵的影响。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-01-01 Epub Date: 2021-11-23 DOI: 10.1080/13546805.2021.2007068
Katharina E Renz, Matthias Pillny, Tania M Lincoln
{"title":"Increasing motivation in effort-based decision-making tasks: effects of salience and reward expectancy manipulations.","authors":"Katharina E Renz,&nbsp;Matthias Pillny,&nbsp;Tania M Lincoln","doi":"10.1080/13546805.2021.2007068","DOIUrl":"https://doi.org/10.1080/13546805.2021.2007068","url":null,"abstract":"<p><strong>Background: </strong>A significant proportion of patients with affective and psychotic disorders show a marked reduction in goal-directed behaviour, which is also reflected in the behavioural outcomes of effort-based decision-making paradigms. The factors underlying this reduction are not yet fully understood. Reward salience and reward expectancy have been discussed as factors that potentially influence approach behaviour. The aim of this study was thus to test their effects on behaviour in an effort-based decision-making paradigm.</p><p><strong>Methods: </strong>In two studies with community samples we applied a modified version of the Balloon Task. In study 1, we manipulated reward salience in a within-subject design (<i>N</i> = 32) by highlighting the monetary rewards. In study 2, we manipulated reward expectancy in a between-subject design (<i>N</i> = 72) by adding five practice trials with either positive or negative feedback prior to the task.</p><p><strong>Results: </strong>The salience of rewards manipulation significantly increased effort expenditure and the allocation of effort to the level of rewards whereas the reward expectancy manipulation did not.</p><p><strong>Conclusions: </strong>The finding that increasing the salience of rewards increases motivated behaviour in an effort-based decision-making paradigm offers promising possibilities for intervention in disorders characterised by motivational deficits, such asaffective and psychotic disorders.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 1","pages":"20-34"},"PeriodicalIF":1.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39761866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Relationship between neurocognition and theory of mind as a function of symptomatic profile in schizophrenia: results from the national FACE-SZ cohort. 精神分裂症患者神经认知和心理理论作为症状特征的关系:来自全国FACE-SZ队列的结果。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-01-01 Epub Date: 2021-12-09 DOI: 10.1080/13546805.2021.2011184
Sébastien Rambeau, Sarah Del Goleto, Baptiste Pignon, Mohamed Lajnef, Jean Petrucci, Andreï Szöke, Guillaume Fond, Christophe Lançon, Jean-Michel Dorey, Romain Rey, Amandine Garbisson, Delphine Capdevielle, Sylvain Leignier, Julien Dubreucq, Jasmina Mallet, Caroline Dubertret, Mathieu Urbach, Eric Brunet-Gouet, Bruno Aouizerate, David Misdrahi, Anna Zinetti-Bertschy, Julie Clauss, Pierre-Michel Llorca, Isabelle Chereau, Marion Leboyer, Paul Roux, Franck Schürhoff
{"title":"Relationship between neurocognition and theory of mind as a function of symptomatic profile in schizophrenia: results from the national FACE-SZ cohort.","authors":"Sébastien Rambeau,&nbsp;Sarah Del Goleto,&nbsp;Baptiste Pignon,&nbsp;Mohamed Lajnef,&nbsp;Jean Petrucci,&nbsp;Andreï Szöke,&nbsp;Guillaume Fond,&nbsp;Christophe Lançon,&nbsp;Jean-Michel Dorey,&nbsp;Romain Rey,&nbsp;Amandine Garbisson,&nbsp;Delphine Capdevielle,&nbsp;Sylvain Leignier,&nbsp;Julien Dubreucq,&nbsp;Jasmina Mallet,&nbsp;Caroline Dubertret,&nbsp;Mathieu Urbach,&nbsp;Eric Brunet-Gouet,&nbsp;Bruno Aouizerate,&nbsp;David Misdrahi,&nbsp;Anna Zinetti-Bertschy,&nbsp;Julie Clauss,&nbsp;Pierre-Michel Llorca,&nbsp;Isabelle Chereau,&nbsp;Marion Leboyer,&nbsp;Paul Roux,&nbsp;Franck Schürhoff","doi":"10.1080/13546805.2021.2011184","DOIUrl":"https://doi.org/10.1080/13546805.2021.2011184","url":null,"abstract":"<p><strong>Introduction: </strong>Deficits in theory of mind (ToM) can vary depending on the predominant schizophrenia symptoms, and though most neurocognitive functions are involved in ToM, all may not be associated with the same symptoms. With consideration to the relationships between symptoms, neurocognition and ToM, the aim of the present study is to identify the neurocognitive functions influencing ToM capacities according to symptomatic profile.</p><p><strong>Methods: </strong>The study is based on a sample of 124 adults with schizophrenia from a French national cohort. Patients were divided into two groups according to their scores on the five Wallwork factors of the Positive and Negative Syndrome Scale using hierarchical clustering before carrying out multivariable analyses.</p><p><strong>Results: </strong>The \"disorganised group\" (<i>n</i> = 89) showed high scores on the disorganised factor, and had a ToM associated with <i>reasoning</i>, <i>visual recognition</i> and <i>speed of processing</i>. The \"positive group\" (<i>n</i> = 35) showed high scores on the positive and depressive factors, and had a ToM associated with <i>working memory</i>.</p><p><strong>Conclusions: </strong>These results suggest that neurocognitive predictors of ToM in schizophrenia are different according to the predominant clinical dimension, thus refining our knowledge of the relationship between symptoms, neurocognition and ToM, and acknowledging their status as important predictors of patients' functional status.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 1","pages":"49-68"},"PeriodicalIF":1.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39704685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Late-onset obsessive-compulsive disorder as the initial manifestation of possible behavioural variant Alzheimer's disease. 迟发性强迫症作为阿尔茨海默病可能行为变异的初始表现。
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-01-01 Epub Date: 2021-10-29 DOI: 10.1080/13546805.2021.1996342
Massimiliano Ruggeri, Monica Ricci, Carmela Gerace, Carlo Blundo
{"title":"Late-onset obsessive-compulsive disorder as the initial manifestation of possible behavioural variant Alzheimer's disease.","authors":"Massimiliano Ruggeri,&nbsp;Monica Ricci,&nbsp;Carmela Gerace,&nbsp;Carlo Blundo","doi":"10.1080/13546805.2021.1996342","DOIUrl":"https://doi.org/10.1080/13546805.2021.1996342","url":null,"abstract":"<p><strong>Introduction: </strong>A late-onset obsessive-compulsive disorder (OCD) might be a challenging diagnostic issue because of the overlapping with the dementia conditions more related to frontal lobe pathology. We aim to describe and investigate how this condition might represent the isolated long-lasting symptomatology of a frontal Alzheimer's disease (AD).</p><p><strong>Methods: </strong>An elderly woman with normal cognitive status showed a subacute onset of OCD with contamination obsession and washing compulsion. We conducted neuropsychological assessments and neuroimaging examinations at the onset and at 3-years follow-up.</p><p><strong>Results: </strong>At 3-years follow-up, the patient developed cognitive deterioration, frontal behavioural disorders and improvement of OCD. Cognitive assessment showed impairments of executive functions, episodic memory, and constructional apraxia, according to the involvement of fronto-mesial, temporal and parietal regions at neuroimaging. A clinical diagnosis of possible behavioural variant AD was assigned.</p><p><strong>Conclusion: </strong>A typical OCD might be the long-lasting initial manifestation of a possible behavioural variant AD due to dysfunctions of the anterior cingulate network.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 1","pages":"11-19"},"PeriodicalIF":1.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39661591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
What is Capgras delusion? 什么是卡普格拉错觉?
IF 1.7 4区 医学
Cognitive Neuropsychiatry Pub Date : 2022-01-01 Epub Date: 2021-12-10 DOI: 10.1080/13546805.2021.2011185
Max Coltheart, Martin Davies
{"title":"What is Capgras delusion?","authors":"Max Coltheart,&nbsp;Martin Davies","doi":"10.1080/13546805.2021.2011185","DOIUrl":"https://doi.org/10.1080/13546805.2021.2011185","url":null,"abstract":"<p><strong>Introduction: </strong>Capgras delusion is sometimes defined as believing that close relatives have been replaced by strangers. But such replacement beliefs also occur in response to encountering an acquaintance, or the voice of a familiar person, or a pet, or some personal possession. All five scenarios involve believing something familiar has been replaced by something unfamiliar.</p><p><strong>Methods: </strong>We evaluate the proposal that these five kinds of delusional belief should count as subtypes of the same delusion.</p><p><strong>Results: </strong>Personally familiar stimuli activate the sympathetic nervous system (SNS) much more strongly than unfamiliar stimuli. In Capgras delusion, this difference is absent, prompting the delusional idea that a familiar person is actually a stranger. We suggest this absence of an effect of familiarity on SNS response will occur in all five scenarios and will prompt the idea that the familiar has been replaced by the unfamiliar.</p><p><strong>Conclusions: </strong>We propose that: (a) all five scenarios be referred to as subtypes of Capgras delusion; (b) in all five, ideas about replacement are prompted by weakness of SNS responses to familiar stimuli; (c) this is insufficient to generate delusion. For a delusional idea to become a belief, a second factor (impaired hypothesis evaluation) must also be present.</p>","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"27 1","pages":"69-82"},"PeriodicalIF":1.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39824261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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