Cognitive Neuropsychiatry最新文献_第10页

The role of prepotent response inhibition and interference control in depression. 阳性反应抑制和干扰控制在抑郁症中的作用。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-11-01 Epub Date: 2021-10-07 DOI: 10.1080/13546805.2021.1987872

Fan-Fan Li, Xue-Lei Chen, Yu-Ting Zhang, Rui-Ting Li, Xu Li

{"title":"The role of prepotent response inhibition and interference control in depression.","authors":"Fan-Fan Li, Xue-Lei Chen, Yu-Ting Zhang, Rui-Ting Li, Xu Li","doi":"10.1080/13546805.2021.1987872","DOIUrl":"https://doi.org/10.1080/13546805.2021.1987872","url":null,"abstract":"Introduction: The ability to suppress inappropriate prepotent response and to overcome the interference of irrelevant information are two important components of inhibitory control. Little is known, however, about the relevant contributions in these two components of inhibitory control to depression. The aim of the present study was to assess the prepotent response inhibition and interference control simultaneously in a group of patients diagnosed with major depression disorder (MDD).Methods: A clinical group of patients with MDD (n = 41) and a control group of healthy volunteers (n = 39) were recruited and assessed using the stop-signal task and the Flanker task respectively.Results: The results showed longer stop-signal reaction time in patients with MDD in the stop-signal task. Regarding the interference control function, the analysis showed the response accuracy under the incongruent condition was significantly lower in patients with MDD than healthy individuals.Conclusions: In conclusion, patients with MDD showed impairments both in prepotent response inhibition and interference control. The present findings provide a better understanding of the mechanism of depression-related deficits in inhibition and have great implications for the development of cognitive training programmes to remediate cognitive dysfunction in depression.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 6","pages":"441-454"},"PeriodicalIF":1.7,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39495559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

The Relational Trip Task, a novel ecological measure of relational memory: data from a schizophrenia sample. 关系旅行任务，一种新的关系记忆的生态测量:来自精神分裂症样本的数据。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-11-01 Epub Date: 2021-10-11 DOI: 10.1080/13546805.2021.1987870

Ana Elisa Sousa, Gabrielle Pochiet, Jennifer D Ryan, Martin Lepage

{"title":"The Relational Trip Task, a novel ecological measure of relational memory: data from a schizophrenia sample.","authors":"Ana Elisa Sousa, Gabrielle Pochiet, Jennifer D Ryan, Martin Lepage","doi":"10.1080/13546805.2021.1987870","DOIUrl":"https://doi.org/10.1080/13546805.2021.1987870","url":null,"abstract":"Introduction: Relational memory (RM) is severely impaired in schizophrenia. Unitisation can circumvent RM impairments in clinical populations as measured by the transverse-patterning (TP) task, a well-established measure of RM capacity. We compared memory performance on a new ecological RM measure, the Relational Trip Task (RTT), to that of TP at baseline and examined the effects of a unitisation intervention in RTT performance. RTT involves learning relational information of real-life stimuli, such as the relationship between people and places or objects.Methods: TP and RTT performances were examined in 45 individuals with schizophrenia. TP-impaired participants (n = 22) were randomised to either the intervention or an active control group. TP and RTT were administered again after unitisation training. Task validity and reliability were assessed. Intervention group's pre- and post-RTT accuracies were compared and contrasted to that in the control group.Results: RTT and TP were moderately correlated. TP non-learners had inferior performance in RTT at baseline. Improvement in RTT performance after unitisation training was observed in the intervention group; no pre-post improvement was observed in the control group.Conclusion: RTT has an acceptable criterion validity and excellent alternate-form reliability. Unitisation seemed to be successfully generalized to support associations of real-life stimuli.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 6","pages":"421-440"},"PeriodicalIF":1.7,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39506059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The cross-lagged relationship between loneliness, social support, and psychotic-like experiences in young adults. 青年孤独感、社会支持和类精神病经历之间的交叉滞后关系。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-11-01 Epub Date: 2021-07-30 DOI: 10.1080/13546805.2021.1960156

Melody Tan, Emma Barkus, Simone Favelle

{"title":"The cross-lagged relationship between loneliness, social support, and psychotic-like experiences in young adults.","authors":"Melody Tan, Emma Barkus, Simone Favelle","doi":"10.1080/13546805.2021.1960156","DOIUrl":"https://doi.org/10.1080/13546805.2021.1960156","url":null,"abstract":"Background: Individuals with psychotic disorders often report feelings of loneliness, fewer social contacts and less satisfaction with their social support prior to diagnosis. However, temporal relationships between these variables remain unclear. The primary aim of this study was to examine whether subjective and objective social factors predict, or are predicted by, psychotic-like experiences (PLEs) in healthy young adults.Methods: 196 undergraduates completed baseline and 3-month follow-up assessments for PLEs, loneliness, social support size, and satisfaction. Cross-lagged panel models were conducted to investigate the temporal relationships between these variables.Results: Higher loneliness scores, fewer social contacts, and being less satisfied with social support at both time points were significantly associated with higher endorsement of PLEs. Furthermore, after controlling for baseline levels, cross-lagged analyses revealed that individuals who reported feeling more lonely and having less social support at baseline, predicted higher PLEs three months later but not vice versa. No cross-lagged effect was found between the satisfaction of social support and PLEs.Conclusion: The study highlights the significant relationships between loneliness, social support and PLEs. Higher levels of loneliness and smaller social support networks predicted future PLEs. These findings need to be given full consideration in future clinical practice and intervention for young adults with PLEs.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 6","pages":"379-393"},"PeriodicalIF":1.7,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1960156","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39257322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Impaired test performance yet spared neurocognitive functioning in individuals with obsessive-compulsive disorder: the role of performance mediators. 测试成绩受损，但保留神经认知功能的个体强迫症:表现中介的作用。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-11-01 Epub Date: 2021-08-25 DOI: 10.1080/13546805.2021.1967733

Steffen Moritz, Jingyuan Xie, Despina Lion, Danielle Penney, Lena Jelinek

{"title":"Impaired test performance yet spared neurocognitive functioning in individuals with obsessive-compulsive disorder: the role of performance mediators.","authors":"Steffen Moritz, Jingyuan Xie, Despina Lion, Danielle Penney, Lena Jelinek","doi":"10.1080/13546805.2021.1967733","DOIUrl":"https://doi.org/10.1080/13546805.2021.1967733","url":null,"abstract":"Introduction: Although most studies report neurocognitive deficits in patients with obsessive-compulsive disorder (OCD), important exceptions exist, highlighting the possible role of mediators (e.g., poor motivation). This study investigated neurocognitive functioning and potential influences affecting performance in OCD.Methods: Forty-three participants (13 OCD patients, 30 healthy controls) were assessed using a battery of neurocognitive tests. During the assessment, the examiner completed the Impact on Performance Scale (IPS) which measures variables that may impact neurocognitive performance.Results: Pooled neurocognitive performance was lower in OCD patients versus healthy controls at a moderate effect size. Patients performed more poorly on the IPS, particularly the Well-Being During Assessment subscale. Performance differences across the two groups were attenuated to a non-significant small-to-medium effect when the IPS was entered as a covariate. A total of 34% of patients showed scores greater than one standard deviation below the mean compared to 9.63% in healthy individuals. Yet, when a conservative impairment criterion (≥2 standard deviations below the mean) was applied, less than 10% of patients displayed deficits.Conclusions: Neurocognitive impairment in OCD is likely exaggerated. In addition to considering important mediators researchers should report the percentage of participants displaying performance deficits rather than mean group differences alone; the latter obscures the high percentage of patients without impairment and thus may unduly foster stigma in this population.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 6","pages":"394-407"},"PeriodicalIF":1.7,"publicationDate":"2021-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39342858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does comprehensive cognitive remediation improve emotion perception? 综合认知补救是否能改善情绪知觉?

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-09-01 Epub Date: 2021-06-27 DOI: 10.1080/13546805.2021.1946386

Abigail C Wright, Susan R McGurk, Yaniv Shaya, Karin Feldman, Kim T Mueser

{"title":"Does comprehensive cognitive remediation improve emotion perception?","authors":"Abigail C Wright, Susan R McGurk, Yaniv Shaya, Karin Feldman, Kim T Mueser","doi":"10.1080/13546805.2021.1946386","DOIUrl":"https://doi.org/10.1080/13546805.2021.1946386","url":null,"abstract":"Background: Social cognition, including emotion perception, is impaired in people with serious mental illnesses (SMI), and is associated with cognitive and community functioning. Cognitive remediation can improve neurocognition, but the impact on emotion perception has been less well studied. The current study aimed to evaluate the efficacy of a cognitive remediation programme in improving emotion perception.Methods: Thirty-seven people with SMI and a history of difficulties obtaining employment were randomised to either vocational rehabilitation only, or vocational rehabilitation combined with cognitive remediation. Participants were assessed at baseline and post-treatment on a neurocognitive battery, work history, and emotion perception.Results: The cognitive remediation group did not improve more than the vocational rehabilitation only group on either measure of emotion perception, despite significantly greater gains in cognitive functioning. Baseline emotion identification, but not discrimination, was significantly associated with cognition and work history.Conclusions: Despite associations between social and neurocognition, there was no evident transfer of cognitive gains to performance on measures of emotion perception. The findings, though limited by a small sample size, are important in expanding the research indicating that the effects of cognitive remediation tend to be limited to the specific cognitive domains targeted in the program.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 5","pages":"343-356"},"PeriodicalIF":1.7,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1946386","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39114727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Using 360° immersive videos to assess paranoia in a non-clinical population. 使用360°沉浸式视频来评估非临床人群的偏执。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-09-01 Epub Date: 2021-07-21 DOI: 10.1080/13546805.2021.1956885

Clara Della Libera, Etienne Quertemont, Julien Laloyaux, Bénédicte Thonon, Frank Larøi

{"title":"Using 360° immersive videos to assess paranoia in a non-clinical population.","authors":"Clara Della Libera, Etienne Quertemont, Julien Laloyaux, Bénédicte Thonon, Frank Larøi","doi":"10.1080/13546805.2021.1956885","DOIUrl":"https://doi.org/10.1080/13546805.2021.1956885","url":null,"abstract":"Introduction: For the past two decades, virtual reality (VR) has proven to be an innovative approach for the assessment of state paranoia. However, the use of VR remains costly, and avatars are still far from realistic in terms of facial and bodily expressions. The present study aimed to test the validity of three 360° immersive videos (360IVs) as an accessible and realistic alternative for the assessment of non-clinical state paranoia.Method: Three 360IVs were created (a Lift, a Library and a Bar) and included actors behaving naturally. One hundred and fifty healthy students were assessed in terms of their proneness towards trait paranoia, were then exposed to one of the three 360IVs, and finally completed measures of state paranoia, sense of presence and cybersickness.Results: Results revealed the presence of various interpretations about the actor's attitudes in the three 360IVs. Also, paranoid thoughts were predicted by proneness towards trait paranoia in two out of the three 360IVs. Furthermore, moderate levels of sense of presence and low levels of cybersickness were observed for each 360IV.Conclusion: The present study provides evidence in favour of the use of 360IVs as a new accessible, realistic, and standardised tool to assess state paranoia in non-clinical samples.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 5","pages":"357-375"},"PeriodicalIF":1.7,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1956885","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39202380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Faux Pas Recognition Test: transcultural adaptation and evaluation of its psychometric properties in Brazil. 失礼识别测试:巴西的跨文化适应及其心理测量特性评估。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-09-01 Epub Date: 2021-06-16 DOI: 10.1080/13546805.2021.1941830

Rafael Gustavo Sato Watanabe, Andre Enoch Knochenhauer, Miguel Angelo Fabrin, Heloise Helena Siqueira, Hayrã Felipe Martins, Cindi Danielle de Oliveira Mello, Bianca de Lemos Zingano, Mariana Francisco Botelho, Elza Márcia Targas Yacubian, Getulio Rodrigues de Oliveira Filho, Hiago Murilo Melo, Roger Walz, Peter Wolf, Katia Lin

{"title":"Faux Pas Recognition Test: transcultural adaptation and evaluation of its psychometric properties in Brazil.","authors":"Rafael Gustavo Sato Watanabe, Andre Enoch Knochenhauer, Miguel Angelo Fabrin, Heloise Helena Siqueira, Hayrã Felipe Martins, Cindi Danielle de Oliveira Mello, Bianca de Lemos Zingano, Mariana Francisco Botelho, Elza Márcia Targas Yacubian, Getulio Rodrigues de Oliveira Filho, Hiago Murilo Melo, Roger Walz, Peter Wolf, Katia Lin","doi":"10.1080/13546805.2021.1941830","DOIUrl":"https://doi.org/10.1080/13546805.2021.1941830","url":null,"abstract":"Introduction: Many neuropsychiatric and neurodegenerative disorders produce Theory of Mind impairment. We aimed to implement a Brazilian Portuguese version of the Faux Pas Recognition Test (FPRT) and evaluate its psychometric properties.Methods: We first completed an English-Brazilian Portuguese translation and adaptation to obtain an FPRT Brazilian Portuguese version. We performed a multicentric study with 153 healthy participants (68.6% women), mean age of 38.8 years (SD = 14.6) and 12.9 years of schooling (SD = 4.5). Linear regression analysis was performed to evaluate the association of social class, age, schooling, and FPRT scores. The psychometric analyses comprised item analysis, exploratory factor analysis, reliability, and validity analysis.Results: Normative data in a Brazilian population is presented. A positive correlation of scores with years of schooling, social class, and an inverse relation with age was found. The exploratory factorial analysis found a two-component structure, one component, consisting of questions 1 through 6 (Eigenvalue 5.325) and another component, consisting of questions 7 and 8 (Eigenvalue 1.09). Cronbach's alpha of the 20 stories was .72. All control stories had a poor discriminative index.Conclusion: The FPRT Brazilian Portuguese version demonstrated good internal consistency and, psychometric properties and is adequate for use even in lower educational contexts in Brazil.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 5","pages":"321-334"},"PeriodicalIF":1.7,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1941830","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39241029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Imagine that: cholinesterase inhibitor treatment of complex visual hallucinations of unknown aetiology. 想象一下:胆碱酯酶抑制剂治疗病因不明的复杂视幻觉。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-09-01 Epub Date: 2021-06-18 DOI: 10.1080/13546805.2021.1941832

Y Salih, A De Angelis, N A Poole

{"title":"Imagine that: cholinesterase inhibitor treatment of complex visual hallucinations of unknown aetiology.","authors":"Y Salih, A De Angelis, N A Poole","doi":"10.1080/13546805.2021.1941832","DOIUrl":"https://doi.org/10.1080/13546805.2021.1941832","url":null,"abstract":"Introduction: Our objective is to highlight the value of the neurophenomenological classification of complex visual hallucinations (VHs). This approach enabled the authors to successfully treat VHs of uncertain aetiology with cholinesterase inhibitors because the content of the hallucinations suggested dysfunction in cholinergic modulated networks.Methods: We utilise the single case report to describe the nature and content of chronic VHs experienced by a 49-year-old woman following a prolonged admission to ITU. Despite extensive investigation, no clear cause was identified for these hallucinations and the patient did not respond to rationalisation of medications or trials of antipsychotics. We therefore adopted the neurophenomenological approach to classifying and treating her VHs.Results: After several years of distressing visual hallucinations, a course of Rivastigmine was trialed despite no evidence suggestive of a Parkinsonian syndrome. Nevertheless, the patient reported a dose-effect response with significant reduction in the frequency and intensity of her hallucinations, almost to complete resolution.Conclusions: At present there is limited evidence about the medical management of visual hallucinations. This case report suggests that cholinesterase inhibitors may be of benefit, even in the absence of clear parkinsonsian features, if the form and content of the VHs suggest dysfunction in cholinergic modulated attentional networks.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 5","pages":"335-342"},"PeriodicalIF":1.7,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1941832","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39244467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anomalous self-experiences in cognition are negatively associated with neurocognitive functioning in schizophrenia. 认知中的异常自我体验与精神分裂症患者的神经认知功能呈负相关。

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-09-01 Epub Date: 2021-05-31 DOI: 10.1080/13546805.2021.1935225

Christi L Trask, Marina M Matsui, Jonathan R Cohn, Mallory J Klaunig, David C Cicero

{"title":"Anomalous self-experiences in cognition are negatively associated with neurocognitive functioning in schizophrenia.","authors":"Christi L Trask, Marina M Matsui, Jonathan R Cohn, Mallory J Klaunig, David C Cicero","doi":"10.1080/13546805.2021.1935225","DOIUrl":"https://doi.org/10.1080/13546805.2021.1935225","url":null,"abstract":"Introduction: Anomalous self-experiences (ASEs) are disturbances in the subjective experience of the self and are common in people with schizophrenia. Theorists have suggested that ASEs may underlie the neurocognitive deficits that are also common in people with schizophrenia; however, few studies have empirically investigated the relationship between these variables. Thus, the current study aimed to determine whether self-reported ASEs, particularly disturbances in cognitive or mental experiences, are meaningfully related to neurocognitive performance in individuals with schizophrenia.Methods: 48 individuals with schizophrenia and 34 healthy comparison participants completed the Inventory of Psychotic-Like Anomalous Experiences (IPASE), which is composed of five subscales including disturbances in cognition, and the MATRICS Consensus Cognitive Battery (MCCB).Results: Participants with schizophrenia performed worse than controls on each MCCB domain and had higher ASE scores on the total IPASE and all five subscales. Only the IPASE-Cognition subscale was associated with cognitive performance. Specifically, IPASE-Cognition was negatively correlated with scores in attention, visual learning, reasoning, and working memory.Conclusions: These results suggest that self-reported subjective disturbances in cognition may be meaningfully associated with several objectively-measured domains of neurocognition. Severity of ASEs may therefore be an important consideration when analysing the extent of cognitive deficits in schizophrenia.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 5","pages":"307-320"},"PeriodicalIF":1.7,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1935225","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38956866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Cognitive performance and lifetime cannabis use in patients with first-episode schizophrenia spectrum disorder. 首发精神分裂症谱系障碍患者的认知表现和终生大麻使用

IF 1.7 4区医学

Cognitive Neuropsychiatry Pub Date : 2021-07-01 Epub Date: 2021-05-11 DOI: 10.1080/13546805.2021.1924649

M Hájková, K Knížková, A Siroňová, B Keřková, J Jonáš, P Šustová, A Dorazilová, M Rodriguez

{"title":"Cognitive performance and lifetime cannabis use in patients with first-episode schizophrenia spectrum disorder.","authors":"M Hájková, K Knížková, A Siroňová, B Keřková, J Jonáš, P Šustová, A Dorazilová, M Rodriguez","doi":"10.1080/13546805.2021.1924649","DOIUrl":"https://doi.org/10.1080/13546805.2021.1924649","url":null,"abstract":"Introduction: Cognitive impairment is among the core features of schizophrenia. In a healthy population, the cognitive deficit is often linked with cannabis abuse, and although the same would be expected in patients with schizophrenia, research has presented contradictory results.Methods: Participants were patients with first-episode schizophrenia (FES) spectrum disorder who had been lifetime cannabis users (N = 30), FES non-users (N = 53) as well as healthy controls (HC) also divided into cannabis users (N = 20) and non-users (N = 49). All participants underwent an extensive neurocognitive assessment and filled in a cannabis questionnaire, which allowed for a comparison of the four groups on cognitive functioning.Results: FES patients using cannabis showed less impaired cognitive functioning with the most prominent difference in visual memory compared to FES non-users. However, they differed neither in the clinical assessment of general psychopathology, positive and negative symptoms, nor in medication from the patient's non-users. A comparison of the HC who used cannabis, and those who did not, revealed no sizeable differences in cognitive performance between the groups.Conclusions: The results delivered supporting evidence for the trend of superior neurocognitive performance in FES patients with a lifetime history of cannabis use compared to non-using patients.","PeriodicalId":51277,"journal":{"name":"Cognitive Neuropsychiatry","volume":"26 4","pages":"257-272"},"PeriodicalIF":1.7,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/13546805.2021.1924649","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38969692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6