{"title":"Advances in nano-delivery of phytochemicals for glioblastoma treatment","authors":"Melvin Anyasi Ambele, Lorraine Tshegofatso Maebele, Thanyani Victor Mulaudzi, Tsholofelo Kungoane, Botle Precious Damane","doi":"10.1186/s11671-024-04172-9","DOIUrl":"10.1186/s11671-024-04172-9","url":null,"abstract":"<div><p>Glioblastoma (GBM) is an aggressive brain tumor characterized by cellular and molecular diversity. This diversity presents significant challenges for treatment and leads to poor prognosis. Surgery remains the primary treatment of choice for GBMs, but it often results in tumor recurrence due to complex interactions between GBM cells and the peritumoral brain zone. Phytochemicals have shown promising anticancer activity in in-vitro studies and are being investigated as potential treatments for various cancers, including GBM. However, some phytochemicals have failed to translate their efficacy to pre-clinical studies due to limited penetration into the tumor microenvironment, leading to high toxicity. Thus, combining phytochemicals with nanotechnology has emerged as a promising alternative for treating GBM. This review explores the potential of utilizing specific nanoparticles to deliver known anticancer phytochemicals directly to tumor cells. This method has demonstrated potential in overcoming the challenges of the complex GBM microenvironment, including the tight blood–brain barrier while minimizing damage to healthy brain tissue. Therefore, employing this interdisciplinary approach holds significant promise for developing effective phyto-nanomedicines for GBM and improving patient outcomes.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04172-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A comprehensive review on nanoparticle-based photo acoustic: current application and future prospective","authors":"Sebika Panja, Manish Sharma, Harshika Sharma, Abhishek Kumar, Vinay Chandel, Swarup Roy, Deblina Biswas","doi":"10.1186/s11671-024-04173-8","DOIUrl":"10.1186/s11671-024-04173-8","url":null,"abstract":"<div><p>In vivo, molecular imaging is prevalent for biology research and therapeutic practice. Among advanced imaging technologies, photoacoustic (PA) imaging and sensing is gaining interest around the globe due its exciting features like high resolution and good (~ few cm) penetration depth. PA imaging is a recent development in ultrasonic technology that generates acoustic waves by absorbing optical energy. However, poor light penetration through tissue continues to be the key obstacle in the field. The NPs as contrast agents can assist in overcoming tissue penetration depth as NPs can produce high signal to noise (SNR) PA signal which aids reconstruction of high resolution of the PA images in deep tissue sights. Subsequently, NPs are very effective in PA based targeted and precise theranostic applications. This article detail about various NPs (organic, inorganic and hybrid) used in PA imaging and spectroscopy applications including various disease diagnosis, therapy and theranostic. It also features optical property, advantages and limitations of various NPs utilised in PA techniques which would comprehend readers about the potential of NPs in evolving PA technique from laboratory to clinical modality in future.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04173-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilizing nanomaterials for cancer treatment and diagnosis: an overview","authors":"Bageesha Mukhopadhyay, Sudhakar Singh, Avtar Singh","doi":"10.1186/s11671-024-04128-z","DOIUrl":"10.1186/s11671-024-04128-z","url":null,"abstract":"<div><p>Cancer is a deadly disease with complex pathophysiological nature and is the leading cause of death worldwide. Traditional diagnosis methods often detect cancer at a considerably critical stage and the conventional methods of treatment like chemotherapy, radiation therapy, targeted therapy, and immunotherapy have several limitations, multidrug resistance, cytotoxicity, and lack of specificity are a few examples. These pose substantial challenge for effective and favourable cancer treatment. The advent of nanotechnology has revolutionized the face of cancer diagnosis and treatment. Nanoparticles, which have a size range of 1–100 nm, are biocompatible and have special optical, magnetic, and electrical capabilities, less toxic, more stable, exhibit permeability and retention effect, and are used for precise targeting. There are several classes of nanoparticles each having their own sets of unique properties. NPs have played an important role in the drug delivery system, overcoming the multi-drug resistance, reducing the side-effects as seen in conventional therapeutic methods and hence able to solve the limitations of conventional methods of diagnosis and treatment. This review discusses the four major classes of nanoparticles (Lipid based NPs, Carbon NPs and Metallic NPs and Polymeric NPs): their discovery and introduction in medical field, unique properties and characteristics, advantages and disadvantages, sub-categories and characteristics of these categories, major area of application in Cancer diagnosis and treatment, and latest methodologies where these are used in cancer treatment.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04128-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kai Su, Chenxia Tang, Chunyue Li, Shijie Weng, Yong Xiang, Xiaoli Peng
{"title":"Yttrium-doped Li4Ti5O12 nanoparticles as anode for high-rate and high-energy lithium-ion batteries","authors":"Kai Su, Chenxia Tang, Chunyue Li, Shijie Weng, Yong Xiang, Xiaoli Peng","doi":"10.1186/s11671-024-04177-4","DOIUrl":"10.1186/s11671-024-04177-4","url":null,"abstract":"<div><p>Li<sub>4</sub>Ti<sub>5</sub>O<sub>12</sub> (LTO) batteries are known for safety and long lifespan due to zero-strain and stable lattice. However, their low specific capacity and lithium-ion diffusion limit practical use. This study explored modifying LTO through yttrium doping by hydrothermal method to form Li<sub>4</sub>Y<sub>0.2</sub>Ti<sub>4.8</sub>O<sub>12</sub> nanoparticles. This approach optimized electron and ion transport, markedly enhancing rate and cycle performance. XRD and TEM revealed that Y addition increased interplanar distance of LTO and widened Li<sup>+</sup> transport pathways. XPS indicated that Y doping augmented the oxygen vacancy concentration and Ti<sup>3+</sup> content. UV tests demonstrated a band gap reduction from 3.72 eV to 2.94 eV, accompanied by enhanced electronic conductivity. EIS tests showed lithium-ion diffusion coefficient remarkably increased to 1.27 × 10<sup>–10</sup> cm<sup>2</sup> s<sup>−1</sup><sub>.</sub> The initial discharge capacity of Li<sub>4</sub>Y<sub>0.2</sub>Ti<sub>4.8</sub>O<sub>12</sub> at 1 A g<sup>−1</sup> reached 198.9 mAh g<sup>−1</sup> and retained 89.3% capacity after 1000 cycles. At 6 A g<sup>−1</sup>, the discharge capacity was 161.1 mAh g<sup>−1</sup>, while at an ultra-high current density of 20 A g<sup>−1</sup>, it reached 78.8 mAh g<sup>−1</sup>, highlighting its robust rate performance. The yttrium-doped and nano-morphology stabilizes the LTO lattice, enhancing rate performance and cycling stability. This study reveals that LTO has the potential to be used in the high-energy fast-charging storage market.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04177-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Felix E. B. Brettner, Stefanie Gier, Annika Haessler, Jonas Schreiner, Sarah Vogel-Kindgen, Maike Windbergs
{"title":"Anti-inflammatory effects of cyclodextrin nanoparticles enable macrophage repolarization and reduce inflammation","authors":"Felix E. B. Brettner, Stefanie Gier, Annika Haessler, Jonas Schreiner, Sarah Vogel-Kindgen, Maike Windbergs","doi":"10.1186/s11671-024-04175-6","DOIUrl":"10.1186/s11671-024-04175-6","url":null,"abstract":"<div><p>Inflammation plays a critical role in the pathophysiology of many diseases, and dysregulation of the involved signaling cascades often culminates in uncontrollable disease progression and, ultimately, chronic manifestation. Addressing these disorders requires balancing inflammation control while preserving essential immune functions. Cyclodextrins (CDs), particularly β-CD, have gained attention as biocompatible biomaterials with intrinsic anti-inflammatory properties, and chemical modification of their backbone offers a promising strategy to enhance their physicochemical properties, adaptability, and therapeutic potential. This study evaluated and characterized the immunomodulatory effects of amphiphilic CD derivatives, which self-assemble into nanoparticles, compared to soluble parent β-CD. In a human macrophage model, CD nanoparticles demonstrated superior anti-inflammatory activity, with derivative-specific effects tied to their physicochemical properties, surpassing the soluble β-CD control. Alongside the downregulation of key pro-inflammatory markers, significant reductions in inflammasome activation and changes in lipid profiles were observed. The findings of this study underscore the potential of cyclodextrin-based nanoparticles as versatile biomaterials for treating the complex pathophysiology of various acute and chronic inflammation-associated disorders.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04175-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142870418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tumor microenvironment–responsive nanoformulations for breast cancer","authors":"Pallavi Velapure, Divyanshi kansal, Chandrashekhar Bobade","doi":"10.1186/s11671-024-04122-5","DOIUrl":"10.1186/s11671-024-04122-5","url":null,"abstract":"<div><p>Nanomedicine, the most promising approach for regulated and targeted drug delivery, is frequently applied in cancer treatment. Essentially, accumulating evidence indicates that nanomedicine has positive results in the treatment of breast cancer (BC), with many BC patients benefiting from nanomedicine-related treatments. Currently, nanodrug delivery systems based on stimulus responses are gaining popularity because of their additional ability to manage drug release depending on the interior environment of the cancer. This review includes a synopsis of several types of internal (pH, redox, enzyme, reactive oxygen species, and hypoxia) stimuli-responsive nanoparticle drug delivery systems as well as perspectives for forthcoming times. Stimulus-responsive nanoparticles can remain stable under physiological conditions while being rapidly activated to release drugs in response to specific stimuli, prolonging blood circulation and increasing cancer cellular uptake, resulting in excellent therapeutic performance and improved biosafety. In this paper, we discuss tumor microenvironment responsive Nanoformulation for breast cancer treatment.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04122-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142870356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Swastika Tiwari, Shubhra Chaturvedi, Ankur Kaul, Vishakha Choudhary, Philippe Barthélémy, A. K. Mishra
{"title":"Development of amphiphilic self-assembled nucleolipid as BBB targeting probe based on SPECT","authors":"Swastika Tiwari, Shubhra Chaturvedi, Ankur Kaul, Vishakha Choudhary, Philippe Barthélémy, A. K. Mishra","doi":"10.1186/s11671-024-04129-y","DOIUrl":"10.1186/s11671-024-04129-y","url":null,"abstract":"<p>Several approaches have been utilised to deliver therapeutic nanoparticles inside the brain but rendered by certain limitation such as active efflux, non-stability, toxicity of the nanocarrier, transport, physicochemical properties and many more. In this context use of biocompatible nano carriers is currently investigated. We herein present the hypothesis that the nucleoside-lipid based conjugates (nucleolipids) which are biocompatible in nature and have molecular recognition can be tuned for improved permeation across blood–brain barrier (BBB). In this work, a di-C15-palmitoyl-ketal nucleolipid nanoparticle bearing an acyclic chelator has been formulated, radiolabeled with <sup>99m</sup>Tc and evaluated for in vivo fate using SPECT imaging. The mean particle size of particles was 113 nm and found to be nontoxic as depticted through haemolytic assay (2.33% erythrocyte destruction) and 75 ± 0.3% HEK(Human Embryonic Kidney<b>)</b> cells survived at 72 h as depicted in SRB (Sulforhodamine B) toxicity assay. The encapsulation efficiency (68 ± 2.75%) and drug loading capacity (22 ± 1.8%.) was calculated for nanoparticles using Methotrexate as model anti-cancer drug. The mathematical models indicate <i>fickian</i> release with a release constant K<sub>H</sub> = 20.70. With 98 ± 0.75% radiolabelling efficiency and established in vitro stability, nanoparticles showed brain uptake in normal mice as 0.91 times in comparison to BBB compromised mice (1.6% ± 0.03 ID/g)indicating higher brain uptake with rapid clearance as depicted through blood kinetics.</p>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04129-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Olayinka Oluyemi Oluranti, Babatunde Ayodeji Ogundeji, Samuel Bukola Orisajo
{"title":"Comparative impacts of myco-synthesized nanoparticles against strains of Aspergillus spp. causing biodeterioration of stored cocoa beans in Nigeria","authors":"Olayinka Oluyemi Oluranti, Babatunde Ayodeji Ogundeji, Samuel Bukola Orisajo","doi":"10.1186/s11671-024-04113-6","DOIUrl":"10.1186/s11671-024-04113-6","url":null,"abstract":"<div><p>Silver nanoparticle solutions (AgNPs) of some mushrooms: <i>Pleurotus ostreatus</i>, <i>Agaricus bisporus</i> and <i>Agaricus campestris</i> were prepared and characterized using Transmission Electron Microscopy (TEM), Fourier-Transform Infrared (FTIR) spectroscopy, X-Ray Diffraction (XRD) analysis and Energy Dispersive X-ray (EDX) spectroscopy. Each of the myco-sythesized AgNPs was plated against strains of <i>Aspergillus flavus</i> and <i>A. ochraceous,</i> at 5, 10 and 15% concentrations. Colour change from light yellow to orange, yellowish-brown, and reddish brown was observed after overnight incubation (at 28 °C), in the <i>P. ostreatus</i>, <i>A. bisporus,</i> and <i>A. campestris</i> synthesized AgNPs respectively. TEM analysis showed a spherical shape with an average size of 15.25 to 45.85 nm, 9.22 to 52.60 nm and 10.24 to 17.66 nm in <i>P. ostreatus, A. campestris</i> and <i>A. bisporus</i> AgNPs respectively. EDX spectrum showed absorption peaks of silver in the ranges of 0.8–1.4 keV, 6.2–6.6 keV, and 0.8–1.2 keV, and XRD analysis confirmed the crystalline structure of the biosynthesized AgNPs, while FTIR results revealed O–H, N–H, C=O, and C=N as the prominent functional groups. Mycelial inhibitions against <i>A. flavus</i> strains D28AF and D42AF ranged between 43.86–52.73% and 33.83–57.07% respectively, and were not significantly different (P ≤ 0.05) from the standard (copper sulphate). Inhibitions produced against <i>A. ochraceous</i> strains AOD40 and AOD45 ranged between 34.64–52.36% and 37.43–53.56% respectively and also showed similar trend in relation to the standard. This study showed that the myco-synthesized AgNPs were effective against <i>A. flavus</i> and <i>A. ochraceous</i> infecting cocoa beans at storage. They however need to be further improved for future use in the control of cocoa beans pathogens.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04113-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Afshin Pendashteh, Anastasiia Mikhalchan, Tamara Blanco Varela, Juan J. Vilatela
{"title":"Opportunities for nanomaterials in more sustainable aviation","authors":"Afshin Pendashteh, Anastasiia Mikhalchan, Tamara Blanco Varela, Juan J. Vilatela","doi":"10.1186/s11671-024-04087-5","DOIUrl":"10.1186/s11671-024-04087-5","url":null,"abstract":"<div><p>New materials for electrical conductors, energy storage, thermal management, and structural elements are required for increased electrification and non-fossil fuel use in transport. Appropriately assembled as macrostructures, nanomaterials can fill these gaps. Here, we critically review the materials science challenges to bridge the scale between the nanomaterials and the large-area components required for applications. We introduce a helpful classification based on three main macroscopic formats (fillers in a matrix, random sheets or aligned fibres) of high-aspect ratio nanoparticles, and the corresponding range of bulk properties from the commodity polymer to the high-performance fibre range. We review progress over two decades on macroscopic solids of nanomaterials (CNTs, graphene, nanowires, etc<i>.</i>), providing a framework to rationalise the transfer of their molecular-scale properties to the scale of engineering components and discussing strategies that overcome the envelope of current aerospace materials. Macroscopic materials in the form of organised networks of high aspect ratio nanomaterials have higher energy density than regular electrodes, superior mechanical properties to the best carbon fibres, and electrical and thermal conductivity above metals. Discussion on extended electrical properties focuses on nanocarbon-based materials (e.g., doped or metal-hybridised) as power or protective conductors and on conductive nanoinks for integrated conductors. Nanocomposite electrodes are enablers of hybrid/electric propulsion by eliminating electrical transport limitations, stabilising emerging high energy density battery electrodes, through high-power pseudocapacitive nanostructured networks, or downsizing Pt-free catalysts in flying fuel cells. Thermal management required in electrified aircraft calls for nanofluids and loop heat pipes of nanoporous conductors. Semi-industrial interlaminar reinforcement using nanomaterials addresses present structural components. Estimated improvements for mid-range aircraft include > 1 tonne weight reduction, eliminating hundreds of CO<sub>2</sub> tonnes released per year and supporting hybrid/electric propulsion by 2035.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04087-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of blue-light GaN based micro light-emitting diodes using ion implantation technology","authors":"Yu-Hsuan Hsu, Shao-Hua Lin, Dong-Sing Wuu, Ray-Hua Horng","doi":"10.1186/s11671-024-04169-4","DOIUrl":"10.1186/s11671-024-04169-4","url":null,"abstract":"<div><p>This study fabricated 10 μm chip size μLEDs of blue-light GaN based epilayers structure with different mesa processes using dry etching and ion implantation technology. Two ion sources, As and Ar, were applied to implant into the LED structure to achieve material isolation and avoid defects on the mesa sidewall caused by the plasma process. Excellent turn-on behavior was obtained in both ion-implanted samples, which also exhibited lower leakage current compared to the sample fabricated by the dry etching process. Additionally, lower dynamic resistance (R<sub>d</sub>) and series resistance (R<sub>s</sub>) were obtained with Ar implantation, leading to a better wall-plug efficiency of 10.66% in this sample. Consequently, outstanding external quantum efficiency (EQE) values were also present in both implant samples, particularly in the sample implanted with Ar ions. This study proves that reducing defects on the mesa sidewall can further enhance device properties by suppressing non-radiative recombination behavior in small chip size devices. Overall, if implantation is used to replace the traditional dry etching process for mesa fabrication, the ideality factor can decrease from 11.89 to 2.2, and EQE can improve from 8.67 to 11.03%.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04169-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142844679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}