Savitri Tiwari, Reetesh Kumar, Sonia Devi, Prakriti Sharma, Neil Roy Chaudhary, Sushmita Negi, Nikunj Tandel, Srujan Marepally, Sylviane Pied, Rajeev K. Tyagi
{"title":"Biogenically synthesized green silver nanoparticles exhibit antimalarial activity","authors":"Savitri Tiwari, Reetesh Kumar, Sonia Devi, Prakriti Sharma, Neil Roy Chaudhary, Sushmita Negi, Nikunj Tandel, Srujan Marepally, Sylviane Pied, Rajeev K. Tyagi","doi":"10.1186/s11671-024-04098-2","DOIUrl":"10.1186/s11671-024-04098-2","url":null,"abstract":"<div><p>The suboptimal efficacies of existing anti-malarial drugs attributed to the emergence of drug resistance dampen the clinical outcomes. Hence, there is a need for developing novel drug and drug targets. Recently silver nanoparticles (AgNPs) constructed with the leaf extracts of <i>Euphorbia cotinifolia</i> were shown to possess antimalarial activity. Therefore, the synthesized AgNPs from <i>Euphorbia cotinifolia</i> (EcAgNPs) were tested for their parasite clearance activity. We determined the antimalarial activity in the asexual blood stage infection of 3D7 (laboratory strain) <i>P. falciparum</i>. EcAgNPs demonstrated the significant inhibition of parasite growth (EC<sub>50</sub> of 0.75 µg/ml) in the routine in vitro culture of <i>P. falciparum</i>. The synthesized silver nanoparticles were seen to induce apoptosis in <i>P. falciparum</i> through increased reactive oxygen species (ROS) ROS production and activated programmed cell death pathways characterized by the caspase-3 and calpain activity. Also, altered transcriptional regulation of Bax/Bcl-2 ratio indicated the enhanced apoptosis. Moreover, inhibited expression of <i>Pf</i>LPL-1 by EcAgNPs is suggestive of the dysregulated host fatty acid flux via parasite lipid storage. Overall, our findings suggest that EcAgNPs are a non-toxic and targeted antimalarial treatment, and could be a promising therapeutic approach for clearing malaria infection.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aline Aniele Vencato, Naiara Jacinta Clerici, André Luiz Mendes Juchem, Flavio Fonseca Veras, Helena Campos Rolla, Adriano Brandelli
{"title":"Electrospun nanofibers incorporating lactobionic acid as novel active packaging materials: biological activities and toxicological evaluation","authors":"Aline Aniele Vencato, Naiara Jacinta Clerici, André Luiz Mendes Juchem, Flavio Fonseca Veras, Helena Campos Rolla, Adriano Brandelli","doi":"10.1186/s11671-024-04084-8","DOIUrl":"10.1186/s11671-024-04084-8","url":null,"abstract":"<div><p>In this study, lactobionic acid (LBA) was incorporated into poly(vinyl alcohol) (PVA) and poly(ε-caprolactone) (PCL) by electrospinning. The antimicrobial effects of the nanofibers were tested using the agar diffusion method. Only the PVA formulations showed antimicrobial activity against <i>Staphylococcus aureus</i>. The PVA and PCL nanofibers containing LBA showed antioxidant activity ranging from 690.33 to 798.67 µM TEAC when tested by the ABTS method. The characterization of nanofibers was performed by scanning electron microscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis, differential scanning calorimetry, and mechanical analysis. The nanofibers showed a uniform morphology and their average diameters ranged from 295.5 to 2778.2 nm. The LBA addition induced a decrease in the enthalpy of fusion (Δ<i>H</i>m) of PVA and PCL nanofibers, while the Young’s modulus was reduced from 20 to 10 MPa in PCL and PCL-LBA nanofibers, respectively. No relevant differences were observed between the FTIR spectra of the control nanofibers and the nanofibers containing LBA. All nanofibers presented hemolysis rate below 2%, thus can be considered as non-hemolytic materials. Further toxicological assessment was performed with the selected formulation PVA10 + LBA. The evaluations by mutagenicity assay, cell survival measurement, cell viability analysis and agar diffusion cytotoxicity test indicated that there are no significant toxic effects. Electrospun nanofibers PVA-LBA and PCL-LBA were successfully produced, showing good thermal and mechanical properties and non-toxic effects. Furthermore, the nanofibers showed antimicrobial activity and antioxidant activity. The findings of this study indicate that PVA and PCL electrospun nanofibers incorporating LBA are promising for use in packaging applications.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11365877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142115610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Key role of adsorption site abundance in the direct electrochemical co-detection of estradiol and dopamine","authors":"Naela Delmo, Ishan Pande, Emilia Peltola","doi":"10.1186/s11671-024-04092-8","DOIUrl":"10.1186/s11671-024-04092-8","url":null,"abstract":"<p>Estradiol (E2) is a hormone that influences various aspects of women’s health. Beyond its reproductive functions, E2 impacts neurotransmitter systems such as dopamine (DA). Vertically aligned carbon nanofibers (VACNFs) have shown good sensitivity, selectivity against ascorbic acid (AA) and uric acid (UA), biocompatibility, and reduced fouling in DA sensing. In this study, we explore the use of Ti-Ni-CNF electrodes with CNFs grown for 5 min and 30 min for the direct electrochemical co-detection of E2 and DA. The longer growth time led to a 142% increase in average CNF length and a 36% larger electroactive surface area. In E2 detection, the electrodes demonstrate a wide linear range of 0.05–10 µM and sensitivity of 0.016 and 0.020 µA/µM for Ti-Ni-CNF-5 min and Ti-Ni-CNF-30 min, respectively. The sensor performance remains largely unaffected even in the presence of other steroid hormones such as progesterone and testosterone. Co-detection of equimolar E2 and DA shows promising peak separation of 0.34 ± 0.01 V and repeatability after 10 measurements. A notable improvement in the E2/DA peak current ratio, from 0.53 ± 0.07 to 0.81 ± 0.16, was achieved with the increased CNF length. Our results demonstrate the influence of adsorption sites in electrochemical detection, especially for analytes such as E2 and DA that both rely on adsorption for oxidation. While detecting small and fluctuating physiological concentrations remains a challenge, these findings can be used in choosing and fabricating electrode materials for more accurate and accessible continuous hormone measurements, including the possibility of multianalyte sensing platforms.</p>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11358574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MEMS-based meta-emitter with actively tunable radiation power characteristic","authors":"Kunye Li, Yuhao Liang, Yu-Sheng Lin","doi":"10.1186/s11671-024-04088-4","DOIUrl":"10.1186/s11671-024-04088-4","url":null,"abstract":"<div><p>We propose a meta-emitter based on micro-electro-mechanical system (MEMS) technology. The main structure of the meta-emitter unit cell is composed of four symmetrically split crosses of Au and SiO<sub>2</sub> bilayer cantilevers. By changing the size of the cantilevers, this MEMS-based meta-emitter can realize the tunable perfect absorption, and the absorption spectrum is within the longwave infrared (LWIR) wavelength from 8.90 to 11.90 µm. When the surface temperature of the meta-emitter rises, the electrothermal actuation mechanism is performed through the different thermal expansion coefficient (TEC) of the bilayer cantilevers. Therefore, the cantilevers will be bent downward and the bending height of the cantilevers decreases linearly. In such case, the peak value of thermal radiation power can be tuned from the wavelength of 9.52 µm to 10.48 µm when the temperature of meta-emitter is increased from 293 to 1290 K. This proposed MEMS-based meta-emitter is an excellent LWIR light source and has potential application prospects in gas sensing, infrared spectroscopy analysis, medical care and so on.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11344753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142047564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yijoon Kim, Hyangwoo Kim, Kyounghwan Oh, Ju Hong Park, Byoung Don Kong, Chang-Ki Baek
{"title":"Low-energy and tunable LIF neuron using SiGe bandgap-engineered resistive switching transistor","authors":"Yijoon Kim, Hyangwoo Kim, Kyounghwan Oh, Ju Hong Park, Byoung Don Kong, Chang-Ki Baek","doi":"10.1186/s11671-024-04079-5","DOIUrl":"10.1186/s11671-024-04079-5","url":null,"abstract":"<div><p>We have proposed leaky integrate-and-fire (LIF) neuron having low-energy consumption and tunable functionality without external circuit components. Our LIF neuron has a simple configuration consisting of only three components: one bandgap-engineered resistive switching transistor (BE-RST), one capacitor, and one resistor. Here, the crucial point is that BE-RST with a silicon–germanium heterojunction possesses an amplified hysteric current switching with a low latch-up voltage due to improved hole storage capability and impact ionization coefficient. Therefore, the proposed neuron utilizing BE-RST requires an energy consumption of 0.36 pJ/spike, which is approximately six times lower than 2.08 pJ/spike of pure silicon-RST based neuron. In addition, the spiking properties can be tuned by modulating the leakage rate and threshold through gate bias, which contributes to energy-efficient sparse-activity and high learning accuracy. As a result, our proposed neuron can be a promising candidate for executing various spiking neural network applications.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11343930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akshay A. Pawar, Kuldip A. Patil, Dadaso D. Mohite
{"title":"Impact of CuO nanoparticles on the viscosity and vibration damping characteristics of shock absorber oil","authors":"Akshay A. Pawar, Kuldip A. Patil, Dadaso D. Mohite","doi":"10.1186/s11671-024-04080-y","DOIUrl":"10.1186/s11671-024-04080-y","url":null,"abstract":"<div><p>This study investigates the potential of copper oxide (CuO) nanoparticles as additives to enhance the viscosity and vibration-damping characteristics of shock absorber oil. Shock absorbers play a critical role in vehicle safety and handling by mitigating vibrations from road irregularities. However, their effectiveness deteriorates over time. To address this, CuO nanoparticles were explored for their ability to improve lubricant performance. Nano-lubricants were prepared by dispersing CuO nanoparticles at varying concentrations of 0.25 wt%, 0.5 wt%, 1 wt%, and 1.5 wt% in a base oil using ultrasonication. The novelty of this research lies in the innovative use of CuO nanoparticles to significantly enhance the viscosity and vibration-damping properties of shock absorber oil. The viscosity of these nano-lubricants increased significantly, with the 1 wt% CuO nano-lubricant achieving a 20% increase at 25 °C compared to the base oil, indicating improved load-carrying capacity and potential friction reduction. Vibration damping performance was evaluated using a dedicated shock absorber test rig. The nano-lubricants exhibited reduced overall vibration acceleration compared to plain oil, with a 15% improvement in damping effectiveness at the optimal CuO concentration. However, the transmissibility ratio, a key damping metric, did not show significant variation, suggesting that traditional shock absorber designs might require modifications to fully leverage the benefits of CuO nanoparticles. These findings demonstrate the potential of CuO nanoparticles to enhance the viscosity and damping characteristics of shock absorber oil, leading to improved performance at lower temperatures.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11333412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mojeed A. Agoro, Edson L. Meyer, Olufemi I. Olayiwola
{"title":"Assemble of porous heterostructure thin film through CuS passivation for efficient electron transport in dye-sensitized solar cells","authors":"Mojeed A. Agoro, Edson L. Meyer, Olufemi I. Olayiwola","doi":"10.1186/s11671-024-04082-w","DOIUrl":"10.1186/s11671-024-04082-w","url":null,"abstract":"<div><p>Three different modified solar cells have been passivated with copper sulfide (CuS) on a TiO<sub>2</sub> electrode and manganese sulfide (γ‐MnS) hexagonal as photon absorbers. The MnS were prepared using (a-c) <i>bis</i>(<i>N</i>‐Piperl‐<i>N</i>‐<i>p</i>‐anisildithiocarbamato)Manganese(II) Complexes Mn[<i>N</i>-Piper‐<i>N</i>‐<i>p</i>‐Anisdtc] as (MnS_1), <i>N</i>‐<i>p</i>-anisidinyldithiocarbamato Mn[<i>N</i>‐<i>p</i>-anisdtc] as (MnS_2) and <i>N</i>‐piperidinyldithiocarbamato Mn[<i>N</i>‐piperdtc] as (MnS_3). The corresponding passivated films were denoted as CM-1, CM-2, and CM-3. The influence of passivation on the structural, optical, morphological, and photochemical properties of the prepared devices has been investigated. Raman spectra show that the combination of this heterostructure is triggered by the variation in particle size and surface effect, thus resulting in good electronic conductivity. The narrow band gaps could be attributed to good interaction between the passivative materials on the TiO<sub>2</sub> surface. CM-2 cells, stability studies show that the cell is polarized and current flows due to electron migration across the electrolyte and interfaces at this steady state. The cyclic voltammetry (CV) curve for the CM-3 with the highest current density promotes the electrocatalytic activity of the assembled solar cell. The catalytic reactions are further confirmed by the interfacial electron lifetimes in the Bode plots and the impedance spectra. The current–voltage (<i>J–V)</i> analysis suggests that the electrons in the conduction band of TiO<sub>2</sub>/CuS recombine with the semiconductor quantum dots (QDs) and the iodolyte HI-30 electrolyte, resulting in 5.20–6.85% photo-conversions.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11333774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Performance comparison of flip-chip blue-light microLEDs with various passivation","authors":"Yu-Hsuan Hsu, Xin-Dai Lin, Yi-Hsin Lin, Dong-Sing Wuu, Ray-Hua Horng","doi":"10.1186/s11671-024-04078-6","DOIUrl":"10.1186/s11671-024-04078-6","url":null,"abstract":"<div><p>In this study, arrays of μLEDs in four different sizes (5 × 5 μm<sup>2</sup>, 10 × 10 μm<sup>2</sup>, 25 × 25 μm<sup>2</sup>, 50 × 50 μm<sup>2</sup>) were fabricated using a flip-chip bonding process. Two passivation processes were investigated with one involving a single layer of SiO<sub>2</sub> deposited using plasma-enhanced chemical vapor deposition (PECVD) and the other incorporating Al<sub>2</sub>O<sub>3</sub> deposited by atomic layer deposition (ALD) beneath the SiO<sub>2</sub> layer. Owing to superior coverage and protection, the double-layers passivation process resulted in a three-order lower leakage current of μLEDs in the 5 μm chip-sized μLED arrays. Furthermore, higher light output power of μLEDs was observed in each chip-sized μLED array with double layers passivation. Particularly, the highest EQE value 21.9% of μLEDs array with 5 μm × 5 μm chip size was achieved with the double-layers passivation. The EQE value of μLEDs array was improved by 4.4 times by introducing the double-layers passivation as compared with that of μLEDs array with single layer passivation. Finally, more uniform light emission patterns were observed in the μLEDs with 5 μm × 5 μm chip size fabricated by double-layer passivation process using ImageJ software.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11329445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monika Singh, Hari Mohan Sharma, Ram K. Gupta, Anuj Kumar
{"title":"Recent advancements and prospects in noble and non-noble electrocatalysts for materials methanol oxidation reactions","authors":"Monika Singh, Hari Mohan Sharma, Ram K. Gupta, Anuj Kumar","doi":"10.1186/s11671-024-04066-w","DOIUrl":"10.1186/s11671-024-04066-w","url":null,"abstract":"<div><p>The direct methanol fuel cell (DMFC) represents a highly promising alternative power source for small electronics and automobiles due to its low operating temperatures, high efficiency, and energy density. The methanol oxidation process (MOR) constitutes a fundamental chemical reaction occurring at the positive electrode of a DMFC. Pt-based materials serve as widely utilized MOR electrocatalysts in DMFCs. Nevertheless, various challenges, such as sluggish reaction rates, high production costs primarily attributed to the expensive Pt-based catalyst, and the adverse effects of CO poisoning on the Pt catalysts, hinder the commercialization of DMFCs. Consequently, endeavors to identify an alternative catalyst to Pt-based catalysts that mitigate these drawbacks represent a critical focal point of DMFC research. In pursuit of this objective, researchers have developed diverse classes of MOR electrocatalysts, encompassing those derived from noble and non-noble metals. This review paper delves into the fundamental concept of MOR and its operational mechanisms, as well as the latest advancements in electrocatalysts derived from noble and non-noble metals, such as single-atom and molecule catalysts. Moreover, a comprehensive analysis of the constraints and prospects of MOR electrocatalysts, encompassing those based on noble metals and those based on non-noble metals, has been undertaken.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11324629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141984078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Greener healing: sustainable nanotechnology for advanced wound care","authors":"Deepinder Sharda, Komal Attri, Diptiman Choudhury","doi":"10.1186/s11671-024-04061-1","DOIUrl":"10.1186/s11671-024-04061-1","url":null,"abstract":"<div><p>Wound healing involves a carefully regulated sequence of events, encompassing pro-inflammatory and anti-inflammatory stages, tissue regeneration, and remodeling. However, in individuals with diabetes, this process gets disrupted due to dysregulation caused by elevated glucose levels and pro-inflammatory cytokines in the bloodstream. Consequently, the pro-inflammatory stage is prolonged, while the anti-inflammatory phase is delayed, leading to impaired tissue regeneration and remodeling with extended healing time. Furthermore, the increased glucose levels in open wounds create an environment conducive to microbial growth and tissue sepsis, which can escalate to the point of limb amputation. Managing diabetic wounds requires meticulous care and monitoring due to the lack of widely available preventative and therapeutic measures. Existing clinical interventions have limitations, such as slow recovery rates, high costs, and inefficient drug delivery methods. Therefore, exploring alternative avenues to develop effective wound-healing treatments is essential. Nature offers a vast array of resources in the form of secondary metabolites, notably polyphenols, known for their antimicrobial, anti-inflammatory, antioxidant, glucose-regulating, and cell growth-promoting properties. Additionally, nanoparticles synthesized through environmentally friendly methods hold promise for wound healing applications in diabetic and non-diabetic conditions. This review provides a comprehensive discussion and summary of the potential wound-healing abilities of specific natural polyphenols and their nanoparticles. It explores the mechanisms of action underlying their efficacy and presents effective formulations for promoting wound-healing activity.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11322481/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}