Nanoscale Research Letters最新文献

{"title":"Static-spun mesoporous silica-coated CsPbBr3 blue fibres: synthesis and fluorescence properties","authors":"Shengnan Li,&nbsp;Yanrui Yang,&nbsp;Jiahao Song,&nbsp;Xianglin Meng,&nbsp;Cuibing Bai,&nbsp;Biao Wei,&nbsp;Fei Ma,&nbsp;Lin Zhang","doi":"10.1186/s11671-024-04145-y","DOIUrl":"10.1186/s11671-024-04145-y","url":null,"abstract":"<div><p>Due to their excellent properties, blue CsPbBr₃ quantum dots show great promise for full-colour display and lighting applications. This study used acetonitrile, a polar solvent, to post-treat CsPbBr₃ quantum dots, resulting in a blue shift to 453 nm. To enhance stability, these quantum dots were encapsulated within the pore structure of mesoporous silica. A flexible luminescent fiber material was prepared using poly (lactic acid) (PLA) as the substrate, demonstrating improved hydrophobicity and stable optical properties. The material exhibited a contact angle of 99.7° and maintained 82.2% of its fluorescence intensity after 30 days at room temperature. These findings highlight its significant potential for optical applications.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04145-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142600758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospects and challenges of nanomaterials in sustainable food preservation and packaging: a review","authors":"Subrat Kumar","doi":"10.1186/s11671-024-04142-1","DOIUrl":"10.1186/s11671-024-04142-1","url":null,"abstract":"<div><p>Nanomaterials play a pivotal role in food preservation and its safety, offering ingenious solutions for sustainable food packaging. Nanomaterials enable the creation of packaging materials having unique functional properties. It not only extends the shelf life of the foods by releasing preservatives but also enhances food safety by preventing microbial contamination or food spoilage. In this review, we aim to provide an overview of the various applications of nanotechnology in food packaging, highlighting its key advantages. We also delve into the safety considerations and regulatory issues involved in developing nanotechnology-based food packaging materials. Additionally, advancements in the field of nanotechnology-based packaging have the potential to create safer, more sustainable, and high-quality packaging with greater functionality that delivers essential benefits to manufacturers and consumers.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04142-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142600811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Core–shell upconversion nanoparticles with suitable surface modification to overcome endothelial barrier","authors":"Chao Lu,&nbsp;Jianying Ouyang,&nbsp;Jin Zhang","doi":"10.1186/s11671-024-04139-w","DOIUrl":"10.1186/s11671-024-04139-w","url":null,"abstract":"<div><p>Upconversion nanoparticles (UCNPs), capable of converting near-infrared (NIR) light into high-energy emission, hold significant promise for bioimaging applications. However, the presence of tissue barriers poses a challenge to the effective delivery of nanoparticles (NPs) to target organs. In this study, we demonstrate the core–shell UCNPs modified with cationic biopolymer, i.e., N, N-trimethyl chitosan (TMC), can overcome endothelial barriers. The core–shell UCNP is composed of NaGdF₄: Yb³⁺,Tm³⁺ (16.7 ± 2.7 nm) as core materials and silica (SiO₂) shell. The average particle size of UCNPs@SiO₂ is estimated at 26.1 ± 3.7 nm. X-ray diffraction (XRD), transmission electron microscopy (TEM) and element mapping shows the formation of hexagonal crystal structure of β-NaGdF₄ and elements doping. The surface of UCNPs@SiO₂ has been modified with poly(ethylene glycol) (PEG) to enhance water dispersibility and colloidal stability, and further modified with TMC with the zeta potential increasing from -2.1 ± 0.96 mV to 26.9 ± 12.6 mV. No significant toxic effect is imposed to HUVECs when the cells are treated with core–shell UCNPs with surface modification up to 250 µg/mL. The transport ability of the core–shell UCNPs has been evaluated by using the in vitro endothelial barrier model. Transepithelial electrical resistance (TEER) and immunofluorescence staining of tight junction proteins have been employed to verify the integrity of the in vitro endothelial barrier model. The results indicate that the transport percentage of the UCNPs@SiO₂ with PEG and TMC through the model is up to 4.56%, which is twice higher than that of the UCNPs@SiO₂ with PEG but without TMC and six times that of the UCNPs@SiO₂.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04139-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142600757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The two coin sides of bacterial extracellular membrane nanovesicles: atherosclerosis trigger or remedy","authors":"Konstantin A. Lusta,&nbsp;Alexey V. Churov,&nbsp;Dmitry F. Beloyartsev,&nbsp;Alexander L. Golovyuk,&nbsp;Arthur A. Lee,&nbsp;Vasily N. Sukhorukov,&nbsp;Alexander N. Orekhov","doi":"10.1186/s11671-024-04149-8","DOIUrl":"10.1186/s11671-024-04149-8","url":null,"abstract":"<div><p>Among the numerous driving forces that cause the atherosclerotic cardiovascular disease (ASCVD), pathogenic bacterial extracellular membrane nanovesicles (BEMNs) containing toxins and virulence factors appear to be the key trigger of inflammation and atherogenesis, the major processes involved in the pathogenesis of ASCVD. Since BEMNs are the carriers of nanosized biomolecules to distant sites, they are now being considered as a novel drug delivery system. Nowadays, many therapeutic strategies are used to treat ASCVD. However, the conventional anti-atherosclerotic therapies are not effective enough. This primarily due to the inefficiency of non-targeted drug delivery systems to tissue affected areas, which, in turn, leads to numerous side effects, as well as faulty pharmacokinetics. In this regard, nanomedicine methods using nanoparticles (NPs) as targeted drug delivery vehicles proved to be extremely useful. Bioengineered BEMNs equipped with disease-specific ligand moieties and loaded with corresponding drugs represent a promising tool in nanomedicine, which can be used as a novel drug delivery system for a successful therapy of ASCVD. In this review, we outline the involvement of pathogenic BEMNs in the triggering of ASCVD, the conventional therapeutic strategies for the treatment of ASCVD, and the recent trends in nanomedicine using BEMNs and NPs as a vehicle for targeted drug delivery.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04149-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142600789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harnessing curcumin and nanotechnology for enhanced treatment of breast cancer bone metastasis","authors":"Shiva Shakori Poshteh,&nbsp;Shohreh Alipour,&nbsp;Pegah Varamini","doi":"10.1186/s11671-024-04126-1","DOIUrl":"10.1186/s11671-024-04126-1","url":null,"abstract":"<div><p>Breast cancer (BC) bone metastasis poses a significant clinical challenge due to its impact on patient prognosis and quality of life. Curcumin (CUR), a natural polyphenol compound found in turmeric, has shown potential in cancer therapy due to its anti-inflammatory, antioxidant, and anticancer properties. However, its metabolic instability and hydrophobicity have hindered its clinical applications, leading to a short plasma half-life, poor absorption, and low bioavailability. To enhance the drug-like properties of CUR, nanotechnology-based delivery strategies have been employed, utilizing polymeric, lipidic, and inorganic nanoparticles (NPs). These approaches have effectively overcome CUR’s inherent limitations by enhancing its stability and cellular bioavailability both in vitro and in vivo. Moreover, targeting molecules with high selectivity towards bone metastasized breast cancer cells can be used for site specific delivery of curcumin. Alendronate (ALN), a bone-seeking bisphosphonate, is one such moiety with high selectivity towards bone and thus can be effectively used for targeted delivery of curcumin loaded nanocarriers. This review will detail the process of bone metastasis in BC, elucidate the mechanism of action of CUR, and assess the efficacy of nanotechnology-based strategies for CUR delivery. Specifically, it will focus on how these strategies enhance CUR’s stability and improve targeted delivery approaches in the treatment of BC bone metastasis.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04126-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142598889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Superhydrophobic wearable sensor: fabrication, application, and perspective","authors":"Yanan Wang,&nbsp;Wen Cai,&nbsp;Yonghui Zhang,&nbsp;Jiajun Ji,&nbsp;Huanxi Zheng,&nbsp;Defeng Yan,&nbsp;Xin Liu","doi":"10.1186/s11671-024-04138-x","DOIUrl":"10.1186/s11671-024-04138-x","url":null,"abstract":"<div><p>Wearable sensors have attracted considerable interest due to their ability to detect a variety of information generated by human physiological activities through physical and chemical means. The performance of wearable sensors is limited by their stability, and endowing wearable sensors with superhydrophobicity is one of the means to enable them to maintain excellent performance in harsh environments. This review emphasizes the imperative progress in flexible superhydrophobic sensors for wearable devices. Besides, the wettability principle and the mechanism of wearable sensors are briefly introduced to propose the combination of superhydrophobicity and wearable sensors. Next, superhydrophobic substrates for wearable sensors, including but not limited to, polydimethylsiloxane, polyurethane, gel, rubber, and fabric, are described in depth, and also the respective fabrication processes and performances. Moreover, the utility of superhydrophobic wearable sensors in a normal intelligent environment is described, highlighting their application in monitoring physiological signals, such as physical movement, pulse, vibration, temperature, perspiration, respiration, and so on. Finally, this review evaluates the challenges and dilemmas that wearable sensors must be overcome for further development and improve the functional performance of wearable sensors, paving the way for their expansion into advanced wearable sensing systems.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04138-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142595309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paclitaxel loaded Capmul MCM and tristearin based nanostructured lipid carriers (NLCs) for glioblastoma treatment: screening of formulation components by quality by design (QbD) approach","authors":"Pooja Mittal,&nbsp;Madhav Singla,&nbsp; Smriti,&nbsp;Ramit kapoor,&nbsp;Dileep Kumar,&nbsp;Saurabh Gupta,&nbsp;Gaurav Gupta,&nbsp;Tanima Bhattacharya","doi":"10.1186/s11671-024-04132-3","DOIUrl":"10.1186/s11671-024-04132-3","url":null,"abstract":"<div><p>Paclitaxel (PTX), a naturally occurring diterpenoid isolated from Taxus brevifolia, is a first-line drug for the treatment of glioblastoma; however, it suffers from the disadvantages of poor water solubility and nonspecific biodistribution, which cause serious side effects in the human body. The marketed formulation suffers from serious side effects, such as allergic reactions, neutropenia, and neuropathy, which require safe and effective formulations of PTX. In the present study, PTX was entrapped in a solid–liquid lipid mixture with the aid of a surfactant using a modified solvent evaporation technique. Higher entrapment of the impressive stability of the formulation was achieved by employing quality design-based strategies. Optimized levels by employing a numerical optimization technique for each factor, that is, surfactant concentration (X1), lipid concentration (X2), and amount of organic solvent (X3) were 0.3%, 0.76% &amp; 8.3 ml respectively. The resultant formulation exhibited a particle size of 121.44 nm, entrapment efficiency of 94.27%, and zeta potential of −20.21 mV with unimodal size distribution. A reduction in the % crystalline index from 48 to 3.4% ensured the amorphous form of the entrapped drug inside the formulation, which precludes the fear of leakage and instability of the formulation. Cell line studies conducted on U87MG Cell lines also suggested that the NLC of paclitaxel are more effective than those of pure PTX. In summary, PTXNLC seem to be a superior alternative carrier system for the formulation industry to obtain higher entrapment with excellent stability.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04132-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial biosurfactant-mediated green synthesis of zinc oxide nanoparticles (ZnO NPs) and exploring their role in enhancing chickpea and rice seed germination","authors":"Indukalpa Das,&nbsp;Debajit Borah","doi":"10.1186/s11671-024-04134-1","DOIUrl":"10.1186/s11671-024-04134-1","url":null,"abstract":"<div><p>Malnutrition is one of the greatest challenges faced by humanity, which may be addressed by improving crop productivity to ensure food security. However, extensive use of synthetic fertilizers can lead to soil fertility degradation. This study highlights the potential of combining nanotechnology with biotechnology to enhance the germination rates of commercially important crop seeds. Bacterial biosurfactant extracted from a newly isolated <i>Klebsiella</i> sp. strain RGUDBI03 was used as a reducing and capping agent for the synthesis of zinc oxide nanoparticles (ZnO NPs) through a simple method. Extensive characterization of ZnO NPs through electron microscopic analysis showed well-dispersed, homogeneous NPs with a size range of 2–10 nm. High-resolution transmission electron microscopy (HR-TEM) images also revealed molecular fringes of 0.26 nm in single crystal ZnO NPs, with approximately 50% of the NPs exhibiting a size range of 2–4 nm. X-ray diffraction (XRD) results of ZnO NPs indicated the presence of (100), (002), (101), (102), (200), and (112) planes, confirming their crystalline nature. The presence of C = C–H, C = C, C–H, and C = C groups in both the bacterial biosurfactant and ZnO NPs, as depicted by Fourier-transform infrared spectroscopy (FTIR) spectra, confirmed the function of the biosurfactant as a reducing and capping agent. The nano-primed chickpea (<i>Cicer arietinum</i>) and rice (<i>Oryza sativa</i>) seeds showed an increase in water uptake rate, 89% and 92% respectively, compared to the control (73% and 44%), leading to an enhanced germination rate of 98% and 76%, compared to their respective controls (80% and 30%) under optimized conditions. Additionally, the nano-primed seeds exhibited higher levels of α-amylase activity in both seeds (0.37 mg/g for chickpea and 2.49 mg/g for rice) compared to the control. Notably, the ZnO NP priming solution exhibited no cytotoxicity on red blood cells and earthworms (<i>Eudrilus eugeniae</i>), indicating their non-cytotoxic and eco-friendly nature for future field trials.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04134-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Biogenically synthesized green silver nanoparticles exhibit antimalarial activity","authors":"Savitri Tiwari,&nbsp;Reetesh Kumar,&nbsp;Sonia Devi,&nbsp;Prakriti Sharma,&nbsp;Neil Roy Chaudhary,&nbsp;Sushmita Negi,&nbsp;Nikunj Tandel,&nbsp;Srujan Marepally,&nbsp;Sylviane Pied,&nbsp;Rajeev K. Tyagi","doi":"10.1186/s11671-024-04133-2","DOIUrl":"10.1186/s11671-024-04133-2","url":null,"abstract":"","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04133-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142540759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis","authors":"Archna Panghal,&nbsp;S. J. S. Flora","doi":"10.1186/s11671-024-04135-0","DOIUrl":"10.1186/s11671-024-04135-0","url":null,"abstract":"<div><p>Multiple sclerosis (MS) is a neuroimmunological disorder which causes axonal damage, demyelination and paralysis. Although numerous therapeutics have been developed for the effective treatment of MS and a few have been approved in recent decades, complete remission and treatment of MS remain a matter of concern. Nanotechnology is a potential approach for manipulating the properties of materials at the molecular level to attain desired properties. This approach is effective in the treatment of several CNS disorders by enhancing drug delivery, bioavailability and efficacy. We have briefly discussed the neuroimmunological disorders with a particular emphasis on MS. We also explored nanoengineered drug delivery systems, describing several nano-formulations for the treatment of MS, challenges and future of nanotechnology.</p></div>","PeriodicalId":51136,"journal":{"name":"Nanoscale Research Letters","volume":"19 1","pages":""},"PeriodicalIF":5.5,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s11671-024-04135-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}