Self-assembled metal cluster-carbon quantum dot heterostructures with photothermal antibacterial properties

IF 5.5 3区材料科学 Q2 MATERIALS SCIENCE, MULTIDISCIPLINARY

Nanoscale Research Letters Pub Date : 2025-03-31 DOI:10.1186/s11671-025-04243-5

Xulei Yuan, Shaojun Liu, Jun Wang, Jiaqi Liu, Fang Qin, Min Zhang, Jinling Song, Xiang Mao

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引用次数: 0

Abstract

Noble metal (Au, Ag, Cu) cluster is an emerging category of promising interest functions in form of designed constructions. Among various candidates, carbon dots could be treated as one interesting component for synthesis functional candidates while heterogeneous contents are orderly integrated together. In this work, we successfully fabricate heterostructural nanoparticles (HNPs) based on noble metal clusters (Au, Ag and Cu) integrated with carbon quantum dots (CQDs) through self-assembling approach. These HNPs demonstrate remarkable photothermal efficiency, high stability, low hemolysis ratio, excellent biocompatibility and significant bactericidal effects, making them promising candidates for photothermal applications. Notably, the Au–C achieved remarkable photothermal conversion efficiency (PTE) of 54.16% and antibacterial rate over 99%, which also significantly accelerated the healing process in methicillin-resistant Staphylococcus aureus (MRSA)-infected subcutaneous abscess model mice. Our findings highlight the potential of these self-assembled heterostructures, especially Au–C, as effective and promising photothermal agents with antibacterial functionality.

Graphical Abstract

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具有光热抗菌性能的自组装金属团簇-碳量子点异质结构

贵金属（Au, Ag, Cu）簇是以设计结构的形式出现的一类新兴的有前途的兴趣函数。在各种候选物中，碳点可以作为合成功能候选物的一个有趣成分，异质成分有序地整合在一起。在这项工作中，我们通过自组装方法成功地制备了基于贵金属团簇（Au， Ag和Cu）与碳量子点（CQDs）集成的异质结构纳米粒子（HNPs）。这些HNPs具有光热效率高、稳定性好、溶血率低、生物相容性好、杀菌效果显著等特点，具有光热应用前景。值得注意的是，Au-C在耐甲氧西林金黄色葡萄球菌（MRSA）感染的皮下脓肿模型小鼠中光热转换效率（PTE）达到54.16%，抗菌率超过99%，也显著加快了愈合过程。我们的发现强调了这些自组装异质结构的潜力，特别是金-碳，作为具有抗菌功能的有效和有前途的光热剂。图形抽象

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来源期刊

Nanoscale Research Letters 工程技术-材料科学：综合

CiteScore

11.30

自引率

0.00%

发文量

110

审稿时长

48 days

期刊介绍： Nanoscale Research Letters (NRL) provides an interdisciplinary forum for communication of scientific and technological advances in the creation and use of objects at the nanometer scale. NRL is the first nanotechnology journal from a major publisher to be published with Open Access.