Medicinski Glasnik最新文献_第8页

Common inflammatory markers in the screening of knee arthroprosthesis infections. 膝关节假体感染筛查中的常见炎症标志物。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1688-23

Jacopo Conteduca, Marco Filipponi, Paolo Pichierri, Alberto Casto, Luigi Meccariello, Giuseppe Rollo

{"title":"Common inflammatory markers in the screening of knee arthroprosthesis infections.","authors":"Jacopo Conteduca, Marco Filipponi, Paolo Pichierri, Alberto Casto, Luigi Meccariello, Giuseppe Rollo","doi":"10.17392/1688-23","DOIUrl":"https://doi.org/10.17392/1688-23","url":null,"abstract":"Aim To evaluate the sensitivity and specificity of serum C-reactive protein (CRP) in early and late total knee arthroplasty (TKA) infections. Methods Blood tests to determine CRP levels (cut-off 10 mg/L)were conducted before surgery, at 1st day, 7th day and 15th day after surgery and at 1, 3, 6,12, 24 and 36 months. Patients had routine follow-up visits and radiological evaluations at 14 days and at 1, 3, 6, 12, 24 and 36 months. Infections were recorded and classified according to Widmer classification. The χ2 test or Fisher (in subgroups smaller than 10 patients) exact test was used to compare categorical variables. The statistical significance was set at p <0.05. Results A total of 19 infections were diagnosed during the followup. According to Widmer, five were classified as early post-operative and 14 as late chronic. All patients with early infections had suspected symptoms such as fever, swelling and pain. During the first month, 59 patients who had high CRP level but negative microbiological culture were considered as false positive representing a CRP sensitivity of 80% and a specificity of 67.6%. Fourteen patients had late chronic infection. Conclusion This study suggests that a synovial fluid aspiration should be performed in patients with persistent inflammation symptoms with or without radiographic signs of loosening. Moreover, it recommends the use of different serum and synovial tests for periprosthetic joint infection (PJI) diagnosis.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"203-207"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hypoxic mesenchymal stem cells (MSCS)-induced interleukin (IL)-10 alleviate systemic lupus erythematosus (SLE) infl ammation through inhibiting interferon (IFN)-gamma production. 缺氧间充质干细胞（MSCS）诱导的白细胞介素（IL）-10可通过抑制干扰素（IFN）-γ的产生来缓解系统性红斑狼疮（SLE）的炎症。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1608-23

Yan Wisnu Prajoko, Agung Putra, Ardi Prasetio, Nur Dina Amalina

{"title":"Hypoxic mesenchymal stem cells (MSCS)-induced interleukin (IL)-10 alleviate systemic lupus erythematosus (SLE) infl ammation through inhibiting interferon (IFN)-gamma production.","authors":"Yan Wisnu Prajoko, Agung Putra, Ardi Prasetio, Nur Dina Amalina","doi":"10.17392/1608-23","DOIUrl":"https://doi.org/10.17392/1608-23","url":null,"abstract":"Aim To determine the eff ect of hypoxic mesenchymal stem cells (MSCs) on the interleukin (IL)-10 and interferon (IFN)-gamma in peripheral blood mononuclear cells (PBMCs) from systemic lupus erythematosus (SLE) patients. Methods This study used a post-test control group design. Hypoxic MSCs were isolated and characterized according to their surface marker expression and diff erentiation capacities. PBMCs isolated from SLE patients were divided into three groups: control and two treatment groups. The treatment groups were treated by co-culturing MSCs to PBMCs with a ratio of 1:10 (T1) and 1:1 (T2) for 48 h incubation. Furthermore, IFN-gamma and IL-10 levels were determined by cytometric bead array (CBA) fl ow cytometry. Results Hypoxic MSCs signifi cantly decreased the IFN-gamma levels and increased the IL-10 levels in dose-dependent manner compared to the control group. The highest activity of hypoxic MSCs was noticed in T2 group. Conclusion Hypoxic MSCs- induced IL-10 are important in the control of anti-infl ammatory eff ect on SLE through inhibiting IFN-gamma.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Renal function in patients with chronic hepatitis B during antiviral therapy. 抗病毒治疗期间慢性乙型肝炎患者的肾功能。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1617-23

Nerma Čustović, Lejla Alić, Ismar Rašić, Aida Saray, Amila Mehmedović, Nadža Zubčević

{"title":"Renal function in patients with chronic hepatitis B during antiviral therapy.","authors":"Nerma Čustović, Lejla Alić, Ismar Rašić, Aida Saray, Amila Mehmedović, Nadža Zubčević","doi":"10.17392/1617-23","DOIUrl":"https://doi.org/10.17392/1617-23","url":null,"abstract":"Aim To analyse the impact of the length of antiviral therapy with tenofovir disoproxil fumarate (TDF) on the renal function in patients with chronic hepatitis B (CHB). Methods A cross-sectional study included 75 patients with CHB treated with tenofovir, who had a normal renal function at the beginning of the treatment. Renal function was determined based on glomerular filtration rate (eGFR) value using the Modification of Diet in Renal Disease formula (MDRD). Measurement of serum creatinine concentration and urinary protein excretion were performed using standard laboratory analyses. Viral load quantification (HBV-DNA) was determined by polymerase chain reaction (PCR). The degree of liver fibrosis was determined using fibrosis4 (FIB-4) and aspartate transaminase to platelet ratio index (APRI) fibrosis score. Results Out of 75 CHB patients, 37 were on antiviral treatment for up to 2 years (group 1) and 38 patients on antiviral treatment longer than two years (group 2). Mean age of patients was not significantly different between the groups (p=0.076), nor was the gender distribution. There was no statistically significant difference between the mean values of the eGFR in the two groups (91.89±9.24 vs. 88.42±7.84 mL/min/1.73m2; p=0.42), as well as between the mean values of serum creatinine (p=0.360) and 24-hour urine protein excretion (p=0.380). There was no statistically significant correlation between renal parameters and viral load, APRI and FIB-4 fibrosis score. Conclusion Results of our study did not show significant changes in the measured parameters of renal function in group 1 and group 2 of patients, regardless of the length of antiviral treatment, indicating a good renal safety profile of TDF.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"78-84"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139716654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single-centre experience with the treatment of high-prevalence metabolic syndrome in kidney transplant patients in Bosnia and Herzegovina. 波斯尼亚和黑塞哥维那肾移植患者高发代谢综合征的单中心治疗经验。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1665-23

Maida Dugonjić-Taletović, Denijal Tulumović, Mirna Alečković-Halilović, Mirha Pjanić, Mithad Hajder, Alma Halilčević-Terzić, Danijela Lončar, Amila Jašarević

{"title":"Single-centre experience with the treatment of high-prevalence metabolic syndrome in kidney transplant patients in Bosnia and Herzegovina.","authors":"Maida Dugonjić-Taletović, Denijal Tulumović, Mirna Alečković-Halilović, Mirha Pjanić, Mithad Hajder, Alma Halilčević-Terzić, Danijela Lončar, Amila Jašarević","doi":"10.17392/1665-23","DOIUrl":"https://doi.org/10.17392/1665-23","url":null,"abstract":"Aim To analyse prevalence of metabolic syndrome (MS) in kidney transplant recipients at the University Clinical Centre Tuzla in Bosnia and Herzegovina (B&H), and determine effects of a modern drug therapy in achieving target metabolic control in kidney transplant patients. Methods A single-centre prospective study that included 142 kidney transplant patients over one year follow-up period was conducted. Patient data were collected during post-transplant periodical controls every 3 months including data from medical records, clinical examinations and laboratory analyses. Results Out of 142 kidney transplant patients, MS was verified in 85 (59.86%); after a pharmacologic treatment MS frequency was decreased to 75 (52.81%). After a one-year period during which patients were receiving therapy for MS, a decrease in the number of patients with hyperlipoproteinemia, decrease in average body mass index (BMI), glycemia and haemoglobin A1C (HbA1C) were observed. Hypertension did not improve during this period, which can be explained by transplant risk factors in the form of immunosuppressive drugs and chronic graft dysfunction. Conclusion A significant reduction in components of the metabolic syndrome after only one year of treatment was recorded, which should be the standard care of kidney transplant patients.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"85-90"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139716655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breaking habits: safety and efficacy of elective electrocardioversion of atrial fibrillation and atrial flutter in the setting of day hospital. 打破习惯：日间医院心房颤动和心房扑动电复律的安全性和有效性。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1640-23

Ammar Brkić, Minela Bećirović, Emir Bećirović, Tarik Brkić, Esad Brkić, Denis Mršić, Amir Bećirović, Amila Jašarević, Emir Softić, Alma Mujić Ibralić

{"title":"Breaking habits: safety and efficacy of elective electrocardioversion of atrial fibrillation and atrial flutter in the setting of day hospital.","authors":"Ammar Brkić, Minela Bećirović, Emir Bećirović, Tarik Brkić, Esad Brkić, Denis Mršić, Amir Bećirović, Amila Jašarević, Emir Softić, Alma Mujić Ibralić","doi":"10.17392/1640-23","DOIUrl":"https://doi.org/10.17392/1640-23","url":null,"abstract":"Aim To examine safety and efficiency of electrocardioversion (EC) in elective treatment of atrial fibrillation and atrial flutter in the setting of Day Hospital by determining success rate, frequency of adverse events and possible cost benefit compared to admitting a patient into hospital. Methods This prospective observational cohort study was performed in Day Hospital and in Intensive Care Department of Internal Medicine Clinic, University Clinical Centre Tuzla from January 2019 to December 2022 and included 98 patients with a persistent form of atrial fibrillation (AF) or atrial flutter. The patients who were divided in two groups, 56 hospitalized and 42 patients accessed in Day Hospital. In all patients, medical history, physical examination, electrocardiogram (ECG) and transthoracic echocardiogram (TTE) evaluation was performed in addition to laboratory findings. Electrocardioversion was performed with a monophasic General Electric defibrillator in anterolateral electrode position with up to three repetitive shocks. Results In hospital setting group overall succes rate of electrocardioversion was 85%, with average 2.1 EC attemps, there was with one fatal outcome due to stroke, one case of ventricular fibrillation (VF) due to human error, and 6 minor adverse events; with average cost of was 1408.70 KM (720.23 €) per patient. In Day Hospital setting succes rate was 88%, with average 2 EC attempts, no major adverse events, 8 minor adverse events; and average cost was of 127.23 KM (65.05 €) per patient. Conclusion Performing elective electrocardioversion in Day Hospital setting is as safe as admitting patients into hospital but substantially more cost effective.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early career accuracy of shoulder ultrasound in evaluating rotator cuff tendon tears. 肩部超声波评估肩袖肌腱撕裂的早期准确性。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1702-23

Naser Obeidat, Asma'a Al-Mnayyis, Suhaib Bani Essa, Mohammad Alkhatatba, Heba Al Qudah, Majed M Aljarrah, Yahya Alshgerat, Ammar Al-Tawarh, Raghad Al-Titi, Taqwa Alzuqaili, Waseem Samir

{"title":"Early career accuracy of shoulder ultrasound in evaluating rotator cuff tendon tears.","authors":"Naser Obeidat, Asma'a Al-Mnayyis, Suhaib Bani Essa, Mohammad Alkhatatba, Heba Al Qudah, Majed M Aljarrah, Yahya Alshgerat, Ammar Al-Tawarh, Raghad Al-Titi, Taqwa Alzuqaili, Waseem Samir","doi":"10.17392/1702-23","DOIUrl":"https://doi.org/10.17392/1702-23","url":null,"abstract":"Aim To compare the accuracy of shoulder ultrasound (US) in diagnosing rotator cuff tendon tears between junior and experienced musculoskeletal (MSK) radiologists. Also, to compare the overall ultrasound accuracy referenced to MRI. Methods A retrospective data collection for patients with clinically suspected rotator cuff tears who underwent ultrasound from June 2021 - June 2023 was conducted. Patients who also performed MRI for the same shoulder were only included in the study. US and MRI images were evaluated by two MSK radiologists with different experience levels. The diagnosis of rotator cuff tears was done on MRI through consensus. Ultrasound accuracy referenced to MRI was calculated for each radiologist. A second consensus was conducted for US images to calculate the overall US accuracy. The percentage of agreement and Cohen's kappa correlation coefficient were calculated before and after the US consensus. Results Forty-one patients were included in the study, 12 (29.3%) males and 29 (70.7%) females, with a mean age of 49.6 years. Sensitivity, specificity, positive (PPV) and negative predictive values (NPV), and accuracy of US interpreted by junior vs experienced MSK radiologists for supraspinatus full thickness tears (FTTs) were 100% vs 91%, 90% vs 93%, 79% vs 83%, 100% vs 97%, and 93% vs 93%, respectively. After the second consensus, sensitivity, specificity, PPV and NPV, and accuracy were 91%, 90%, 77%, 96%, and 90%, respectively. Conclusion The accuracy of shoulder ultrasound in diagnosing supraspinatus FTTs by junior MSK radiologists compares well to the more experienced ones, but not for partial thickness tears (PTTs).","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"190-195"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The ion resonance and bromelain-vitamin C vs bromelainvitamin C to prevent ankle complications in post-operative bimalleolar surgery. 离子共振和溴麦角维他命 C 与溴麦角维他命 C 预防双侧踝关节术后并发症的对比。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1691-23

Luigi Meccariello, Anna Iolanda Bello, Giovanni Bove, Nicola Gagliardo, D'Anna Raffaele, Luigi Matera

{"title":"The ion resonance and bromelain-vitamin C vs bromelainvitamin C to prevent ankle complications in post-operative bimalleolar surgery.","authors":"Luigi Meccariello, Anna Iolanda Bello, Giovanni Bove, Nicola Gagliardo, D'Anna Raffaele, Luigi Matera","doi":"10.17392/1691-23","DOIUrl":"https://doi.org/10.17392/1691-23","url":null,"abstract":"Aim To investigate whether the use of ion resonance and bromelain-vitamin C or bromelain-vitamin C is the best to prevent ankle complications in post operative bimalleolar surgery. Methods A total of 61 patients treated with bimalleolar surgery were enrolled. The patients were divided into three groups: the first group (n=22) treated only with the surgery, the second group (n=18) treated by ion resonance and bromelain-vitamin C, and the third group (n=21) was treated with bromelain-vitamin C. All patients in the second and third group underwent adjuvant therapy for 50 days. The criteria to evaluate the three groups during the clinical and radiological follow-up were as follows: complications and soft tissue status. Bone healing measured by the Radiographic Union Score Ankle (RUSA), and functional results were evaluated according to the American Foot & Ankle Score (AFAS). Results In the first group nine (out of 22; 40.90%) patients developed complications, in the second group three (out of 18; 16.67%) and in the third group seven (out of 21; 33.33%) presented complications. There is no statistical difference between the three groups regarding the type of fractures, mean age, gender ratio. The worst radiographic and stiffness results in the first group were found (p=0.006). The second group showed better bone healing (p=0.049), better performance in functional recovery measured by AFAS (p=0.039). Conclusion Ion resonance and bromelain-vitamin C group showed better outcomes to improve the functional outcome; it allows reduction of complications, consequently, an early return to quality life, and a corresponding improvement of the quality of life.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"236-243"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139716657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of age at menopause and age at menarche with later-life skeletal fragility fractures in Bosnian postmenopausal women. 波斯尼亚绝经后妇女绝经年龄和初潮年龄与晚年骨骼脆性骨折的关系。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1692-23

Amila Kapetanović, Gordan Bajić, Sabina Sarić, Rubina Alimanović-Alagić, Martina Bonić, Dženan Pleho

{"title":"Association of age at menopause and age at menarche with later-life skeletal fragility fractures in Bosnian postmenopausal women.","authors":"Amila Kapetanović, Gordan Bajić, Sabina Sarić, Rubina Alimanović-Alagić, Martina Bonić, Dženan Pleho","doi":"10.17392/1692-23","DOIUrl":"https://doi.org/10.17392/1692-23","url":null,"abstract":"Aim To investigate the effects of estrogen-related events (age at menopause, age at menarche) on later-life skeletal fragility in Bosnian postmenopausal women. Methods A total of 100 postmenopausal Bosnian women, aged between 55 and 75 years, were included. The women in the study group (n=50) had fragility fractures, and in the control group (n=50) were without fragility fractures. Bone mineral density (BMD) was measured using Dual Energy X-ray Absorptiometry (DXA) on the lumbar spine (L2-L4) and proximal femur. Results No statistically significant difference relating to the age between the groups was found. The average age at menopause was 44.70 years in women with fragility fractures and 51.76 years in women without fragility fracture (p=0.0001). The average age at menarche was 14.30 years in women with fragility fractures and 13.70 years in women without fragility fractures (p=0.140). T score of ≤-2.5 SD was found in 40 (80%) women in the study group, and in eight (16%) women in the control group (p=0.0001). Conclusions Age at menopause, but not age at menarche, was risk factors for later-life fragility fracture in postmenopausal Bosnian women. In addition, fragility fractures correlated with low BMD in this population group.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"154-158"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139718038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative assessment of high-risk cardiovascular medication knowledge between practising and student nurses: a descriptive multi-centre study. 执业护士和在校护士对高危心血管药物知识的比较评估：一项描述性多中心研究。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1659-23

Najla Taslim, Amal Turikham Alghamdi, Dana Ali Alqarni, Shaista Rashid, Dustin Todd Edge

{"title":"Comparative assessment of high-risk cardiovascular medication knowledge between practising and student nurses: a descriptive multi-centre study.","authors":"Najla Taslim, Amal Turikham Alghamdi, Dana Ali Alqarni, Shaista Rashid, Dustin Todd Edge","doi":"10.17392/1659-23","DOIUrl":"https://doi.org/10.17392/1659-23","url":null,"abstract":"Aim To examine unexplored knowledge of cardiovascular highrisk medications and perception thereof among practising nurses and students in the Kingdom of Saudi Arabia (KSA). Methods The multicentre cross-sectional quantitative study used an online survey dichotomised into a knowledge test (true/false and multiple choice questions) and a perception assessment (closed-ended questions). Four hundred and eighteen nurses participated in the study. Results In the knowledge test, 19 (4.5%) participants scored high (≥71%), while 83 (19.8%) and 316 (75.5%) demonstrated moderate (score ≥51-70%) and poor performance (score ≤50%), respectively. In a comparative analysis, the knowledge level of staff nurses was significantly higher than the students but not the other nurses' cohort. Nurses' specialty and region of KSA were strongly associated with the knowledge level. Emergency room nurses and those belonging to the eastern region of KSA exhibited higher knowledge levels than other subgroups. A vast majority of nurses, 128 (30.6 %), rated their knowledge of medicines as somewhat sufficient, while quoting insufficient knowledge 226 (54.1%) as the major cause of medication errors. Three hundred and sixteen (75%) nurses expressed interest in undergoing specialised training in high-alert medication-based therapy preferably in a classroom setting by 279 (66.7%). Conclusion This study revealed a marked knowledge deficit in high-risk cardiovascular drugs among nurses. The pharmacological curriculum in nursing schools should be tailored to be clinically oriented and reinforced with problem-based learning. Continued pharmacology education focusing on high-risk drugs should be implemented among nurses to safeguard patient lives by mitigating the risks of medication error.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"166-174"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139716649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison between conventional open-heart valve surgery and minimally invasive valve replacement surgery regarding the length of hospital stay and usage of blood derivates: insights from a single-centre, single-surgeon study conducted in Bosnia and Herzegovina. 传统开胸瓣膜手术与微创瓣膜置换手术在住院时间和血液衍生物用量方面的比较：在波斯尼亚和黑塞哥维那进行的单中心、单外科医生研究的启示。

Medicinski Glasnik Pub Date : 2024-02-01 DOI: 10.17392/1670-23

Nermir Granov, Amel Hadžimehmedagić, Armin Šljivo, Tarik Selimović, Damir Kurtagić, Edin Kabil, Muhamed Djedović, Arian Abdulkhaliq

{"title":"Comparison between conventional open-heart valve surgery and minimally invasive valve replacement surgery regarding the length of hospital stay and usage of blood derivates: insights from a single-centre, single-surgeon study conducted in Bosnia and Herzegovina.","authors":"Nermir Granov, Amel Hadžimehmedagić, Armin Šljivo, Tarik Selimović, Damir Kurtagić, Edin Kabil, Muhamed Djedović, Arian Abdulkhaliq","doi":"10.17392/1670-23","DOIUrl":"https://doi.org/10.17392/1670-23","url":null,"abstract":"Aim To analyse the correlation between different surgical methodologies employed in valve diseases treatment and their subsequent impact on the duration of hospitalization. Methods This retrospective study conducted at the Clinical Centre of the University of Sarajevo analysed medical records of 163 valve disease patients treated between January 2019 and November 2022. The patients were divided into two groups: 77 had openheart valve surgery and 86 underwent minimally invasive cardiac surgery (MICS). Results The mean duration of the surgical procedures was 3.9±1.3 hours, with conventional open-heart surgery requiring an average of 3.6±1.1 hours and minimally invasive cardiac surgery (MICS) procedure 4.2±1.5 hours. No substantial disparities were found in the total length of hospitalization between the two groups, as both conventional (8.2±4.5 days) and MICS (8.7±7.0 days) demonstrated similar duration. Similarly, the total duration of intensive care unit (ICU) stay displayed similarity, with conventional surgery patients staying an average of 3.9±2.8 days and MICS patients of 4.2±4.1 days. The pattern of blood transfusion and fresh-frozen plasma usage revealed higher rates in the conventional valve surgery group comparing to the MICS group. Conclusion Minimally invasive valve surgery, despite slightly longer operative times, resulted in lower blood transfusion requirements and comparable hospitalization and ICU stay.","PeriodicalId":51129,"journal":{"name":"Medicinski Glasnik","volume":"21 1","pages":"91-97"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139716650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0