Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques最新文献

{"title":"Conservative Management of Hypopharyngeal Perforation: A Rare Iatrogenic Complication of Transesophageal Echocardiography","authors":"Yafeng Guo,&nbsp;Zhaokun Ma,&nbsp;Hongxu Chen,&nbsp;Hua Yan","doi":"10.1111/echo.70372","DOIUrl":"10.1111/echo.70372","url":null,"abstract":"<p>This case highlights a rare but life-threatening complication of TEE—hypopharyngeal perforation. Blind probing when encountering resistance is a critical avoidable risk factor. Early recognition of symptoms and prompt diagnosis enable successful conservative management in select patients.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 2","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146114947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are We Ready to Monitor the Atrium? From Ventricular-Centric to Chamber-Integrated Cardiotoxicity Surveillance: The Emerging Role of Left Atrial Strain","authors":"Cristina Madaudo,&nbsp;Daniela Di Lisi,&nbsp;Giuseppina Novo","doi":"10.1111/echo.70394","DOIUrl":"10.1111/echo.70394","url":null,"abstract":"&lt;p&gt;Patients with diffuse large B-cell lymphoma (DLBCL) treated with the R-CHOP chemotherapy regimen represent a population at substantial risk of cancer therapy–related cardiac dysfunction (CTRCD) [&lt;span&gt;1, 2&lt;/span&gt;]. Nearly 29% of patients developed a reduction in left ventricular systolic function during active treatment, highlighting cardiotoxicity as an early and clinically relevant complication of rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) therapy [&lt;span&gt;3&lt;/span&gt;]. Traditionally, left ventricular ejection fraction (LVEF) has served as the sole echocardiographic criterion for diagnosing CTRCD [&lt;span&gt;4&lt;/span&gt;]. More recently, the 2022 ESC Cardio-Oncology Guidelines introduced left ventricular global longitudinal strain (LV-GLS) as an additional primary diagnostic parameter, acknowledging the limitations of LVEF in detecting early myocardial injury [&lt;span&gt;1&lt;/span&gt;]. However, both indices primarily focus on ventricular systolic mechanics and may overlook early diastolic and left atrial (LA) involvement. This observation provides a strong rationale for refining cardiovascular monitoring strategies beyond conventional parameters. Most of the available evidence on LA function during cardiotoxic treatments originates from studies in breast cancer populations, resulting in heterogeneous conclusions [&lt;span&gt;5, 6&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;In this context, the study by Wang provides timely and clinically relevant insights into the role of LA function assessed by speckle-tracking echocardiography (STE) in patients with DLBCL treated with R-CHOP chemotherapy, shifting attention toward a chamber that plays a central role in cardiovascular hemodynamics and disease progression [&lt;span&gt;7&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Assessment of LA phasic function has the potential to improve both the diagnostic accuracy and prognostic relevance of diastolic dysfunction and heart failure (HF), particularly heart failure with preserved ejection fraction (HFpEF) [&lt;span&gt;8&lt;/span&gt;]. Left ventricular diastolic dysfunction generally precedes systolic dysfunction across a wide range of clinical settings and has been consistently established as an independent predictor of all-cause mortality with a 3.53-fold increased risk of cardiovascular events or death [&lt;span&gt;9&lt;/span&gt;]. Within this framework, LA strain, especially reservoir strain (LASr), acts as an integrated marker of chronic filling pressure elevation, myocardial stiffness, and impaired ventricular–atrial coupling [&lt;span&gt;10&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;The authors demonstrate a significant deterioration of LA strain parameters following R-CHOP therapy, even in patients without overt systolic impairment. This finding reinforces the concept that atrial dysfunction may represent one of the earliest manifestations of CTRCD, preceding changes in LVEF and potentially even LV-GLS [&lt;span&gt;7&lt;/span&gt;]. Notably, the authors provide robust validation of this approach by demonstrating that an LASr &gt;35% cut-off showed substantial agreement with","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 2","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70394","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146087862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetal RFOF Mimics CoA: The Predictive and Differential Value of Cardiac Output and Left Heart Morphological Parameters","authors":"Qin Lin,&nbsp;Kexuan Liu,&nbsp;Pan Yang,&nbsp;Jiangli Dong,&nbsp;Shi Zeng,&nbsp;Zhu Ouyang,&nbsp;Ming Zhang,&nbsp;Ganqiong Xu","doi":"10.1111/echo.70399","DOIUrl":"10.1111/echo.70399","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Studies have confirmed that a RFOF (redundant foramen ovale flap) can mimic CoA (coarctation of the aorta) in terms of traditional indicators; however, there is currently no more comprehensive and feasible indicator to differentiate between the two. This study aims to investigate the effect of RFOF on cardiac output, and explore the ability of multiple left cardiac parameters to differentiate RFOF from CoA.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This prospective diagnostic cohort study consecutively enrolled fetuses with suspected CoA and normal controls. Comprehensive echocardiographic measurements, including cardiac output and novel morphological parameters—including RCO/LCO (right cardiac output/left cardiac output), the FOFd/LAd (foramen ovale flap/left atrial diameter ratio), aortic arch angle, and LIOA (left ventricular inflow-outflow tract angle)—were performed by operators blinded to the postnatal outcome. ROC (Receiver operating characteristic) curve analysis was performed to evaluate the predictive ability of all indicators for pregnancy outcomes.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Analysis revealed that in the RFOF Group, FOFd/LAd had the highest AUC (area under the curve), followed by RCO/LCO. In the CoA Group, the aortic isthmus/ductus arteriosus diameter (Aoi/DA) and aortic arch angle showed the highest AUC values.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusion&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;RFOF can mimic the ultrasonic manifestations of CoA in terms of traditional indicators. FOFd/LAd &gt; 0.65 (AUC = 1.000) is identified as a specific marker for RFOF, while RCO/LCO &gt; 1.60 (AUC = 0.966) provides strong supportive evidence. Conversely, an aortic arch angle &gt; 75.84° receiver operating characteristic (AUC = 0.995) combined with Aoi/DA &lt; 0.75 (AUC = 0.999), suggests a higher probability of CoA. FOFd/LAd, aortic arch angle, and LIOA can help distinguish between RFOF and CoA.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Summary&lt;/h3&gt;\u0000 \u0000 &lt;div&gt;\u0000 &lt;ul&gt;\u0000 \u0000 &lt;li&gt;\u0000 &lt;p&gt;&lt;b&gt;What's already known about this topic?&lt;/b&gt;&lt;/p&gt;\u0000 \u0000 &lt;p&gt;The established consensus indicates that RFOF can mimic the sonographic features of CoA prenatally by causing imbalances in traditional parameters of cardiac chamber dimensions and great vessel diameter ratios. However, reliable tools for prenatally distinguishing between these two conditions based on hemodynamic and left heart morphological characteristics remain unavailable.&lt;/p&gt;\u0000 &lt;/li&gt;","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146068385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Value of Three-Dimensional Speckle Tracking Echocardiography in the Estimation of Left Ventricular Systolic Function in Patients With Coronary Microvascular Dysfunction","authors":"Wenqing Hui,&nbsp;Xiaofeng Qian,&nbsp;Yutong Liu,&nbsp;Ziyan Wang,&nbsp;Jing Dong,&nbsp;Pingyang Zhang","doi":"10.1111/echo.70398","DOIUrl":"10.1111/echo.70398","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This research aims to assess the impact of coronary microvascular dysfunction (CMD) on the systolic function of the left ventricle (LV) in patients with ischemia and no obstructive coronary artery disease (INOCA) by employing three-dimensional speckle tracking echocardiography (3D-STE).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A group of 66 individuals with INOCA participated in the research. They all went through regadenoson stress echocardiography and measurement of coronary flow velocity reserve (CFVR). Patients were divided into a CMD group with CFVR values less than 2.0 and a control group with CFVR values of 2.0 or higher.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared with controls, the CMD group showed reductions in stress global longitudinal strain (GLS), stress global area strain (GAS), the change in GLS from rest to stress (ΔGLS), and the change in GAS from rest to stress (ΔGAS) (all <i>p</i> &lt; 0.001). All four strain parameters exhibited significant correlations with CFVR. Univariate analysis revealed that stress GLS, stress GAS, ΔGLS, and ΔGAS possessed good predictive value for CMD, among which ΔGAS had higher predictive value, having areas under the curve (AUC) of 0.923.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Strain parameters derived from 3D-STE under pharmacologic stress demonstrate excellent benefits in assessing LV systolic function in CMD patients. These parameters, especially ΔGAS, may serve as novel predictive indicators for the clinical assessment of CMD.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Valve: Ventricular Resilience as a Survival Predictor in TAVR for Pure Aortic Regurgitation","authors":"Matteo Pernigo,&nbsp;Salvatore Lavio,&nbsp;Andrea Buono","doi":"10.1111/echo.70395","DOIUrl":"10.1111/echo.70395","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Left Ventricular, Left Atrial, and Right Ventricular Function in Patients With Behçet's Disease by Strain Echocardiography","authors":"Mucahit Tan,&nbsp;Rumeysa Bilmez Tan,&nbsp;Yuksel Kaya,&nbsp;Muhammed Batur","doi":"10.1111/echo.70397","DOIUrl":"10.1111/echo.70397","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Behçet's disease (BD) can lead to a wide spectrum of cardiovascular manifestations. Strain echocardiography has emerged as a prominent modality in clinical practice owing to its significant prognostic value and ability to detect subclinical cardiac involvement in various cardiovascular diseases. This study was designed to evaluate left ventricular (LV), left atrium (LA), and right ventricular (RV) function in BD patients using strain echocardiography.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 61 participants were included in the study, comprising 27 patients with BD and 34 healthy controls. After medical histories and cardiac symptoms were obtained from all participants, basic echocardiographic parameters were recorded, and LV, LA, and RV functions were assessed using strain echocardiography.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No significant differences were observed between the two groups in terms of cardiac chamber dimensions and diastolic parameters. No significant difference was observed in global longitudinal strain values between the BD and control groups (<i>p</i> = 0.078). Similarly, no significant differences were found in right ventricular strain values. Regarding LA strain (LAS) parameters, LASr was found to be significantly lower in the BD group compared with the control group (<i>p</i> = 0.035). In the subgroup analysis comparing BD patients with and without uveitis, there were no statistically significant differences in LASr (<i>p</i> = 0.813), LAScd (<i>p</i> = 0.963), or LASct (<i>p</i> = 0.911).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In conclusion, our study did not show any deterioration in LV or RV function in BD, but it did show deterioration in LA mechanical function.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146013299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating the Unique Challenge of Pulmonary Hypertension From Left-to-Right PDA Shunts in Two Cases of Congenital Diaphragmatic Hernia","authors":"John T. Wren Jr,&nbsp;Rhucha Joshi,&nbsp;Patrick J. McNamara","doi":"10.1111/echo.70396","DOIUrl":"10.1111/echo.70396","url":null,"abstract":"<div>\u0000 \u0000 <p>Pulmonary hypertension (PH) in congenital diaphragmatic hernia (CDH) is nearly universal yet incredibly complex. A patent ductus arteriosus (PDA) is increasingly utilized to both monitor echocardiographically and manage CDH-PH. However, as pulmonary pressures are driven by both vascular resistance <i>and</i> blood flow, there is a risk that as the former improves, PH may in fact worsen from pathologic left-to-right (LtR) PDA shunting. Herein, we describe two cases of neonatal CDH whose PH was complicated by pathologic LtR PDA shunting and pulmonary overcirculation and improved following resolution of the transductal shunt, highlighting the underrecognized risk of pathologic PDA shunts in CDH.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2D Contour: A Simplified Approach for Left Atrial Reservoir Strain","authors":"Giacomo Ingallina,&nbsp;Riccardo Colombi,&nbsp;Paola Cunsolo,&nbsp;Gabriele Paci,&nbsp;Davide Margonato,&nbsp;Francesco Ancona,&nbsp;Giorgio Fiore,&nbsp;Carlo Gaspardone,&nbsp;Claudia Palomba,&nbsp;Noemi Russo,&nbsp;Stefano Stella,&nbsp;Leone Giovanni Musci,&nbsp;Federico Biondi,&nbsp;Ludovica Bognoni,&nbsp;Vincenzo Rizza,&nbsp;Monica Barki,&nbsp;Francesco Maisano,&nbsp;Eustachio Agricola","doi":"10.1111/echo.70359","DOIUrl":"10.1111/echo.70359","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Left atrial strain reservoir (LASr) has emerged as a useful parameter in assessing diastolic dysfunction and heart failure with preserved ejection fraction. LASr is typically assessed using speckle-tracking echocardiography (STE), which was developed to measure strain in the left ventricle. Despite its strength demonstrated in several clinical studies, the application of STE to the left atrium presents well-known limitations: thin walls, anatomical discontinuities, far-field location, and inter-vendor variability. The present study aims to evaluate the efficacy of an alternative method for assessing LASr, based on the percentage shortening of the atrial wall contour, by directly comparing it with STE-derived LASr values.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We retrospectively analyzed 246 patients in sinus rhythm with severe organic mitral regurgitation. The 2D contour strain method quantifies changes in the length of the two-dimensional (2D) endocardial atrial wall contour between end-systolic and end-diastolic frames. The peak strain value is calculated as: (maximum perimeter length−minimum perimeter length)/maximum perimeter length × 100.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>2D contour strain measurements were feasible in all patients. A strong correlation was observed between STE-derived and 2D contour-derived LASr values, with an <i>R</i>-value of 0.93. On average, 2D contour strain measurements underestimated LA peak strain by approximately 1% compared to STE. The consistency of 2D contour LA strain measurements, as assessed by inter- and intra-observer reproducibility, was excellent.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These findings suggest that 2D contour LA strain is a feasible and reliable alternative to STE for assessing LASr. This approach is particularly valuable in echocardiography labs where STE software for LA is unavailable.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right Aortic Arch With Bilateral Ductus Arteriosus, Aberrant Left Subclavian Artery, Interrupted Left Carotid Artery","authors":"Cosimo Marco Campanale,&nbsp;Serena Ventrella,&nbsp;Luciano Pasquini,&nbsp;Alessandra Toscano","doi":"10.1111/echo.70349","DOIUrl":"10.1111/echo.70349","url":null,"abstract":"<div>\u0000 \u0000 <p>We show an exceptional case of a right aortic arch (RAA) in a patient with DiGeorge syndrome, breaking the rule that the first epiaortic vessel courses to the contralateral side of the aortic arch. This is a RAA with an aberrant left subclavian artery (ALSA) and an isolated left carotid artery (ILCA) arising from the left pulmonary artery (LPA) via a left anterior ductus arteriosus (LADA), along with bilateral ductus arteriosus. This unique case highlights educational pitfalls in using a simple rule to define arch sidedness. Although challenging, echocardiographic diagnosis of such vascular anomalies is feasible in expert hands. The color-flow and Doppler pattern of the epiaortic vessels provide important information about their arrangement and connection to the aortic arch. Bilateral ductus arteriosus is often a marker of complex vascular anomalies, which are frequently associated with genetic syndromes.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive Models of a Future Coronary Artery Calcium Score in a Black Cohort: The GENOA Study","authors":"Edmund K. Kerut,&nbsp;Ronald Horswell,&nbsp;Adebamike Oshunbade,&nbsp;Michael E. Hall,&nbsp;Filip To,&nbsp;Ervin Fox,&nbsp;Michael R. McMullan,&nbsp;Kenneth R. Butler","doi":"10.1111/echo.70388","DOIUrl":"10.1111/echo.70388","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This retrospective study of a Black cohort sought to create predictive models to calculate the probability of a coronary artery calcium score (CACS) about one decade after obtaining cardiovascular risk measures.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design and Setting</h3>\u0000 \u0000 <p>Participants (<i>n</i> = 656) in GENOA had CV risk variables measured (1995–2000) and a CACS about one decade later (2009–2011). Using multivariate regression, computer models were written to calculate the probability of a future CACS of zero, ≥ 10, and ≥ 100. ROC values were 0.78, 0.77, and 0.76, respectively. Machine learning models did not perform any better than multivariate regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Age, height, smoking duration, sex, and hypertension were significant for all three models in predicting a future CACS. Height was inversely related to future CACS, but weight and BMI were not contributory to the models. Lipid-lowering medications and exercise were associated with an increased CACS, the so-called CACS “paradox.”</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Predictive models of a future CACS such as these may help in identifying important risk factors for a future CACS. By identifying these risk factors and implementing early modification of CV risk factors, the development of CV disease may be slowed.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"43 1","pages":""},"PeriodicalIF":1.4,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145967618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}