{"title":"The Study of Precise Evaluation and Comparison of LVEF on Technetium Scan With Echocardiography in Patients With LBBB (SPECT-LBBB Study).","authors":"Vijaya Kumar Varada, Bhanu Duggal, Shishir Soni","doi":"10.1111/echo.70308","DOIUrl":"https://doi.org/10.1111/echo.70308","url":null,"abstract":"<p><strong>Background: </strong>Left bundle branch block (LBBB) is an indication for cardiac resynchronization therapy (CRT) in patients with severe left ventricular (LV) systolic dysfunction. Accurate estimation of LV ejection fraction (LVEF) by echocardiography is often challenging in LBBB, leading to uncertainty regarding CRT eligibility. Alternative imaging modalities, such as contrast echocardiography (CE) and single-photon emission computed tomography (SPECT) may provide more reliable LVEF in these cases.</p><p><strong>Aim: </strong>This study aimed to compare LVEF estimation by unenhanced trans-thoracic echocardiography (UE-TTE), CE, and SPECT in patients with LBBB and significant discrepancy (≥5%) between prior UE-TTE reports.</p><p><strong>Methods: </strong>Sixty patients with LBBB referred for SPECT between May 2022 and May 2023 underwent LVEF assessment with UE-TTE, CE, and SPECT. Correlation and absolute differences in LVEF estimate across modalities were analyzed.</p><p><strong>Results: </strong>LVEF on CE correlated strongly with SPECT (r = 0.976, r<sup>2</sup> = 0.952) outperforming UE-TTE (r = 0.824, r<sup>2</sup> = 0.679). Among patients with LVEF ≤ 35% by UE-TTE, 13 of 34 had LVEF ≥ 40% on SPECT, compared to only one of 21 by CE. An absolute LVEF difference ≥10% was observed in 40% (SPECT vs. UE-TTE) and 0.5% (SPECT vs. CE).</p><p><strong>Conclusion: </strong>In patients with LBBB and discordant LVEF values on UE-TTE, secondary evaluation with CE or SPECT improves accuracy of LVEF assessment, potentially optimizing CRT eligibility and clinical decision making.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 10","pages":"e70308"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camila Mota Guida, Jonathan Batista Souza, Fernando Yue Cesena
{"title":"The Association Between Diabetes Mellitus and Left Atrial Strain in Individuals With Hypertension: Authors' Reply to the Letter to the Editor.","authors":"Camila Mota Guida, Jonathan Batista Souza, Fernando Yue Cesena","doi":"10.1111/echo.70312","DOIUrl":"https://doi.org/10.1111/echo.70312","url":null,"abstract":"<p><p>Diabetes mellitus has been increasingly recognized as a contributor to subclinical atrial dysfunction, particularly in hypertensive patients with preserved left ventricular ejection fraction. In our study, we demonstrated an association between diabetes and impaired left atrial mechanics assessed by two-dimensional speckle-tracking echocardiography. Although the cross-sectional design does not allow causal inference, our findings support the hypothesis that diabetes may adversely affect atrial strain independent of overt cardiovascular disease. We adjusted for relevant clinical and echocardiographic variables, though residual confounding cannot be excluded. Patients with known atrial fibrillation were excluded, and although prolonged rhythm monitoring was not performed, this limitation reflects the real-world challenges of detecting silent paroxysmal arrhythmias. Echocardiography was chosen for its accessibility and widespread applicability, and reproducibility analyses confirmed good intra- and inter-observer agreement. Validation against other modalities such as cardiac magnetic resonance imaging was beyond the scope of the present study.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 10","pages":"e70312"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sridhar Mangalesh, Laura Marcela Romero-Acero, Michele Nanna
{"title":"Integrating Strain, Myocardial Work, and Coronary Flow Into Stress Echocardiography: A Precision Framework for Ischemia Diagnosis.","authors":"Sridhar Mangalesh, Laura Marcela Romero-Acero, Michele Nanna","doi":"10.1111/echo.70311","DOIUrl":"https://doi.org/10.1111/echo.70311","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 10","pages":"e70311"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Echocardiographic Features of Cardiomyopathies: A Comprehensive Review.","authors":"Ghassan Hamdan Al-Naami","doi":"10.1111/echo.70309","DOIUrl":"https://doi.org/10.1111/echo.70309","url":null,"abstract":"<p><p>Cardiomyopathies represent a heterogeneous group of myocardial diseases characterized by structural and functional abnormalities that can lead to heart failure, arrhythmias, and sudden cardiac death. Echocardiography remains the first-line, non-invasive imaging modality for the evaluation of cardiomyopathies, owing to its broad availability, safety profile, and diagnostic versatility. This review comprehensively outlines the echocardiographic features associated with the major morphofunctional subtypes of cardiomyopathy: dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), restrictive cardiomyopathy (RCM), arrhythmogenic right ventricular cardiomyopathy (ARVC), and left ventricular non-compaction cardiomyopathy (LVNC). Emphasis is placed on both adult and pediatric populations, with attention to age-specific diagnostic criteria and measurement standards. The article also includes structured tabular summaries to facilitate clinical interpretation and application across diverse patient settings. Through an integrated and standardized echocardiographic approach, this review aims to support accurate diagnosis, effective monitoring, and informed therapeutic decision-making in the management of cardiomyopathies.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 10","pages":"e70309"},"PeriodicalIF":1.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Adult With Giant Vertical Vein in Total Anomalous Pulmonary Venous Connection Combined With Pulmonary Valve Stenosis","authors":"Bingjie Li, Xi Li, Fang Wang, Xin Wei","doi":"10.1111/echo.70294","DOIUrl":"https://doi.org/10.1111/echo.70294","url":null,"abstract":"<p>A 27-year-old male who had been incidentally discovered with cardiomegaly during a routine physical examination, presented with a history of occasional dyspnea on exertion for 20 years. The patient was diagnosed with giant vertical vein in total anomalous pulmonary venous connection combined with pulmonary valve stenosis.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 10","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145197322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa Steen Duus, Maria Dons, Morten Lock Hansen, Rene Worck, Martin H. Ruwald, Arne Johannessen, Jim Hansen, Tor Biering-Sørensen
{"title":"Echocardiographic Markers of Prognosis in Patients Undergoing Ventricular Arrhythmia Ablation","authors":"Lisa Steen Duus, Maria Dons, Morten Lock Hansen, Rene Worck, Martin H. Ruwald, Arne Johannessen, Jim Hansen, Tor Biering-Sørensen","doi":"10.1111/echo.70307","DOIUrl":"10.1111/echo.70307","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Radiofrequency catheter ablation (RFA) plays an increasing role in the treatment of ventricular arrhythmias (VAs). This study aimed to evaluate the echocardiographic and clinical characteristics of patients undergoing first-time RFA for VAs and to identify risk factors associated with VA recurrence, implantable cardioverter-defibrillator (ICD) therapy, and mortality.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We studied patients scheduled for first-time RFA for VAs from 2011 to 2022 with available transthoracic echocardiography before the procedure. The primary outcome was defined as VA recurrence, and the secondary outcome was defined as appropriate ICD therapy and mortality. Uni- and multivariable Cox hazards regression models were used to assess the prognostic value of cardiac structure and function by echocardiography.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 218 patients (mean age 61 years [±15], 62% men, mean LVEF 51% [IQR: 44; 57]) underwent RFA during the study period. Of these, 90 patients (41%) had VA recurrence while 52 patients (24%) developed the secondary outcome during a median follow-up time of 3.1 years (IQR: 1.1; 6.7 years). Patients with ventricular tachycardia had significantly more right—and left ventricular (LV) dysfunction, compared to patients with premature ventricular contractions. No echocardiographic measures were associated with VA recurrence, while several echocardiographic measures were associated with the secondary outcome. LV mass index, LV ejection fraction, global longitudinal strain, and VA recurrence showed the highest predictive values of the secondary outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In patients undergoing RFA for VAs, several echocardiographic measures may identify patients at risk of an adverse outcome.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 10","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70307","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimizing Ultrasound-Guided Placement of Cardiac Implantable Electronic Devices: Current Uses and Challenges","authors":"Maham Bilal, Areesha Tariq, Yumna Jamil, Shehzaib Ali Azfar, Habib Rehman Khan","doi":"10.1111/echo.70302","DOIUrl":"10.1111/echo.70302","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>Cardiac implantable electronic devices are an effective treatment for heart rhythm disorders. Currently, x-ray imaging—especially fluoroscopy—is the standard method used to guide the implantation process and assess its effectiveness. However, due to risks associated with radiation exposure, ultrasound is being explored as an alternative to traditional imaging modality. The growing interest in adopting ultrasound as the primary imaging modality during implantation emphasizes the need for practitioners, particularly cardiac electrophysiologists, to be aware of its advantages as well as its limitations. This article discusses the existing and possible future uses of ultrasound in CIED implantation, explores new US-based technologies that could support its usage, and discusses the potential drawbacks associated with it. Additionally, it offers recommendations for enhancing the proficiency of ultrasound-guided implantation and mitigating its limitations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Summary</h3>\u0000 \u0000 <div>\u0000 <ul>\u0000 \u0000 <li><b>Question</b>: What is the scope of use of ultrasound in cardiac device implantation?</li>\u0000 \u0000 <li><b>Findings</b>: Studies show that ultrasound is safe for vascular access to reduce complications; aid in lead implantation on the ventricular septum, preventing cardiac perforation; and adjust slack to prevent lead-related tricuspid regurgitation.</li>\u0000 \u0000 <li><b>Clinical Relevance Statement</b>: The clinical relevance of these findings is to help physicians utilize ultrasound during routine cardiac device implantation to enhance clinical outcomes and minimize complications, especially in the era of left bundle branch area pacing.</li>\u0000 </ul>\u0000 </div>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 10","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70302","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amr Mansour Mohamed, Mahmoud Abdelsabour, Mohamed Aboel-Kassem F. Abdelmegid, Areej AlKhateeb, Ahmed M. Moheb, Hosam Hasan-Ali
{"title":"Cardiac Reverse Remodeling in Adults and Pediatrics After Transcatheter Patent Ductus Arteriosus Closure: A Multicenter Echocardiographic Study","authors":"Amr Mansour Mohamed, Mahmoud Abdelsabour, Mohamed Aboel-Kassem F. Abdelmegid, Areej AlKhateeb, Ahmed M. Moheb, Hosam Hasan-Ali","doi":"10.1111/echo.70305","DOIUrl":"10.1111/echo.70305","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Whether there is a difference in cardiac reverse remodeling after transcatheter Patent ductus arteriosus (PDA) closure between adults and pediatrics, caused by the longstanding shunt in adults, is not well studied.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We studied 22 adults and 35 pediatric patients who were referred for percutaneous closure of PDA, using volumetric echocardiography and speckle tracking echocardiography (STE) before closure, immediately after, then 3 months, and 6 months after PDA closure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Left ventricular (LV) ejection fraction (EF), global longitudinal (GLS), and circumferential strains (GCS) dropped significantly immediately after the procedure, associated with a drop in LV and left atrial (LA) diameters and volumes in both groups. In adult patients, LA reservoir and conduit strains (LASr and LAScd) also dropped. Six months later, and compared to their baseline values, adult patients had significantly lower LV GCS (−19.02 ± 3.47 % vs. −20.27 ± 3.76 %), while LVEF (57.59 ± 6.96 % vs. 59.83 ± 5.70 %) and LV GLS (−19.15 ± 3.38 % vs. −19.82 ± 2.06 %) were insignificantly lower. In contrast, the pediatric patients showed that LVEF (63.56 ± 6.44% vs. 63.89 ± 5.82%), LV GLS (−23.60 ± 2.38% vs. −23.17 ± 2.88%), and LV GCS (−22.95 ± 3.01 vs. −22.86 ± 2.51%) improved to their baseline values, or even slightly higher. LA contraction strain (LASct) improved significantly in both groups after PDA closure.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>While both groups experienced an initial drop in cardiac function post-PDA closure, pediatric patients showed quicker recovery, likely due to the longer hemodynamic effect of the PDA in adults. PDA closure positively impacted LA contraction strain in both age groups.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 10","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel M. Spevack, Pragya Ranjan, Yeraz Khachatoorian, Michael Broker, Chan Woo Kim, Kerry Nevin, Mala Sharma, Divya Malhotra, Srihari Naidu
{"title":"Inclusion of the Right Ventricular Muscle Bundle During Interventricular Septal Measurement Improves Diagnostic Accuracy for Hypertrophic Cardiomyopathy","authors":"Daniel M. Spevack, Pragya Ranjan, Yeraz Khachatoorian, Michael Broker, Chan Woo Kim, Kerry Nevin, Mala Sharma, Divya Malhotra, Srihari Naidu","doi":"10.1111/echo.70299","DOIUrl":"https://doi.org/10.1111/echo.70299","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Measurement of the interventricular septum (IVS) is a key diagnostic and prognostic parameter in the evaluation of hypertrophic cardiomyopathy (HCM). Right ventricular muscle bundles (RVMB) that parallel the IVS complicate septal measurement on both echocardiography and magnetic resonance imaging. Current guideline statements reference left ventricular wall thickness measurements greater than or equal to 15 mm as part of the diagnostic criteria for HCM. The medical literature lacks published data on the impact of including RVMB as part of the IVS measurement and its influence on diagnostic accuracy for HCM.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We measured the IVS and RVMB separately on echocardiography in 97 consecutive subjects referred for both echocardiography and magnetic resonance imaging (MRI) as part of the initial evaluation for HCM. Subjects were categorized as having or not having HCM based on current practice guidelines. Patients with HCM were sub-categorized as having septal involvement (HCM-Sep) or primarily apical hypertrophy (HCM-Ap). This was done because subjects with obvious HCM-Ap could be diagnosed with HCM irrespective of IVS thickness.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared to subjects who did not have HCM, those with HCM-Sep had both increased IVS (15.4 ± 2.7 vs. 9.8 ± 1.9 mm, <i>p</i> < 0.001) and RVMB thickness (5.2 ± 3.1 vs. 1.9 ± 1.9 mm, <i>p</i> < 0.001). In the whole study group, the area under the receiver operating characteristic (ROC) curve for HCM was higher (0.83 [95% confidence interval (CI): 0.75, 0.91]) when the RVMB was included in the IVS measurement compared to when it was excluded (0.75 [95% CI: 0.68, 0.81]). When the subjects with HCM-Ap were excluded, the area under the ROC curve for HCM was higher (0.94 [95% CI: 0.89, 0.99]) when the RVMB was included in the IVS measurement compared to when it was excluded (0.82 [95% CI: 0.75, 0.89]). The number of subjects classified correctly for HCM improved from 78% to 94% when the RVMB was included.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Inclusion of the RVMB in the measurement of IVS thickness on echocardiography may improve overall diagnostic accuracy for HCM. In addition, RVMB thickness is increased and is more often visible on parasternal long-axis imaging in subjects with HCM, consistent with being part of the HCM pathology. This is particularly true in those with HCM-Sep. These data have implications for the standardization of echocardiographic and MRI reporting in HCM.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 9","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Cardiac Malformation: Isolated Double-Orifice Mitral Valve","authors":"Leizhi Ku, Zheng Liu, Yuhang Wang, Xiaojing Ma","doi":"10.1111/echo.70304","DOIUrl":"10.1111/echo.70304","url":null,"abstract":"<div>\u0000 \u0000 <p>The double-orifice mitral valve (DOMV) is a rare congenital valve malformation characterized by a mitral valve with a single fibrous annulus, resulting in two orifices. Due to a lack of understanding and awareness of its echocardiographic or coronary computed tomographic angiography (CCTA) characteristics, there is a risk of misdiagnosis. We report a case of a 64-year-old woman who was found to have an isolated double orifice mitral valve malformation on transthoracic echocardiography and CCTA. Echocardiography is the first-line tool for diagnosing DOMV. CCTA is critical in the complementary diagnosis of DOMV combined with other coronary artery anomalies and extracardiac structure abnormalities.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 9","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145082218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}