Giacomo Ingallina, Giorgio Fiore, Francesco Ancona
{"title":"Preoperative Assessment of Degenerative Mitral Regurgitation: Advancing Toward a Less Invasive Approach With Three-Dimensional Transthoracic Echocardiography?","authors":"Giacomo Ingallina, Giorgio Fiore, Francesco Ancona","doi":"10.1111/echo.70066","DOIUrl":"https://doi.org/10.1111/echo.70066","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":"e70066"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association of Epicardial Adipose Tissue With Left Atrial Function in Heart Failure With Preserved Ejection Fraction.","authors":"Hidekazu Tanaka","doi":"10.1111/echo.70072","DOIUrl":"https://doi.org/10.1111/echo.70072","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":"e70072"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elad M Bar Gil, Ruslan Sergienko, Nir Roguin, Shoham Birman, Sergio L Kobal
{"title":"Prognostic Value of Transvalvular Flow Rate in Aortic Stenosis: Implications for Risk Stratification.","authors":"Elad M Bar Gil, Ruslan Sergienko, Nir Roguin, Shoham Birman, Sergio L Kobal","doi":"10.1111/echo.70077","DOIUrl":"https://doi.org/10.1111/echo.70077","url":null,"abstract":"<p><strong>Background: </strong>Timing of treatment of aortic stenosis (AS) is of key importance. AS severity is currently determined by transthoracic echocardiography (TTE) with a main focus on mean trans-aortic gradients. However, echocardiography has its limitations. The transvalvular flow rate (Q), is defined as the ratio of stroke volume (SV) to ejection time (ET): Q = SV/ET.</p><p><strong>Purpose: </strong>To examine the prognostic value of aortic transvalvular flow rate (Q), in patients with moderate or severe AS.</p><p><strong>Methods: </strong>Clinical data from 824 patients diagnosed with AS between 2017 and 2020, and followed up until 2022 for four clinical outcomes: mortality, congestive heart failure (CHF), transcatheter aortic valve implantation (TAVI), and surgical aortic valve replacement (SAVR) was used for this retrospective study. Univariate and multivariate regression analyses were performed for the whole cohort and for the moderate AS subgroup, to identify prognostic markers. Kaplan-Meier survival analysis was conducted for different transvalvular flow rates and AS severities.</p><p><strong>Results: </strong>Findings demonstrate that lower Q is a significant risk factor for all-cause mortality even when adjusted for other echocardiographic and clinical variables. Survival analysis for the composite outcome occurrence (TAVI, SAVR, CHF, or mortality) and mortality showed significant differences between groups stratified by AS severity and Q (p value <0.0001). Specifically, Q was more substantial in the moderate AS group.</p><p><strong>Conclusion: </strong>Transvalvular flow rate (Q) is independently prognostic for all-cause mortality. Furthermore, patients with moderate AS and lower Q should be closely monitored. Flow rate assessment should be integrated into the diagnosis, classification, and prognosis framework for AS.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":"e70077"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Left Atrial Mechanics and Atrioventricular Coupling in Hypertension With Supra-Normal Left Ventricular Ejection Fraction.","authors":"Chong Liu, Wen-Jun Xu, Jia-Wei Tian","doi":"10.1111/echo.70079","DOIUrl":"https://doi.org/10.1111/echo.70079","url":null,"abstract":"<p><strong>Objectives: </strong>Supra-normal left ventricular ejection fraction (snLVEF) represents a heterogeneous group with distinct prognoses. Left atrial (LA) strain, measured by speckle tracking echocardiography (STE), is a validated prognostic indicator. This study aimed to evaluate LA and left ventricular (LV) mechanical strains in hypertensive patients with snLVEF.</p><p><strong>Methods: </strong>This retrospective study included 101 patients (mean age 59.7 ± 8.4 years; 61.4% men) with primary arterial hypertension and preserved LVEF (≥50%). Patients were categorized into low-normal LVEF (lnLVEF; 50%-59%), mid-normal LVEF (mnLVEF; 60%-69%), and snLVEF (≥70%). LV global longitudinal strain (LVGLS) and LA strains during reservoir (LASr), conduit (LAScd), and contraction (LASct) phases were measured using STE.</p><p><strong>Results: </strong>Relative wall thickness was significantly higher in snLVEF patients compared to mnLVEF (p < 0.01), with no difference in LVGLS (p = 0.933). Compared to mnLVEF, snLVEF patients had reduced LASr and LAScd (both p < 0.01) but preserved LASct (p = 0.057). In contrast, lnLVEF patients showed greater reductions in all phasic LA strains (all p < 0.01). Loess regression revealed an inverted U-shaped relationship between LASr and LVEF, peaking at LVEF 65%-70%. The mitral E/e'<sub>mean</sub> ratio and LVGLS correlated moderately to strongly with LASr (r = -0.39 and r = -0.65, respectively; both p < 0.001).</p><p><strong>Conclusion: </strong>Hypertensive patients with snLVEF exhibit impaired LA reservoir and conduit functions while maintaining pump function, suggesting snLVEF may be an intermediate stage between mnLVEF and lnLVEF as hypertension progresses. Further studies are needed to explore the prognostic potential of LA strain in this population.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":"e70079"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tugba Kemaloglu Oz, Vladyslav Kavalerchyk, Krasimira Hristova, Alex Dos Santos Felix, Anosh Shane Sivashanmugarajah, Angus A Baumann, Alexander Mladenow
{"title":"From Traditional to Cutting-Edge: Transforming Pulmonary Valve Assessment With Advanced Echocardiography Techniques.","authors":"Tugba Kemaloglu Oz, Vladyslav Kavalerchyk, Krasimira Hristova, Alex Dos Santos Felix, Anosh Shane Sivashanmugarajah, Angus A Baumann, Alexander Mladenow","doi":"10.1111/echo.70058","DOIUrl":"https://doi.org/10.1111/echo.70058","url":null,"abstract":"<p><p>The pulmonary valve (PV), although often less emphasized than other heart valves, is crucial for cardiac function and hemodynamics. Historically, the PV has been underrepresented in echocardiographic assessments due to its rare involvement in pathological conditions, particularly in adults. Additionally, the anatomical position of the PV makes it one of the most challenging valves to visualize using conventional echocardiography. Traditional two-dimensional (2D) techniques, while foundational, have limitations in capturing the full spectrum of valve pathology and dynamics. Recent advancements in echocardiography, especially the integration of three-dimensional (3D) imaging, have significantly enhanced the assessment of PV disorders. 3D echocardiography (3DE) offers superior accuracy in visualizing valve morphology and function, overcoming the limitations of angle dependency and suboptimal imaging planes typical of 2D assessments. This evolution in imaging techniques facilitates more precise diagnoses and improved management of conditions such as pulmonary stenosis (PS) and regurgitation (PR). This review explores the transition from conventional echocardiographic methods to advanced approaches that are reshaping our understanding of the PV, emphasizing the importance of incorporating these cutting-edge techniques into routine clinical practice to enhance patient outcomes.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":"e70058"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Relevance of Senior-Supervised Transthoracic Echocardiography in Clinical Practice and Research: An Editorial Commentary and Systematic Review.","authors":"Daniel A Morris","doi":"10.1111/echo.70085","DOIUrl":"10.1111/echo.70085","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":"e70085"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hong Ma, HongPing Wu, XiaoXuan Sun, Qiang Wang, YaGuo Zheng
{"title":"The Evaluation of Right Ventricular Synchrony by Two-Dimensional Speckle Tracking Echocardiography in Connective Tissue Disease-Associated Pulmonary Arterial Hypertension.","authors":"Hong Ma, HongPing Wu, XiaoXuan Sun, Qiang Wang, YaGuo Zheng","doi":"10.1111/echo.70060","DOIUrl":"https://doi.org/10.1111/echo.70060","url":null,"abstract":"<p><strong>Objectives: </strong>Numerous studies have demonstrated impaired right ventricular (RV) synchronicity in pulmonary arterial hypertension (PAH). However, few studies have focused on connective tissue disease (CTD)-associated PAH. This study evaluates RV dyssynchrony and its prognostic value in CTD-associated PAH.</p><p><strong>Methods: </strong>One hundred thirteen CTD patients and 32 healthy controls were consecutively recruited. The patients were further divided into two groups: the CTD-nonPAH group (sPAP ˂ 36 mmHg, n = 60) and the CTD-PAH group (sPAP ≥ 36 mm Hg, n = 53). RV dyssynchrony was evaluated by determining the standard deviation of the heart rate-corrected intervals from QRS onset to peak strain for the four segments (RV-SD4) using 2D speckle-tracking echocardiography (2D-STE). All patients were followed up, and the primary endpoint was clinical worsening.</p><p><strong>Results: </strong>Compared to the health control, the CTD patients exhibited obviously prolonged RV-SD4 (13.3 ± 6.8 ms vs. 41.2 ± 36.5 ms, p < 0.001). Among 113 CTD patients, the CTD-PAH patients had longer RV-SD4 than the CTD-nonPAH patients (20.8 ± 9.9 ms vs. 64.3 ± 41.6 ms, p < 0.001). RV-SD4 was moderately positively correlated with RV longitudinal strain (r = 0.632, p < 0.001), sPAP (r = 0.644, p < 0.001), and were negatively correlated with TAPSE (r = -0.547, p < 0.001), and FAC (r = -0.611, p < 0.001). In the follow-up, 23 patients experienced clinical worsening. The ROC analysis suggested that RV-SD4 level >60.6 ms predicted clinical worsening with 91.3% sensitivity and 66.7% specificity (AUC = 0.891, p < 0.001). Multivariate Cox analysis showed that TAPSE (HR = 0.739; 95% CI 0.623-0.878; p = 0.001) and RV-SD4 (HR = 6.148; 95% CI 1.718-22.000; p = 0.005) were independent predictive parameters of clinical worsening.</p><p><strong>Conclusion: </strong>CTD patients exhibit impaired RV synchronicity, which is linked to RV function and pulmonary artery pressure. RV dyssynchrony could predict clinical worsening in CTD-PAH.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":"e70060"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Davide Marchetti, Michele Gallazzi, Giulia Nemola, Marco Stracqualursi, Blanca Prestini, Alessandro Masini, Maria Clara Alessandrello, Sara Belleggia, Pasquale Paolisso, Daniele Andreini, Edoardo Conte
{"title":"Utility of Cardiovascular CT in Ischemic Heart Disease.","authors":"Davide Marchetti, Michele Gallazzi, Giulia Nemola, Marco Stracqualursi, Blanca Prestini, Alessandro Masini, Maria Clara Alessandrello, Sara Belleggia, Pasquale Paolisso, Daniele Andreini, Edoardo Conte","doi":"10.1111/echo.70032","DOIUrl":"10.1111/echo.70032","url":null,"abstract":"<p><p>Cardiac computed tomography angiography (CCTA) has acquired a pivotal role in modern cardiology. It represents the gold standard for noninvasive coronary imaging. Moreover, CCTA permits a comprehensive evaluation of atheromatic burden and plaque composition. This study aims to review the impact of CCTA across the different presentations of ischemic heart disease, from primary prevention to the evaluation of patients requiring revascularization.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":"e70032"},"PeriodicalIF":1.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}