Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques最新文献

{"title":"Impaired Left Atrial Reservoir Strain Causes Exercise-Induced Pulmonary Hypertension in Patients With Preserved Left Ventricular Ejection Fraction","authors":"Masaki Kinoshita,&nbsp;Tatsuro Tasaka,&nbsp;Kaori Fujimoto,&nbsp;Makoto Saito,&nbsp;Sumiko Sato,&nbsp;Kazuhisa Nishimura,&nbsp;Katsuji Inoue,&nbsp;Shuntaro Ikeda,&nbsp;Takumi Sumimoto,&nbsp;Osamu Yamaguchi","doi":"10.1111/echo.70139","DOIUrl":"10.1111/echo.70139","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Exercise-induced pulmonary hypertension (EIPH), assessed using exercise stress echocardiography (ESE), is important in diagnosing early stage of heart failure (HF) with preserved ejection fraction (EF) and affects exercise tolerance and prognosis. Left atrial (LA) reservoir strain, which reflects the left ventricular filling pressure, is an associated factor with HF. This study aimed to investigate the association between the LA reservoir strain at rest and EIPH.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective analysis included 188 participants with a left ventricular EF ≥ 50% who underwent ESE. EIPH was defined as a peak tricuspid regurgitation (TR) pressure gradient &gt;50 mm Hg. HF events (HF hospitalization or diuretic use with brain natriuretic peptide ≥100 pg/mL) were evaluated in patients with ≥3 months follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirty-four (18.1%) patients were diagnosed with EIPH. LA reservoir strain at rest with an optimal cutoff value of 21% identified patients, with 73% sensitivity and 59% specificity. The multivariate logistic regression analysis indicated that LA reservoir strain was independently associated with EIPH. Furthermore, adding LA reservoir strain to the TR-velocity significantly improved EIPH discrimination. During a median follow-up period of 336 days, 29 patients (21.6%) experienced HF events. The hazard ratio for HF events in patients with LA reservoir strain ≤21% was 4.04 after adjusting for age and HFA-PEFF score (95% confidence interval, 1.29–12.7).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>LA reservoir strain at rest was associated with EIPH and HF events in patients with preserved EF, suggesting that impaired LA reservoir strain could increase the risk of HF.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To Each Imaging Modality, Their Own MAD","authors":"Kamil Stankowski,&nbsp;Georgios Georgiopoulos,&nbsp;Maria Lo Monaco,&nbsp;Federica Catapano,&nbsp;Renato Maria Bragato,&nbsp;Gianluigi Condorelli,&nbsp;Leandro Slipczuk,&nbsp;Marco Francone,&nbsp;Pier-Giorgio Masci,&nbsp;Stefano Figliozzi","doi":"10.1111/echo.70132","DOIUrl":"https://doi.org/10.1111/echo.70132","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The clinical significance of mitral annular disjunction (MAD) is uncertain. Imaging modality might impact the prevalence of MAD. We aimed to assess MAD prevalence at transthoracic echocardiography (TTE) and cardiac magnetic resonance (CMR) as well as their inter-modality agreement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This observational retrospective study included patients undergoing TTE and CMR within 6 months. MAD was defined as ≥1 mm systolic separation between the left atrial wall-mitral leaflet and the left ventricular (LV) wall. The maximum MAD longitudinal extent was measured. The inter-modality agreement for MAD diagnosis was evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>One hundred twenty four patients (59 ± 17 years; 62% male) were included. MAD was detected in 60 (48%) using CMR and in 10 (8%) using TTE. All patients with MAD on TTE had MAD on CMR. The inter-modality agreement was low (Cohen's kappa = 0.17) but improved when the diagnostic cut-off was increased from 1 to 5 mm (Cohen's kappa = 0.66). The median longitudinal length of MAD was 2.0 mm (25th–75th percentiles: 1.5–3.0) by CMR and 4.0 mm (25th–75th percentiles: 2.7–4.5) by TTE with moderate agreement (intraclass correlation coefficient = 0.66).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>MAD of limited extent is common on CMR and more than two thirds of patients showing MAD on CMR did not have MAD on TTE. The inter-modality agreement between TTE and CMR increased when the diagnostic threshold for MAD was increased from 1 to 5 mm. Methodological discrepancies impact MAD assessment and contribute to the discordant prevalence and clinical significance reported in the literature.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70132","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Defining Normal Reference Ranges of Left Ventricular Global Longitudinal Strain Among Different Vendors: Are We There Yet?","authors":"Michele Nanna,&nbsp;Laura Marcela Romero Acero,&nbsp;Pei-Lun Lee","doi":"10.1111/echo.70129","DOIUrl":"https://doi.org/10.1111/echo.70129","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143629839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right Atrial Function and Right Ventricular Diastolic Function and Their Relation With Exercise Capacity in OSAS","authors":"Bang Du,&nbsp;Shuxin Liang,&nbsp;Rui Zhang,&nbsp;Wenjia Shi,&nbsp;Ruonan Wang,&nbsp;Yahong Qin,&nbsp;Aiai Chu","doi":"10.1111/echo.70091","DOIUrl":"https://doi.org/10.1111/echo.70091","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Right ventricular (RV) diastolic function and right atrial (RA) function are poorly characterized in patients with obstructive sleep apnea syndrome (OSAS), but may influence exercise capacity. We aimed to evaluate RA function and RV diastolic function in OSAS and study their relationship with exercise capacity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Fifty-three patients with OSAS and thirty age- and gender-matched controls prospectively underwent echocardiography and cardiopulmonary exercise testing to investigate RV diastolic function, RA function, and exercise capacity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Altered RV diastolic function in patients with severe OSAS was indicated by the increased tricuspid valve E/e′ ratio (TV E/e′), isovolumic relaxation time (IVRT), and by the reduced RV TDI e′ velocity. The TV E/e′ correlated modestly with peak VO₂ (<i>r</i> = −0.334, <i>p</i> &lt; 0.01). Patients with severe OSAS exhibited impaired RA total emptying fraction, RA passive emptying fraction, and RA reservoir strain (RARS), with RARS being associated with peak oxygen uptake (VO₂) (<i>r</i> = 0.451, <i>p</i> &lt; 0.01 for reservoir function).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Altered RA function and RV diastolic function in patients with OSAS are associated with impaired exercise capacity. The correlation of RA function and RV diastolic function with exercise capacity suggests that it may be important to evaluate RA function and RV diastolic function in this population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143629840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in Left Ventricular Function Assessed by 3D Echocardiography During Severe Central Hypovolemia in Healthy Humans","authors":"Kazukuni Hirabuki,&nbsp;Noritaka Hata,&nbsp;Marina Fukuie,&nbsp;Rina Suzuki,&nbsp;Tomoya Suda,&nbsp;Takahiro Uechi,&nbsp;Ai Hirasawa,&nbsp;Jun Sugawara,&nbsp;Takeaki Matsuda,&nbsp;Shigeki Shibata","doi":"10.1111/echo.70128","DOIUrl":"https://doi.org/10.1111/echo.70128","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Central hypovolemia is considered to lead to a compensatory increase in cardiac contractility. From a physiological perspective, left ventricular (LV) twisting motion, which plays an important role in maintaining cardiac output, should be enhanced during central hypovolemia, but previous studies have shown inconsistent findings. Using 3D echocardiography, we tested the hypothesis that the LV twisting and untwisting motion would be enhanced during severe central hypovolemia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Thirteen healthy men (25 ± 5 years old) underwent the maximal lower body negative pressure (LBNP) protocol; graded increase in LBNP loads up to presyncope. We evaluated the basic hemodynamics and LV function with 3D and Doppler echocardiography at each stage of LBNP. Indices were compared among baseline, half maximal LBNP (LBNP1/2max), and one stage before the presyncope (LBNPpre-max) to consider individual differences in orthostatic tolerance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In response to LBNP, ejection fraction (baseline: 62 ± 3, LBNP1/2max: 55 ± 5, LBNPpre-max: 43% ± 9%, mean ± SD, <i>p</i> &lt; 0.01, ANOVA), global longitudinal strain (−20.5 ± 2.8, −17.6 ± 2.7, −13.6% ± 4.7%, <i>p</i> &lt; 0.01), and global circumferential strain (−31.2 ± 3.7, −26.8 ± 3.3, −19.4% ± 5.3%, <i>p</i> &lt; 0.01) were weakened. Twist (15.2 ± 5.1, 14.5 ± 5.4, 20.9° ± 7.7°, <i>p</i> = 0.012) and peak untwisting rate (−138 ± 42, −164 ± 50, −245°/cm ± 88°/cm, <i>p</i> &lt; 0.01) were strengthened at the LBNPpre-max. e’ (14.1 ± 2.0, 11.1 ± 1.5, 8.2° ± 2.2 cm/s, <i>p</i> &lt; 0.01) decreased in response to LBNP, while E/e’ (5.8 ± 0.8, 5.4 ± 1.0, 7.8 ± 2.3, <i>p</i> &lt; 0.01) increased at LBNPpre-max.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The present findings indicate that LV twisting motion is enhanced during severe central hypovolemia. On the other hand, conventional echocardiographic indices appeared to deteriorate. Intriguingly, an index of LV filling (E/e’) was paradoxically enhanced during severe central hypovolemia.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A New Method Using the Four-Chamber View to Identify Fetuses With Subsequently Confirmed Postnatal Aortic Coarctation","authors":"Greggory R. DeVore,&nbsp;Bettina Cuneo,&nbsp;Gary Satou,&nbsp;Mark Sklansky","doi":"10.1111/echo.70092","DOIUrl":"https://doi.org/10.1111/echo.70092","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Objective&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To determine the sensitivity, specificity, and false-positive rate among fetuses suspected prenatally to have coarctation of the aorta (CoA) using size and shape measurements of the fetal heart from the four-chamber view (4CV).&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;This was a retrospective study of 108 fetuses identified by pediatric cardiologists to be at risk for CoA. 4CV s from the last antenatal ultrasound performed by the cardiologists were analyzed. The end-diastolic area was computed using the point-to-point trace method around the epicardial border of the 4CV, and the largest end-diastolic length and width were measured from the epicardium to the epicardium to compute the global sphericity index (GSI) (length/width). Using speckle tracking analysis, the ventricular end-diastolic area, length, basal and mid-chamber widths were measured. The sphericity index of the base and mid-chamber of the ventricles was computed (length/width). In addition, the end-diastolic area ratios were computed as follows: right ventricular area/4CV area and the left ventricular area/4CV area. The &lt;i&gt;z&lt;/i&gt;-scores for the above measurements were computed. Using logistic regression analysis, coefficients for predicting the probability of CoA from a test group of 27 fetuses with CoA and 27 without CoA was done. The logistic regression equation derived from the test group was applied to a validation group of 27 fetuses with CoA and 27 fetuses without CoA.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;The regression equation from the test group identified the following end-diastolic measurements: 4CV GSI, RV area/heart area, LV base SI, and the RV Base SI. The test group consisted of 14 of 27 fetuses with an isolated CoA (52%) and 13 of 27 (48%) with additional heart abnormalities. For the validation group, 10 of 27 (37%) had an isolated CoA, and 17 (63%) had additional cardiac abnormalities. Using the logistic regression equation derived from the test group (54 fetuses: 27 with CoA and 27 without CoA), the validation group (54 fetuses: 27 with CoA and 27 without CoA) demonstrated the following: sensitivity for detecting CoA of 98.15%, specificity 98.15%, and a false-positive rate of 1.85%. When the logistic regression was applied to the test group of fetuses with isolated CoA, 100% (14/14) were identified with logistic regression analysis. For the validation group, 9 of 10 (90%) of fetuses with isolated CoA were identified using the logistic regression equation.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Conclusions&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Using length, width, and area measurements of the 4CV and ventricles from which ratios are compu","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility Study of Applying the Modified Hahn Nomenclature for Tricuspid Valve Leaflet Classification in Transthoracic Echocardiography Using the Subxiphoid Short-Axis View","authors":"Hua Wang,&nbsp;Xiatian Liu,&nbsp;Zhelan Zheng,&nbsp;Bei Wang","doi":"10.1111/echo.70094","DOIUrl":"https://doi.org/10.1111/echo.70094","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aims to validate the feasibility of applying an adapted version of the Hahn tricuspid valve nomenclature to classify the leaflets of the tricuspid valve in the subxiphoid short-axis view (SSAV) using transthoracic echocardiography (TTE).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Referral patients from three medical institutions underwent TTE, with the requirement that the tricuspid valve structure be clearly visible in standard views (AC4 V, PSAV, RVIT, S4CV). The tricuspid valve leaflets were classified retrospectively based on the nomenclature proposed by Hahn et al.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Between June 2023 and June 2024, 600 patients' SSAV images were analyzed, with 421 cases (70.2%) successfully classified, while 179 cases (29.8%) failed to be classified. The average age of patients was 58 ± 31 years (range: 27–79 years). There were 334 males (55.7%). The mean weight was 75.7 ± 13.5 kg, and the average BMI was 23.1 ± 3.8 kg/m². Of the patients, 52.2% had mild or moderate tricuspid regurgitation (TR), 24.3% had severe TR, 22.8% had massive TR, and 2.3% had torrential TR. In the morphological classification of the tricuspid valve, type I was the most common (32.0%), followed by type IIIB (29.8%). Additionally, 179 cases (29.8%) were not successfully classified or determined.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>SSAV, as an adjunctive imaging view in TTE for assessing the tricuspid valve, shows potential clinical value. Although there are challenges in classifying tricuspid valve leaflets, the method demonstrates certain feasibility.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodality Imaging Approach for a Transient Ischemic Stroke as a First Manifestation of Papillary Fibroelastoma","authors":"Mariana Garcia-Villarejo,&nbsp;Diego Araiza Garaygordobil,&nbsp;Hector Gonzalez Pacheco,&nbsp;Hugo Gerardo Rodríguez Zanella,&nbsp;Alberto Aranda Faustro,&nbsp;Rodrigo Gopar Nieto,&nbsp;Maria Alexandra Arias-Mendoza,&nbsp;Jorge Daniel Sierra-Lara Martinez","doi":"10.1111/echo.70113","DOIUrl":"https://doi.org/10.1111/echo.70113","url":null,"abstract":"<p><b>Take home messages</b></p><p>1. Despite being considered a benign tumor, the high reported incidence of embolic events increasingly warrants surgical resection, regardless of size, especially in patients with a history of cardiovascular risk factors.</p><p>2. Multimodal imaging evaluation plays a crucial role in distinguishing intracardiac masses, relying on the physician's ability to discern characteristic findings. Proper assessment leads to appropriate management decisions based on suggestive findings.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Magnetic Resonance Imaging in Immune Checkpoint Inhibitor–Related Myocarditis","authors":"Matthew Hammer,&nbsp;Maciej Tysarowski,&nbsp;Cristina Fuss,&nbsp;Anna S. Bader","doi":"10.1111/echo.70131","DOIUrl":"https://doi.org/10.1111/echo.70131","url":null,"abstract":"<div>\u0000 \u0000 <p>Immune checkpoint inhibitors (ICIs) have revolutionized oncologic treatment, offering a novel and effective approach to personalized cancer immunotherapy. By targeting immune tolerance pathways, ICIs enhance T-cell-mediated tumor cytotoxicity. Despite their therapeutic efficacy, ICIs are associated with immune-related adverse events (irAEs), including severe cardiovascular complications like myocarditis, pericarditis, and vasculitis. ICI-related myocarditis, although uncommon, carries a high mortality rate of up to 50%, particularly in patients receiving combination therapies. This review examines the mechanisms of ICIs, highlights the clinical presentation of cardiac irAEs, and underscores the utility of cardiac magnetic resonance imaging (CMR) in the diagnosis of ICI-associated myocarditis. Through case studies, we illustrate the diagnostic and therapeutic strategies for ICI-related cardiac complications, highlighting the importance of multidisciplinary collaboration in mitigating morbidity and mortality.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breathless Nights: How Obstructive Sleep Apnea Affects the Right Heart","authors":"Ewa Majos-Karwacka","doi":"10.1111/echo.70126","DOIUrl":"https://doi.org/10.1111/echo.70126","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 3","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}