Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques最新文献

{"title":"Reverse Flow in the Glenn Anastomosis: What is Going on?","authors":"Daisy Chang, Corey Stiver, Amulya Buddhavarapu, Clifford L. Cua","doi":"10.1111/echo.70208","DOIUrl":"https://doi.org/10.1111/echo.70208","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144256007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Athlete's Heart in Women's Contact Sports: Echocardiographic and Strain-Based Insights From Elite Rugby Players","authors":"Çağatay Tunca,&nbsp;Saner Bahadır Gök,&nbsp;Ozan Güneş,&nbsp;Mehmet Taha Özkan,&nbsp;Alperen Taş,&nbsp;Ayşe Nur Özkaya İbiş,&nbsp;Yusuf Bozkurt Şahin,&nbsp;Murat Akdoğan,&nbsp;Ahmet Kıvrak,&nbsp;Kürşat Akbuğa,&nbsp;Veysel Ozan Tanık,&nbsp;Hatice Tolunay,&nbsp;Bülent Özlek","doi":"10.1111/echo.70218","DOIUrl":"https://doi.org/10.1111/echo.70218","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Athlete's heart encompasses cardiac adaptations to long-term intensive training. Although male-dominated sports have been widely studied, limited data exist on structural and functional cardiac remodeling in female contact-sport athletes. This study aimed to evaluate cardiac changes in elite female rugby players using conventional and strain echocardiography.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This cross-sectional study included 66 elite female rugby players and 50 sedentary controls. Anthropometric measurements and transthoracic echocardiographic assessments, including speckle tracking-derived global longitudinal strain (GLS), were performed. Linear, multivariable, and partial correlation analyses evaluated associations between GLS, active playing years (APY), and body mass index (BMI).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared to controls, athletes exhibited increased ventricular diameters, wall thicknesses, and left atrial size, with preserved left ventricular ejection fraction (LVEF). GLS values were significantly lower in rugby players (<i>p</i> &lt; 0.001), though within normal limits. APY and BMI both showed significant inverse correlations with GLS (<i>r</i> = –0.456 and −0.370, respectively). In multivariable analysis, APY (<i>β</i> = −0.392, <i>p</i> = 0.001) and BMI (<i>β</i> = −0.225, <i>p</i> = 0.013) independently predicted GLS. Partial correlation confirmed the independent association of APY with GLS (<i>r</i> = −0.412, <i>p</i> = 0.001). GLS showed strong discriminative performance for ≥5 years of play (AUC = 0.816) and moderate performance for BMI ≥ 24.13 (AUC = 0.666).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Elite female rugby athletes demonstrate physiological cardiac remodeling, including reduced GLS associated with training duration and BMI. These findings highlight the need for sex- and sport-specific echocardiographic reference values and further longitudinal research to clarify long-term clinical implications.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144245032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Acquisition to Prognosis: The Role of AI in Cardiac Magnetic Resonance Imaging Evaluation of Ischemic Cardiomyopathy","authors":"Giuseppe Muscogiuri,&nbsp;Nicola Pegoraro,&nbsp;Alberto Cossu,&nbsp;Alessandro Caruso,&nbsp;Davide Casartelli,&nbsp;Francesco Severi,&nbsp;Gabrielle Gershon,&nbsp;Marly van Assen,&nbsp;Carlo N De Cecco,&nbsp;Marco Guglielmo,&nbsp;Tommaso D'Angelo,&nbsp;Luca Saba,&nbsp;Riccardo Cau,&nbsp;Paolo Marra,&nbsp;Aldo Carnevale,&nbsp;Melchiore Giganti,&nbsp;Sandro Sironi","doi":"10.1111/echo.70201","DOIUrl":"https://doi.org/10.1111/echo.70201","url":null,"abstract":"<div>\u0000 \u0000 <p>Acute and chronic ischemic cardiomyopathy (ICM) still represents a leading cause of morbidity and mortality. Cardiac magnetic resonance (CMR) imaging plays a central role in the diagnosis and management of ICM, offering detailed visualization of cardiac structures and function. The evolving role of artificial intelligence (AI) in enhancing CMR exams, from acquisition to prognosis, is rapidly expanding in clinical practice, particularly in CMR of patients with ICM, emphasizing the integration of AI algorithms to optimize imaging workflows in standard protocols. Advanced AI models enable more efficient and faster image acquisition, reducing artifacts and enhancing accuracy, even offering free-breathing sequences. In post-processing, AI allows for the segmentation and quantification of cardiac parameters, facilitating precise assessment of volumes, myocardial scarring, and perfusion abnormalities, which are critical parameters in ICM. Moreover, AI-driven analysis provides robust prognostic insights by predicting adverse outcomes, such as heart failure and arrhythmias, through comprehensive data integration and pattern recognition. Looking forward, the future of AI in CMR promises further advancements in personalized medicine, with AI algorithms continually improving in accuracy and clinical applicability. This review will analyze the role of AI in increasing diagnostic accuracy, optimizing workflows, and improving prognosis in patients with ICM.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144244469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fusion Imaging and 3D Printing Tools to Improve Mitral Valve Interventions","authors":"Rafael Vidal-Perez,&nbsp;Alberto Bouzas-Mosquera,&nbsp;Jose Manuel Vazquez-Rodriguez","doi":"10.1111/echo.70217","DOIUrl":"https://doi.org/10.1111/echo.70217","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144244466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-Modality Imaging in Coronary Anomalies: Focus on Anomalous Aortic Origin of Coronary Arteries","authors":"Guglielmo Capponi,&nbsp;Biagio Castaldi,&nbsp;Domenico Sirico,&nbsp;Elena Reffo,&nbsp;Nadia Assanta,&nbsp;Giuseppe Santoro,&nbsp;Francesco Prati,&nbsp;Alice Pozza,&nbsp;Massimiliano Cantinotti,&nbsp;Giovanni Di Salvo","doi":"10.1111/echo.70213","DOIUrl":"https://doi.org/10.1111/echo.70213","url":null,"abstract":"<p>Coronary artery anomalies represent a series of congenital heart diseases characterized by the abnormal circulation of coronary arteries. Of particular interest is the anomalous aortic origin of coronary arteries (AAOCA), an underdiagnosed but potentially fatal anomaly, specifically relevant in young adult athletes. During the last decades, knowledge of the pathophysiology of AAOCA-related ischemic mechanisms has increased, and major risk conditions have been discovered. Unfortunately, a universally shared approach is still lacking, and clinicians often follow the policy of their own centers. Most of the population with AAOCA is asymptomatic or complains of minor symptoms but is among them that there is much more uncertainty about the correct strategy to perform a risk stratification process, and consequently for providing indications on exercise restriction or surgery. This review focuses on the diagnostic approach to coronary anomalies and discusses the diagnostic workflow in these patients. Finally, we perform an in-depth analysis of novel angiographic invasive functional methods and how they contribute to AAOCA in selected cases.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70213","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microalbuminuria Is Associated With Left Ventricular Systolic Function in Newly Diagnosed Hypertensive Patients","authors":"Selim Aydemir,&nbsp;Sidar Şiyar Aydın,&nbsp;Onur Altınkaya,&nbsp;Murat Özmen,&nbsp;Emrah Aksakal,&nbsp;İbrahim Halil Tanboğa","doi":"10.1111/echo.70216","DOIUrl":"https://doi.org/10.1111/echo.70216","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Hypertension (HT) is a significant disease and cardiovascular (CV) risk factor worldwide. In patients with HT, cardiac dysfunction constitutes the main problem. Urinary albumin creatinine ratio (UACR), a practical measurement for diagnosing microalbuminuria, is associated with adverse CV events in HT patients. Our study aimed to examine the relationships between UACR and cardiac functions in newly diagnosed HT patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Our study was designed prospectively. Patients diagnosed with HT were started on angiotensin-converting enzyme inhibitors (ACEIs) as treatment and were called for a follow-up after 3 months. Before and after treatment, spot urine samples, 24-h blood pressure monitoring, Conventional transthoracic echocardiography (TTE) parameters, and left ventricular global longitudinal strain (LVGLS) were calculated by Speckle-tracking echocardiography. A linear regression model evaluated the relationship between UACR and cardiac parameters measured on TTE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Our study consists of 104 patients diagnosed with HT. The mean age of the patients was 49.1 ± 9.5 years, and 44.2% were male. With treatment, mean, night, and day systolic blood pressure (SBP), pulse pressure, and arterial pressure decreased, and these decreases were significantly associated with UACR. Additionally, microalbuminuria decreased with treatment, and an independent and significant association was observed between the decrease in UACR and the improvement in LVGLS in linear regression analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In our study, a significant relationship was observed between microalbuminuria and LVGLS. It was observed that treatments that reduce microalbuminuria and blood pressure control in HT patients were associated with improvement in LV functions, and UACR, which shows microalbuminuria, may be useful in monitoring the improvement in LV systolic functions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144220066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Right Heart Assessment in Cancer Patients: Call to Action","authors":"Sivatharshini Ramalingam,&nbsp;Julia Toste,&nbsp;Konstantinos Papadopoulos,&nbsp;Kalliopi Keramida","doi":"10.1111/echo.70212","DOIUrl":"https://doi.org/10.1111/echo.70212","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Segmental Strain and Strain-Rate Imaging to Assess Cardiac Function in Patients With Limb-Girdle Muscular Dystrophy R9: An Observational Study of the Norwegian LGMDR9 Cohort","authors":"Safak Caglayan,&nbsp;Hatice Akay Caglayan,&nbsp;Synnøve M. Jensen,&nbsp;Kjell Arne Arntzen,&nbsp;Assami Rösner","doi":"10.1111/echo.70202","DOIUrl":"https://doi.org/10.1111/echo.70202","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Cardiomyopathy is a prevalent feature of limb-girdle muscular dystrophy R9 (LGMDR9), but its characterization remains incomplete. This study aims to assess cardiac function in patients with LGMDR9 using global and segmental myocardial function imaging.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A total of 42 participants (aged 23–71 years) from the Norwegian LGMDR9 cohort were compared with 97 controls (aged 40–69 years) from the Tromsø Study. Conventional and speckle tracking echocardiography were performed to assess cardiac function. Statistical analyses were adjusted for age and sex.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Patients with LGMDR9 had significantly reduced left ventricular ejection fraction (LVEF: 52.2% vs. 57.0%, <i>p &lt; </i>0.001) and decreased absolute global longitudinal strain (GLS: 17.6% vs. 20.5%, <i>p &lt; </i>0.001). Systolic dysfunction in patients was further observed by increased end-systolic left ventricular volume and internal diameter. Diastolic dysfunction was evident with reduced early to late ventricular filling velocities and further verified by decreased longitudinal strain-rate during early diastole (SR-E) and increased longitudinal strain-rate during atrial contraction (SR-A). Importantly, segmental analysis revealed region-specific differences in strain and strain-rate; mid and apical segments had decreased absolute strain, while basal segments remained largely unaffected. Notably, patients with normal LVEF also displayed decreased GLS (18.7% vs. 20.6%, <i>p &lt; </i>0.001) and regional and segmental alterations in strain and strain-rate.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We demonstrate that patients with LGMDR9 exhibit both systolic and diastolic dysfunction, primarily affecting the mid and apical myocardial segments. Strain and strain-rate imaging may serve as sensitive tools for early detection of myocardial dysfunction, and support clinical management and interventional studies in LGMDR9.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144206901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes of Prenatal Sonographic Vascular Parameters in Coarctation of the Aorta and the Risk Factors","authors":"Guihong Chen,&nbsp;Jie Mi,&nbsp;Yongfeng Han,&nbsp;Lu Qin,&nbsp;Yuanyuan Peng,&nbsp;Xuna Geng,&nbsp;Pei Zhou,&nbsp;Tianxiao Yu,&nbsp;Congxin Sun,&nbsp;Bu-Lang Gao,&nbsp;Shuping Ge","doi":"10.1111/echo.70210","DOIUrl":"https://doi.org/10.1111/echo.70210","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Purpose&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;To investigate changes in ultrasound vascular parameters in fetuses with coarctation of the aorta (CoA) and risk factors for CoA presence.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Materials and Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Fetuses of CoA and healthy controls without CoA confirmed after birth were prospectively enrolled. All ultrasound-related vascular parameters were analyzed.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Forty-five CoA positive fetuses and 336 age-matched (&lt;i&gt;p&lt;/i&gt; &gt; 0.05) healthy fetuses were enrolled. Compared with the normal fetuses, CoA positive fetuses exhibited significantly (&lt;i&gt;p&lt;/i&gt; &lt; 0.05) different ultrasound parameters. Significant (&lt;i&gt;p&lt;/i&gt; &lt; 0.05) independent risk factors of CoA presence were DA diameter, isthmus diameter at 3 vessel trachea view, arch diameter, left common carotid artery (LCCA) to left subclavian artery (LSA) distance, ascending aorta (AAO) diameter, and main pulmonary artery (MPA) diameter. The area under the receiver operating characteristics curve (AUC) and cutoff value were 0.997 and 0.395, respectively, for the overall fitted model &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mo&gt;(&lt;/mo&gt;\u0000 &lt;mi&gt;p&lt;/mi&gt;\u0000 &lt;mo&gt;=&lt;/mo&gt;\u0000 &lt;mn&gt;1&lt;/mn&gt;\u0000 &lt;mo&gt;/&lt;/mo&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mo&gt;[&lt;/mo&gt;\u0000 &lt;mn&gt;1&lt;/mn&gt;\u0000 &lt;mo&gt;+&lt;/mo&gt;\u0000 &lt;mi&gt;e&lt;/mi&gt;\u0000 &lt;mfrac&gt;\u0000 &lt;mrow&gt;\u0000 &lt;mo&gt;−&lt;/mo&gt;\u0000 &lt;mo&gt;(&lt;/mo&gt;\u0000 &lt;mn&gt;4.85&lt;/mn&gt;\u0000 &lt;mspace&gt;&lt;/mspace&gt;\u0000 &lt;mo&gt;+&lt;/mo&gt;\u0000 &lt;mspace&gt;&lt;/mspace&gt;\u0000 &lt;mn&gt;62.58&lt;/mn&gt;\u0000 &lt;mspace&gt;&lt;/mspace&gt;\u0000 &lt;mo&gt;×&lt;/mo&gt;\u0000 &lt;mspace&gt;&lt;/mspace&gt;\u0000 &lt;mtext&gt;DA diameter&lt;/mtext&gt;\u0000 &lt;mo&gt;−&lt;/mo&gt;\u0000 &lt;mn&gt;22.89&lt;/mn&gt;\u0000 &lt;mo&gt;×&lt;/mo&gt;\u0000 &lt;mtext&gt;isthmic diameter&lt;/mtext&gt;\u0000 &lt;mspace&gt;&lt;/mspace&gt;\u0000 &lt;mo&gt;−&lt;/mo&gt;\u0000 &lt;mn&gt;48.76&lt;/mn&gt;\u0000 &lt;mspace&gt;&lt;/mspace&gt;\u0000 &lt;mo&gt;×&lt;/mo&gt;\u0000 &lt;mspace&gt;&lt;/mspace&gt;\u0000 &lt;mtext&gt;arch segment 2 diameter&lt;/mtext&gt;\u0000 ","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144206902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complex Ventricular Arrhythmias in Patients with Mitral Annular Disjunction: A Systematic Review and Meta-Analysis","authors":"Lívian de S. Gonçalves,&nbsp;Luíza M. A. Tanus,&nbsp;Lucas A. Queiroz,&nbsp;Jonathan C. Dall'Acqua,&nbsp;Carlos Alberto Campello,&nbsp;Paula C. Nogueira","doi":"10.1111/echo.70211","DOIUrl":"https://doi.org/10.1111/echo.70211","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Mitral annular disjunction (MAD) frequently co-occurs with mitral valve prolapse (MVP). It is unclear, however, whether MAD is associated with an additional risk of arrhythmogenic events in patients with MVP. We aimed to evaluate the incidence of complex ventricular arrhythmias (VA) and sudden cardiac death (SCD) in patients with MAD compared to those without MAD.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We systematically searched PubMed, Embase, and Web of Science for studies evaluating the incidence of complex VA and the composite outcome of complex VA and SCD among patients with versus without MAD. We performed a random-effects meta-analysis to pool odds ratios (OR) and hazard ratios (HR) with 95% confidence intervals.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We included 16 studies comprising 6001 patients, of whom 23% had MAD; 41% were female; the mean age was 56.5 years. MVP was significantly present in both groups, with a higher prevalence in the MAD group in 1030 patients (74.5%) with MAD and in 1942 patients (47%) without MAD. The incidence of complex VA was significantly higher in patients with MAD (OR 3.88; 95% CI 1.69–8.93; <i>p</i> = 0.001), compared with patients without MAD. Patients with MAD also had a higher risk of the composite outcome of complex VA and SCD (HR 2.51; 95% CI 1.94–3.24; <i>p</i> &lt; 0.00001) (OR 3.13; 95% CI 1.38–7.11; <i>p</i> = 0.006).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In this meta-analysis, the presence of MAD was significantly associated with the development of complex VA and the composite outcome of complex VA and SCD. The outcome of SCD was not evaluated as an isolated endpoint.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 6","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}