Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques最新文献

{"title":"Neonatal Cardiac Rhabdomyoma: A Silent Dissolution","authors":"Jie Wang, Jun Xie, Ping Hu, Xiao-Jing Ma","doi":"10.1111/echo.70028","DOIUrl":"10.1111/echo.70028","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of 2, 4, and 5-dimensional Cardiac Flow MRI for Evaluation of Valvulopathies: A Literature Review","authors":"Sara Fässler,&nbsp;Mariana B. L. Falcão,&nbsp;Stefano F. de Marchi,&nbsp;Christopher W. Roy,&nbsp;Tobias Rutz","doi":"10.1111/echo.70005","DOIUrl":"10.1111/echo.70005","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>Two-dimensional phase-contrast magnetic resonance imaging (2D flow MRI) and its multidimensional alternatives, 4D and 5D flow MRI, measure blood flow in the heart and great vessels. While 2D flow MRI is the standard technique, it has limitations regarding need for precise image plane prescribing and long scan time. In contrast, 4D and 5D flow MRI acquire 3D volumes, enabling retrospective assessment of all vessels. This review evaluates these three techniques for quantification of blood flow of the aortic and pulmonary valves in congenital heart disease.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A systematic literature search was conducted in August 2024 using the PUBMED database, including articles comparing 2D, 4D, and 5D flow MRI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifteen articles comparing 2D and 4D, one comparing 2D and 5D and three articles comparing 4D and 5D flow MRI were included. No study compared all three techniques. 2D, 4D and 5D flow MRI demonstrated a good agreement for flow quantification. 4D flow MRI, however, tends to present a better accuracy and internal consistency than 2D flow MRI for determination of peak velocities and flow in stenotic lesions, particularly when comparing velocities to echocardiography. 4D and 5D flow MRI are associated with shorter scan times than 2D flow MRI.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>4D and 5D flow MRI appear to offer promising alternatives to 2D flow MRI with the advantage of reduced scan times. Larger and prospective studies including echocardiography are needed to evaluate the potential of 4D and 5D to replace 2D flow MRI for flow quantification and peak velocity determination.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Noninvasive Prediction Model With Simple Echocardiographic Variables for Shunts Closure Possibility in Patients With Posttricuspid Valve Shunt Defect","authors":"Hezhi Li,&nbsp;Zehan Huang,&nbsp;Zhengan Huang,&nbsp;Xiaoshan Li,&nbsp;Caojin Zhang,&nbsp;Hongwen Fei","doi":"10.1111/echo.70016","DOIUrl":"10.1111/echo.70016","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>As right heart catheterization (RHC) is invasive and not always accessible, this study developed a noninvasive model (P-echo) to predict shunt closure feasibility in adult congenital heart disease (ACHD) patients with post-tricuspid valve shunt defects (PTD), specifically isolated ventricular septal defects (VSD) and patent ductus arteriosus (PDA).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis of 1474 VSD or PDA patients from 2012 to 2022 was conducted. Echocardiographic parameters were assessed, and key variables identified via LASSO regression. The P-echo model incorporated left to right velocity (LRv), right to left velocity (RLv), tricuspid regurgitation (TR), pulmonary artery diameter (PA), and RV/LV ratio. Its predictive performance was evaluated using ROC curve analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The P-echo model demonstrated excellent predictive performance with AUC values of 0.975 (95% CI: 0.965–0.984) in the derivation set, 0.963 (95% CI: 0.937–0.989) in the validation set, and high accuracy in both PDA (AUC 0.975, 95% CI: 0.965–0.984) and VSD (AUC 0.958, 95% CI: 0.936–0.980) subsets. In the derivation set, the model categorized patients into low (9.1% closure rate), medium (70.9% closure rate), and high-risk groups (99.7% closure rate) for shunt closure feasibility. Calibration plots confirmed the model's accuracy. Decision curve analysis showed a higher net benefit across a range of threshold probabilities, indicating the clinical usefulness of the model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The P-echo model is a robust and reliable tool for predicting the feasibility of shunt closure in patients with PTD, offering a noninvasive alternative to RHC. This model can guide clinical decision-making and support individualized treatment strategies in ACHD management.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Validation of an Individualized Nomogram for Predicting Patent Foramen Ovale-Associated Stroke: Patent Foramen Ovale Morphology-Based Analysis","authors":"Qin Zhang,&nbsp;Mochao Xiao,&nbsp;Wuzhu Lu,&nbsp;Yuhong Lin,&nbsp;Ziqing Gao,&nbsp;Yuzhuo Chen,&nbsp;Jiali Tian,&nbsp;Zhongzhen Su,&nbsp;Xiaobo Chen","doi":"10.1111/echo.15932","DOIUrl":"10.1111/echo.15932","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>We previously reported four patent foramen ovale (PFO) morphological types that influenced right-to-left shunt (RLS) grades. Herein, we aimed to study the relationship between PFO morphology and cryptogenic stroke (CS). We further developed a nomogram based on four PFO morphological types and functional parameters to guide clinicians in judging the risk of PFO-associated stroke.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This was a retrospective observational study involving adult patients with PFO between January 2020 and November 2022. Patients were divided into a PFO-associated stroke group (CS group) and a group without cryptogenic stroke (non-CS group). Four types of PFO and RLS grades were analyzed. Nomograms were made to predict PFO-associated stroke using multivariable logistic regression analysis. The discrimination performance of the model was internally validated and assessed using the receiver operating characteristic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We enrolled 389 patients (male, 182 patients; female, 207 patients) with PFO, the mean age was 43.3 ± 8.1 years. The derivation cohort comprised 293 patients (CS group, 186 patients; non-CS group, 107 patients). The predictive nomogram comprised PFO morphological types, interatrial septum (IAS) mobility distance, septum primum thickness, PFO channel length at rest, and contrast-transthoracic echocardiography (c-TTE) RLS grade during the Valsalva maneuver. A validation cohort was established (CS group, 61 patients; non-CS group, 35 patients). The model area under the curve (AUC) was 0.891 (95% confidence interval = 0.855−0.928) in the derivation cohort and 0.935 (95% confidence interval = 0.885−0.986) in the validation cohort. Calibration curve analysis showed that the nomogram had a C-index of 0.891 in the derivation cohort and 0.935 in the validation cohort. The decision curve analysis (DCA) indicated that the nomogram had clinical applicability.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Adding four PFO morphological types improved the risk stratification capability for PFO-associated stroke. The nomogram can identify high or low-risk PFO individuals and select patients who will likely benefit from interventional device closure.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Follow-Up Study of Percutaneous Intramyocardial Septal Radiofrequency Ablation in the Treatment of Hypertrophic Obstructive Cardiomyopathy With HFpEF","authors":"Chang Wang,&nbsp;Weitao Guo,&nbsp;Huican Duan,&nbsp;Junchang Qin,&nbsp;Fangming Wang,&nbsp;Tianyu He,&nbsp;Lu Gao,&nbsp;Zhengyang Han,&nbsp;Ruifang Zhang,&nbsp;Lina Wu","doi":"10.1111/echo.15930","DOIUrl":"10.1111/echo.15930","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The study aimed to evaluate the changes of left ventricular diastolic function and the improvement of clinical symptoms in hypertrophic cardiomyopathy (HCM) patients with heart failure with preserved ejection fraction (HFpEF) after percutaneous intramyocardial septal radiofrequency ablation (PIMSRA).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study enrolled 31 adult HCM patients with HFpEF who underwent PIMSRA treatment. Electrocardiogram, imaging, and blood biochemical examinations were performed on these patients during a 6-month follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Compared with the baseline, at 6 months after PIMSRA, patients showed significant reductions in peak left ventricular outflow tract pressure gradients (resting gradient: from a mean of 83.24 to 23.40 mmHg, <i>p</i> &lt; 0.001; postexercise gradient: from a mean of 109.70 to 33.39 mmHg, <i>p</i>&lt; 0.001). The interventricular septal thickness reduced from a mean of 22.90 to 17.48 mm, <i>p</i> &lt; 0.001. The E/e’ decreased from a median of 18.67 to 11.54, <i>p</i> &lt; 0.001. The 6-minute walk distance (6MWD) increased from a mean of 359.03 to 435.81 m, <i>p</i> &lt; 0.001. The Kansas City Cardiomyopathy Questionnaire Overall Summary Score (KCCQ OS) increased from a mean of 57.57 to 71.93, <i>p</i> &lt; 0.001. The number of HFpEF patients diagnosed according to the European Society of Cardiology's Heart Failure Association HFA-PEFF score decreased from 31 to 23. None of the patients had new-onset bundle branch block or complete heart block after PIMSRA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>PIMSRA is a safe and effective treatment. It can improve left ventricular diastolic function and quality of life in HCM patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Speckle-Tracking Echocardiography as an Effective Screening Tool for Cardiac Involvement Among Patients With Systemic Sarcoidosis in an Indian Cohort: A Prospective Observational Study","authors":"Prasanth Areekkara Poduvattil,&nbsp;Zia Hashim,&nbsp;Sudeep Kumar,&nbsp;Neeraj Jain,&nbsp;Manish Ora,&nbsp;Sanjay Gambhir,&nbsp;Mansi Gupta,&nbsp;Ajmal Khan,&nbsp;Alok Nath,&nbsp;Vinita Agrawal","doi":"10.1111/echo.15957","DOIUrl":"10.1111/echo.15957","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Diagnosing cardiac sarcoidosis (CS) is challenging due to the lack of a sensitive gold standard diagnostic test. Although advanced imaging techniques like cardiac magnetic resonance imaging (MRI) (cardiovascular magnetic resonance [CMR]) and fluorodeoxyglucose positron emission tomography (FDG-PET) CT are promising, they are limited by their availability and cost. Two-dimensional speckle-tracking echocardiography (2D-STE) is emerging as a valuable tool for the early detection of CS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This single-center observational study assessed cardiac involvement and the utility of STE as a screening tool for diagnosing CS among newly diagnosed, histologically confirmed, treatment-naïve patients with systemic sarcoidosis in an Indian cohort.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study included 48 newly diagnosed sarcoidosis patients with a median age of 42.5 years (interquartile range [IQR] 34–53.5), of whom 52.1% were female. FDG-PET CT findings suggested cardiac involvement in 21 patients, while CMR findings were positive in 11 patients. All patients had normal 12-lead ECGs and echocardiograms. Twenty-five patients met the HRS 2014 criteria for CS diagnosis. The median (IQR) left ventricular global longitudinal strain (LV GLS) was −15.4 (−16.2, −13.4) in the probable CS group and −17.9 (−19.4, −17.4) in the non-CS group. An LV GLS cutoff of &gt;−17.3 showed a sensitivity of 80.00% and a specificity of 82.61% (<i>p</i> &lt; 0.001, area under the curve [AUC] = 0.790) for CS diagnosis. A right ventricular global longitudinal strain (RV GLS) cutoff of &gt;−21.4 showed a sensitivity of 68.00% and a specificity of 78.26% (<i>p</i> &lt; 0.017, AUC = 0.692). They both have very high negative predictive value (98.7% and 97.9%) and thus useful for ruling out the cardiac involvement than confirming it.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>STE effectively screens for cardiac involvement in sarcoidosis patients, ruling out CS diagnosis.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Looking at Early Systolic Dysfunction in Chronic Kidney Disease: What's Next?","authors":"Andrea Faggiano,&nbsp;Elisa Gherbesi,&nbsp;Cesare Cuspidi","doi":"10.1111/echo.70024","DOIUrl":"10.1111/echo.70024","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Evolving Science on Sudden Cardiac Death—The Marriage of Left Ventricular Hypertrophy and QT-Dispersion","authors":"James Ker","doi":"10.1111/echo.70026","DOIUrl":"10.1111/echo.70026","url":null,"abstract":"&lt;p&gt;The first description of sudden cardiac death was made by Hippocrates in the 4th century BC [&lt;span&gt;1&lt;/span&gt;]. Such cases of sudden collapse and death have intrigued both the public and medical science for centuries and a practical definition is that sudden cardiac death is the unexpected and natural death from a cardiac cause within a short period, usually less than 1 h from the onset of symptoms, in a person without any known prior condition [&lt;span&gt;1, 2&lt;/span&gt;]. Sudden cardiac death (SCD) is clearly the end-result of a wide variety of cardiac conditions—both congenital and acquired. However, the most common mechanism for the event of SCD is ventricular fibrillation [&lt;span&gt;1&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Understandably, SCD can afflict both the athlete and the non-athlete and is the cause of 13%–20% of all deaths in Western countries [&lt;span&gt;2&lt;/span&gt;]. In athletes older than 35 years of age atherosclerotic coronary artery disease is the most common cause of SCD, while primary cardiomyopathies and ion channelopathies are more commonly found in the young athlete with SCD [&lt;span&gt;2&lt;/span&gt;]. However, this is an evolving field of study and the recent study published by Stojanovic et al. [&lt;span&gt;3&lt;/span&gt;] is of great importance as it links two well-known risk factors for SCD—left ventricular hypertrophy (LVH) and QT-dispersion [&lt;span&gt;4&lt;/span&gt;]. The strong association between LVH and overall cardiovascular mortality first emerged from the Framingham heart study [&lt;span&gt;4&lt;/span&gt;]. Initially, after this observation, several studies have confirmed the strong association between LVH and cardiovascular mortality, but the specific association with sudden cardiac death (SCD) came later with the Oregon Sudden Unexpected Death Study (Oregon SUDS)–one of the first to confirm the link between LVH and SCD [&lt;span&gt;4, 5&lt;/span&gt;]. The development of LVH creates various pathways to ventricular arrhythmogenesis, which include ventricular ectopy, in fact, every additional millimeter of left ventricular wall thickness increases the risk of ventricular ectopy 2- to 3-fold [&lt;span&gt;4&lt;/span&gt;]. LVH is the cause of significant cellular and interstitial remodeling of the myocardium which promotes ventricular arrhythmogenesis from both re-entry and triggered activity [&lt;span&gt;4&lt;/span&gt;]. An increase in left ventricular mass (LVH) results in various myocardial alterations resulting in electrical remodeling with resultant prolonged QRS intervals, prolonged OT intervals, interstitial fibrosis with re-entry, sub-endocardial ischemia and increased sensitivity to pro-arrhythmia due to an increase in left ventricular wall stress [&lt;span&gt;4&lt;/span&gt;]. In fact, all forms of left ventricular hypertrophy, concentric, eccentric, and even concentric remodeling without hypertrophy are all associated with an increased risk for sudden cardiac death [&lt;span&gt;6&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;The QT interval—the interval from the beginning of the QRS complex to the end of the T wave on the surface ECG—represents the period of global ventricu","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Heterogeneous Plaque Deposition on Computed Tomography Derived Fractional Flow Reserve","authors":"Toshimitsu Tsugu,&nbsp;Kaoru Tanaka,&nbsp;Yuji Nagatomo,&nbsp;Mayuko Tsugu,&nbsp;Johan De Mey","doi":"10.1111/echo.70025","DOIUrl":"10.1111/echo.70025","url":null,"abstract":"<p>L/P ratio, which indicates the proportion of lumen volume to plaque volume of the vessel, is lower in lesion than in per-lesion (RCA, 0.9 vs. 7.7; LAD, 1.4 vs. 8.1; and LCX, 0.9 vs. 8.0). For lesion located in the middle segments of the three major vessels, FFR_CT drops from 0.97 to 0.78 for RCA, from 0.94 to 0.55 for LAD, and from 0.99 to 0.72 for LCX, respectively. Invasive coronary angiography shows moderate stenosis in the middle segment of the RCA but no significant obstructive coronary disease at the sites where FFR_CT showed a substantial decline in the LAD and LCX. CCTA indicates coronary CT angiography; ICA, invasive coronary angiography; LAD, left anterior descending artery; LCX, left circumflex artery; RCA, right coronary artery; SOCAD, significant obstructive coronary disease.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Microvascular Dysfunction: Searching the Strongest Imaging Modality in Different Scenarios","authors":"Mollace Rocco,&nbsp;Nicoli Flavia,&nbsp;Licastro Margherita,&nbsp;Maria Lo Monaco,&nbsp;Elona Collaku,&nbsp;Alessandro Nudi,&nbsp;Alessandro Gad,&nbsp;Cristina Procopio,&nbsp;Annamaria Ioppolo,&nbsp;Erika Bertella","doi":"10.1111/echo.70022","DOIUrl":"10.1111/echo.70022","url":null,"abstract":"<div>\u0000 \u0000 <p>Coronary microvascular dysfunction is a clinical condition very diffuse in many different settings. Often the diagnosis can be very tricky, and choosing the proper diagnostic strategy can be fundamental for reaching the goal. The aim of this review is to evaluate the properties and the feasibility of our tests in specific scenarios by looking at the performances of each methodology reported in the literature.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"41 11","pages":""},"PeriodicalIF":1.6,"publicationDate":"2024-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}