{"title":"Risk Stratification of Left Ventricle Hypertrabeculation Versus Non-Compaction Cardiomyopathy Using Echocardiography, Magnetic Resonance Imaging, and Cardiac Computed Tomography","authors":"Marianna Mirchuk","doi":"10.1111/echo.70165","DOIUrl":"https://doi.org/10.1111/echo.70165","url":null,"abstract":"<div>\u0000 \u0000 <p>Non-compaction cardiomyopathy (NCCM) is a rare, congenital form of cardiomyopathy characterized by excessive trabeculations in the left ventricle myocardium. NCCM is often an underdiagnosed heart condition characterized by abnormal myocardial trabeculations, which can lead to a wide range of clinical outcomes, from asymptomatic cases to severe heart failure and arrhythmias. It is often diagnosed using imaging techniques like echocardiography, cardiac magnetic resonance imaging (CMR), and cardiac computed tomography (CT), which help assess the heart's structure and function. Although echocardiography remains a key tool, CMR is a gold standard for left ventricle NCCM diagnosis, structural and functional assessment, accurate trabecular quantification, detects fibrosis with late gadolinium enhancement, superior in risk stratification for sudden cardiac death. CT has gained importance in diagnosing NCCM, especially in ruling out coronary artery disease and evaluating complications such as left ventricle thrombus. Accurate risk stratification is crucial for identifying high-risk patients and providing timely interventions. This review examined the contributions of echocardiography, CMR, and cardiac CT in diagnosing NCCM, assessing disease severity, and guiding treatment decisions. We highlighted the strengths and limitations of each imaging modality, discussing their ability to detect myocardial abnormalities, evaluate heart function, and identify fibrosis or other structural changes. We also emphasized integrating imaging findings with clinical and genetic data to enhance patient management and outcomes. Finally, we explored the potential future applications of artificial intelligence in improving diagnostic accuracy and refining risk assessment in NCCM.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute Evolution of the Aortic Root Mass","authors":"Xin Wei, Bingjie Li, Hong Tang, Yujia Liang","doi":"10.1111/echo.70176","DOIUrl":"https://doi.org/10.1111/echo.70176","url":null,"abstract":"<p>A 67-year-old male with severe bicuspid aortic stenosis (BAS), who had declined surgical intervention one year prior, presented with progressive dyspnea requiring hospitalization. Serial echocardiographic examinations revealed acute evolution of an aortic root abscess, which demonstrated the particular process of the disease transformation.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143892832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edgar Francisco Carrizales-Sepúlveda, Eduardo Hernández-Rangel, Alejandro Ordaz-Farías
{"title":"A Deeper Dive Into the Myocardium for the Detection of Cancer Therapy-Related Cardiac Dysfunction: Radiomics in Cardio-Oncology","authors":"Edgar Francisco Carrizales-Sepúlveda, Eduardo Hernández-Rangel, Alejandro Ordaz-Farías","doi":"10.1111/echo.70174","DOIUrl":"https://doi.org/10.1111/echo.70174","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143888840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peter L. M. Kerkhof, Elena-Laura Antohi, Serban Mihaileanu
{"title":"How to Evaluate MADness Concerning the Valvular Apparatus?","authors":"Peter L. M. Kerkhof, Elena-Laura Antohi, Serban Mihaileanu","doi":"10.1111/echo.70173","DOIUrl":"https://doi.org/10.1111/echo.70173","url":null,"abstract":"<p>Survey of factors and metrics involved in progression of mitral annulusdisjunction (MAD). At two levels there is clear interaction between the leftatrium (LA) and left ventricle (LV), manifest as mechanical/hemodynamic andelectrical signal transmission properties. LGE = late gadolinium enhancement. Future research should concentrate on the course of the clinical consequences, rather than on an almost unobservable MAD.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143888839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Danton Machado da Cunha, Mauro Felippe Felix Mediano, Lorena dos Santos Marreto Rimolo, Andréa Rodrigues da Costa, Danilo Bento Diogo, Luiz Henrique Conde Sangenis, Henrique Horta Veloso, Marcelo Teixeira de Holanda, Alejandro Marcel Hasslocher-Moreno, Ademir Batista da Cunha, Roberto Magalhães Saraiva
{"title":"Predictors of Incident Heart Failure in Patients With Chronic Chagas Disease Cardiomyopathy","authors":"Danton Machado da Cunha, Mauro Felippe Felix Mediano, Lorena dos Santos Marreto Rimolo, Andréa Rodrigues da Costa, Danilo Bento Diogo, Luiz Henrique Conde Sangenis, Henrique Horta Veloso, Marcelo Teixeira de Holanda, Alejandro Marcel Hasslocher-Moreno, Ademir Batista da Cunha, Roberto Magalhães Saraiva","doi":"10.1111/echo.70163","DOIUrl":"https://doi.org/10.1111/echo.70163","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>Patients with chronic Chagas cardiomyopathy (CCC) have a high mortality due to heart failure (HF). The aim of this study was to investigate clinical and echocardiographic predictors of incident HF in patients with CCC.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Single-center retrospective longitudinal observational study which included 176 adult patients (59.1% women; 53.9 ± 10 years old; mean left ventricular [LV] ejection fraction 62% ± 10%) at an early stage of CCC (electrocardiogram and/or wall motion changes but no HF). The primary outcome was incident HF. The association between studied parameters with incident HF was performed by competing-risk survival regression models using the Fine and Gray method.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>After a mean follow-up of 8.8 ± 3.6 years, 42 patients progressed to HF (27.04 cases/1000 patient-years). A model 0 adjusted for clinical and 2D-Doppler echocardiographic parameters and for all-cause mortality revealed diabetes mellitus (HR 4.91, 95% CI 1.67–14.4, <i>p</i> = 0.004), LV ejection fraction (HR 0.96, 95% CI 0.93–0.99, <i>p</i> = 0.022), and E’ velocity (HR 0.79, 95% CI 0.67–0.95, <i>p</i> = 0.01) as independently associated with incident HF. The addition of strain-derived parameters to model 0 revealed that LV global circumferential strain (HR 0.83, 95% CI 0.78–0.89, <i>p</i> < 0.001) and left atrial booster contraction strain (HR 1.14, 95% CI 1.02–1.28, <i>p</i> = 0.022) were associated with incident HF.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>While most clinical parameters were not associated with incident HF in patients with CCC, echocardiographic parameters, including LV systolic and diastolic function and strain-derived parameters, were associated with incident HF in patients with CCC. This knowledge can be very useful for planning the care and follow-up of these patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143884130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robert W. Loar, Ricardo H. Pignatelli, J. Christopher Wilkinson, Christopher R. Broda, John L. Colquitt
{"title":"Strain Measures of Atrial and Ventricular Diastolic Function in Pediatric Fontan Patients: Comparisons to Controls and Between Ventricular Morphology Types","authors":"Robert W. Loar, Ricardo H. Pignatelli, J. Christopher Wilkinson, Christopher R. Broda, John L. Colquitt","doi":"10.1111/echo.70133","DOIUrl":"https://doi.org/10.1111/echo.70133","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Fontan patients may have abnormal diastolic function, but this is poorly characterized using conventional echocardiography. Herein, we describe atrial function and other diastolic strain measurements in a cohort of pediatric Fontan patients, with comparisons to healthy controls and between right ventricle (RV) and left ventricle (LV) types.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This is a single-institution, cross-sectional study of healthy controls (<i>n</i> = 50) and patients with a Fontan circulation (<i>n</i> = 50, 29 RV type, 21 LV type). Parameters of atrial function and ventricular systolic and diastolic function derived from speckle-tracking echocardiography (STE) were retrospectively obtained from apical four-chamber images. These included three phases of atrial strain (Ɛ) and strain rate (SR): contraction (ac), conduit (con), and reservoir (res), and diastolic SR for passive (E-SR) and active (A-SR) filling.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fontan patients had lower Ɛcon (13.4% vs. 28.2%, <i>p</i> < 0.01) and Ɛres (22.8% vs. 37.7%, <i>p</i> < 0.01) compared to controls. They had a longer time to peak atrial filling (450 ms vs. 399 ms, <i>p</i> < 0.01) and a greater reliance on atrial contraction for ventricular filling (atrial contraction fraction 41% vs. 26%, <i>p</i> < 0.01). RV type Fontan patients had longer time to peak atrial filling (461 ms vs. 406 ms, <i>p</i> = 0.02) and lower E-SR (1.0 %/s vs. 1.4%/s, <i>p</i> = 0.01) compared to LV type.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Several atrial and diastolic strain parameters in pediatric Fontan patients are altered compared to controls. Additionally, some metrics are more deranged in RV type Fontan patients. This highlights the need for population-specific normal values in patients with a Fontan circulation. Study of the clinical correlations and prognostic value of these STE-derived parameters is also warranted.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143875534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Musa Öztürk, İlker Ertuğrul, Şafak Alpat, Mustafa Yılmaz, Tevfik Karagöz
{"title":"Born to be Bad: Combination of Aorticopulmonary Window With Double-Outlet Right Ventricle-Pulmonary Atresia","authors":"Musa Öztürk, İlker Ertuğrul, Şafak Alpat, Mustafa Yılmaz, Tevfik Karagöz","doi":"10.1111/echo.70170","DOIUrl":"https://doi.org/10.1111/echo.70170","url":null,"abstract":"<p>Pulmonary atresia is a rare and complex congenital cardiac condition accompanied by an aortopulmonary window (APW) and double-outlet right ventricle (DORV). Here, we describe a case of a newborn with DORV, ventricular septal defect (VSD), pulmonary atresia, and APW. The patient underwent successful postnatal evaluation and echocardiography, revealing significant anomalies, including a large AP window providing pulmonary blood flow. The coexistence of DORV with pulmonary atresia and APW emphasizes the complexity of managing such congenital heart diseases, necessitating a multidisciplinary approach for optimal outcomes.</p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143875532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Li Zhao, Yunchuan Ding, Yu Zhang, Xuan Su, Qinghui Wang
{"title":"Chiari Network-Induced Tricuspid Valve Obstruction","authors":"Li Zhao, Yunchuan Ding, Yu Zhang, Xuan Su, Qinghui Wang","doi":"10.1111/echo.70171","DOIUrl":"https://doi.org/10.1111/echo.70171","url":null,"abstract":"<div>\u0000 \u0000 <p>We present a case of a 5-day-old neonate exhibiting lip cyanosis and hypoxemia, with a percutaneous oxygen saturation of 74%, as the primary clinical manifestations. Echocardiography and intraoperative examination revealed an abnormally elongated Chiari network obstructing the tricuspid valve orifice. This case highlights the clinical importance of anatomical variations in the Chiari network, which, although generally a benign embryological remnant, can lead to hemodynamic disturbances necessitating prompt identification in neonatal cardiology assessments.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 5","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143875533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is It Possible to Detect the Pathogenesis of Cardiac Amyloidosis by Echocardiography?","authors":"Yuko Fukuda","doi":"10.1111/echo.70169","DOIUrl":"https://doi.org/10.1111/echo.70169","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143865689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sara Seitun, Cesare Mantini, Alberto Clemente, Virginia Sambuceti, Giulia Francese, Sara Carpaneto, Roberta Della Bona, Giuseppe Mascia, Giuseppe Cittadini, Italo Porto
{"title":"Role of CT and CMR in the Management of Chronic Coronary Syndrome","authors":"Sara Seitun, Cesare Mantini, Alberto Clemente, Virginia Sambuceti, Giulia Francese, Sara Carpaneto, Roberta Della Bona, Giuseppe Mascia, Giuseppe Cittadini, Italo Porto","doi":"10.1111/echo.70117","DOIUrl":"https://doi.org/10.1111/echo.70117","url":null,"abstract":"<div>\u0000 \u0000 <p>Chronic coronary syndrome (CCS), encompassing a wide range of phenotypes and clinical scenarios, remains the leading global cause of disability and premature death. Advanced non-invasive imaging modalities, such as coronary computed tomography angiography (CCTA) and cardiac magnetic resonance (CMR), play a pivotal role in enhancing diagnostic accuracy and guiding tailored management strategies for CCS patients. CCTA offers detailed insights into the presence, extent, and severity of coronary atherosclerotic plaques. In addition to detecting coronary stenoses, it enables the characterization of plaque phenotypes and the evaluation of additional prognostic biomarkers, such as perivascular adipose tissue (PVAT) attenuation, allowing for more comprehensive risk stratification. Recent technological advancements have further expanded CCTA's capabilities, enabling the integration of anatomical assessment with hemodynamic evaluation through non-invasive fractional flow reserve computation (FFR-CT) or stress myocardial perfusion analysis. With its superior three-dimensional spatial resolution, CCTA enhances pre-procedural planning for complex coronary revascularization, enabling the selection of optimal interventional strategies and improving patient selection. CMR is considered the gold standard for functional assessment of cardiac function, myocardial viability, quantitative flow evaluation, and tissue characterization, offering excellent soft-tissue contrast. CMR perfusion imaging can accurately assess myocardial ischemia, quantify myocardial blood flow (MBF), and detect microvascular dysfunction, thanks to its high temporal and spatial resolution with the advantage of no radiation exposure. This review highlights the evolving role of CCTA and CMR in managing patients with CCS, focusing on their current applications according to the most recent 2024 ESC guidelines, prognostic value, and recent technological advancements.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 4","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143871468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}