Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques最新文献

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Effects of Electrode Thickness on Tricuspid Regurgitation and Radiation Exposure in Single-Chamber Implantable Cardioverter Defibrillators 电极厚度对单室植入式心律转复除颤器三尖瓣返流和辐射暴露的影响
IF 1.4 4区 医学
Fatih Gülçebi, Ahmet Özderya, İsmet Durmuş, Muhammet Raşit Sayın
{"title":"Effects of Electrode Thickness on Tricuspid Regurgitation and Radiation Exposure in Single-Chamber Implantable Cardioverter Defibrillators","authors":"Fatih Gülçebi,&nbsp;Ahmet Özderya,&nbsp;İsmet Durmuş,&nbsp;Muhammet Raşit Sayın","doi":"10.1111/echo.70275","DOIUrl":"https://doi.org/10.1111/echo.70275","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Currently, cardiac devices are widely used, and the effects of the electrodes of these devices on the tricuspid valve are being investigated. This study aimed to prospectively investigate, using two-dimensional echocardiography, the impact of electrode thickness on the development of tricuspid regurgitation (TR) and operator radiation exposure during the implantation of single-chamber implantable cardioverter-defibrillators (VVI-ICDs).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This prospective study included 61 patients treated at a single center between March 2023 and January 2024. Among these, 31 patients received 9F electrodes, and 30 patients received 7F electrodes. Initial echocardiographic evaluation was conducted 1 day before device implantation (T0). Follow-up evaluations were performed 1 day (T1) and 1 month (T2) after implantation. Tricuspid regurgitation was assessed using two-dimensional (2D) echocardiography and classified into grades 1–4 based on vena contracta and proximal isovelocity surface area measurements. A worsening of TR by one grade or more was deemed significant. Electrode implantation times and radiation doses were recorded during the procedures. At the 1-month follow-up, device interrogation was performed, and pacing percentages were documented.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Baseline echocardiographic parameters were comparable between the two groups. No significant TR worsening was observed at T1 in either group (<i>p</i> = 1.00). At T2, TR worsening was significantly more prevalent in the 9F group (<i>p</i> = 0.033). However, the 7F group demonstrated significantly longer electrode implantation times (<i>p</i> = 0.014) and higher total radiation exposure (<i>p</i> = 0.011). No deterioration in right heart function was observed in either group during the 1-month follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The use of thinner electrodes in VVI-ICD implantation may reduce electrode-related TR worsening. However, thinner electrodes are more challenging to implant, resulting in prolonged procedure times and increased radiation exposure for the operator. Further large-scale prospective studies are needed to confirm these findings.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 9","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Changes in Mitral Annular Geometry After Transcatheter Edge-to-Edge Repair With PASCAL 经导管边缘对边缘修复后二尖瓣几何形状的急性改变
IF 1.4 4区 医学
Konstantinos Papadopoulos, Michael Chrissoheris, Dionysios Aravantinos, Ignatios Ikonomidis, Konstantinos Spargias, Mani A. Vannan
{"title":"Acute Changes in Mitral Annular Geometry After Transcatheter Edge-to-Edge Repair With PASCAL","authors":"Konstantinos Papadopoulos,&nbsp;Michael Chrissoheris,&nbsp;Dionysios Aravantinos,&nbsp;Ignatios Ikonomidis,&nbsp;Konstantinos Spargias,&nbsp;Mani A. Vannan","doi":"10.1111/echo.70279","DOIUrl":"https://doi.org/10.1111/echo.70279","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Transcatheter edge-to-edge mitral valve repair (TEER) is an effective and safe method for treating high-risk patients with severe mitral regurgitation (MR). Two approved devices, MitraClip (Abbott Vascular) and PASCAL (Edwards Lifesciences), use leaflet approximation to reduce MR and may also influence annular dimensions via leaflet tension. The purpose of this study is to analyze the acute mitral annular dimensional changes following PASCAL implantation and correlate with long-term results.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A retrospective analysis was conducted on 115 high-risk patients (mean age 76 ± 11 years) with moderate-to-severe and severe MR (grade 3.9 ± 0.3, EROA 49± 23 mm<sup>2</sup>, LV ejection fraction 47% ± 14%). All patients had elevated surgical risk scores (logistic EuroSCORE 23.6% ± 11.5%, EuroSCORE II 6.9% ± 5%, STS Score 5.5± 4.2). Intraprocedural transesophageal echocardiography (TOE) was post-analyzed using specialized software to assess mitral annular geometry.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>PASCAL effectively reduced MR (grade 3.9 ± 0.3 to 1.2 ± 0.5, <i>p </i>&lt; 0.001) in all patients. Significant reductions in 3D annulus area (15 ± 4cm<sup>2</sup> to 13.9 ± 4cm<sup>2</sup>, 7.1% ± 9.9%, <i>p</i> <i>&lt; </i>0.001) and perimeter (14 ± 1.7 cm to 13.5 ± 1.8 cm, 3.2% ± 5.9%, <i>p &lt; </i>0.001) were observed in 77.4% of our cohort immediately after TEER. Anterior–posterior (AP) diameter showed greater reduction (4.1 ± 0.6 cm to 3.8 ± 0.6 cm, <i>p &lt; </i>0.001, 6.3% ± 7.8%) compared to medial–lateral diameter (4.3 ± 0.5 cm to 4.2 ± 0.6 cm, <i>p &lt; </i>0.001, 3.2% ± 8%), and these changes resulted in a more elliptic valve at the end of the procedure (ellipticity from 105% ± 8% to 109% ± 10%, <i>p = </i>0.001). The reduction of the annulus dimensions correlated with the residual MR at discharge (<i>p</i> = 0.001), while these patients also achieved optimal long-term echocardiographic results with mild MR (<i>p = </i>0.019).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>TEER with PASCAL acutely reduces mitral annular dimensions, favoring a more elliptic valve shape, particularly through AP diameter reduction. These changes correlate with sustained MR improvement.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 9","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Cardiovascular Events Between Mitral Annular Disjunction and Left Atrial Reservoir Strain in Barlow's Disease 巴洛氏病患者二尖瓣环分离与左心房贮血池应变之间心血管事件的关系
IF 1.4 4区 医学
Yuta Torii, Tomoko Tani, Taiji Okada, Madoka Sano, Masaya Nagano, Aoi Hamano, Naoko Suganuma, Shoji Miyagawa, Junichi Kawai, Yutaka Furukawa
{"title":"Association of Cardiovascular Events Between Mitral Annular Disjunction and Left Atrial Reservoir Strain in Barlow's Disease","authors":"Yuta Torii,&nbsp;Tomoko Tani,&nbsp;Taiji Okada,&nbsp;Madoka Sano,&nbsp;Masaya Nagano,&nbsp;Aoi Hamano,&nbsp;Naoko Suganuma,&nbsp;Shoji Miyagawa,&nbsp;Junichi Kawai,&nbsp;Yutaka Furukawa","doi":"10.1111/echo.70274","DOIUrl":"https://doi.org/10.1111/echo.70274","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Mitral annular disjunction (MAD) has been suggested to be associated with malignant ventricular arrhythmias and sudden cardiac death. Otherwise, left atrial reservoir strain (LARS) has been reported to be useful in predicting risks of cardiovascular events in heart valve diseases. The current study aimed to investigate the relationship between cardiac events and echocardiographic characteristics in patients with Barlow's disease (BD).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods and Results</h3>\u0000 \u0000 <p>Sixty-nine consecutive patients with BD were enrolled between July 2011 and July 2018. Conventional echocardiographic indices, MAD, severity of mitral regurgitation, parameters of the mitral valve complex, and speckle-tracking echocardiography were evaluated. The primary endpoint was cardiac events as a composite of cardiac death and non-sustained ventricular tachycardia (NSVT). MAD was observed in 30 patients out of the 69 patients (43%). During a median follow-up of 7.3 years, cardiac death and NSVT occurred in nine patients (13%). Although no significant associations were observed among the severity of mitral regurgitation, left atrial volume index, and the morphology of the mitral valve complex, a significant association with cardiac events was identified in relation to the presence of MAD and low LARS (log-rank test, <i>p</i> &lt; 0.01, respectively)</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The presence of MAD and reduced LARS is significantly associated with an increased risk of cardiac events in patients with BD. These findings highlight the potential importance of MAD and LARS as novel markers for risk stratification in this population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 9","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70274","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144914998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Left Atrium Strain in Mitral Stenosis – A Narrative Review 左心房应变在二尖瓣狭窄中的作用综述
IF 1.4 4区 医学
Azin Alizadehasl, Fatemeh Dehghani
{"title":"Role of Left Atrium Strain in Mitral Stenosis – A Narrative Review","authors":"Azin Alizadehasl,&nbsp;Fatemeh Dehghani","doi":"10.1111/echo.70272","DOIUrl":"https://doi.org/10.1111/echo.70272","url":null,"abstract":"<div>\u0000 \u0000 <p>Mitral stenosis (MS) is a significant valvular heart disease that often leads to left atrial (LA) enlargement and dysfunction. The Latest developments in echocardiographic techniques, especially speckle-tracking echocardiography, have enabled the assessment of LA strain, providing insights into LA mechanics and its role in the pathophysiology of MS. This review discusses the implications of LA strain in patients with severe MS, its prognostic value, and potential therapeutic implications. A comprehensive narrative review was executed to report current findings in cardiovascular research. By searching in the electronic databases of Scopus, PubMed, Google Scholar, and Web of Science using keywords such as “Speckle Tracking”, “left atrium”, “Left atrium strain”, and “mitral stenosis”, relevant literature was found. Inclusion criteria encompassed peer-reviewed articles published in English at any time till March 2025. The results indicate that Left atrial strain analysis offers a promising tool for the evaluation of LA mechanics in individuals with severe MS. Its prognostic value highlights the importance of evaluating LA function beyond traditional echocardiographic parameters. Future research is warranted to validate these findings and study the potential for integrating LA strain into clinical practice for improved patient outcomes.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 9","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144910315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Real-World Feasibility and Challenges in Using LAS for Stress Echocardiography LAS用于应激超声心动图的现实可行性和挑战
IF 1.4 4区 医学
Muhammad Mudasir Atif
{"title":"Real-World Feasibility and Challenges in Using LAS for Stress Echocardiography","authors":"Muhammad Mudasir Atif","doi":"10.1111/echo.70277","DOIUrl":"https://doi.org/10.1111/echo.70277","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 8","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144897371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Importance of Developing New Tools to Assess Cardiac Amyloidosis Using Echocardiography 发展超声心动图评估心脏淀粉样变性新工具的重要性
IF 1.4 4区 医学
Claudio Tinoco Mesquita, Andréa Rodrigues da Costa, Roberto Magalhães Saraiva
{"title":"Importance of Developing New Tools to Assess Cardiac Amyloidosis Using Echocardiography","authors":"Claudio Tinoco Mesquita,&nbsp;Andréa Rodrigues da Costa,&nbsp;Roberto Magalhães Saraiva","doi":"10.1111/echo.70271","DOIUrl":"https://doi.org/10.1111/echo.70271","url":null,"abstract":"&lt;p&gt;Cardiac amyloidosis (CA) is one of the infiltrative cardiomyopathies and is caused by an abnormal accumulation of insoluble aggregates of misfolded proteins within the myocardium. Although considered a rare disorder, its prevalence has increased over the last decades due to increased detection, as a consequence of enhancement in imaging technologies, and population aging [&lt;span&gt;1, 2&lt;/span&gt;]. Specifically, in the US population, there was an increase in the prevalence rate (8 to 17 per 100 000 person-years) and incidence rate (18 to 55 per 100 000 person-years) from 2000 to 2012 [&lt;span&gt;3&lt;/span&gt;]. As CA is frequently undetected and portends a poor prognosis with a high mortality rate, early detection is of paramount importance in order to introduce therapies that can improve survival and quality of life [&lt;span&gt;4&lt;/span&gt;]. Unfortunately, CA is still overlooked among patients with heart failure with preserved ejection fraction.&lt;/p&gt;&lt;p&gt;Echocardiography carries a Class 1B recommendation for diagnosing CA and is the typical first cardiac imaging modality for these patients [&lt;span&gt;5&lt;/span&gt;]. In order to increase CA suspicion and diagnosis, several red flags on echocardiography were described by the The American Society of Echocardiography: increased left ventricular (LV) and right ventricular (RV) wall thickening, biatrial enlargement, increased LV wall thickness with low-voltage criteria on associated electrocardiogram, diastolic dysfunction (≥grade II) with elevated LV filling pressures, severely reduced mitral annular tissue Doppler velocities, reduced global longitudinal strain (GLS) with apical sparing, low-flow low-gradient aortic stenosis, pericardial effusion, increased atrial septal thickness, diffuse valve thickening, and preserved ejection fraction with low stroke volume index [&lt;span&gt;6&lt;/span&gt;]. However, the overlapping symptoms with other cardiac pathologies common in elderly population often result in diagnostic delays [&lt;span&gt;2&lt;/span&gt;]. Therefore, new tools to facilitate CA suspicion during echocardiography are of great importance. The paper by Lin et al. [&lt;span&gt;7&lt;/span&gt;] included 72 patients with primary light chain amyloidosis (pAL), with CA diagnosis confirmed by non-cardiac tissue biopsy in 51 of them, and described a nomogram model with a very good diagnostic performance. After evaluating the univariate association with CA diagnosis of several echocardiographic parameters, the authors proposed a model which included relative wall thickness (RWT), the ratio of mitral peak flow velocity in early diastole (E) to the pulsed tissue Doppler early diastolic peak velocity (e’) at the interventricular septal mitral annulus (E /e’ sep), ejection fraction to peak GLS ratio (EFSR) and RV fractional area change. The study of the combined predictive value of several echocardiographic parameters in CA is novel and very important, as the predictive value for CA diagnosis of the proposed nomogram was superior to the one observed by single echocardiograp","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 8","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/echo.70271","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144894442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Invasive Type AB Thymoma Presenting as Right Atrial Mass Causing Systemic Venous Obstruction 侵袭性AB型胸腺瘤表现为右心房肿块引起全身静脉阻塞
IF 1.4 4区 医学
Arnab Paul, Chaitanya Chittimuri, Sudipta Mondal, Swasthi S. Kumar, Nadeem Afroz Muslim
{"title":"An Invasive Type AB Thymoma Presenting as Right Atrial Mass Causing Systemic Venous Obstruction","authors":"Arnab Paul,&nbsp;Chaitanya Chittimuri,&nbsp;Sudipta Mondal,&nbsp;Swasthi S. Kumar,&nbsp;Nadeem Afroz Muslim","doi":"10.1111/echo.70273","DOIUrl":"https://doi.org/10.1111/echo.70273","url":null,"abstract":"<p>This presentation underscores the extensive differential diagnoses for right atrial masses, their myriad clinical manifestations, and highlights the invasive nature of even ostensibly “benign” thymomas.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 8","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144891698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ruptured Caseous Calcification of the Mitral Annulus With Left Ventricular–Left Atrial Fistula Formation Causing Hemolytic Anemia 二尖瓣环干酪样钙化破裂伴左心室-左房瘘形成引起溶血性贫血
IF 1.4 4区 医学
Ayano Kurihara, Kenji Harada, Sumika Wachi, Masafumi Sato, Kazuomi Kario
{"title":"Ruptured Caseous Calcification of the Mitral Annulus With Left Ventricular–Left Atrial Fistula Formation Causing Hemolytic Anemia","authors":"Ayano Kurihara,&nbsp;Kenji Harada,&nbsp;Sumika Wachi,&nbsp;Masafumi Sato,&nbsp;Kazuomi Kario","doi":"10.1111/echo.70265","DOIUrl":"https://doi.org/10.1111/echo.70265","url":null,"abstract":"<p>This case highlights a rare yet clinically significant complication of caseous calcification of the mitral annulus (CCMA), wherein three-dimensional transesophageal echocardiography clearly delineated a left ventricular-to-left atrial fistula secondary to CCMA rupture, resulting in hemolytic anemia.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 8","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144888435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Aortic Arch Wall Motion Velocities in Severe Aortic Stenosis: A Transthoracic and Transesophageal Echocardiography Study 重度主动脉狭窄的主动脉弓壁运动速度评估:经胸和经食管超声心动图研究
IF 1.4 4区 医学
Abdullah Yildirim, Omer Genc, Emre Sezici, Fadime Koca, Guluzar Tras, Ahmet Suha Arslan, Emre Pacaci, Mustafa Lutfullah Ardic, Gokhan Alici, Mukremin Coskun, Yeliz Guler, Akkan Avci, Mert Evlice, Ibrahim Halil Kurt, Gulhan Yuksel
{"title":"Assessment of Aortic Arch Wall Motion Velocities in Severe Aortic Stenosis: A Transthoracic and Transesophageal Echocardiography Study","authors":"Abdullah Yildirim,&nbsp;Omer Genc,&nbsp;Emre Sezici,&nbsp;Fadime Koca,&nbsp;Guluzar Tras,&nbsp;Ahmet Suha Arslan,&nbsp;Emre Pacaci,&nbsp;Mustafa Lutfullah Ardic,&nbsp;Gokhan Alici,&nbsp;Mukremin Coskun,&nbsp;Yeliz Guler,&nbsp;Akkan Avci,&nbsp;Mert Evlice,&nbsp;Ibrahim Halil Kurt,&nbsp;Gulhan Yuksel","doi":"10.1111/echo.70266","DOIUrl":"https://doi.org/10.1111/echo.70266","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>This study aimed to evaluate the diagnostic utility of a novel parameter—arcus aorta wall motion velocities (AA-WMV)—measured by pulse-wave tissue Doppler imaging (PW-TDI) during TEE, and to compare its performance with established stiffness indices.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this prospective study, 196 patients with aortic stenosis (AS) and 128 controls without AS underwent TEE. AA-WMV parameters—systolic (Vs) and diastolic (Vd) velocities—were assessed using PW-TDI of the aortic arch. Conventional aortic stiffness markers, including valvuloarterial impedance (ZVA), total arterial compliance index (TAC<i>-index</i>), pulse wave velocity, and aortic intima-media thickness (Ao-IMT), were also measured.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Vs (3.35 ± 0.73 vs. 4.08 ± 0.69 cm/s, <i>p &lt; </i>0.001) and Vd (2.65 ± 0.98 vs. 3.67 ± 0.65 cm/s, <i>p &lt;</i> 0.001) were significantly lower in AS patients compared to controls. In multivariable logistic regression, Vs (aOR:0.27, 95% CI: 0.14–0.55, <i>p &lt; </i>0.001) and Vd (aOR:0.14, 95% CI: 0.07–0.31, <i>p &lt; </i>0.001) remained independent predictors of AS, alongside stroke volume-index and interventricular septal thickness. ROC analysis demonstrated the highest discriminative capacity for Vd (AUC <i>= </i>0.837), followed by Vs (AUC <i>= </i>0.783). The combined Vs+Vd model yielded optimal performance (C<i>-index = </i>0.87), improved calibration (Brier score <i>= </i>0.145), and superior model fit (pseudo-R<sup>2</sup> <i>= </i>0.337, AIC <i>= </i>274.3). Compared to the Vs model alone, the combined model significantly improved reclassification metrics, including net reclassification improvement (NRI <i>= </i>105.6%, <i>p &lt; </i>0.001), integrated discrimination improvement (IDI <i>= </i>18.7%, <i>p &lt; </i>0.001), and median improvement index (4.9%, <i>p &lt; </i>0.001). The Vs+Vd model also provided greater net clinical benefit.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>AA-WMV parameters—particularly Vd—offer a simple, reproducible, and effective approach for evaluating aortic stiffness in AS. While Vs and Vd individually hold diagnostic value, their combined use enhances discriminatory and prognostic accuracy, surpassing traditional aortic stiffness indices in patients undergoing TEE.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 8","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144869178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Unique Double-Chambered Left Ventricle 独特的双腔左心室
IF 1.4 4区 医学
Wen-Xia Zhou, Bing-Jie Li, Ye-Ting Bian, Xin Wei
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