Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques最新文献

{"title":"Effects of Isoproterenol Administration in Dobutamine Stress Echocardiography","authors":"Puja A. Patel,&nbsp;Zachary N. Parsia,&nbsp;Tsion Aberra,&nbsp;Nayrana Tillman,&nbsp;Martin Mathias,&nbsp;Adam Newell Bohn Johnson,&nbsp;Akanksha Girish,&nbsp;Brototo Deb,&nbsp;Carolina Valdiviezo,&nbsp;Christy Kaiser,&nbsp;Monvadi B. Srichai","doi":"10.1111/echo.70081","DOIUrl":"10.1111/echo.70081","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study evaluated the safety and efficacy of isoproterenol administration as an adjunct for achievement of target heart rate (HR) during dobutamine stress echocardiography (DSE).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>In DSE, optimal accuracy is achieved when a target HR of 85% of maximal predicted heart rate (MPHR) is attained. Although rarely studied, intravenous isoproterenol has been used as an adjunct therapy to dobutamine and atropine to increase chronotropic response during pharmacologic stress testing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We identified 5569 DSE studies during which 264 received isoproterenol at MedStar Georgetown University Hospital from August 2011 to March 2023. Of the studies receiving isoproterenol, we collected clinical and echocardiographic parameters from each study to assess the effects of isoproterenol administration, including downstream events.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In 264 examinations with isoproterenol, 169 (64%) achieved 85% MPHR. Among these, 103 (39%) developed premature ventricular contractions, 79 (30%) developed symptoms including nausea/vomiting in 44 (17%), and chest pain in 15 (6%). There was a hypertensive response to stress in 53 studies (20%) and a hypotensive response in 37 studies (14%). There was no significant increase in 30-day and 1-year death when compared to studies that did not receive isoproterenol.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Isoproterenol can effectively be used as an adjunctive agent in DSE to achieve the requisite hemodynamic stress for evaluation of ischemia, with a similar rate of side effects and complications compared to dobutamine and atropine stress testing.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chiari Network With Associated Cyanosis in a 3-Year-Old Girl","authors":"Jingya Li,&nbsp;Ruijuan Su,&nbsp;Yan Sun,&nbsp;Guowen Liu,&nbsp;Liyuan Xu,&nbsp;Jiao Yang,&nbsp;Ning Ma","doi":"10.1111/echo.70090","DOIUrl":"10.1111/echo.70090","url":null,"abstract":"<p>We reported a 3-year-old girl with cyanosis. The patient was diagnosed with an obstructive Chiari network, which is an unrecognized cause of cyanosis. Echocardiography was used to diagnose this disease and provide additional information on flow and pressure gradients.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 2","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes Mellitus as a Disease Modifier in Hypertrophic Cardiomyopathy","authors":"Nelya Oryshchyn","doi":"10.1111/echo.70075","DOIUrl":"10.1111/echo.70075","url":null,"abstract":"","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical, Analytical, and Echocardiographic Associations of Impaired Cardiorespiratory Fitness After Anthracycline Chemotherapy in Breast Cancer: EPIC Fitness Study","authors":"Mariana Tinoco,&nbsp;Margarida Castro,&nbsp;Luísa Pinheiro,&nbsp;Tamara Pereira,&nbsp;Mário Lourenço,&nbsp;Filipa Castro,&nbsp;Liliana Oliveira,&nbsp;Alexandra Teixeira,&nbsp;Gonçalo Torres,&nbsp;Paula Mota,&nbsp;Mafalda Cunha,&nbsp;Marco Francisco Silva,&nbsp;Vítor Sousa,&nbsp;Mariana Saavedra,&nbsp;Geraldo Dias,&nbsp;Bebiana Faria,&nbsp;Filipa Cordeiro,&nbsp;Marina Fernandes,&nbsp;Emidio Mata,&nbsp;Joana Gomes,&nbsp;Joana Rebelo,&nbsp;Daniela Ferreira,&nbsp;Rita Andrade,&nbsp;Rita Vaz,&nbsp;Isabel Oliveira,&nbsp;Sónia Barros,&nbsp;Silva Sanz,&nbsp;Inocência Machado,&nbsp;Filipa Almeida,&nbsp;Olga Azevedo,&nbsp;António Lourenço","doi":"10.1111/echo.70083","DOIUrl":"10.1111/echo.70083","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>This study explores the effects of anthracycline chemotherapy (AC) on breast cancer patients, focusing on changes in body composition, advanced echocardiographic parameters at rest and during exercise, and biomarkers; and subsequently assesses whether these parameters are associated with impaired cardiorespiratory fitness (CRF).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this prospective study, we evaluated women with early-stage breast cancer undergoing AC at three visits: before AC, 1 month after, and 6 months post-AC.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The study included 32 women with breast cancer, with functional disability increasing from 9.0% pre-AC to 43.8% at 1 month and 53.1% at 6 months post-AC. At 1 month, patients with functional disability exhibited higher rates of cancer therapy-related cardiac dysfunction (CTRCD) (85.7% vs. 55.5%) and, during exercise, showed lower left ventricular ejection fraction (LVEF), reduced contractile reserve and stroke volume (SV); along with elevated IL-6, PlGF, and MPO levels. By 6 months, these patients maintained higher CTRCD rates (35.3% vs. 0%), lower SV and cardiac output (CO), reduced global longitudinal strain (GLS), and decreased global work index (GWI). During exercise, they had lower SV; additionally, they exhibited higher MPO levels and increased body and visceral fat. In our multivariable model: age, body fat, resting GWI, exercise LVEF, and CO were independently associated with VO₂peak.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Significant and persistent CRF reductions are common in breast cancer patients post-AC. While resting LVEF and GLS were not linked to VO₂peak, resting MWI and exercise LVEF and CO were, potentially identifying patients at increased long-term heart failure risk who would benefit from cardioprotective strategies like cardio-oncology rehabilitation. It is important to recognize that impaired CRF is multifactorial, as demonstrated by age and body fat being independently associated with VO₂peak, and the impact of non-cardiac factors should be better studied.</p>\u0000 \u0000 <p>Our findings highlight the need for further research on CTRCD definition, suggesting that CPET and advanced exercise echocardiography could enhance risk stratification.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging Lessons From Multidisciplinary Team Meetings at a Quaternary Referral Center: A Case-Based Review of Radiology Findings in Complex Adult Congenital Heart Disease","authors":"Anjuna Reghunath,&nbsp;Ahmed Kharabish,&nbsp;Monika Radike","doi":"10.1111/echo.70082","DOIUrl":"10.1111/echo.70082","url":null,"abstract":"<div>\u0000 \u0000 <p>Optimal management of adult congenital heart disease (ACHD) requires a multidisciplinary team (MDT) approach, fostering a collaborative culture over an individualistic approach. Within this framework, subspecialty-trained radiologists provide crucial imaging expertise, supporting cardiologists, surgeons, and interventional cardiologists in diagnoses, treatment planning, and follow-up evaluations. Advanced imaging tools and a nuanced understanding of surgical and interventional procedures enable radiologists to provide valuable insights to clinicians. In this review, we discuss the structure of ACHD MDT meeting at a quaternary center, briefly review the general principles of interventions in ACHD and the subsequent complications encountered in adulthood, formulate an approach to imaging and reporting such complex repaired cases, and review the key information to be mentioned in the report for further surgery/intervention. In this review, we use the format of eight key take-home lessons from an MDT management practice in ACHD.</p>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Relevance of Senior-Supervised Transthoracic Echocardiography in Clinical Practice and Research: An Editorial Commentary and Systematic Review","authors":"Daniel A. Morris","doi":"10.1111/echo.70085","DOIUrl":"10.1111/echo.70085","url":null,"abstract":"&lt;p&gt;In clinical practice, senior cardiologists in echocardiography laboratories frequently find clinically significant findings during supervised transthoracic echocardiography (TTE) that less experienced colleagues had not identified [&lt;span&gt;1&lt;/span&gt;]. These findings, which are exclusively uncovered during senior-supervised TTE, encompass a wide range of abnormalities, from apical left ventricular (LV) thrombus to subtle changes in LV wall thickness [&lt;span&gt;1&lt;/span&gt;]. However, the most commonly affected parameters or evaluations are the LV ejection fraction (LVEF) and the severity of valvular heart disease [&lt;span&gt;1-3&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Several studies have highlighted the clinical importance of senior-supervised TTE in determining the final value of LVEF that should be reported [&lt;span&gt;2&lt;/span&gt;]. In effect, as demonstrated in the present systematic review (see Table 1), the absolute mean difference in LVEF between evaluations conducted by senior cardiologists and those by non-senior practitioners is approximately 3% absolute LVEF units, with a range of 0%–8% (95% confidence interval: 1.8%–4.4%) (see Table 1). These discrepancies have significant clinical implications. For instance, a senior-supervised evaluation might classify a patient's LVEF as &lt; 35% rather than &gt; 40% (see Table 1). This change in LVEF value would indicate the initiation of specific heart failure therapies or consideration of advanced interventions such as cardiac resynchronization therapy or implantable cardioverter–defibrillators, decisions that might not have been made without senior supervision.&lt;/p&gt;&lt;p&gt;The evaluation of valvular heart disease severity is another critical area where senior-supervised TTE plays a pivotal role [&lt;span&gt;3&lt;/span&gt;]. It is not uncommon for senior-supervised TTE to identify severe aortic stenosis (AS), severe mitral regurgitation, or severe tricuspid regurgitation, whereas less experienced colleagues reported only moderate severity [&lt;span&gt;1, 3&lt;/span&gt;]. In cases of AS, discrepancies often arise from differences in the measurement of the LV outflow tract (LVOT) diameter and the peak aortic valve velocity obtained via continuous-wave Doppler [&lt;span&gt;3, 18&lt;/span&gt;]. In this issue of the journal, Velders et al. demonstrated significant and clinically relevant differences in LVOT diameter measurements between evaluations conducted by senior cardiologists in an academic echocardiography core laboratory and routine or screening measurements from study centers [&lt;span&gt;19&lt;/span&gt;]. Similar findings have been corroborated by other studies comparing LVOT diameter and peak aortic valve velocity measurements in patients with AS and bioprosthetic aortic valves between academic echocardiography core laboratories or senior cardiologists and study centers [&lt;span&gt;20, 21&lt;/span&gt;].&lt;/p&gt;&lt;p&gt;Based on the above-mentioned evidence, the evidence shown in the current systematic review and current expert consensus recommendations [&lt;span&gt;1-26&lt;/span&gt;], senior supervision of TTE is clinica","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758482/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143034639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Two- and Three-dimensional Transthoracic Echocardiographic Identification of Esophageal Stent","authors":"John LaForge,&nbsp;Donovon Allen,&nbsp;Regina Dickey,&nbsp;Navin Nanda","doi":"10.1111/echo.70080","DOIUrl":"10.1111/echo.70080","url":null,"abstract":"<p>First echocardiographic detection of esophageal stent.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11745407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Value of Transvalvular Flow Rate in Aortic Stenosis: Implications for Risk Stratification","authors":"Elad M. Bar Gil,&nbsp;Ruslan Sergienko,&nbsp;Nir Roguin,&nbsp;Shoham Birman,&nbsp;Sergio L. Kobal","doi":"10.1111/echo.70077","DOIUrl":"10.1111/echo.70077","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Timing of treatment of aortic stenosis (AS) is of key importance. AS severity is currently determined by transthoracic echocardiography (TTE) with a main focus on mean trans-aortic gradients. However, echocardiography has its limitations. The transvalvular flow rate (<i>Q</i>), is defined as the ratio of stroke volume (SV) to ejection time (ET): <i>Q</i> = SV/ET.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>To examine the prognostic value of aortic transvalvular flow rate (<i>Q</i>), in patients with moderate or severe AS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Clinical data from 824 patients diagnosed with AS between 2017 and 2020, and followed up until 2022 for four clinical outcomes: mortality, congestive heart failure (CHF), transcatheter aortic valve implantation (TAVI), and surgical aortic valve replacement (SAVR) was used for this retrospective study. Univariate and multivariate regression analyses were performed for the whole cohort and for the moderate AS subgroup, to identify prognostic markers. Kaplan-Meier survival analysis was conducted for different transvalvular flow rates and AS severities.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Findings demonstrate that lower <i>Q</i> is a significant risk factor for all-cause mortality even when adjusted for other echocardiographic and clinical variables. Survival analysis for the composite outcome occurrence (TAVI, SAVR, CHF, or mortality) and mortality showed significant differences between groups stratified by AS severity and <i>Q</i> (<i>p</i> value &lt;0.0001). Specifically, <i>Q</i> was more substantial in the moderate AS group.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Transvalvular flow rate (<i>Q</i>) is independently prognostic for all-cause mortality. Furthermore, patients with moderate AS and lower <i>Q</i> should be closely monitored. Flow rate assessment should be integrated into the diagnosis, classification, and prognosis framework for AS.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left Atrial Mechanics and Atrioventricular Coupling in Hypertension With Supra-Normal Left Ventricular Ejection Fraction","authors":"Chong Liu,&nbsp;Wen-Jun Xu,&nbsp;Jia-Wei Tian","doi":"10.1111/echo.70079","DOIUrl":"10.1111/echo.70079","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Supra-normal left ventricular ejection fraction (snLVEF) represents a heterogeneous group with distinct prognoses. Left atrial (LA) strain, measured by speckle tracking echocardiography (STE), is a validated prognostic indicator. This study aimed to evaluate LA and left ventricular (LV) mechanical strains in hypertensive patients with snLVEF.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective study included 101 patients (mean age 59.7 ± 8.4 years; 61.4% men) with primary arterial hypertension and preserved LVEF (≥50%). Patients were categorized into low-normal LVEF (lnLVEF; 50%–59%), mid-normal LVEF (mnLVEF; 60%–69%), and snLVEF (≥70%). LV global longitudinal strain (LVGLS) and LA strains during reservoir (LASr), conduit (LAScd), and contraction (LASct) phases were measured using STE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Relative wall thickness was significantly higher in snLVEF patients compared to mnLVEF (<i>p</i> &lt; 0.01), with no difference in LVGLS (<i>p</i> = 0.933). Compared to mnLVEF, snLVEF patients had reduced LASr and LAScd (both <i>p</i> &lt; 0.01) but preserved LASct (<i>p</i> = 0.057). In contrast, lnLVEF patients showed greater reductions in all phasic LA strains (all <i>p</i> &lt; 0.01). Loess regression revealed an inverted U-shaped relationship between LASr and LVEF, peaking at LVEF 65%–70%. The mitral E/e′_mean ratio and LVGLS correlated moderately to strongly with LASr (<i>r</i> = −0.39 and <i>r</i> = −0.65, respectively; both <i>p</i> &lt; 0.001).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Hypertensive patients with snLVEF exhibit impaired LA reservoir and conduit functions while maintaining pump function, suggesting snLVEF may be an intermediate stage between mnLVEF and lnLVEF as hypertension progresses. Further studies are needed to explore the prognostic potential of LA strain in this population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Application of the Fetal HQ Technique in the Evaluation of Normal Fetal Cardiac Function at Different Gestational Weeks","authors":"Xiao-rong Su,&nbsp;Ai-lin Wang,&nbsp;Hong-xia Tie,&nbsp;Wen-rui Wu,&nbsp;Wen-dong Zhang,&nbsp;Ke-xiong Niu,&nbsp;Tian-gang Li","doi":"10.1111/echo.70078","DOIUrl":"10.1111/echo.70078","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To investigate the clinical value of fetal heart quantification (fetal HQ) in the evaluation of normal fetal heart size, morphology, and cardiac function at different gestational weeks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A total of 101 pregnant women diagnosed with a healthy fetus by fetal echocardiography from September 2021 to December 2023 were selected and classified into four different periods of gestational weeks: 20–28 weeks (25 cases), 29–32 weeks (26 cases), 33–36 weeks (26 cases), and 37–40 weeks (24 cases). Quantitative analyses were performed by automatically tracking the endocardium using fetal HQ software that comes with the Voluson E10 from GE. To investigate the correlation between four-chambered vesicle length end-diastolic (4CV LED), four-chambered vesicle transverse width end-diastolic (4CV TWED), global sphericity index (GSI), ejection fraction (EF), stroke volume (SV), cardiac output (CO), and gestation age (GA), and the variability of normal fetal cardiac morphology and cardiac function at different gestational weeks.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A statistically significant difference was observed between 4CV LED and 4CV TWED in normal fetuses at different gestational weeks (<i>p</i> &lt; 0.05), which exhibited a positive correlation with gestational week. Conversely, no significant correlation was identified between GSI and gestational week (<i>p</i> &gt; 0.05). The mean GSI of 101 normal fetuses was found to be 1.25 ± 0.09. A comparative analysis of EF, SV, and CO in normal fetuses at different gestational weeks revealed statistically significant differences in SV and CO (<i>p</i> &lt; 0.05), which gradually increased with gestational weeks, whereas there was no statistically significant difference in EF (<i>p</i> &gt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Fetal HQ represents a straightforward and dependable method for evaluating GSI and 24-segment SI of the left and right ventricles, which can provide a certain theoretical basis for the clinical quantitative evaluation of fetal cardiac geometry and cardiac function.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50558,"journal":{"name":"Echocardiography-A Journal of Cardiovascular Ultrasound and Allied Techniques","volume":"42 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143015718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}