Journal of AaposPub Date : 2024-08-01DOI: 10.1016/j.jaapos.2024.103938
{"title":"Congenital epiblepharon in Chinese school-age children: a cross-sectional study","authors":"","doi":"10.1016/j.jaapos.2024.103938","DOIUrl":"10.1016/j.jaapos.2024.103938","url":null,"abstract":"<div><h3>Purpose</h3><p>To investigate the prevalence and body mass index<span> (BMI) associations of congenital lower epiblepharon in children in China and the difference in the refractive errors between children with and without epiblepharon.</span></p></div><div><h3>Methods</h3><p>Children 6-12 years of age in Beichen District of Tianjin were screened for congenital epiblepharon from September to October 2017. All children underwent slit-lamp examination, strabismus screening, visual acuity examination and refraction. Weight and height were also recorded. The prevalence of lower epiblepharon in school-age children was evaluated, and its association with age, sex, BMI, and refractive error was analyzed.</p></div><div><h3>Results</h3><p>A total of 28,225 children were examined; 564 had epiblepharon. The prevalence of epiblepharon was found to be, for 6-year-olds, 2.50%; for 7-year-olds, 2.13%; for 8-year-olds, 2.10%; for 9-year-olds, 1.97%; for 10-year-olds, 1.85%; for 11-year-olds, 1.67%; and for 12-year-olds, 1.19% (<em>P</em><span> < 0.05). The prevalence of overweight and obesity in children with epiblepharon was found to be 16.7% and 47.2%, respectively. The prevalence and degree of astigmatism<span> was higher than in nonepiblepharon children. We found a possible association between severity of astigmatism and severity of epiblepharon.</span></span></p></div><div><h3>Conclusions</h3><p>In our study, the prevalence of epiblepharon decreased with advancing age, and the majority of children with epiblepharon were found to be overweight or obese. Epiblepharon was associated with astigmatism.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141136888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2024-08-01DOI: 10.1016/j.jaapos.2024.103939
{"title":"Prolonged hypotony maculopathy following uneventful strabismus surgery","authors":"","doi":"10.1016/j.jaapos.2024.103939","DOIUrl":"10.1016/j.jaapos.2024.103939","url":null,"abstract":"<div><p>Hypotony is a rare postoperative complication of strabismus<span><span> surgery. Resolution has been reported to occur within 1 month of surgery. Here, we describe the case of a 14-year-old boy with prolonged hypotony maculopathy following uneventful bilateral medial rectus recession. The hypotony resolved without long-term </span>sequela<span><span><span> after 7 months of treatment with topical steroids and atropine. </span>Ultrasound biomicroscopy<span> revealed a ciliary body effusion, which we hypothesize was the cause of decreased </span></span>aqueous humor production and hypotony.</span></span></p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141181325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2024-08-01DOI: 10.1016/j.jaapos.2024.103948
{"title":"Bilateral nonarteritic ischemic optic neuropathy and retinal ischemia in a pediatric dialysis patient","authors":"","doi":"10.1016/j.jaapos.2024.103948","DOIUrl":"10.1016/j.jaapos.2024.103948","url":null,"abstract":"<div><p>A nearly 3-year-old boy on nightly dialysis presented emergently with sudden loss of vision. On examination, his visual acuity was light perception in the right eye and no light perception in the left eye. There was bilateral optic disk edema, diffuse pallor of posterior poles, and a cherry red spot in the left fundus. The patient was subsequently found to be hemodynamically unstable and admitted to the pediatric intensive care unit with presumed septic shock. Optical coherence tomography revealed paracentral acute middle maculopathy lesions in the right eye and diffusely thick retina in the left eye. Magnetic resonance imaging and magnetic resonance angiography of the brain and vessels did not reveal any acute findings. The patient’s presentation was most consistent with bilateral nonarteritic ischemic optic neuropathy and unilateral central retinal artery occlusion. On repeat evaluation 9 months later, vision was largely unchanged.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1091853124002283/pdfft?md5=5eca7eb591fdf3b17b71807f355679c6&pid=1-s2.0-S1091853124002283-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141200841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2024-08-01DOI: 10.1016/j.jaapos.2024.103937
{"title":"Leukemic infiltration of the ciliary body in a child with T-cell acute lymphoblastic leukemia","authors":"","doi":"10.1016/j.jaapos.2024.103937","DOIUrl":"10.1016/j.jaapos.2024.103937","url":null,"abstract":"<div><p>A 14-year-old boy presented after 2 months of vision loss<span><span><span><span>, redness, and pain in the right eye, initially treated as anterior uveitis with </span>topical corticosteroids<span><span>. He had a 1-year history of T-cell acute lymphoblastic leukemia, which had been in remission for 6 months. On examination, visual acuity in the right eye was light perception, with 4+ </span>anterior chamber cells, pupillary membrane, and an intumescent cataract. </span></span>Ultrasound biomicroscopy<span> (UBM) revealed a ciliary body mass and capsular bag rupture. After consultation with his oncologist, he received 10 radiotherapy sessions. At 1 month, UBM showed resolution of the mass. After 1 year of remission, the patient underwent </span></span>pars plana vitrectomy<span>, pupillary membranectomy, and placement of a scleral-fixated intraocular lens. Thirty months after surgery, visual acuity was 20/25. Leukemic infiltration of the ciliary body is a rare manifestation of the disease that is often misdiagnosed as uveitis.</span></span></p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2024-08-01DOI: 10.1016/j.jaapos.2024.103952
{"title":"Small tuck for superior oblique palsy","authors":"","doi":"10.1016/j.jaapos.2024.103952","DOIUrl":"10.1016/j.jaapos.2024.103952","url":null,"abstract":"<div><h3>Purpose</h3><p>To investigate the surgical outcomes of small superior oblique (SO) tuck—denoting minimal tendon laxity—in patients with unilateral SO palsy.</p></div><div><h3>Methods</h3><p><span>The medical records of consecutive patients treated with ≤6 mm SO tuck from 2000 to 2018 at Kellogg Eye Center, University of Michigan, were reviewed retrospectively. Tendon tucks were performed to a fairly uniform tension in an amount that just eliminated slack in the tendon. Pre- and postoperative motility measurements were compared. Patients were excluded if they had a history of prior </span>strabismus surgery or concurrent vertical rectus or inferior oblique surgery.</p></div><div><h3>Results</h3><p><span>A total of 27 cases (14 males) met inclusion criteria. The median age at surgery was 47 years (range 3–74 years). The mean SO tuck (total, both arms of tuck) was 4.9 mm (range, 2–6 mm). After surgery, median hypertropia decreased from 9</span><sup>Δ</sup> to 1<sup>Δ</sup> in primary position and from 20<sup>Δ</sup> to 4<sup>Δ</sup><span> in the SO field of action (contralateral downgaze). Lateral incomitance (difference in hypertropia between contralateral and ipsilateral gaze) decreased from 10</span><sup>Δ</sup> to 2<sup>Δ</sup> (<em>P</em><span><span> < 0.001 in each case). Six patients had diplopia in upgaze postoperatively that was not symptomatic enough to require </span>reoperation. Six patients had residual hypertropia requiring additional surgery.</span></p></div><div><h3>Conclusions</h3><p>Small SO tuck provided disproportionate correction of hypertropia in the SO field of action and nearly eliminated lateral incomitance without producing unacceptable iatrogenic Brown syndrome. Even in the absence of tendon laxity, SO tuck was a good surgical option for SO palsy in our cohort where there was marked lateral incomitance and the greatest deviation was in the SO field of action.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141318820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2024-08-01DOI: 10.1016/j.jaapos.2024.103935
{"title":"Malignant rhabdoid tumor of the orbit in an infant","authors":"","doi":"10.1016/j.jaapos.2024.103935","DOIUrl":"10.1016/j.jaapos.2024.103935","url":null,"abstract":"<div><p><span><span>We present the case of an infant with rapidly progressing orbital tumor that had initial radiological and clinical features of both rhabdomyosarcoma and </span>capillary hemangioma. The patient was eventually diagnosed with </span>malignant rhabdoid tumor of the orbit. We discuss the salient histological and radiological features of our case and review the literature on orbital malignant rhabdoid tumors.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140960578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2024-06-01DOI: 10.1016/j.jaapos.2024.103932
Francisco Altamirano-Lamarque MD, Efren Gonzalez MD, Isdin Oke MD, MPH
{"title":"The association between race and age of diagnosis of retinoblastoma in United States children","authors":"Francisco Altamirano-Lamarque MD, Efren Gonzalez MD, Isdin Oke MD, MPH","doi":"10.1016/j.jaapos.2024.103932","DOIUrl":"10.1016/j.jaapos.2024.103932","url":null,"abstract":"","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140892868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2024-06-01DOI: 10.1016/j.jaapos.2024.103933
Yeabsira Mesfin BS , Alan Kong MD , Benjamin T. Backus PhD , Michael Deiner PhD , Yvonne Ou MD , Julius T. Oatts MD
{"title":"Pilot study comparing a new virtual reality–based visual field test to standard perimetry in children","authors":"Yeabsira Mesfin BS , Alan Kong MD , Benjamin T. Backus PhD , Michael Deiner PhD , Yvonne Ou MD , Julius T. Oatts MD","doi":"10.1016/j.jaapos.2024.103933","DOIUrl":"10.1016/j.jaapos.2024.103933","url":null,"abstract":"<div><h3>Purpose</h3><p>To assess the feasibility and performance of Vivid Vision Perimetry (VVP), a new virtual reality (VR)–based visual field platform.</p></div><div><h3>Methods</h3><p>Children 7-18 years of age with visual acuity of 20/80 or better undergoing Humphrey visual field (HVF) testing were recruited to perform VVP, a VR-based test that uses suprathreshold stimuli to test 54 field locations and calculates a fraction seen score. Pearson correlation coefficients were calculated to evaluate correlation between HVF mean sensitivity and VVP mean fraction seen scores. Participants were surveyed regarding their experience.</p></div><div><h3>Results</h3><p>A total of 37 eyes of 23 participants (average age, 12.9 ± 3.1 years; 48% female) were included. All participants successfully completed VVP testing. Diagnoses included glaucoma (12), glaucoma suspect (7), steroid-induced ocular hypertension (3), and craniopharyngioma (1). Sixteen participants had prior HVF experience, and none had prior VVP experience, although 7 had previously used VR. Of the 23 HVF tests performed, 9 (39%) were unreliable due to fixation losses, false positives, or false negatives. Similarly, 35% of VVP tests were unreliable (as defined by accuracy of blind spot detection). Excluding unreliable HVF tests, the correlation between HVF average mean sensitivity and VVP mean fraction seen score was 0.48 (<em>P</em> = 0.02; 95% CI, 0.09-0.74). When asked about preference for the VVP or HVF examination, all participants favored the VVP, and 70% were “very satisfied” with VVP.</p></div><div><h3>Conclusions</h3><p>In our cohort of 23 pediatric subjects, VVP proved to be a clinically feasible VR-based visual field testing, which was uniformly preferred over HVF.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1091853124002039/pdfft?md5=b3a481391874f35f579ee5a209a3984f&pid=1-s2.0-S1091853124002039-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140904306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2024-06-01DOI: 10.1016/j.jaapos.2024.103927
Maude Anderson MD, FRCSC, Erick D. Bothun MD
{"title":"Novel superior oblique anterior fiber plication with or without adjustable sliding knot for extorsion","authors":"Maude Anderson MD, FRCSC, Erick D. Bothun MD","doi":"10.1016/j.jaapos.2024.103927","DOIUrl":"10.1016/j.jaapos.2024.103927","url":null,"abstract":"<div><h3>Purpose</h3><p>To report a novel surgical technique to correct excyclotropia, consisting of a superior oblique anterior fibers plication (SOAFP) with or without a hemihangback anterior knot, allowing access for postoperative adjustment.</p></div><div><h3>Methods</h3><p>A retrospective interventional case series was conducted. Fourteen patients, 21-92 years of age, underwent SOAFP (18 eyes, 14 eyes on adjustable), at the Mayo Clinic in Rochester, Minnesota. SOAFP was the only procedure performed in 12 eyes; in 6 it was performed in conjunction with up to four horizontal rectus muscle recession, resection, and/or plication. Ocular alignment was assessed with prism and alternate cover and double Maddox rod tests; preoperatively, at initial and final (closest to 6-8 weeks) postoperative visits.</p></div><div><h3>Results</h3><p>Preoperative torsion ranged from 2° to 30° of extorsion (mean, 10.14 ± 7.01). A SOAFP of 2–30 mm (mean, 8.93 ± 5.63) was performed. At the initial postoperative examination, mean intorsional shift was 11.18 ± 7.37, accounting for 1.86° ± 1.04° of correction per millimeter of plication. Three eyes were adjusted after the initial visit to obtain a stronger plication effect targeting of 5° intorsion. At the final visit, 61 ± 23 days postoperatively, mean extorsion was 1.21° ± 2.29°, ranging from 5° of extorsion to 3 of intorsion. Mean final intorsional shift was 9.14 ± 7.53°, accounting for a 1.16 ± 0.50° of correction per millimeter of plication. Of our 14 patients, 13 had improvement in diplopia.</p></div><div><h3>Conclusions</h3><p>In our study cohort, SOAFP allowed for targeted and easily adjustable correction of extorsion.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140863051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2024-06-01DOI: 10.1016/j.jaapos.2024.103925
Christina H. Frater BS , Maura R.Z. Ruzhnikov MD, FACMG , Shannon Beres MD , Deborah Alcorn MD , Ann Shue MD , Rebecca J. Levy MD, PhD
{"title":"Ocular features of NGLY1 deficiency from a prospective longitudinal cohort","authors":"Christina H. Frater BS , Maura R.Z. Ruzhnikov MD, FACMG , Shannon Beres MD , Deborah Alcorn MD , Ann Shue MD , Rebecca J. Levy MD, PhD","doi":"10.1016/j.jaapos.2024.103925","DOIUrl":"10.1016/j.jaapos.2024.103925","url":null,"abstract":"<div><h3>Background</h3><p>NGLY1 deficiency is a rare autosomal recessive disorder with core features of global developmental delay, liver enzyme abnormalities, movement disorder, polyneuropathy, and hypo- or alacrima. We characterized the full spectrum and evolution of the ocular phenotype in a prospective natural history of NGLY1 deficiency.</p></div><div><h3>Methods</h3><p>We collected ophthalmological data on 29 individuals with NGLY1 deficiency in a natural history study. Medical records were reviewed to confirm caregiver-reported symptoms. Of the 29, 15 participants appeared for at least one ophthalmological examination.</p></div><div><h3>Results</h3><p>Caregivers reported at least one ocular sign or symptom in 90% of participants (26/29), most commonly decreased tears, refractive error, and chronic infection. Daily eye medication, including artificial tears, ophthalmic ointment, and topical antibiotics were used by 62%. Ophthalmological examination confirmed refractive errors in 93% (14/15) and corneal abnormalities in 73% (11/15).</p></div><div><h3>Conclusions</h3><p>Given nearly universal hypolacrima and additional prominent ocular findings in NGLY1 deficiency, a targeted ocular history and ophthalmologic examination may facilitate prompt diagnosis and early initiation of preventive eye care, preserving vision and overall ocular health.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}