与儿童青光眼手术相关的脉络膜上腔出血风险因素：病例对照研究。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-01 DOI:10.1016/j.jaapos.2024.103973

Rakan Algorinees MD , Abdulrahman Alhomoud MD , Ashwaq Al-Abeeri MD , Abdulrahman Al-Gaeed BSc , Priscilla Gikandi MPH , Rizwan Malik MD, PhD

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引用次数: 0

摘要

目的：评估一家三级眼科中心的儿科患者青光眼手术后发生脉络膜上腔出血（SCH）的风险因素：方法：回顾性审查2014年1月至2017年9月期间接受青光眼手术的326名患者（326只眼）的病历。17例SCH患者与同期接受青光眼手术的309例对照组患者进行了比较。我们记录了患者的年龄、性别、基线眼压、青光眼诊断、既往手术情况、术前轴位长度、眼球厚度、晶状体状态和青光眼手术类型（是否与白内障或其他青光眼手术合并进行或单独进行）：在17例SCH病例中，只有一例发生在术中，其余均发生在术后早期。最常见的诊断是原发性先天性青光眼（PCG），病例中有 10 例（59%），对照组中有 247 例（80%），其次是与非后天性眼部异常相关的青光眼，病例中有 3 例（18%），对照组中有 22 例（7%）。在单变量分析中发现，无晶体眼和联合手术可能是SCH发病的风险因素，但在多变量分析中均未发现显著性：在我们的研究队列中，合并手术和无晶体眼都可能是导致SCH的危险因素。

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Risk factors for suprachoroidal hemorrhage associated with glaucoma surgery in children: a case–control study

Purpose

To assess the risk factors for suprachoroidal hemorrhage (SCH) following glaucoma surgery in pediatric patients at a tertiary eye center.

Methods

The medical records of 326 patients (326 eyes) who underwent glaucoma surgery between January 2014, and September 2017 were reviewed retrospectively. Seventeen cases with SCH were compared with 309 controls who underwent uneventful glaucoma surgery during the same period. We documented age, sex, baseline intraocular pressure, glaucoma diagnosis, previous surgery, preoperative axial length, pachymetry, lens status and type of glaucoma surgery performed (whether combined with cataract or other glaucoma procedure or being standalone).

Results

Of the 17 cases of SCH, only a single case occurred intraoperatively; the remainder occurred in the early postoperative period. The most frequent diagnosis was primary congenital glaucoma (PCG), accounting for 10 patients (59%) in cases and 247 (80%) in controls, followed by glaucoma associated with nonacquired ocular anomalies, which accounted for 3 cases (18%) and 22 controls (7%). Aphakia and combined surgeries (in the univariate analysis) were found to be possible risk factors for the development of SCH, with none achieving significance in the multivariable analysis.

Conclusions

In our study cohort, combined surgeries as well aphakia were possible risk factors for SCH.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.