Journal of AaposPub Date : 2025-09-30DOI: 10.1016/j.jaapos.2025.104656
J Daniel Twelker, Andrew W Arthur, Rita Bhakta, Amy L Davis, Leslie K Dennis, Siomara G Enriquez, Kimberly D Gerhart, Chiu-Hsieh Hsu, M Sandra González Marshall, Jenifer Martin, Eileen R McGrath, Joseph M Miller, Divya Ramesh, Erin M Harvey
{"title":"Agreement between the Spot Vision Screener and cycloplegic retinoscopy for toddlers with astigmatism.","authors":"J Daniel Twelker, Andrew W Arthur, Rita Bhakta, Amy L Davis, Leslie K Dennis, Siomara G Enriquez, Kimberly D Gerhart, Chiu-Hsieh Hsu, M Sandra González Marshall, Jenifer Martin, Eileen R McGrath, Joseph M Miller, Divya Ramesh, Erin M Harvey","doi":"10.1016/j.jaapos.2025.104656","DOIUrl":"https://doi.org/10.1016/j.jaapos.2025.104656","url":null,"abstract":"<p><strong>Background: </strong>We investigated the agreement between the Spot Vision Screener (Welch Allyn) and gold standard cycloplegic retinoscopy in infants and toddlers, with special attention to astigmatism.</p><p><strong>Methods: </strong>Participants were children 12-35 months of age who failed a routine photoscreening using the Spot conducted at a recent well-child visit and who subsequently received a cycloplegic eye examination through the Spectacle Prescribing in Early Childhood Study (SPECS).</p><p><strong>Results: </strong>The final sample included 410 children, with an average age of 20.24 months. The Spot mean spherical equivalent value (M) was significantly less hyperopic than cycloplegic retinoscopy M (+0.35 D vs +0.80 D, t[409] < 0.001), and mean Spot Vision Screener cylinder (CYL) was significantly higher than cycloplegic retinoscopy CYL (1.84 D. vs 1.58 D, t[409] < 0.001).</p><p><strong>Conclusions: </strong>Cycloplegic retinoscopy found more hyperopic, or conversely, less myopic sphere power, in 60% of participants at the clinically significant level of >0.50 D. When using the Spot, this could result in under-referral to an eye care professional for moderate to high hyperopia. About 1 in 4 subjects showed higher clinically significant cylinder (>1.00 D) using the Spot compared with cycloplegic retinoscopy, which could result in over-referral for astigmatism when using the 2013 criteria for astigmatism.</p>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104656"},"PeriodicalIF":1.3,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2025-09-29DOI: 10.1016/j.jaapos.2025.104657
Alexander C Lieu, Evan H Walker, Shira L Robbins, David B Granet, Jolene Rudell
{"title":"Epidemiology of strabismus among adults in the United States: insights from the All of Us database.","authors":"Alexander C Lieu, Evan H Walker, Shira L Robbins, David B Granet, Jolene Rudell","doi":"10.1016/j.jaapos.2025.104657","DOIUrl":"https://doi.org/10.1016/j.jaapos.2025.104657","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the prevalence of adult-diagnosed strabismus and its associations with sex, age, and race in a large, diverse population database in the United States.</p><p><strong>Methods: </strong>Sex, age, and race data were collected from 413,457 individuals in the All of Us database. The χ<sup>2</sup> test with post hoc pairwise comparisons was used to determine significant differences in distributions of sex, age, and race data in 3,734 strabismus patients compared with the overall database.</p><p><strong>Results: </strong>There is a higher proportion of males among patients with strabismus compared with the overall database (43.34% vs 38.34% [P < 0.001]). There is a significantly higher proportion of patients aged over 65 years among patients with strabismus compared with the overall database (45.77% vs 24.7% [P < 0.001]). There is also a significantly different racial distribution of individuals with strabismus compared with the overall database (P < 0.001). Pairwise comparisons showed a significantly lower proportion of Asian individuals among patients with strabismus or heterotropia, a lower proportion of Black individuals with most subtypes, and a higher proportion of White individuals among patients with any strabismus.</p><p><strong>Conclusions: </strong>These results suggest that there is a lower proportion of females, Asian, and Black participants with diagnosed strabismus compared with the overall population in the All of Us database. These findings may indicate that strabismus affects patient populations differently, or that there is differential access to care and diagnosis of strabismus across sex, age, and race.</p>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104657"},"PeriodicalIF":1.3,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2025-09-29DOI: 10.1016/j.jaapos.2025.104655
Alexander C Lieu, Evan H Walker, Shira L Robbins, David B Granet, Jolene Rudell
{"title":"Socioeconomic trends of adult strabismus in the United States: an analysis of the All of Us database.","authors":"Alexander C Lieu, Evan H Walker, Shira L Robbins, David B Granet, Jolene Rudell","doi":"10.1016/j.jaapos.2025.104655","DOIUrl":"https://doi.org/10.1016/j.jaapos.2025.104655","url":null,"abstract":"<p><strong>Purpose: </strong>To determine associations of income and education level with a diagnosis of strabismus and to identify socioeconomic variables that may affect timely access to diagnosis.</p><p><strong>Methods: </strong>Annual income, high level of education completed, and ZIP code income, high school completion, poverty, and socioeconomic deprivation metrics were collected from 413,360 participants in the database. A χ<sup>2</sup> test was used to determine significant differences in distributions of income, education, and ZIP code metrics in 3,734 strabismus patients compared with the overall database.</p><p><strong>Results: </strong>Participants living in ZIP codes with lower multidimensional deprivation indices (less deprivation) are more likely to be diagnosed with strabismus. Participants with annual income below $10,000 (10.10%) or who completed education between fifth grade and a high school diploma or GED (20.06%) are less likely to receive a diagnosis for certain strabismus subtypes. Participants with annual income over $200,000 (7.07%), advanced degrees (27.02%), living in ZIP codes with higher income, and higher high school completion rates were more likely to be diagnosed with certain strabismus subtypes.</p><p><strong>Conclusions: </strong>Participants diagnosed with strabismus tend to have higher incomes, an advanced degree, and reside in more affluent ZIP codes, whereas those with lower income and education levels are less likely to be diagnosed. These findings reveal potential socioeconomic disparities in access to ophthalmic diagnostic services and care. Findings emphasize the importance of addressing socioeconomic barriers in eye care to enable equitable access.</p>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104655"},"PeriodicalIF":1.3,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145208123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2025-09-26DOI: 10.1016/j.jaapos.2025.104654
Jenny Chun Ling Kuo, Xinxing Guo, Megan E Collins
{"title":"Phased multimodal consent in a Baltimore school-based vision program: a novel approach.","authors":"Jenny Chun Ling Kuo, Xinxing Guo, Megan E Collins","doi":"10.1016/j.jaapos.2025.104654","DOIUrl":"https://doi.org/10.1016/j.jaapos.2025.104654","url":null,"abstract":"<p><p>Obtaining parental consent is a crucial step for students to receive eye examinations in school-based vision programs (SBVPs). Using paper consent forms is challenging and may limit responses. We explored a novel, phased, multimodal consent approach in a Baltimore SBVP to increase program participation during the 2022-23 school year. Vision screenings were provided for all students as part of the program. Consent outreach was conducted for all students prior to vision screening (universal phase) and again after for students who failed a vision screening (targeted phase). Email consent only was used during the universal phase, whereas a tiered approach that combined email, paper, and telephone was used in the targeted phase. Of the 46 schools that implemented multimodal consenting, the mean overall consent response rate was 86% ± 9.3% (range, 62%-99%). Mean universal and targeted consent response rate was 15% (95% CI, 13%-18%) and 71% (95% CI, 68%-74%), respectively. Among targeted consent responses, 10% were obtained by email, 26% by paper, and 64% by telephone.</p>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104654"},"PeriodicalIF":1.3,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2025-09-26DOI: 10.1016/j.jaapos.2025.104653
Veronika Yehezkeli, Stacy L Pineles, Federico G Velez
{"title":"Fibrotic bands in thyroid eye disease: a contributing factor to persistent postoperative restriction.","authors":"Veronika Yehezkeli, Stacy L Pineles, Federico G Velez","doi":"10.1016/j.jaapos.2025.104653","DOIUrl":"https://doi.org/10.1016/j.jaapos.2025.104653","url":null,"abstract":"<p><p>Accessory extraocular fibrous bands are orbital structures that are typically symptomatic in patients with congenital cranial dysinnervation disorders. However, orbital imaging studies have documented asymptomatic accessory extraocular fibrous in individuals without strabismus. The role of preexisting symptomatic fibrotic bands in causing persistent restrictive strabismus in patients with acquired strabismus and the possibility that inflammatory conditions affecting the extraocular muscles could also affect those bands is rarely discussed. We present 2 cases of thyroid eye disease (TED) in which asymptomatic bands likely became clinically significant with progression of TED. Both patients developed restrictive strabismus and underwent strabismus surgery. Both showed persistent positive forced duction tests (FDT) despite muscle disinsertion. Intraoperative identification and excision of fibrotic bands led to normalization of the FDT and improved surgical outcomes. These bands may contribute to atypical motility patterns in TED.</p>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104653"},"PeriodicalIF":1.3,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2025-09-21DOI: 10.1016/j.jaapos.2025.104652
Sowmya Raveendra Murthy, Sahil Sharma
{"title":"Modified Nishida's procedure combined with medial rectus recession in a case of Moebius syndrome.","authors":"Sowmya Raveendra Murthy, Sahil Sharma","doi":"10.1016/j.jaapos.2025.104652","DOIUrl":"https://doi.org/10.1016/j.jaapos.2025.104652","url":null,"abstract":"","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104652"},"PeriodicalIF":1.3,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145132207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2025-09-20DOI: 10.1016/j.jaapos.2025.104650
Juan Sanchez, Kimberly Gerhart, Andrew W Arthur, Erin Harvey, John D Twelker, Chiu-Hsieh Hsu, Leslie K Dennis, Joseph M Miller
{"title":"Vision and developmental delay in toddlers.","authors":"Juan Sanchez, Kimberly Gerhart, Andrew W Arthur, Erin Harvey, John D Twelker, Chiu-Hsieh Hsu, Leslie K Dennis, Joseph M Miller","doi":"10.1016/j.jaapos.2025.104650","DOIUrl":"10.1016/j.jaapos.2025.104650","url":null,"abstract":"<p><p>Research investigating an association between vision impairment and toddlers' ability to reach developmental milestones is sparse. Medical records of children 11-37 months of age who had automated vision screening were retrospectively reviewed to evaluate whether such an association was present. A lower likelihood of development delay was associated with female sex and Hispanic patients. However, developmental delay diagnosis was not associated with failing automated vision screening.</p>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104650"},"PeriodicalIF":1.3,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2025-09-19DOI: 10.1016/j.jaapos.2025.104649
R Michael Siatkowski
{"title":"How Do We Fix This Mess?","authors":"R Michael Siatkowski","doi":"10.1016/j.jaapos.2025.104649","DOIUrl":"https://doi.org/10.1016/j.jaapos.2025.104649","url":null,"abstract":"","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104649"},"PeriodicalIF":1.3,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2025-09-19DOI: 10.1016/j.jaapos.2025.104651
Benjamin K J Host, Aban Bahabri, Sarah Alexander, Kamiar Mireskandari
{"title":"Uveal involvement as the presenting sign of recurrence of systemic B-cell lymphoma: a case report and description of biopsy technique.","authors":"Benjamin K J Host, Aban Bahabri, Sarah Alexander, Kamiar Mireskandari","doi":"10.1016/j.jaapos.2025.104651","DOIUrl":"https://doi.org/10.1016/j.jaapos.2025.104651","url":null,"abstract":"<p><p>The uvea is a rare site for primary or recurrent lymphoma, but it is a potentially sight- and life-threatening pediatric presentation. The differential diagnosis is broad, and tissue biopsy is necessary for confirmation and appropriate management. We present the first published case of relapsed atypical B-cell lymphoma with KMT2A gene rearrangement involving the iris. Despite a high index of clinical suspicion of recurrent systemic lymphoma, biopsy of aqueous was nondiagnostic. The child required further aqueous sampling and iris biopsy, which confirmed the diagnosis and allowed for appropriate treatment. Pearls for acquiring a representative aqueous biopsy, as well as a surgical video describing aqueous and iris biopsy technique are provided.</p>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104651"},"PeriodicalIF":1.3,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145114770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of AaposPub Date : 2025-09-18DOI: 10.1016/j.jaapos.2025.104638
John E Williamson, Laurel Lam, Nina R Spitofsky, Alexandra R Zaloga, Sudheshna Vemula, Gabriella Baldassarre, Sara Flanagan, Rebecca J Elias, Bruce M Schnall, Kammi B Gunton, Barry N Wasserman
{"title":"Post-pandemic changes in demographics and outcomes of children at an inner-city vision outreach program: Give Kids Sight Day.","authors":"John E Williamson, Laurel Lam, Nina R Spitofsky, Alexandra R Zaloga, Sudheshna Vemula, Gabriella Baldassarre, Sara Flanagan, Rebecca J Elias, Bruce M Schnall, Kammi B Gunton, Barry N Wasserman","doi":"10.1016/j.jaapos.2025.104638","DOIUrl":"https://doi.org/10.1016/j.jaapos.2025.104638","url":null,"abstract":"<p><strong>Purpose: </strong>To characterize how pediatric screening demographic characteristics changed after the COVID-19 pandemic in children attending Give Kids Sight Day (GKSD), a free vision screening program in Philadelphia.</p><p><strong>Methods: </strong>Three data sets were analyzed: (1) prospective survey from guardians attending GKSD 2023, (2) retrospective analysis of GKSD attendee records, and (3) pre-pandemic (2009-2020) GKSD data.</p><p><strong>Results: </strong>A total of 293 children attended GKSD in 2023, and 189 surveys were completed. Compared with pre-pandemic GKSD events, there were more repeat participants (15% to 26% [P < 0.001]), greater percentage uninsured (26%-27% to 38% [P < 0.001]), and more insured without vision coverage (30% to 46% [P = 0.002]). More children required refractive correction (28%-61% to 76% [P < 0.001]) and subsequent follow-up (10%-15% to 17% [P = 0.004]). Of children receiving their first pair of glasses, 47% had not failed a previous vision screening. Ninety-one percent of missed appointments were for first-time attendees. Eye-care-naive attendees commonly learned of GKSD from school (59%). Perceived barriers to care were diverse and equally distributed among respondents.</p><p><strong>Conclusions: </strong>Since the COVID-19 pandemic, insurance coverage for vision care has declined, with rising unmet ophthalmic needs in event attendees. Many children with refractive pathology had never failed prior school-based vision screening, suggesting lapses in current screening systems. School-based initiatives, funding, and community social worker support are needed to connect eye-care-naive patients with ophthalmic care, ensure community screening is completed effectively, and connect families to subsidized insurance plans.</p>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":" ","pages":"104638"},"PeriodicalIF":1.3,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145103145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}