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IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-06-01 DOI: 10.1016/S1091-8531(24)00223-4

引用次数: 0

Publication rates of registered strabismus trials from ClinicalTrials.gov 来自 ClinicalTrials.gov 的注册斜视试验发表率。

IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-06-01 DOI: 10.1016/j.jaapos.2024.103936

Leo Meller BS , Angel Bert Sambo BS , Nam Nguyen , Shira L. Robbins MD , David B. Granet MD

引用次数: 0

Modernizing the evaluation of infantile nystagmus: the role of handheld optical coherence tomography 婴儿眼球震颤评估的现代化：手持式光学相干断层扫描的作用。

IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-06-01 DOI: 10.1016/j.jaapos.2024.103924

Suzanna Joseph BS, Rizul Naithani DO, MPH, Samuel Alvarez MD, Tanya Glaser MD, Sharon Freedman MD, Mays El-Dairi MD

{"title":"Modernizing the evaluation of infantile nystagmus: the role of handheld optical coherence tomography","authors":"Suzanna Joseph BS, Rizul Naithani DO, MPH, Samuel Alvarez MD, Tanya Glaser MD, Sharon Freedman MD, Mays El-Dairi MD","doi":"10.1016/j.jaapos.2024.103924","DOIUrl":"10.1016/j.jaapos.2024.103924","url":null,"abstract":"<div><h3>Background</h3><p>Infantile nystagmus syndrome can be associated with an afferent problem (anterior or posterior segment) or constitute an isolated idiopathic disorder. With a normal ophthalmic examination, current guidelines recommend electroretinography (ERG) rather than magnetic resonance (MRI) for preliminary workup. Given the limited use of optical coherence tomography (OCT) in preverbal children, the purpose of this study was to evaluate the role of handheld OCT (HH-OCT) in the initial diagnostic evaluation of infantile nystagmus.</p></div><div><h3>Methods</h3><p>In this cross-sectional case series, the medical records of all children with infantile nystagmus and HH-OCT imaging at the Duke Eye Center from August 2016 to July 2021 were retrospectively reviewed. Children with anterior segment disorders or obvious retina/optic nerve structural pathology, bilateral ophthalmoplegia, or Down syndrome were excluded. Two masked pediatric ophthalmologists graded HH-OCT images for optic nerve head and macular abnormalities. A neuro-ophthalmologist reviewed clinical findings of each patient’s presenting visit and recommended appropriate testing (MRI vs ERG), initially without, and again with HH-OCT image review.</p></div><div><h3>Results</h3><p>A total of 39 cases were included, with mean presenting age of 1.3 years. Final diagnoses included retinal or foveal abnormalities (7), optic nerve pathology (13), idiopathic (10), or unknown (9). HH-OCT findings included optic nerve hypoplasia (1), optic nerve elevation (3), persistence of the inner layers at the fovea (9), thin ganglion cell layer (8), ellipsoid zone abnormality (3), and thin choroid (1). HH-OCT findings altered initial clinical-only management in 16 cases (41%), including avoiding MRI (5) and ERG (10) testing.</p></div><div><h3>Conclusions</h3><p>Our results suggest that HH-OCT has the potential to augment and streamline the evaluation of infantile nystagmus.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous collapse of an iris stromal cyst in a young child 一名幼儿的虹膜基质囊肿自发破溃。

IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-06-01 DOI: 10.1016/j.jaapos.2024.103916

Nathalie E. Perez BS , Sugi Panneerselvam MD , Ta Chen Peter Chang MD , Kara M. Cavuoto MD , Zelia Maria Correa MD, PhD , Michelle M. Falcone MD

{"title":"Spontaneous collapse of an iris stromal cyst in a young child","authors":"Nathalie E. Perez BS , Sugi Panneerselvam MD , Ta Chen Peter Chang MD , Kara M. Cavuoto MD , Zelia Maria Correa MD, PhD , Michelle M. Falcone MD","doi":"10.1016/j.jaapos.2024.103916","DOIUrl":"10.1016/j.jaapos.2024.103916","url":null,"abstract":"<div><p>A 4-month-old girl was referred for evaluation of an anterior chamber cyst in the left eye. Examination under anesthesia (EUA) revealed a large iris stromal cyst in the anterior chamber involving the angle and the pupillary border, with touch of the corneal endothelium and anterior lens capsule. Intraocular pressure was normal. There was no anisometropic refractive error by retinoscopy. Close observation with amblyopia management was recommended as the pupil was only partially occluded by the cyst, and there was a clear red reflex around the cyst. Repeat EUA 6 months following diagnosis showed spontaneous collapse of the cyst. There was no recurrence noted at her most recent follow-up, 2 years after presentation, and most of the pupillary axis remains unobstructed by the cyst. The patient continues to be followed to monitor for possible cyst progression, anisometropia, and development of amblyopia. Though rare, spontaneous resolution of an iris stromal cyst may occur and thus, observation may be considered, particularly if the cyst is not causing anterior segment complications or obstruction of the visual axis.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140860027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Doses of medial rectus muscle recessions for divergence insufficiency-type esotropia 内侧直肌凹陷治疗发散不全型内斜视的剂量。

IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-06-01 DOI: 10.1016/j.jaapos.2024.103905

Aaron M. Miller MD , Jonathan M. Holmes BM, BCh , Rui Wu MS , Raymond T. Kraker MSPH , Eric R. Crouch MD , Katherine A. Lee MD , Monte A. Del Monte MD , Justin D. Marsh MD , Courtney L. Kraus MD , David K. Wallace MD, MPH , Jeffrey D. Colburn MD , Pavlina S. Kemp MD , Susan A. Cotter OD, MS , Pediatric Eye Disease Investigator Group (PEDIG)

{"title":"Doses of medial rectus muscle recessions for divergence insufficiency-type esotropia","authors":"Aaron M. Miller MD , Jonathan M. Holmes BM, BCh , Rui Wu MS , Raymond T. Kraker MSPH , Eric R. Crouch MD , Katherine A. Lee MD , Monte A. Del Monte MD , Justin D. Marsh MD , Courtney L. Kraus MD , David K. Wallace MD, MPH , Jeffrey D. Colburn MD , Pavlina S. Kemp MD , Susan A. Cotter OD, MS , Pediatric Eye Disease Investigator Group (PEDIG)","doi":"10.1016/j.jaapos.2024.103905","DOIUrl":"10.1016/j.jaapos.2024.103905","url":null,"abstract":"<div><p>We evaluated whether doses of bilateral medial rectus recessions greater than Parks’s tables yielded superior outcomes for adult-onset divergence insufficiency. Forty-two patients underwent bilateral medial rectus recessions. Dose was analyzed as the average total per muscle (surgery + suture adjustment if performed) and compared with the standard dose tables (based on preoperative distance esodeviation), as difference between dose performed and dose indicated by Parks’s tables. Each participant was classified as having received either Parks’s dose (within 0.5 mm) or a dose greater than Parks’s dose. Success was defined as “rarely” or “never” diplopia in distance straight-ahead gaze and reading. For patients classified as success, the mean difference between actual surgical dose performed and Parks’s dose was calculated. Success was 91% (29/32) in those receiving greater than Parks’s dose versus 67% (6/9) with Parks’s dose (difference = 24%; 95% CI, −5% to 60%). The mean surgical dose was 1.0 mm greater than Parks’s tables for the 35 successes (at 10 weeks) versus 0.7 mm greater for the 6 failures (difference = 0.4 mm; 95% CI, −0.2 to 0.9). For medial rectus recessions in adult-onset divergence insufficiency-type esotropia, a surgical dose 1 mm greater than Parks’s tables, for each muscle, is a reasonable strategy.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of simultaneous prism and cover test (SPCT) and prism and alternate cover test (PACT) measurements with final power of Press-On prism power dispensed 同时棱镜和盖板测试 (SPCT) 和棱镜和交替盖板测试 (PACT) 测量结果与压入式棱镜最终功率分配的比较。

IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-06-01 DOI: 10.1016/j.jaapos.2024.103918

Alex Christoff CO, COT

{"title":"Comparison of simultaneous prism and cover test (SPCT) and prism and alternate cover test (PACT) measurements with final power of Press-On prism power dispensed","authors":"Alex Christoff CO, COT","doi":"10.1016/j.jaapos.2024.103918","DOIUrl":"10.1016/j.jaapos.2024.103918","url":null,"abstract":"<div><h3>Purpose</h3><p>To investigate the association of strabismic angle obtained by simultaneous prism and cover test (SPCT) and prism alternate cover test (PACT) with the final power of Press-On prism used in adults with symptomatic strabismus.</p></div><div><h3>Methods</h3><p>The medical records of consecutive patients seen by a single orthoptist at an urban, tertiary care hospital over a 36-month period were reviewed retrospectively. All subjects had been prescribed Press-On prism for diplopia after evaluation with SPCT and PACT measurements at distance fixation. Prism dispensed was chosen by the patient using a trial Press-On prism set.</p></div><div><h3>Results</h3><p>A total of 244 charts were reviewed. Of these, 108 adult patients had prism dispensed, and 32 had both SPCT and PACT measurements. Mean SPCT measurement was 7<sup>Δ</sup> (median, 6<sup>Δ</sup>; range, 3<sup>Δ</sup>-14<sup>Δ</sup>); mean PACT, 13<sup>Δ</sup> (median, 11<sup>Δ</sup>; range, 8<sup>Δ</sup>-20<sup>Δ</sup>). The mean prism power dispensed was 7<sup>Δ</sup> (median, 6<sup>Δ</sup>; range, 1<sup>Δ</sup>-15<sup>Δ</sup>); this was not significantly different from mean SPCT (<em>P</em> = 0.35). There was a large difference (6<sup>Δ</sup>) between mean PACT measurements and mean prism dispensed (<em>P</em> < 0.001). At follow-up of 1 year, 21 patients (66%) remained in prism. Nine patients (4%) elected to undergo eye muscle surgery, 7 with horizontal strabismus, 6 of whom had SPCT measurements of >10<sup>Δ</sup> and PACT measurements of >15<sup>Δ</sup>.</p></div><div><h3>Conclusions</h3><p>Press-On prism power used was more closely tied to the angle of strabismus obtained by SPCT. Overall success rate of Press-On prism was good when the prism power dispensed was close to the SPCT measurement, suggesting that it is reasonable to initiate treatment with a weaker prism, approximating the SPCT measurement, building up only if there are continuing symptoms.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral tonic pupils secondary to anti-GD2 antibody therapy for neuroblastoma 继发于神经母细胞瘤抗GD2抗体治疗的双侧强直性瞳孔。

IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-04-01 DOI: 10.1016/j.jaapos.2024.103852

Christopher M. Edwards BS , Daniel Elefant MD , Michael S. Isakoff MD , Majida A. Gaffar MD

引用次数: 0

Surgical management of oculomotor nerve palsy: a comparison of lateral rectus deactivation combined with either medial rectus resection or medial rectus fixation to the medial palpebral ligament 眼球运动神经麻痹的手术治疗：外侧直肌失活联合内侧直肌切除术与内侧直肌固定于内侧睑韧带的比较。

IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-04-01 DOI: 10.1016/j.jaapos.2024.103871

Shashikant Shetty MS , Marushka Aguiar MS , Gargi Shah MS , Monisha Mohan MS , P. Vijayalakshmi MS , R. Janani MS

{"title":"Surgical management of oculomotor nerve palsy: a comparison of lateral rectus deactivation combined with either medial rectus resection or medial rectus fixation to the medial palpebral ligament","authors":"Shashikant Shetty MS , Marushka Aguiar MS , Gargi Shah MS , Monisha Mohan MS , P. Vijayalakshmi MS , R. Janani MS","doi":"10.1016/j.jaapos.2024.103871","DOIUrl":"10.1016/j.jaapos.2024.103871","url":null,"abstract":"<div><h3>Purpose</h3><p>To analyze and compare the outcome of two different surgical procedures in patients with complete oculomotor nerve palsy with large-angle exotropia.</p></div><div><h3>Methods</h3><p>The medical records of patients with total oculomotor nerve palsy and large-angle exotropia operated on at a single center from January 2006 to June 2020 were reviewed retrospectively. One group underwent lateral rectus deactivation with medial rectus resection (resection group); the other group underwent lateral rectus deactivation with medial rectus fixation to the medial palpebral ligament (fixation group). Surgical outcomes on the first postoperative day and at 6 months postoperatively were analyzed, including alignment and postoperative complications. All statistical analyses were performed using STATA version 14. A <em>P</em> value of <0.05 was considered significant.</p></div><div><h3>Results</h3><p>A total of 35 patients were included. There was a trend toward greater surgical success in the fixation group (93%) than in the resection group (65%), but these results were not statistically significant. Postoperative exotropic drifts were noted in both the procedures but tended to be more with patients in the resection group. Postoperative complications were noted only in the fixation group.</p></div><div><h3>Conclusions</h3><p>Lateral rectus deactivation with medial rectus fixation to the medial palpebral ligament requires more time and greater surgical expertise but appears to better prevent postoperative exotropic drift compared with lateral rectus deactivation combined with medial rectus resection.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140068892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-04-01 DOI: 10.1016/S1091-8531(24)00178-2

引用次数: 0

Peripheral retinal finding on fluorescein angiography in neuronal ceroid lipofuscinosis type 2 (CLN2) 2 型神经元类钙化脂褐质沉着症（CLN2）荧光素血管造影的周边视网膜发现。

IF 1.6 4区医学

Journal of Aapos Pub Date : 2024-04-01 DOI: 10.1016/j.jaapos.2024.103830

David L. Rogers MD , Emily De Los Reyes MD , Thomas A. Mendel MD, PhD , Brian Caprul , Sarah Podlasiak RN , Catherine O. Jordan MD

引用次数: 0