白内障手术后儿童青光眼的视觉和手术效果。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-10-01 DOI:10.1016/j.jaapos.2024.103993

Adam Jacobson MD , Brenda L. Bohnsack MD, PhD

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引用次数: 0

摘要

目的：评估白内障手术后青光眼（GFCS）的手术频率和治疗后效果：方法：回顾性审查白内障手术后青光眼患者的病历。方法：对 GFCS 患者的病历进行回顾性审查，收集晶体切除术和青光眼手术的详细信息以及最终检查结果。纳入标准包括有晶状体切除术史：在 127 名 GFCS 患者（66 名男性，58 名双侧病例）的 169 只眼睛中，73 名患者（57%）的 88 只眼睛（52%）接受了青光眼手术（首次接受青光眼手术的年龄中位数为 3.5 岁；两次青光眼手术的中位数）。最后随访时（平均 13.6 ± 7.0 年），需要进行青光眼手术的眼睛视力较差（P = 0.01），杯盘比较大（P < 0.01）。与单侧先天性白内障患者相比，有双侧先天性白内障病史的 GFCS 患者的患眼视力更好（P < 0.01）。开眼角手术（56 例）、Baerveldt 装置（38 例）、Ahmed 瓣膜（19 例）和环形消融术（21 例）的 1 年存活率介于 64% 和 75% 之间。Baerveldt植入体的5年和10年存活率最高，分别为65%和43%：结论：在我们的研究队列中，50% 以上的 GFCS 患者至少需要进行一次青光眼手术。青光眼手术和单侧白内障病史与较差的视力结果有关。

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Visual and surgical outcomes of childhood glaucoma following cataract surgery

Purpose

To evaluate frequency of surgery and post-treatment outcomes in glaucoma following cataract surgery (GFCS).

Methods

The medical records of patients with GFCS were reviewed retrospectively. Lensectomy and glaucoma surgery details and final examination findings were collected. Inclusion criteria included history of lensectomy at <1 year of age, diagnosis of glaucoma, and at least 1 year of follow-up.

Results

Of 169 eyes of 127 GFCS patients (66 male, 58 bilateral cases), 88 eyes (52%) of 73 (57%) patients underwent glaucoma surgery (median, 3.5 years of age at first glaucoma surgery; median of two glaucoma surgeries). At final follow-up (mean, 13.6 ± 7.0 years), eyes requiring glaucoma surgery had worse visual acuity (P = 0.01) and greater cup:disk ratio (P < 0.01). GFCS patients with history of bilateral congenital cataracts had better visual acuity in affected eyes than those with history of unilateral congenital cataract (P < 0.01). Angle surgery (n = 56), Baerveldt devices (n = 38), Ahmed valves (n = 19), and cycloablation (n = 21) showed 1-year survival rates between 64% and 75%. Baerveldt implants showed the highest 5- and 10-year survival rates, at 65% and 43%, respectively.

Conclusions

More than 50% of eyes with GFCS in our study cohort required at least one glaucoma surgery. Glaucoma surgery and history of unilateral cataract were associated with worse visual acuity outcomes.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.