Journal of Aapos最新文献

{"title":"Adams-Oliver syndrome associated with refractory glaucoma","authors":"","doi":"10.1016/j.jaapos.2024.103950","DOIUrl":"10.1016/j.jaapos.2024.103950","url":null,"abstract":"<div><p><span>Adams-Oliver syndrome (AOS) is a rare inherited disorder characterized by aplasia cutis congenita<span>, cutis marmorata telangiectatica congenita, and terminal </span></span>limb defects<span>. Ocular associations have been rarely reported. We report a 6-month-old boy with AOS associated with refractory glaucoma, megalocornea, and anterior polar cataract. To our knowledge, this is the first case of glaucoma to be reported in association with AOS.</span></p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary household transmission of conjunctivitis in children","authors":"","doi":"10.1016/j.jaapos.2024.103953","DOIUrl":"10.1016/j.jaapos.2024.103953","url":null,"abstract":"<div><p><span><span>Among surveyed households, the transmission rate of pediatric<span> conjunctivitis was 12%. Rates did not differ when the index child did or did not use an </span></span>ophthalmic<span> antibiotic (14% vs 11% [</span></span><em>P</em> = 0.6]). Transmission rates were lower than for other infections where children are not routinely excluded from school or daycare.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141318819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of spontaneous hyphema secondary to gestational alloimmune liver disease","authors":"","doi":"10.1016/j.jaapos.2024.103957","DOIUrl":"10.1016/j.jaapos.2024.103957","url":null,"abstract":"<div><p><span>Hyphema<span> is rarely seen in neonates. Although most cases are secondary to instrument-assisted delivery, neonatal hyphema can occur spontaneously or result from an underlying coagulopathy. We report the case of an infant who was born with unilateral hyphema and was subsequently found to have gestational alloimmune liver disease—a condition where </span></span>maternal antibodies<span> attack the infant’s liver, leading to a hypocoagulable state<span>. Our patient was treated with topical prednisolone and cyclopentolate/phenylephrine, with subsequent resolution of the hyphema.</span></span></p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual acuity and optic nerve size assessed by magnetic resonance imaging in optic nerve hypoplasia","authors":"","doi":"10.1016/j.jaapos.2024.103964","DOIUrl":"10.1016/j.jaapos.2024.103964","url":null,"abstract":"<div><p><span><span>We investigated the relationship between optic nerve (ON) size and visual acuity in children with </span>optic nerve hypoplasia<span> (ONH). The medical records of patients &lt;19 years with ONH who underwent brain magnetic resonance imaging (MRI) and visual acuity assessment were reviewed. ON diameter at orbital and cisternal segments was assessed independently by two neuroradiologists and compared with visual acuity. ON diameter &lt;1.7 mm represented a cutoff, below which was significantly associated with visual acuity of 20/200 or worse (</span></span><em>P</em> = 0.04) and above which was significantly associated with visual acuity of 20/40 or better (<em>P</em> = 0.004). ON diameter measured with MRI may provide an early prognostic indication of visual potential for children with ONH.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141494105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Myopia trends among children and adolescents: a nationwide study in South Korea","authors":"","doi":"10.1016/j.jaapos.2024.103969","DOIUrl":"10.1016/j.jaapos.2024.103969","url":null,"abstract":"<div><h3>Purpose</h3><p>To evaluate gender disparities in the progression of myopia among children and adolescents in South Korea.</p></div><div><h3>Methods</h3><p>Nationwide cross-sectional data of 1,190 subjects aged 10-18 years was obtained for the years of 2011 (baseline) and 2021 using the Korea National Health and Nutrition Examination Surveys. The prevalence of myopia, as well as data regarding age, household income, height, weight, body mass index, and age of menarche, were evaluated. Myopia was defined as a spherical equivalent (SE) ≤ −0.5 D.</p></div><div><h3>Results</h3><p>The prevalence of myopia among boys was stable in 2021 compared to 2011, with rates of 53.7% and 52.8%, respectively (<em>P</em> = 0.372). Among girls, however, there was a statistically significant increase in myopia prevalence in 2021 compared to 2011, with rates of 73.7% and 51.6% (<em>P</em> &lt; 0.001), respectively. Over 10 years, the adjusted prevalence ratio for myopia in boys was 1.11 (95% CI, 0.77-1.61), whereas myopia prevalence in girls underwent a 1.87-fold increase over the same period (95% CI, 1.30-2.69), and menarche at 12 years of age or older was associated with less myopia in girls (PR = 0.84; 95% CI, 0.72-0.99). The spherical equivalent refraction in girls increased significantly over the same 10-year period, from −1.09 ± 0.13 D to −1.58 ± 0.17 D (<em>P</em> &lt; 0.017), whereas in boys, there was no significant difference (<em>P</em> = 0.604).</p></div><div><h3>Conclusions</h3><p>In our study cohort, the prevalence of myopia increased significantly among girls compared with boys over the course of decade. Additionally, an association between early menarche in girls and the prevalence of myopia was observed.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141602007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of teprotumumab infusion on ocular alignment in patients with symptomatic thyroid eye disease","authors":"","doi":"10.1016/j.jaapos.2024.103959","DOIUrl":"10.1016/j.jaapos.2024.103959","url":null,"abstract":"<div><h3>Background</h3><p><span><span>Thyroid eye disease (TED) can result in </span>proptosis<span> and ocular misalignment, leading to eye pain, diplopia, and </span></span>vision loss<span>. Teprotumumab, a humanized antibody against insulin-like growth factor 1 receptor, was approved in 2020 for the treatment of TED. The purpose of this study was to describe the effect of a full course of teprotumumab on ocular misalignment.</span></p></div><div><h3>Methods</h3><p>The medical records<span> of patients who underwent treatment with teprotumumab for active moderate-to-severe TED at a single institution from April 2020 to September 2023 were reviewed retroactively. Sensorimotor examination was performed at each visit using simultaneous prism-cover testing. Demographic information and previous history of radioactive iodine<span>, steroids, strabismus surgery, and smoking were extracted from the record for analysis.</span></span></p></div><div><h3>Results</h3><p><span>A total of 19 patients were treated during the study period, of whom 11 had strabismus and diplopia. The initial absolute horizontal misalignment in these 11 was 6.0</span>^Δ ± 1.5^Δ, vertical misalignment was 7.7^Δ ± 2.4^Δ, and total misalignment was 11.5^Δ ± 2.0^Δ. On completion of treatment, these measurements decreased by 2.0^Δ ± 1.5^Δ, 2.2^Δ ± 1.0^Δ, and 3.2^Δ ± 1.6^Δ, respectively (<em>P</em> = 0.10, 0.02, and 0.04, resp.). Eight patients (73%) had a decrease in their strabismus, and 5 (46%) reported complete resolution of their diplopia at the final visit. No factors were predictive of which patients would have resolution of their misalignment. Of the remaining 3 patients who had no improvement in ocular alignment, 2 (66%) underwent strabismus surgery. Of the 8 patients with improvement of strabismus, only a single patient (13%) underwent strabismus surgery for persistent diplopia.</p></div><div><h3>Conclusions</h3><p>In our study cohort, a full course of teprotumumab coincided with complete resolution of diplopia in 46% of patients and a decrease in strabismus in 73% of patients.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141472118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous recovery from amblyopia following fellow eye vision loss: a systematic review and narrative synthesis","authors":"Madison P. Echavarri-Leet BA ,&nbsp;Hannah H. Resnick MD, MPhil ,&nbsp;Daniel A. Bowen BA ,&nbsp;Deborah Goss MLS, MA ,&nbsp;Mark F. Bear PhD ,&nbsp;Eric D. Gaier MD, PhD","doi":"10.1016/j.jaapos.2024.103971","DOIUrl":"10.1016/j.jaapos.2024.103971","url":null,"abstract":"<div><h3>Background</h3><p>The effectiveness of traditional amblyopia therapies is largely restricted to childhood. However, spontaneous recovery in adulthood is possible following vision loss in the fellow eye due to enucleation, injury, or disease. The twofold purpose of this study was (1) to define the incidence of recovery and (2) to elucidate the clinical features associated with greater amblyopic eye gains.</p></div><div><h3>Methods</h3><p>A systematic review of three databases yielded 24 reports containing 110 cases of patients ≥18 years old with unilateral amblyopia and vision-limiting fellow eye pathology.</p></div><div><h3>Results</h3><p>Our analysis revealed that 25 of 42 of adult patients (59.5%) gained ≥2 logMAR lines in the amblyopic eye after fellow eye vision loss. The degree of improvement is clinically meaningful (median, 2.6 logMAR lines). Recovery occurs within 12 months of initial loss of fellow eye vision. Regression analysis demonstrated that younger age, worse baseline visual acuity in the amblyopic eye, and worse vision in the fellow eye independently conferred greater gains in amblyopic eye visual acuity. Recovery occurs across amblyopia types and fellow eye pathologies, although disease entities affecting fellow eye retinal ganglion cells demonstrate shorter latencies to recovery.</p></div><div><h3>Conclusions</h3><p>Amblyopia recovery after fellow eye injury demonstrates that the adult brain harbors the neuroplastic capacity for clinically meaningful recovery, which could potentially be harnessed by novel approaches to treat adults with amblyopia.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 49th Annual Meeting of the American Association for Pediatric Ophthalmology and Strabismus, Austin, Texas, April 7-11, 2024","authors":"","doi":"10.1016/j.jaapos.2024.103972","DOIUrl":"10.1016/j.jaapos.2024.103972","url":null,"abstract":"","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anterior segment optical coherence tomography (AS-OCT) in strabismus following trauma","authors":"","doi":"10.1016/j.jaapos.2024.103955","DOIUrl":"10.1016/j.jaapos.2024.103955","url":null,"abstract":"<div><p><span>We describe 3 cases of ocular trauma that presented with strabismus. Anterior segment optical coherence tomography was used to delineate the morphology of </span>extraocular muscle insertions and proved helpful in diagnosis and management.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141321923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors associated with pediatric ophthalmology follow-up adherence before and during the COVID-19 pandemic","authors":"","doi":"10.1016/j.jaapos.2024.103963","DOIUrl":"10.1016/j.jaapos.2024.103963","url":null,"abstract":"<div><h3>Background</h3><p>Studies describe poor follow-up among children in ophthalmology prior to the COVID-19 pandemic. Although the pandemic led to worse adherence for routine medical care in children, little information exists on pediatric ophthalmology follow-up adherence during COVID-19. The purpose of this study was to evaluate the effect of the COVID-19 pandemic on follow-up adherence for children with eye disease, and identified characteristics associated with follow-up adherence.</p></div><div><h3>Methods</h3><p>In this single-center study, the medical records of 519 new pediatric (≤18 years of age) patients seen during January, April, August, and December 2019 and 2021 were reviewed retrospectively. Patients were classified into two groups: adherent (patients who followed up within 30 days of recommended appointment time) or less-adherent (patients who followed up &gt;30 days after recommended follow-up or never). Main outcome measure was patient adherence status.</p></div><div><h3>Results</h3><p>Follow-up adherence was similar before and during the COVID-19 pandemic (50.4% for 2019 and 49.6% for 2021 [<em>P</em> = 0.40]). Patients that were less likely to be adherent in both univariate and multivariable analyses included those with public insurance (adjusted OR = 0.63 [95% CI, 0.40-1.00]; <em>P</em> = 0.05), and those recommended to follow-up ≥3 months (adjusted OR ≤ 0.10; <em>P</em> &lt; 0.001). In addition, in univariate analysis, those who declined to self-report race (OR = 0.53 [95% CI, 0.29-0.95]; <em>P</em> = 0.04) and those seen by optometrists (OR = 0.42 [95% CI, 0.29-0.60]; <em>P</em> &lt; 0.001) were less likely to be adherent, while patients who traveled ≥177 miles to their provider were more likely to be adherent (OR = 2.88 [95% CI, 1.17-7.55]; <em>P</em> = 0.02).</p></div><div><h3>Conclusions</h3><p>Follow-up adherence for childhood eye care was low but remained relatively stable before and during the COVID-19 pandemic; &gt;50% of children were less-adherent.</p></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S109185312400243X/pdfft?md5=a438b23d08d0c139f0cbf7d2943876c0&pid=1-s2.0-S109185312400243X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141494104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}