{"title":"Gastric modulation of food reward, olfaction and taste in obesity and bariatric surgery: an artificial intelligence assisted scoping review protocol","authors":"Nina Ritsch, Camille Bourque, Frederic Bergeron, Julie-Anne Nazare, Anestis Dougkas, Sylvain Iceta","doi":"10.1101/2024.04.29.24306451","DOIUrl":"https://doi.org/10.1101/2024.04.29.24306451","url":null,"abstract":"<strong>Objective</strong> To understand the extent and nature of the available research on gastric modulation of food reward, olfaction, and taste in people with obesity or those who have undergone bariatric surgery.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140833101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sharine M. Smeets, Jessica C. Kiefte-de Jong, Laura A. van der Velde
{"title":"Food insecurity and other barriers to adherence to a gluten-free diet in individuals with celiac disease and non-celiac gluten sensitivity in the Netherlands: a mixed-methods study","authors":"Sharine M. Smeets, Jessica C. Kiefte-de Jong, Laura A. van der Velde","doi":"10.1101/2024.04.28.24306418","DOIUrl":"https://doi.org/10.1101/2024.04.28.24306418","url":null,"abstract":"<strong>Objectives</strong> To determine the prevalence of food insecurity among individuals with celiac disease (CeD) and non-celiac gluten sensitivity (NCGS) in the Netherlands and explore its association with diet quality and other barriers to adherence to a gluten-free diet.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140833311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parvaneh Parvin, Sanne Boesveldt, Elbrich M. Postma
{"title":"Assessing the Impact of Olfactory Dysfunction on Eating Behavior: A Systematic Scoping Review and Call for Standardized Assessments","authors":"Parvaneh Parvin, Sanne Boesveldt, Elbrich M. Postma","doi":"10.1101/2024.04.15.24305547","DOIUrl":"https://doi.org/10.1101/2024.04.15.24305547","url":null,"abstract":"Olfaction plays a priming role in both the anticipation and consumption phases of eating behavior. Olfactory dysfunction can therefore lead to changes in various aspects of eating behavior, such as food choice, appetite, and food intake. In light of the increasing prevalence of persistent olfactory dysfunction among patients affected by Covid-19, providing proper care and dietary advice to individuals with olfactory dysfunction is imperative. Therefore, this scoping review seeks to gain a better understanding of the impact of olfactory dysfunction on eating behavior. Following the PRISMA guidelines, 49 papers were included, the outcomes were presented by dividing them into two categories: 1) anticipatory eating behavior, including (anticipatory) food liking, appetite and craving, food preferences, food neophobia, and cooking habits; and 2) consummatory behavior, including, food intake, consumption frequency, adherence to dietary guidelines, (experienced) food liking, food enjoyment, and eating habits. Our results show that in the anticipatory phase of eating behavior, food liking and, food preferences and in the consummatory phase, food enjoyment is most affected in people who experienced a sudden change in olfactory function rather than a gradual decline. Moreover, changes in food flavor perception due to olfactory dysfunction, result in a shift of food preferences towards more taste-based preferences, such as salty or savory (i.e., umami) foods. Subsequently, changes in preferences can affect food intake and adherence to dietary guidelines, but only to a limited extent. Appetite is more likely to be low in individuals with short-term olfactory dysfunction compared to those with long-term changes. Generally, eating behavior is more impacted in individuals with a distorted sense of smell than in those with smell loss, and the effect becomes more pronounced over time. Due to the heterogeneity of methods used to measure different aspects of eating behavior, this review stresses the importance of more research on olfaction and eating behavior using standardized and validated assessments. Such research is essential to better understand the effects of olfactory dysfunction on each aspect of eating behavior and provide effective interventions.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140613048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Applying the Nova food classification to food product databases using discriminative ingredients: a methodological proposal","authors":"Mariana Fagundes Grilo, Beatriz Silva Nunes, Ana Clara Duran, Camila Zancheta Ricardo, Larissa Galastri Baraldi, Euridice Martinez Steele, Camila Aparecida Borges","doi":"10.1101/2024.04.12.24305721","DOIUrl":"https://doi.org/10.1101/2024.04.12.24305721","url":null,"abstract":"<strong>Background</strong> Growing interest in the Nova food classification system surged among various stakeholders, driven primarily by compelling evidence linking the consumption of ultra-processed foods (UPF) to negative health outcomes. However, the conventional classification process often leaves room for uncertainty and operational challenges.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"249 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140574866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elise J.M. van Eijnatten, Guido Camps, Wolf Rombouts, Linette Pellis, Paul A.M. Smeets
{"title":"Gastric digestion and amino acid concentrations of casein from cow and goat milk: a randomized crossover trial in healthy men","authors":"Elise J.M. van Eijnatten, Guido Camps, Wolf Rombouts, Linette Pellis, Paul A.M. Smeets","doi":"10.1101/2024.04.10.24305606","DOIUrl":"https://doi.org/10.1101/2024.04.10.24305606","url":null,"abstract":"<strong>Background</strong> <em>In vitro</em> studies show that goat milk proteins form less compact coagulates in the stomach compared to cow milk proteins. This may increase the accessibility of the proteins to digestive enzymes, thereby resulting in enhanced gastric digestion and amino acid (AA) absorption. However, this needs to be confirmed <em>in vivo</em> in humans.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140575015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaomian Tan, Pui Yee Tan, Somphos Vicheth Som, Son Duy Nguyen, Do Thanh Tran, Nga Thuy Tran, Van Khanh Tran, J. Bernadette Moore, Yun Yun Gong
{"title":"Micronutrient deficiencies and the double burden of malnutrition in Vietnamese female adolescents: a national cross-sectional study in 2020","authors":"Xiaomian Tan, Pui Yee Tan, Somphos Vicheth Som, Son Duy Nguyen, Do Thanh Tran, Nga Thuy Tran, Van Khanh Tran, J. Bernadette Moore, Yun Yun Gong","doi":"10.1101/2024.04.11.24305546","DOIUrl":"https://doi.org/10.1101/2024.04.11.24305546","url":null,"abstract":"<strong>Background</strong> Vietnam is facing a double burden of malnutrition, with increasing prevalence of overweight coexisting with undernutrition (stunting or thinness) and micronutrient deficiencies (MNDs). Although malnutrition during female adolescence leads to poor health outcomes with potential intergenerational effects on offspring, no studies have comprehensively investigated MNDs and nutritional status among contemporary Vietnamese female adolescents.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140575080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camila Aparecida Borges, Carolina Kikuta, Beatriz Silva Nunes, Matheus Nascimento Pureza Castro Leite, Mariana Ribeiro, Laís Amaral Mais, Ana Paula Bortoletto Martins, Ana Clara Duran
{"title":"Monitoring the first implementation year of the new nutrition labeling regulations in Brazil","authors":"Camila Aparecida Borges, Carolina Kikuta, Beatriz Silva Nunes, Matheus Nascimento Pureza Castro Leite, Mariana Ribeiro, Laís Amaral Mais, Ana Paula Bortoletto Martins, Ana Clara Duran","doi":"10.1101/2024.04.09.24305563","DOIUrl":"https://doi.org/10.1101/2024.04.09.24305563","url":null,"abstract":"<strong>Objective</strong> This study aimed to monitor the initial 12 months of the implementation of the updated nutrition labeling regulations in Brazil approved in 2020, focusing on the presence and readability of the front-of-package nutrition labeling (FOPNL) on food packages and the presence of added sugars information in the nutrition facts panel.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140575054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valentin Max Vetter, Kamil Demircan, Jan Homann, Thilo Samson Chillon, Michael Mülleder, Orr Shomroni, Elisabeth Steinhagen-Thiessen, Markus Ralser, Christina M. Lill, Lars Bertram, Lutz Schomburg, Ilja Demuth
{"title":"Low Blood Levels of Selenium, Selenoprotein P and GPx3 are Associated with Accelerated Biological Aging: Results from the Berlin Aging Study II (BASE-II)","authors":"Valentin Max Vetter, Kamil Demircan, Jan Homann, Thilo Samson Chillon, Michael Mülleder, Orr Shomroni, Elisabeth Steinhagen-Thiessen, Markus Ralser, Christina M. Lill, Lars Bertram, Lutz Schomburg, Ilja Demuth","doi":"10.1101/2024.04.04.24305314","DOIUrl":"https://doi.org/10.1101/2024.04.04.24305314","url":null,"abstract":"<strong>Introduction</strong> Biological age reflects inter-individual differences in biological function and capacity beyond chronological age. Biological age can be estimated by DNA methylation age (DNAmA) and its deviation from chronological age, DNAmA acceleration (DNAmAA). Low levels of serum selenium, selenoprotein P (SELENOP), and the selenocysteine-containing glutathione peroxidase 3 (GPx3) are associated with adverse health outcomes and selenium supplementation is discussed as an anti-aging intervention.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140602820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maternal Fiber Intake and Perinatal Depression & Anxiety","authors":"Neda Ebrahimi, Tiffany Turner, Faith Gallant, Abinaa Chandrakumar, Roshni Kohli, Rebecca Lester, Victoria Forte, Kieran Cooley","doi":"10.1101/2024.03.24.24304719","DOIUrl":"https://doi.org/10.1101/2024.03.24.24304719","url":null,"abstract":"Background: Dietary fiber can significantly alter gut microbiota composition. The role of gut microbiome in the Gut-Brain Axis and modulation of neuropsychiatric disease is increasingly recognized. The role of antenatal diet, particularly fiber intake, in mitigating maternal mental health disorders remains unexplored. The objective of this review is to investigate the association between maternal fiber intake and perinatal depression and anxiety (PDA). Methods: A literature review of PubMed and Google Scholar was conducted using appropriate keyword/MeSH terms for pregnancy, diet, fiber, and mental health. Observational and clinical trials published between 2015-2021 were included and data pertaining to dietary patterns (DP), food intake, mental health, and demographic data were extracted. The top three fiber-containing food groups (FG) per study were identified using a sum rank scoring system of fiber per 100 grams and fiber per serving size. The consumption of these top three fiber FGs was then ranked for each dietary pattern/group. Mental health outcomes for each study were simplified into three categories of improved, no change, and worsened. The relationship between top three fiber FGs consumed within each DP and mental health outcomes was analyzed using Spearman's correlation. Results: Thirteen of 52 studies met inclusion criteria. Ten (76.9%) studies assessed DPs (7 examined depression only, 2 examined depression and anxiety, and 1 examined anxiety only). Seven (53.9%) studies reported at least one significant positive relationship between mental health outcomes and DPs while 3 reported at least one negative outcome. Three (23.1%) studies compared intake of different food groups between depressed and non-depressed groups. In studies of DPs, the average consumption ranking of the top 3 fiber FGs, bore a significant inverse association with mental health outcomes [r=-0.419(95%CI: -0.672-0.078)] p=0.015. In studies comparing intake of different FGs between depressed and non-depressed groups, consumption of top-ranking fiber foods was higher in the non-depressed groups, but significantly higher in 4 of the 10 high fiber FGs.\u0000Conclusion: This study reframes findings from previously published studies of maternal diet and mental health outcomes to focus on fiber intake specifically, using a fiber ranking system. A significant correlation between lower intake of fiber and poorer mental health outcomes warrants further investigation in future studies.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140302046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia J.M. Roelofs, Guido Camps, Louise M. Leenders, Luca Marciani, Robin C. Spiller, Elise J.M. van Eijnatten, Jaber Alyami, Ruoxuan Deng, Daniela Freitas, Michael Grimm, Leila J. Karhunen, Shanthi Krishnasamy, Steven Le Feunteun, Dileep N. Lobo, Alan R. Mackie, Morwarid Mayar, werner Weitschies, Paul A.M. Smeets
{"title":"Intra- and interindividual variability in fasted gastric content volume","authors":"Julia J.M. Roelofs, Guido Camps, Louise M. Leenders, Luca Marciani, Robin C. Spiller, Elise J.M. van Eijnatten, Jaber Alyami, Ruoxuan Deng, Daniela Freitas, Michael Grimm, Leila J. Karhunen, Shanthi Krishnasamy, Steven Le Feunteun, Dileep N. Lobo, Alan R. Mackie, Morwarid Mayar, werner Weitschies, Paul A.M. Smeets","doi":"10.1101/2024.03.12.24304085","DOIUrl":"https://doi.org/10.1101/2024.03.12.24304085","url":null,"abstract":"Background: Gastric fluid plays a key role in food digestion and drug dissolution, therefore, the amount of gastric fluid present in a fasted state may influence subsequent digestion and drug delivery. We aimed to describe intra- and interindividual variation in fasted gastric content volume (FGCV) and to determine the association with age, sex, and body size characteristics.\u0000Methods: Data from 24 MRI studies measuring FGCV in healthy, mostly young individuals after an overnight fast were pooled. Analysis included 366 participants with a total of 870 measurements. Linear mixed model analysis was performed to calculate intra- and interindividual variability and to assess the effects of age, sex, weight, height, weight*height as a proxy for body size, and body mass index (BMI).\u0000Results: FGCV ranged from 0 to 156 mL, with a mean (SD) value of 33 mL (25 mL). The overall coefficient of variation within the study population was 75.6%, interindividual SD was 15 mL, and the intraindividual SD was 19 mL. Age, weight, height, weight*height, and BMI had no effect on FGCV. Women had lower volumes compared to men (MD: -6 mL), when corrected for the aforementioned factors.\u0000Conclusion: FGCV is highly variable, with higher intraindividual compared to interindividual variability, indicating that FGCV is subject to day-to-day and within-day variation and is not a stable personal characteristic. This highlights the importance of considering FGCV when studying digestion and drug dissolution. Exact implications remain to be studied.","PeriodicalId":501073,"journal":{"name":"medRxiv - Nutrition","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140128812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}