{"title":"Dietary and Behavioral Determinants of Blood Phenylalanine Levels in Children With Phenylketonuria: A Cross-Sectional Study.","authors":"Jiyan Aslan Ceylan","doi":"10.1016/j.pedhc.2026.07.008","DOIUrl":"https://doi.org/10.1016/j.pedhc.2026.07.008","url":null,"abstract":"<p><strong>Introduction: </strong>Maintaining optimal blood phenylalanine (Phe) levels in children with phenylketonuria (PKU) depends on dietary, behavioral, and psychosocial factors. This study examined dietary and behavioral determinants of metabolic control in pediatric PKU.</p><p><strong>Method: </strong>This cross-sectional study included 50 children with PKU. Participants were categorized according to whether their Phe levels were within or above age-specific therapeutic target ranges.</p><p><strong>Results: </strong>The mean Phe level was 536.3 ± 311.7 µmol/L, and 54% of participants had uncontrolled Phe values. Those with uncontrolled Phe levels more frequently exhibited poor dietary adherence, consumption of protein-rich foods, lack of satiety after meals, and social difficulties (p < .05), whereas no associations were observed for age and gender. Intake of protein-rich foods emerged as the strongest independent predictor of elevated Phe levels.</p><p><strong>Conclusion: </strong>Metabolic control in PKU is closely linked to feeding behaviors and psychosocial challenges. Health care providers should address behavioral and social barriers alongside dietary prescriptions to improve long-term Phe control.</p>","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148759692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Keri M Spitler, Andrea Krzyzaniak, Kevin Kuhn, Alexandra S Rooney, Margaret N Mericle, Romeo C Ignacio, Rasheed I Ahmad, Brad Culotta, Michael J Krzyzaniak, Vishal Bansal, Michael J Sise
{"title":"Hospital Type and Clinical Outcomes for Pediatric Lower-Extremity Open Fracture: Implications for Child Health Services Organizations.","authors":"Keri M Spitler, Andrea Krzyzaniak, Kevin Kuhn, Alexandra S Rooney, Margaret N Mericle, Romeo C Ignacio, Rasheed I Ahmad, Brad Culotta, Michael J Krzyzaniak, Vishal Bansal, Michael J Sise","doi":"10.1016/j.pedhc.2026.07.002","DOIUrl":"https://doi.org/10.1016/j.pedhc.2026.07.002","url":null,"abstract":"<p><strong>Objectives: </strong>Evaluate associations between hospital type and clinical outcomes for pediatric lower-extremity open fractures.</p><p><strong>Methods: </strong>Retrospective study of children ≤17 years with lower-extremity open fractures using HCAI (2016-2021). Fractures were categorized as Type I/II or III. Hospitals were categorized as exclusively children's hospitals (ECH), other hospitals with pediatric surgeon coverage (WPS), or without (NPS). Outcomes included time to surgery, length of stay (LOS), discharge disposition, and complications. Multivariate models evaluated associations between hospital type and outcomes.</p><p><strong>Results: </strong>Among 1,118 admissions, 324 (29%) were treated at ECH, 445 (40%) at WPS, and 349 (31%) at NPS. ECH patients had a shorter time to surgery (p = .02), had shorter LOS (p < .001), and were more frequently discharged home (p < .001). Complication rates were similar. Multivariable regression showed WPS and NPS had lower odds of routine home discharge while WPS had longer LOS for isolated fractures.</p><p><strong>Conclusion: </strong>ECH provide more efficient care for pediatric lower-extremity open fractures while maintaining comparable complication rates.</p>","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148763468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Muhammad Shaheer Ahmad, Sarmad Imran, Warda Shahzad, Tooba Shahzad, Muhammad Humza Tahir, Mohammedsadeq A Shweliya
{"title":"Mortality Trends for Infant Intracranial Hemorrhage in the United States, 1999-2020: A 22-year Analysis.","authors":"Muhammad Shaheer Ahmad, Sarmad Imran, Warda Shahzad, Tooba Shahzad, Muhammad Humza Tahir, Mohammedsadeq A Shweliya","doi":"10.1016/j.pedhc.2026.06.007","DOIUrl":"https://doi.org/10.1016/j.pedhc.2026.06.007","url":null,"abstract":"<p><strong>Background: </strong>Intracranial hemorrhage (ICH) is a major cause of infant mortality and neurodevelopmental complications, yet national mortality trends and demographic disparities remain poorly characterized.</p><p><strong>Methods: </strong>A retrospective analysis using the CDC WONDER Multiple Cause of Death database (1999-2020) identified infant (<1 year) deaths with ICH (ICD-10 P52) as an underlying or contributing cause. Mortality rates per 100,000 live births were calculated by demographic and geographic factors, and Joinpoint regression estimated annual and average annual percent changes (APC, AAPC) with 95% confidence intervals.</p><p><strong>Results: </strong>From 1999 to 2020, 20,544 infant ICH deaths were recorded in the United States, with a crude rate of 23.64 per 100,000 live births. Mortality peaked in 2003 at 31.57 and declined to 17.32 by 2020 (AAPC -2.51%). Among 20,544 ICH infant deaths recorded , mortality declined from 31.57 (2003) to 17.32 (2020) (AAPC -2.51%). Males exceeded females (28.18 vs. 18.88), Non-Hispanic Blacks had the highest racial rate (37.5), and Southern states showed the greatest regional burden. Urban areas declined faster than rural (AAPC -2.53% vs. -1.89%).</p><p><strong>Conclusions: </strong>Despite substantial overall decline in infant ICH rates, persistent disparities by sex, race, region, and urbanization underscore the need for equitable maternal and infant healthcare.</p>","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148763722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cody Dalton, Eli Isenberg, Brock Crockett-Beck, Zoona Sarwar, Jeremy Johnson, Catherine J Hunter
{"title":"Management and Outcomes of Pediatric Dog Bites at a Single Institution.","authors":"Cody Dalton, Eli Isenberg, Brock Crockett-Beck, Zoona Sarwar, Jeremy Johnson, Catherine J Hunter","doi":"10.1016/j.pedhc.2026.06.016","DOIUrl":"https://doi.org/10.1016/j.pedhc.2026.06.016","url":null,"abstract":"<p><strong>Objectives: </strong>Pediatric dog bite injuries are a common cause of emergency department. This study aimed to characterize management, and outcomes of pediatric dog bite injuries at a tertiary care center and identify implications for pediatric emergency practitioners.</p><p><strong>Methods: </strong>A retrospective chart review was conducted of patients with dog bite injuries over two-years at a single pediatric tertiary care center. Descriptive statistical analysis was performed on injury characteristics, management, and outcomes.</p><p><strong>Results: </strong>Most injuries occurred in familiar environments. Facial injuries were most common (83%). Nearly all patients (98.9%) required laceration repair mostly in the emergency department. Most patients had antibiotics. Minimal complications were observed and were primarily cosmetic.</p><p><strong>Conclusions: </strong>Pediatric dog bite injuries most frequently involve the face and are typically managed nonoperatively. Multidisciplinary consultation is often required, particularly for complex facial injuries. This supports prompt assessment, appropriate wound management, and targeted antibiotic use in pediatric emergency care.</p>","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Halenur Teke, Mehri Durak, Selcuk Teke, Burcin Ozlem Ates, Seda Bozduman Celebi, Mehmet Ayhan Congologlu, Necati Balamtekin
{"title":"Associations Between Weight Status, Peer Victimization, and Mental Health in Clinically Referred Children: A Cross-Sectional Study.","authors":"Halenur Teke, Mehri Durak, Selcuk Teke, Burcin Ozlem Ates, Seda Bozduman Celebi, Mehmet Ayhan Congologlu, Necati Balamtekin","doi":"10.1016/j.pedhc.2026.06.015","DOIUrl":"https://doi.org/10.1016/j.pedhc.2026.06.015","url":null,"abstract":"<p><strong>Introduction: </strong>To examine peer victimization, internalizing symptoms, and psychiatric disorders in underweight and obese clinically referred youth versus normal-weight peers.</p><p><strong>Methods: </strong>Cross-sectional study of 161 children aged 7-17 (51 underweight, 57 normal-weight, 53 obese). Victimization was measured using the Olweus Bully/Victim Questionnaire, depressive and anxiety symptoms with the CDI and STAI-C trait, and psychiatric diagnoses with the K-SADS-PL.</p><p><strong>Results: </strong>Peer victimization and anxiety disorders were higher in underweight and obese than normal-weight children (p < .001 and p = .005, respectively). Trait anxiety symptoms were elevated in both groups (p < .001), whereas depressive symptoms did not differ. Victimized youth had higher rates of anxiety (p = .009) and depressive disorders (p = .001). In adjusted models, underweight predicted anxiety disorder (OR 5.03, p = .010), underweight (OR 4.19, p = .003) and obesity (OR 9.00, p < .001) predicted victimization, and victimization predicted depressive disorder (OR 3.03, p = .016).</p><p><strong>Discussion: </strong>Weight extremes in clinically referred children are linked to peer victimization and internalizing problems, supporting routine psychosocial screening in clinical practice.</p>","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aymee Steidl, Jenna McHale, Stephen Harmon, Jennifer Sonney
{"title":"Spirometry Monitoring and Asthma Responsibility in Kids (SMARt-Kids): A Mixed-Methods Study.","authors":"Aymee Steidl, Jenna McHale, Stephen Harmon, Jennifer Sonney","doi":"10.1016/j.pedhc.2026.06.014","DOIUrl":"10.1016/j.pedhc.2026.06.014","url":null,"abstract":"<p><strong>Introduction: </strong>Asthma affects 4.6 million U.S. children, and home spirometry offers a promising monitoring tool, yet research on its use in children is limited. This study explored feasibility, acceptability, usability, barriers, facilitators, and management responsibility of home spirometry in school-aged children with persistent asthma.</p><p><strong>Methods: </strong>A convergent mixed-methods design was used to assess home spirometry feasibility, acceptability, usability, and management responsibility in 11 parent-child dyads (children aged 7-11), sampled from a completed RCT (NCT04908384).</p><p><strong>Results: </strong>Both parents and children found home spirometry feasible and acceptable. Parents valued real-time lung function tracking but identified usability issues and technological challenges as barriers. Responsibility scores indicated shared management, though interviews revealed predominantly parent-driven use.</p><p><strong>Discussion: </strong>Home spirometry is feasible and acceptable for families with school-aged children with asthma; however, technological barriers complicate use. Family-centered education and integration of home spirometry into routine care may help clinicians detect early changes in asthma control.</p>","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13416703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148609673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of the Blues: Pseudochromhidrosis in an Adolescent Following Injury.","authors":"Alyssa L Kesselman","doi":"10.1016/j.pedhc.2026.06.012","DOIUrl":"https://doi.org/10.1016/j.pedhc.2026.06.012","url":null,"abstract":"<p><p>Pseudochromhidrosis is an underrecognized cause of unusual skin discoloration but is important to include in the differential diagnosis of skin discoloration. This case presents a 17-year-old female with intermittent bright blue discoloration of the right elbow and upper arm following prior orthopedic injuries, prompting extensive evaluation with normal imaging, cardiologic evaluation, and laboratory findings by multiple specialists. Bacterial culture suggested a chromogenic organism consistent with pseudochromhidrosis. Treatment with systemic erythromycin and topical clindamycin resulted in complete and sustained resolution. This case highlights the importance of early recognition of pseudochromhidrosis in preventing unnecessary diagnostic procedures and facilitating timely treatment.</p>","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148594255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lauren Head Zauche, Sabrina A Madni, David K Shay, Christine K Olson, Erin Stroud, Andrea J Sharma
{"title":"Neonatal and Infant Health Outcomes Following Maternal COVID-19 Vaccination: CDC's COVID-19 Vaccine Pregnancy Registry.","authors":"Lauren Head Zauche, Sabrina A Madni, David K Shay, Christine K Olson, Erin Stroud, Andrea J Sharma","doi":"10.1016/j.pedhc.2026.06.017","DOIUrl":"10.1016/j.pedhc.2026.06.017","url":null,"abstract":"<p><strong>Introduction: </strong>The COVID-19 Vaccine Pregnancy Registry (C19VPR) monitored pregnant women vaccinated for COVID-19 during December 2020 to June 2021. We report incidence of health outcomes among infants of C19VPR participants.</p><p><strong>Methods: </strong>Data about birthweight (e.g., low birthweight [LBW] <2,500 grams), small-for-gestational-age (SGA), death, and 10 prespecified conditions (i.e., cardiac arrest, cardiomyopathy, congenital hearing loss, heart failure, hypoxic-ischemic encephalopathy, intussusception, myocarditis/pericarditis, seizures, stroke, and supraventricular tachycardia) were collected through phone interviews from birth through 3 months postpartum; among a subsample, interviews extended through 15 months postpartum. Incidence of each prespecified condition was compared with prepandemic estimates.</p><p><strong>Results: </strong>Of 19,852 infants with 3-month follow-up data, 125 (0.6%) had at least one prespecified condition. Estimated C19VPR incidences for these conditions, LBW, SGA, and death, were within or below ranges reported in prepandemic studies.</p><p><strong>Conclusion: </strong>The incidence of LBW, SGA, death, or each of 10 prespecified infant conditions in C19VPR did not exceed prepandemic estimates.</p>","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13636450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148550942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Smith, Christy A Leyland, Margaret MacKay, Matthew K Icard, Rémi Hueckel
{"title":"A Case Study on Bronchiolitis Management: Quality Improvement, Guideline Utilization, and Resource Stewardship in the Pediatric Emergency Department.","authors":"Sarah Smith, Christy A Leyland, Margaret MacKay, Matthew K Icard, Rémi Hueckel","doi":"10.1016/j.pedhc.2026.06.011","DOIUrl":"https://doi.org/10.1016/j.pedhc.2026.06.011","url":null,"abstract":"","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Key to Early Diagnosis: Retropharyngeal Abscess Masked by Neck Extension Limitation in a Pediatric Patient.","authors":"Ayfer Şahin, Meryem Coşkun","doi":"10.1016/j.pedhc.2026.06.013","DOIUrl":"https://doi.org/10.1016/j.pedhc.2026.06.013","url":null,"abstract":"<p><p>Retropharyngeal abscess (RFA) is a rare but potentially life-threatening deep neck infection in children and may lead to airway obstruction, mediastinitis, vascular complications, and other severe outcomes. In the pediatric population, RFA typically develops as a result of lymph node suppuration in this region secondary to an upper respiratory tract infection. We present the case of an 8-year-old boy who presented to the pediatric emergency department with sore throat, dysphagia, and nasal congestion. Because restricted neck extension raised suspicion for a deep neck infection, the patient was referred for otolaryngologic evaluation. The diagnosis of RFA was established based on characteristic findings on computed tomography, supported by the laboratory results. The patient was admitted to the hospital for treatment and was discharged after receiving parenteral antibiotic therapy. This case highlights the importance of careful head and neck examination, prompt recognition of restricted neck movement, and timely imaging in children with subtle upper respiratory tract symptoms.</p>","PeriodicalId":50094,"journal":{"name":"Journal of Pediatric Health Care","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}