解释血清特异性IgE组：儿科医生诊断儿童食物过敏的关键见解。

IF 1.8 4区医学 Q2 HEALTH POLICY & SERVICES

Journal of Pediatric Health Care Pub Date : 2025-08-09 DOI:10.1016/j.pedhc.2025.07.004

Kaity Fashho, Matthew Garber, Ejaz Yousef

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引用次数: 0

摘要

背景：本研究是由一个5岁男孩的病例引起的，他的初级保健医生根据血清特异性IgE （sige）测试被误诊为“多种食物过敏”，尽管他食用了可疑的过敏原没有问题。本回顾性研究的目的是评估sigg面板测试诊断儿童食物过敏的准确性。方法：通过病例报告和回顾性研究，评价SSIgE试验诊断儿童食物过敏的准确性。该研究包括646名接受口腔食物挑战的患者。结果：结果表明，虽然ssigg检测具有较高的阴性预测值，但其特异性较差，导致不必要的食物回避。结论：研究结果强调了谨慎解释ssigg测试的必要性，并建议口服挑战以准确诊断，旨在防止不必要的饮食限制的负面影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Interpreting Serum-Specific IgE Panels: Key Insights for Pediatricians in Diagnosing Food Allergies in Children.

Background: This study was prompted by a case of a 5-year-old boy misdiagnosed with "multiple food allergies" based on serum-specific IgE (SSIgE) tests ordered by his primary care physician, despite consuming the suspected allergens without issues. The purpose of this retrospective study was to evaluate the accuracy of SSIgE panel testing in diagnosing food allergies in children.

Methods: Case report and retrospective study to evaluate the accuracy of SSIgE tests in diagnosing food allergies in children. The study included 646 patients who underwent oral food challenges.

Results: Results indicated that while SSIgE tests have high negative predictive value, their specificity is poor, leading to unnecessary food avoidance.

Conclusions: The findings highlight the need for cautious interpretation of SSIgE tests and recommend oral challenges for accurate diagnosis, aiming to prevent the negative impact of unnecessary dietary restrictions.

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来源期刊

Journal of Pediatric Health Care NURSING-PEDIATRICS

CiteScore

3.40

自引率

10.70%

发文量

140

审稿时长

24 days

期刊介绍： The Journal of Pediatric Health Care, the official journal of the National Association of Pediatric Nurse Practitioners, provides scholarly clinical information and research regarding primary, acute and specialty health care for children of newborn age through young adulthood within a family-centered context. The Journal disseminates multidisciplinary perspectives on evidence-based practice and emerging policy, advocacy and educational issues that are of importance to all healthcare professionals caring for children and their families.